Abstract:
:Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neostriatal psychological functions.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Brown KW,White T,Palmer Ddoi
10.1017/s0033291700032748subject
Has Abstractpub_date
1992-02-01 00:00:00pages
69-77issue
1eissn
0033-2917issn
1469-8978journal_volume
22pub_type
杂志文章abstract:BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006405
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Reward dysfunction is a major dimension of depressive symptomatology, but it remains obscure if that dysfunction varies across different reward types. In this study, we focus on the abnormalities in anticipatory/consummatory processing of monetary and social reward associated with depressive symptoms. METHO...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003967
更新日期:2020-11-04 00:00:00
abstract:BACKGROUND:There is increasing recognition that, in addition to negative psychological consequences of trauma such as post-traumatic stress disorder (PTSD), some individuals may develop post-traumatic growth (PTG) following such experiences. To date, however, data regarding the prevalence, correlates and functional sig...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714001202
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Feedback learning is essential for behavioral development. We investigated feedback learning in relation to behavior problems after pediatric traumatic brain injury (TBI). METHOD:Children aged 6-13 years diagnosed with TBI (n = 112; 1.7 years post-injury) were compared with children with traumatic control (...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000106
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718002039
更新日期:2019-05-01 00:00:00
abstract::A sample of 77 women of high and low noise sensitivity in 1977, living in areas of high and low exposure to aircraft noise, were interviewed in the community in 1980. High, intermediate and low noise sensitive women were compared, using measures of blood pressure, heart rate, skin conductance, hearing threshold, uncom...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700023539
更新日期:1985-05-01 00:00:00
abstract::Forty-eight couples with a presenting problem of female sexual unresponsiveness were treated in a controlled study using a balanced factorial design. The factors varied in this design were medication (testosterone or placebo), treatment frequency (weekly or monthly sessions), and the number of therapists involved (one...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700050091
更新日期:1983-02-01 00:00:00
abstract:BACKGROUND:Paranoia is one of the commonest symptoms of psychosis but has rarely been studied in a population at risk of developing psychosis. Based on existing theoretical models, including the proposed distinction between ‘poor me’ and ‘bad me’ paranoia, we aimed to test specific predictions about associations betwee...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1017/S0033291715000689
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The development of childhood anxiety disorders (CADs) is likely to depend on pathways that can be programmed by early-life risk factors. We test the hypothesis that early-life maternal factors can predict this programming effect on CAD. METHODS:Data were obtained from 198 women and children from the Mercy P...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720002147
更新日期:2020-06-29 00:00:00
abstract:BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000542
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:To assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States. METHOD:Data came from a large representative sample of the US population. F...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991231
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Outcome studies of chronic fatigue, neurasthenia and other unexplained fatigue syndromes are few and have been carried out in developed Western countries. This paper aimed to study the outcome of unexplained fatigue syndromes in an international primary care sample and to identify risk factors for persistenc...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/s0033291703007566
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Pharmaceutical industry funding of psychiatric research has increased significantly in recent decades, raising the question of a relationship between pharmaceutical company funding of clinical psychiatric studies and the outcomes of those studies. This study examines this relationship. METHOD:Abstracts of a...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706008567
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:A growing body of neuropsychological and neurobiological research shows a relationship between functioning of the prefrontal cortex and criminal and violent behaviour. The prefrontal cortex is crucial for executive functions such as inhibition, attention, working memory, set-shifting and planning. A deficit ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000241
更新日期:2017-07-01 00:00:00
abstract::We found diurnal weight gain to be abnormal among 28 institutionalized chronically psychotic patients. They were weighed daily for 15 days at 7 a.m. and 4 p.m. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and th...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700011065
更新日期:1989-02-01 00:00:00
abstract::Bilateral electrodermal orienting responses were measured to repeated auditory stimuli in schizophrenic patients and controls. In 3 studies phasic activity to moderate intensity sounds of patients on no drugs or phenothiazines was predominantly hyper- or hypo-responsive. Controls showed moderate or slow habituation. P...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700053319
更新日期:1981-02-01 00:00:00
abstract:BACKGROUND:Learning and memory impairments in older adults with depression are linked to hippocampal atrophy. However, other subcortical regions may also be contributing to these deficits. We aimed to examine whether anterior caudate nucleus volume is significantly reduced in older adults with depression compared to co...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000787
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Sternberg's Memory Scanning Test (MST) is a useful paradigm for evaluating the speed and efficiency of information processing in working memory. Unfortunately, the classical MST has major drawbacks for use in applied settings such as the clinic. For example, its administration time is long and the test is to...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707000360
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Several studies during recent years have reported an increased occurrence of schizophrenia in selected immigrant groups. However, difficulties in establishing the population denominator for immigrant rates of mental disorder, selective referral for treatment, and other problems may have influenced such resul...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797004741
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719000618
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Cognitive behavioral therapy (CBT) can be delivered efficaciously through various modalities, including telephone (T-CBT) and face-to-face (FtF-CBT). The purpose of this study was to explore predictors of outcome in T-CBT and FtF-CBT for depression. METHOD:A total of 325 depressed participants were randomiz...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291715001208
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Previous imaging studies have revealed that acute major depression is characterized by altered neural responses to negative emotional stimuli. Typically, responses in limbic regions such as the amygdala are increased while activity in cortical regulatory regions such as the dorsolateral prefrontal cortex (DL...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709990596
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:The coronavirus [coronavirus disease 2019 (COVID-19)] pandemic has introduced extraordinary life changes and stress, particularly in adolescents and young adults. Initial reports suggest that depression and anxiety are elevated during COVID-19, but no prior study has explored changes at the within-person lev...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005358
更新日期:2021-01-13 00:00:00
abstract:BACKGROUND:Advanced paternal age is associated with increased risk of schizophrenia. This study aimed to explore whether older paternal age is associated with earlier onset among co-affected schizophrenia sib-pairs with the same familial predisposition. METHOD:A total of 1297 patients with schizophrenia from 630 famil...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000203
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005152
更新日期:2021-01-14 00:00:00
abstract:BACKGROUND:Subthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression. The current study had two aims: (1) to determine whether an internet-based ...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291707000542
更新日期:2007-12-01 00:00:00
abstract::The expressed emotion (EE) measure is a robust predictor of relapse in schizophrenia. At least twelve studies from a range of cultures have now shown this, although the authors of one maintain their findings are the result of confounding factors. A thirteenth study which failed to demonstrate a predictive effect was s...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291700009831
更新日期:1988-11-01 00:00:00
abstract::The examination of moment-to-moment, 'micro-level' patterns of experience and behaviour using experience sampling methodology has contributed to our understanding of the 'macro-level' development of full-blown symptoms and disorders. This paper argues that the micro-level perspective can be used to identify the smalle...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291713001979
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Interest in the mental health of women deployed to modern military campaigns is increasing, although research examining gender differences is limited. Little is known about experiences women have had on these deployments, or whether men and women respond differently to combat exposure. METHOD:The current st...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171100290X
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007193
更新日期:1999-01-01 00:00:00