Abstract:
BACKGROUND:The coronavirus [coronavirus disease 2019 (COVID-19)] pandemic has introduced extraordinary life changes and stress, particularly in adolescents and young adults. Initial reports suggest that depression and anxiety are elevated during COVID-19, but no prior study has explored changes at the within-person level. The current study explored changes in depression and anxiety symptoms from before the pandemic to soon after it first peaked in Spring 2020 in a sample of adolescents and young adults (N = 451) living in Long Island, New York, an early epicenter of COVID-19 in the U.S. METHODS:Depression (Children's Depression Inventory) and anxiety symptoms (Screen for Child Anxiety Related Symptoms) were assessed between December 2014 and July 2019, and, along with COVID-19 experiences, symptoms were re-assessed between March 27th and May 15th, 2020. RESULTS:Across participants and independent of age, there were increased generalized anxiety and social anxiety symptoms. In females, there were also increased depression and panic/somatic symptoms. Multivariable linear regression indicated that greater COVID-19 school concerns were uniquely associated with increased depression symptoms. Greater COVID-19 home confinement concerns were uniquely associated with increased generalized anxiety symptoms, and decreased social anxiety symptoms, respectively. CONCLUSIONS:Adolescents and young adults at an early epicenter of the COVID-19 pandemic in the U.S. experienced increased depression and anxiety symptoms, particularly amongst females. School and home confinement concerns related to the pandemic were independently associated with changes in symptoms. Overall, this report suggests that the COVID-19 pandemic is having multifarious adverse effects on the mental health of youth.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Hawes MT,Szenczy AK,Klein DN,Hajcak G,Nelson BDdoi
10.1017/S0033291720005358subject
Has Abstractpub_date
2021-01-13 00:00:00pages
1-9eissn
0033-2917issn
1469-8978pii
S0033291720005358pub_type
杂志文章abstract:BACKGROUND:Several conceptual models have been considered for the assessment of personality pathology in DSM-5. This study sought to extend our previous findings to compare the long-term predictive validity of three such models: the five-factor model (FFM), the schedule for nonadaptive and adaptive personality (SNAP), ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002601
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Although depression and mania are often assumed to be polar opposites, studies have shown that, in patients with bipolar disorder, they are weakly positively correlated and vary somewhat independently over time. Thus, when investigating relationships between specific psychological processes and specific symp...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712002711
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Prevalence of childhood anxiety disorders at specific ages and genetic etiological influences on anxiety disorders in young children have been little studied. The present study reports prevalence estimates in a community sample of 6-year-old twins, and patterns of genetic and environmental influences on thes...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291705006537
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the original atypical antipsychotic, clozapine. Its clinical efficacy has already been demonstrated at multiple fixed doses (150-750 mg/day) and has been suggested to be comparable with haloperidol (1...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1017/s0033291799001476
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291704003551
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:The output of many healthy physiological systems displays fractal fluctuations with self-similar temporal structures. Altered fractal patterns are associated with pathological conditions. There is evidence that patients with bipolar disorder have altered daily behaviors. METHODS:To test whether fractal patt...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000331
更新日期:2020-04-01 00:00:00
abstract::One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700018912
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711000511
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:The treatment of deliberate self-harm (parasuicide) remains limited in efficacy. Despite a range of psychosocial, educational and pharmacological interventions only one approach, dialectical behaviour therapy, a form of cognitive-behaviour therapy (CBT), has been shown to reduce repeat episodes, but this is ...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s003329179800765x
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Advanced paternal age is associated with increased risk of schizophrenia. This study aimed to explore whether older paternal age is associated with earlier onset among co-affected schizophrenia sib-pairs with the same familial predisposition. METHOD:A total of 1297 patients with schizophrenia from 630 famil...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000203
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Childhood early life stress (ELS) increases risk of adulthood major depressive disorder (MDD) and is associated with altered brain structure and function. It is unclear whether specific ELSs affect depression risk, cognitive function and brain structure. METHOD:This cross-sectional study included 64 antidep...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716002403
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Almost nothing is known about the potential negative effects of Internet-based psychological treatments for depression. This study aims at investigating deterioration and its moderators within randomized trials on Internet-based guided self-help for adult depression, using an individual patient data meta-ana...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291716001562
更新日期:2016-10-01 00:00:00
abstract::Inhibition of central dopamine functions appears to be a common basic property of antipsychotic drugs. The mesolimbic and nigrostriatal portions of the dopaminergic system are probably the main targets of these drugs for the mental and the extrapyramidal actions respectively. Dopaminergic hyperfunction, induced by amp...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170000622x
更新日期:1977-11-01 00:00:00
abstract::Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700030373
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:It has been suggested that individual differences in temperament could be involved in the (non-)response to antidepressant (AD) treatment. However, how neurobiological processes such as brain glucose metabolism may relate to personality features in the treatment-resistant depressed (TRD) state remains largel...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005425
更新日期:2021-01-28 00:00:00
abstract::The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700024867
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Executive impairments have been reported in affective illness, but the influence of attention on executive performance has not been fully considered. The purpose of this study was to investigate whether executive impairments in affective illness were independent of attention impairments, and whether independ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707000712
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes. METHOD:Family practice attendees were recruited between April 2003 and February 2005 and followed over 24 months in the UK, Spain...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710002400
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Depression increases the risk of subsequent vascular events in both cardiac and non-cardiac patients. Atherosclerosis, the underlying process leading to vascular events, has been associated with depression. This association, however, may be confounded by the somatic-affective symptoms being a consequence of ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710002151
更新日期:2011-07-01 00:00:00
abstract::Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032748
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Capturing service users' perspectives can highlight additional and different concerns to those of clinicians, but there are no up to date, self-report psychometrically sound measures of side effects of antipsychotic medications. Aim To develop a psychometrically sound measure to identify antipsychotic side e...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000903
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The aims of this study were to examine the associations between exposure to unemployment following school leaving and rates of psychiatric disorder using data gathered on a birth cohort of New Zealand young people studied up to the age of 18. METHODS:At age 18 cohort members were assessed on: (a) duration o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004412
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:This study examined two competing hypotheses concerning the association between diabetes and treatment for depression: (1) the detection/ascertainment bias hypothesis suggesting that those with diabetes are more likely to be diagnosed with and treated for depression because of increased medical attention and...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001566
更新日期:2014-04-01 00:00:00
abstract::The Committee on Chronotherapeutics, delegated by the International Society for Affective Disorders (ISAD), makes the following recommendations after reviewing the evidence as of November 2004. (1) Wake therapy is the most rapid antidepressant available today: approximately 60% of patients, independent of diagnostic s...
journal_title:Psychological medicine
pub_type: 社论
doi:10.1017/s003329170500437x
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Recent neurobiological models provide a possible mechanism of daily life stress directly affecting the intensity of psychotic experiences in vulnerable individuals. In order to validate such a mechanism, the impact of daily life stress on psychosis intensity was investigated in two groups at increased risk o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704004179
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Hip fracture is common in the elderly. Previous studies suggest that psychiatric illness is common and predicts poor outcome, but have methodological weaknesses. Further studies are required to address this important issue. METHODS:We prospectively recruited 731 elderly participants with hip fracture in two...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002548
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:This study examined the associations between accelerometer-derived sedentary time (ST), lower intensity physical activity (LPA), higher intensity physical activity (HPA) and the incidence of depressive symptoms over 4 years of follow-up. METHODS:We included 2082 participants from The Maastricht Study (mean ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004924
更新日期:2020-12-18 00:00:00
abstract:BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002133
更新日期:2012-06-01 00:00:00
abstract::In a prospective cohort study of consecutive primary care attenders in south London, the estimated prevalence of non-psychotic psychiatric disorder was 45.6%, using the Revised Clinical Interview Schedule (CIS-R). The estimated 12-month incidence rate was 15.7%. Extremely high stability was found in CIS-R scores over ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004023
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Victims of war captivity sometimes suffer from complex post-traumatic stress disorder (PTSD), a unique form of PTSD that entails various alterations in personality. These alterations may involve changes in attachment orientation. METHOD:The sample comprised two groups of veterans from the 1973 Yom Kippur Wa...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708002808
更新日期:2008-10-01 00:00:00