Abstract:
:Serum total androgens were estimated by radioimmunoassay on blood samples of treatment-seeking homosexuals and heterosexual controls. There was no significant difference in androgen levels between the homosexual and control group, nor was there any relationship between androgen levels and response to treatment. These results suggest that androgen levels have no aetiological significance in treatment-seeking homosexuals and have no relevance as indicators of treatment outcome.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
James S,Carter RA,Orwin Adoi
10.1017/s0033291700004396subject
Has Abstractpub_date
1977-08-01 00:00:00pages
427-9issue
3eissn
0033-2917issn
1469-8978journal_volume
7pub_type
杂志文章abstract::A detailed analysis of the results of a multi-centre clinical trial shows that, while the relapse rate following recovery from an operationally defined depressive illness was smaller among patients subsequently treated with either amitryptiline or lithium than with a placebo, there was no clinically significant differ...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700003068
更新日期:1984-02-01 00:00:00
abstract:BACKGROUND:Few population studies have investigated the functional disabilities that accompany specific psychiatric diagnoses. This study assesses the nature and strength of current and residual impairments in various functional domains of life. METHODS:Data were derived from the Netherlands Mental Health Survey and I...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799001841
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Patients with anorexia nervosa (AN) run a high risk of becoming chronically ill and of dying. In the acute phase of their illness they present with numerous physical and laboratory abnormalities. However, little is known about the long-term prognostic value of these findings or about the medical morbidity in...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004394
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:There are considerable differences between and within countries in the involvement of general practitioners (GPs) in psychosocial care. This study aimed to describe the self-perceived role of GPs in 30 European countries as the first contacted professional for patients with psychosocial problems. and to exam...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329179900851x
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Aberrant functional connectivity within the default network is generally assumed to be involved in the pathophysiology of obsessive compulsive disorder (OCD); however, the genetic risk of default network connectivity in OCD remains largely unknown. METHOD:Here, we systematically investigated default network...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713002250
更新日期:2014-05-01 00:00:00
abstract::A meta-analysis was carried out on 53 cases of dementia praecox (DP) and 134 cases of manic-depressive insanity (MDI) originally diagnosed by Kraepelin or his collaborators in Munich in 1908. The original case material was coded in terms of Present State Examination syndromes and analysed statistically for internal co...
journal_title:Psychological medicine
pub_type: 传,历史文章,杂志文章,meta分析
doi:10.1017/s0033291700026337
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:According to the stress sensitization hypothesis, prior exposure to extreme stressors may lead to increased responsiveness to subsequent stressors. It is unclear whether disaster exposure is associated with stress sensitization and, if so, whether this effect is lasting or temporary. This study aimed to inve...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002765
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:We studied to what extent internet-based cognitive behaviour therapy (CBT) programs for symptoms of depression and anxiety are effective. METHOD:A meta-analysis of 12 randomized controlled trials. RESULTS:The effects of internet-based CBT were compared to control conditions in 13 contrast groups with a tot...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291706008944
更新日期:2007-03-01 00:00:00
abstract::Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032748
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:A few previous studies suggest that a large number of individuals do not present at hospital following a suicide attempt, complicating recurrence prevention and prevalence estimation. METHODS:Data were extracted from a regular phone survey in representative samples of the French population aged 18-75 years ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720002305
更新日期:2020-07-03 00:00:00
abstract::Results are reported from a large population study (of working people) comparing Holocaust survivors and a control group in regard to emotional distress, satisfaction in life and psychosomatic symptoms. It was found that, even 40 years after the traumatic experience, this group of survivors exhibited a slightly higher...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700002580
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Delusion is the most characteristic symptom of psychosis. While researchers suggested an association between changes of the cortical salience network (CSN) and delusion, whether these CSN findings are a cause or a consequence of delusion remains unknown. METHOD:To assess the effect of CSN functioning to for...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716001057
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Abnormal perceptions of food and shape underpin the cognitive behavioural model of eating disorders (EDs). The aim of this study was to investigate motivational processing of disorder-specific and standard emotional cues in anorexia (AN) and bulimia nervosa (BN) using startle eyeblink modulation (SEM). SEM w...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706008129
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, and associated brain functions may be affected by trauma exposure in psychotic disorders. We aimed to identify the influence of trauma-exposure on brain activation and func...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002884
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Relapse is distressingly common after the first episode of psychosis, yet it is poorly understood and difficult to predict. Investigating changes in cognitive function preceding relapse may provide new insights into the underlying mechanism of relapse in psychosis. We hypothesized that relapse in fully remit...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291716000751
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Frequency and quantity of alcohol consumption are metrics commonly used to measure alcohol consumption behaviors. Epidemiological studies indicate that these alcohol consumption measures are differentially associated with (mental) health outcomes and socioeconomic status (SES). The current study aims to eluc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719000357
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Post-traumatic stress disorder (PTSD) has been called one of the signature injuries of the Iraq War. In this review prevalence estimates of PTSD are summarized and discrepancies are discussed in relation to methodological differences between studies. METHOD:We searched for population-based studies with a mi...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291709990791
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed. METHOD:Antecedent, concurrent and predictive markers of construct validity were examined for three models of PDs: the Five-Factor Model (FFM), the...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706009482
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Social media platforms have long been recognised as major disseminators of health misinformation. Many previous studies have found a negative association between health-protective behaviours and belief in the specific form of misinformation popularly known as 'conspiracy theory'. Concerns have arisen regardi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000224X
更新日期:2020-06-09 00:00:00
abstract:BACKGROUND:Based on the developing clinical and legal literature, and using the framework adopted in draft legislation, capacity to make a valid decision about a clinically required blood test was investigated in three groups of people with a 'mental disability' (i.e. mental illness (chronic schizophrenia), 'learning d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700001768
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:The World Mental Health Survey Initiative (WMHSI) has advanced our understanding of mental disorders by providing data suitable for analysis across many countries. However, these data have not yet been fully explored from a cross-national lifespan perspective. In particular, there is a shortage of research o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001116
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Preclinical and human studies suggest an association between chronic inflammation and the development of depressive behaviors. This is proposed to occur through downstream effects of inflammatory cytokines on neuroplasticity, neurogenesis and neurotransmitter function, although the neural correlates remain p...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002940
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) is a chronic, relapsing mental illness. Selective serotonin reuptake inhibitors block serotonin transporters (SERTs) and are the mainstay of treatment for OCD. SERT abnormalities are reported in drug-free patients with OCD, but it is not known what happens to SERT levels d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001865
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The effects of antidepressants for treating depressive disorders have been overestimated because of selective publication of positive trials. Reanalyses that include unpublished trials have yielded reduced effect sizes. This in turn has led to claims that antidepressants have clinically insignificant advanta...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291713000457
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Discriminating Alzheimer's disease (AD) and mild cognitive impairment (MCI) from depression is a challenge in psychogeriatric medicine. A study was set up to ascertain whether cued recall could be useful in differentiating early AD and MCI from depression among elderly individuals. METHOD:The Visual Associa...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170600955X
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Schizophrenia patients have a higher prevalence of type 2 diabetes mellitus with impaired glucose tolerance (IGT) than normals. We examined the relationship between IGT and clinical phenotypes or cognitive deficits in first-episode, drug-naïve (FEDN) Han Chinese patients with schizophrenia. METHOD:A total o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716001902
更新日期:2016-11-01 00:00:00
abstract::Experts have raised concerns that oxytocin for labor induction and augmentation may have detrimental effects on the neurodevelopment of children. To investigate whether there is the reason for concern, we reviewed and evaluated the available evidence by searching databases with no language or date restrictions up to 9...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291718003021
更新日期:2019-04-01 00:00:00
abstract::Schizophrenia and affective disorders selected according to the Feighner criteria can be differentiated on the basis of 40-year outcome. Within schizophrenia the presence of disorganized thoughts at the index admission was associated with poor outcome, whereas better outcome was associated with the presence of delusio...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700052107
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND:Patients may present with cognitive impairment in the euthymic phase of affective disorder, but it is unclear whether the impairment is prevalent before onset of the illness. The aim of the present study was to examine the hypothesis that genetic liability to affective disorder is associated with cognitive i...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706007896
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We investigated the predictions that older adults with ID should have...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708003334
更新日期:2009-01-01 00:00:00