Continuation therapy with lithium and amitriptyline in unipolar depressive illness: a randomized, double-blind, controlled trial.

Abstract:

:A detailed analysis of the results of a multi-centre clinical trial shows that, while the relapse rate following recovery from an operationally defined depressive illness was smaller among patients subsequently treated with either amitryptiline or lithium than with a placebo, there was no clinically significant difference between the prophylactic efficacy of the 2 antidepressants. An account is given of the relative adverse effects of the treatments, and the implications of the findings are discussed.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Glen AI,Johnson AL,Shepherd M

doi

10.1017/s0033291700003068

subject

Has Abstract

pub_date

1984-02-01 00:00:00

pages

37-50

issue

1

eissn

0033-2917

issn

1469-8978

journal_volume

14

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::National statistics for railway fatalities in England and Wales show a reduction of train crashes and a fluctuating level of deaths, of which an increasing proportion is from suicide. A closer examination of a two-year sample from the South of England revealed a large proportion of probable suicides and a small propor...

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    authors: Symonds RL

    更新日期:1985-08-01 00:00:00

  • Determination of shared genetic etiology and possible causal relations between tobacco smoking and depression.

    abstract:BACKGROUNDS:Cigarette smoking is strongly associated with major depressive disorder (MDD). However, any genetic etiology of such comorbidity and causal relations is poorly understood, especially at the genome-wide level. METHODS:In the present in silico research, we analyzed summary data from the genome-wide associati...

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    authors: Yao Y,Xu Y,Cai Z,Liu Q,Ma Y,Li AN,Payne TJ,Li MD

    更新日期:2020-04-06 00:00:00

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    abstract:BACKGROUND:The mechanisms that contribute to emotion dysregulation in anxiety disorders are not well understood. Two common disorders, generalized anxiety disorder (GAD) and panic disorder (PD), were examined to test the hypothesis that both disorders are characterized by hypo-activation in prefrontal cortex (PFC) duri...

    journal_title:Psychological medicine

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    doi:10.1017/S0033291712002383

    authors: Ball TM,Ramsawh HJ,Campbell-Sills L,Paulus MP,Stein MB

    更新日期:2013-07-01 00:00:00

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    abstract:BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...

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    doi:10.1017/s0033291797006405

    authors: Smith GN,Kopala LC,Lapointe JS,MacEwan GW,Altman S,Flynn SW,Schneider T,Falkai P,Honer WG

    更新日期:1998-05-01 00:00:00

  • History of childhood sexual or physical abuse in Japanese patients with eating disorders: relationship with dissociation and impulsive behaviours.

    abstract:BACKGROUND:Empirical data regarding prevalence of sexual and physical abuse histories in Japanese patients with eating disorders is lacking, in contrast to Western countries. This study investigated the prevalence of traumatic events in Japanese patients with eating disorders, and examined the relationship between such...

    journal_title:Psychological medicine

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    doi:10.1017/s0033291799008557

    authors: Nagata T,Kiriike N,Iketani T,Kawarada Y,Tanaka H

    更新日期:1999-07-01 00:00:00

  • The development and validation of a predictive index for postpartum depression.

    abstract::A sample of over 6000 women was recruited in the last trimester of pregnancy and administered a 40-item self-report questionnaire designed to detect the presence of factors that were likely to increase the risk of postpartum depression. The mental state of almost 5000 of these women was determined at around 6 to 8 wee...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700035698

    authors: Cooper PJ,Murray L,Hooper R,West A

    更新日期:1996-05-01 00:00:00

  • Sibling pairs with affective disorders: resemblance of demographic and clinical features.

    abstract:BACKGROUND:As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD:Data on age at onset, g...

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    authors: O'Mahony E,Corvin A,O'Connell R,Comerford C,Larsen B,Jones R,McCandless F,Kirov G,Cardno AG,Craddock N,Gill M

    更新日期:2002-01-01 00:00:00

  • Psychometric assessment of psychiatric disorders in people with learning difficulties (mental handicap): a review of measures.

    abstract::Instruments designed to assess psychiatric disorders in people with learning difficulties (mental handicap) were critically reviewed from a psychometric perspective. Major trends were found in the assessment of psychopathology related to DSM-III and depressive disorders although research in other areas was patchy. Alt...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/s0033291700014732

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    更新日期:1991-02-01 00:00:00

  • The influence of immigrant status and concentration on psychiatric disorder in Canada: a multi-level analysis.

    abstract:BACKGROUND:Many studies have reported an increased incidence of psychiatric disorder (particularly psychotic disorders) among first generation adult immigrants, along with an increasing risk for ethnic minorities living in low-minority concentration neighborhoods. These studies have depended mostly on European case-bas...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711000213

    authors: Menezes NM,Georgiades K,Boyle MH

    更新日期:2011-10-01 00:00:00

  • Abortion and subsequent depressive symptoms: an analysis of the National Longitudinal Study of Adolescent Health.

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    pub_type: 杂志文章

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    authors: Gomez AM

    更新日期:2018-01-01 00:00:00

  • A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect.

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    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究

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    authors: Jaya ES,Ascone L,Lincoln TM

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  • Clinically diagnosed presenile dementia of the Alzheimer type in the Northern Health Region: ascertainment, prevalence, incidence and survival.

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    authors: Newens AJ,Forster DP,Kay DW,Kirkup W,Bates D,Edwardson J

    更新日期:1993-08-01 00:00:00

  • Familiality and SNP heritability of age at onset and episodicity in major depressive disorder.

    abstract:BACKGROUND:Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this study are to investigate...

    journal_title:Psychological medicine

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    authors: Ferentinos P,Koukounari A,Power R,Rivera M,Uher R,Craddock N,Owen MJ,Korszun A,Jones L,Jones I,Gill M,Rice JP,Ising M,Maier W,Mors O,Rietschel M,Preisig M,Binder EB,Aitchison KJ,Mendlewicz J,Souery D,Hauser J,

    更新日期:2015-07-01 00:00:00

  • Preschool psychiatric disorders: homotypic and heterotypic continuity through middle childhood and early adolescence.

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    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0033291713002377

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  • Resource activation for treating post-traumatic stress disorder, co-morbid symptoms and impaired functioning: a randomized controlled trial in Cambodia.

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    journal_title:Psychological medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0033291716002592

    authors: Steinert C,Bumke PJ,Hollekamp RL,Larisch A,Leichsenring F,Mattheß H,Sek S,Sodemann U,Stingl M,Ret T,Vojtová H,Wöller W,Kruse J

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  • Dietary intake and clinical, anthropometric and biochemical indices of malnutrition in elderly demented patients and non-demented subjects.

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    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700012423

    authors: Burns A,Marsh A,Bender DA

    更新日期:1989-05-01 00:00:00

  • The dynamic nature of depression: a new micro-level perspective of mental disorder that meets current challenges.

    abstract::The examination of moment-to-moment, 'micro-level' patterns of experience and behaviour using experience sampling methodology has contributed to our understanding of the 'macro-level' development of full-blown symptoms and disorders. This paper argues that the micro-level perspective can be used to identify the smalle...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291713001979

    authors: Wichers M

    更新日期:2014-05-01 00:00:00

  • Explaining why childhood abuse is a risk factor for poorer clinical course in bipolar disorder: a path analysis of 923 people with bipolar I disorder.

    abstract:BACKGROUND:Childhood abuse is a risk factor for poorer illness course in bipolar disorder, but the reasons why are unclear. Trait-like features such as affective instability and impulsivity could be part of the explanation. We aimed to examine whether childhood abuse was associated with clinical features of bipolar dis...

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    pub_type: 杂志文章

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    authors: Marwaha S,Briley PM,Perry A,Rankin P,DiFlorio A,Craddock N,Jones I,Broome M,Gordon-Smith K,Jones L

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    authors: Cassidy F,Ahearn E,Murry E,Forest K,Carroll BJ

    更新日期:2000-03-01 00:00:00

  • Educational consequences of mental disorders treated in hospital. A 31-year follow-up of the Northern Finland 1966 Birth Cohort.

    abstract:BACKGROUND:Mental disorders often begin during the formative years of education. They may disrupt education and lead to social underachievement. METHODS:We examined the impact of mental disorders treated in hospital (ages 16-29) on educational attainment up to 31 years in the Northern Finland 1966 Birth Cohort (N = 10...

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    pub_type: 杂志文章

    doi:10.1017/s003329170100304x

    authors: Isohanni I,Jones PB,Järvelin MR,Nieminen P,Rantakallio P,Jokelainen J,Croudace TJ,Isohanni M

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  • The views and outcomes of consenting and non-consenting patients receiving ECT.

    abstract:BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

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    更新日期:1999-01-01 00:00:00

  • Personality characteristics of the parents of autistic individuals.

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    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700027938

    authors: Piven J,Wzorek M,Landa R,Lainhart J,Bolton P,Chase GA,Folstein S

    更新日期:1994-08-01 00:00:00

  • One-year outcome of unexplained fatigue syndromes in primary care: results from an international study.

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    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0033291703007566

    authors: Skapinakis P,Lewis G,Mavreas V

    更新日期:2003-07-01 00:00:00

  • Antidepressant use and work-related injuries.

    abstract:BACKGROUND:Adverse effects of antidepressants are most common at the beginning of the treatment, but possible also later. We examined the association between antidepressant use and work-related injuries taking into account the duration of antidepressant use. METHOD:Antidepressant use and work-related injuries between ...

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    pub_type: 杂志文章

    doi:10.1017/S0033291715002925

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    更新日期:2016-05-01 00:00:00

  • Reduced directed forgetting for negative words suggests schizophrenia-related disinhibition of emotional cues.

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    doi:10.1017/S0033291713000445

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    更新日期:2013-11-01 00:00:00

  • The neural basis of flashback formation: the impact of viewing trauma.

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    更新日期:2013-07-01 00:00:00

  • Use of item response theory to understand differential functioning of DSM-IV major depression symptoms by race, ethnicity and gender.

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