Obstetric complications, treatment response and brain morphology in adult-onset and early-onset males with schizophrenia.

abstract：BACKGROUND:To estimate the lifetime prevalence and potential determinants of psychotic experience(s) (PEs) in the general population of Qatar - a small non-war afflicted, conservative, high-income, middle-eastern country with recent rapid urbanization including an influx of migrants. METHODS:A probability-based sample...

journal_title：Psychological medicine

authors： Khaled SM,Wilkins SS,Woodruff P

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:A series of research reports has indicated that the use of substances such as cannabis, alcohol and tobacco are higher in youth at clinical high risk (CHR) of developing psychosis than in controls. Little is known about the longitudinal trajectory of substance use, and findings on the relationship between su...

journal_title：Psychological medicine

authors： Buchy L,Cadenhead KS,Cannon TD,Cornblatt BA,McGlashan TH,Perkins DO,Seidman LJ,Tsuang MT,Walker EF,Woods SW,Heinssen R,Bearden CE,Mathalon D,Addington J

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Previous studies suggest a link between parental separation or divorce and risk of depression in adolescence. There are, however, few studies that have prospectively examined the effects of timing of biological father absence on risk for depressive symptoms in adolescence while controlling for a range of con...

journal_title：Psychological medicine

authors： Culpin I,Heron J,Araya R,Melotti R,Joinson C

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The effects of antidepressants for treating depressive disorders have been overestimated because of selective publication of positive trials. Reanalyses that include unpublished trials have yielded reduced effect sizes. This in turn has led to claims that antidepressants have clinically insignificant advanta...

journal_title：Psychological medicine

authors： Cuijpers P,Turner EH,Mohr DC,Hofmann SG,Andersson G,Berking M,Coyne J

更新日期：2014-03-01 00:00:00

abstract：:One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...

journal_title：Psychological medicine

authors： Kumar R,Robson K

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Studies have suggested that patients with schizophrenia are impaired at recognizing emotions. Recently, it has been shown that the neuropeptide oxytocin can have beneficial effects on social behaviors. METHOD:To examine emotion recognition deficits in patients and see whether oxytocin could improve these de...

journal_title：Psychological medicine

authors： Averbeck BB,Bobin T,Evans S,Shergill SS

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Overall findings of our first direct interview family study of obsessive-compulsive disorder (OCD) indicated that OCD is familial. In this replication study, we carefully examined the role of informant data in ascertaining OCD in relatives. METHOD:We interviewed 112 relatives of 57 OCD patients and 115 rela...

journal_title：Psychological medicine

authors： Lipsitz JD,Mannuzza S,Chapman TF,Foa EB,Franklin ME,Goodwin RD,Fyer AJ

更新日期：2005-11-01 00:00:00

abstract：:The Eating Attitudes Test (EAT) and General Health Questionnaire (GHQ) have been validated in an unselected population of 15-year-old South London schoolgirls. Scores on the questionnaires were compared with the results of standard interview. The EAT was found to be an efficient screening instrument for abnormal eatin...

journal_title：Psychological medicine

authors： Mann AH,Wakeling A,Wood K,Monck E,Dobbs R,Szmukler G

更新日期：1983-08-01 00:00:00

abstract：:Sixty surviving patients from a community-based stroke register who had CT scan evidence of a single brain lesion and neurological signs appropriate to it were interviewed three to five years following their first-ever stroke. Mood disorder (anxiety and depression), physical disability, and intellectual impairment wer...

journal_title：Psychological medicine

authors： Sharpe M,Hawton K,House A,Molyneux A,Sandercock P,Bamford J,Warlow C

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Counselling is frequently used in the management of common mental disorders (such as anxiety and depression) in primary care. However, there are concerns over the clinical effectiveness of counselling, both in comparison with usual general practitioner care, and with other treatments such as alternative psyc...

journal_title：Psychological medicine

authors： Bower P,Rowland N,Hardy R

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Several conceptual models have been considered for the assessment of personality pathology in DSM-5. This study sought to extend our previous findings to compare the long-term predictive validity of three such models: the five-factor model (FFM), the schedule for nonadaptive and adaptive personality (SNAP), ...

journal_title：Psychological medicine

authors： Morey LC,Hopwood CJ,Markowitz JC,Gunderson JG,Grilo CM,McGlashan TH,Shea MT,Yen S,Sanislow CA,Ansell EB,Skodol AE

更新日期：2012-08-01 00:00:00

abstract：:Bilateral electrodermal orienting responses were measured to repeated auditory stimuli in schizophrenic patients and controls. In 3 studies phasic activity to moderate intensity sounds of patients on no drugs or phenothiazines was predominantly hyper- or hypo-responsive. Controls showed moderate or slow habituation. P...

journal_title：Psychological medicine

authors： Gruzelier J,Connolly J,Eves F,Hirsch S,Zaki S,Weller M,Yorkston N

更新日期：1981-02-01 00:00:00

abstract：:The theory that many diseases were produced by focal infection or chronic sepsis enjoyed a brief vogue in general medicine in the first quarter of the twentieth century. This paper explores its practical applications in psychiatry, which extended well into the 1930s. The analysis focuses particularly closely on the ac...

journal_title：Psychological medicine

authors： Scull A

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The rate of binocular rivalry has been reported to be slower in subjects with bipolar disorder than in controls when tested with drifting, vertical and horizontal gratings of high spatial frequency. METHOD:Here we assess the rate of binocular rivalry with stationary, vertical and horizontal gratings of low ...

journal_title：Psychological medicine

authors： Miller SM,Gynther BD,Heslop KR,Liu GB,Mitchell PB,Ngo TT,Pettigrew JD,Geffen LB

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Depressive symptoms above screening thresholds have been shown to predict functional decline in older adults. Less is known about the impact of subthreshold depression, and whether more symptoms confer significantly greater risk compared to fewer symptoms. METHOD:Using data from the Duke Established Populat...

journal_title：Psychological medicine

authors： Hybels CF,Pieper CF,Blazer DG

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The salience of a visual stimulus is often reduced by nearby stimuli, an effect known as surround suppression of perceived contrast, which may help in locating the borders of an object. Weaker surround suppression has been observed in schizophrenia but it is unclear whether this abnormality is present in oth...

journal_title：Psychological medicine

authors： Schallmo MP,Sponheim SR,Olman CA

更新日期：2015-12-01 00:00:00

abstract：:A Fijian community affected by a cyclone was compared with an unaffected but similar community. Two months after the cyclone both psychological and physical morbidity was 2-3 times greater in the affected community than in controls. By the third month morbidity had resolved to levels similar to those in the unaffected...

journal_title：Psychological medicine

authors： Fairley M,Langeluddecke P,Tennant C

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:There are considerable differences between and within countries in the involvement of general practitioners (GPs) in psychosocial care. This study aimed to describe the self-perceived role of GPs in 30 European countries as the first contacted professional for patients with psychosocial problems. and to exam...

journal_title：Psychological medicine

authors： Boerma WG,Verhaak PF

更新日期：1999-05-01 00:00:00

abstract：:Sixty-four children taken to court for failure to attend school were reliably classified into 4 groups, according to whether they exhibited the features of 'school refusal' and/or 'truancy'. About a fifth of them were found to exhibit 'school refusal'; a third showed 'truancy'; less than a sixth exhibited both 'school...

journal_title：Psychological medicine

authors： Berg I,Casswell G,Goodwin A,Hullin R,McGuire R,Tagg G

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. METHOD:We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (90...

journal_title：Psychological medicine

authors： Sanders AR,Martin ER,Beecham GW,Guo S,Dawood K,Rieger G,Badner JA,Gershon ES,Krishnappa RS,Kolundzija AB,Duan J,Gejman PV,Bailey JM

更新日期：2015-05-01 00:00:00

abstract：:In a 5-week study of 22 depressed patients treated with nortriptyline, significant changes in plasma levels, both elevated and reduced, were deliberately produced in the third and fourth weeks of each patient's treatment. Correlation of plasma nortriptyline levels and changes in the severity of depression, as measured...

journal_title：Psychological medicine

authors： Burrows GD,Maguire KP,Scoggins BA,Stevenson J,Davies B

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Electronic medical records (EMR) provide a unique opportunity for efficient, large-scale clinical investigation in psychiatry. However, such studies will require development of tools to define treatment outcome. METHOD:Natural language processing (NLP) was applied to classify notes from 127 504 patients wit...

journal_title：Psychological medicine

authors： Perlis RH,Iosifescu DV,Castro VM,Murphy SN,Gainer VS,Minnier J,Cai T,Goryachev S,Zeng Q,Gallagher PJ,Fava M,Weilburg JB,Churchill SE,Kohane IS,Smoller JW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Neuroimaging studies have shown variance in brain response to emotional faces predicts cognitive behavioral therapy (CBT) outcome. An important next step is to determine if individual differences in neural predictors of CBT response represent distinct patient groups. METHODS:In total, 90 patients with inter...

journal_title：Psychological medicine

authors： Klumpp H,Jimmy J,Burkhouse KL,Bhaumik R,Francis J,Craske MG,Phan KL,Ajilore O

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Expressed emotion (EE) measured from relatives and informal carers has been consistently demonstrated to be associated with clinical outcome in schizophrenic patients. There have also been published studies that have investigated EE in professional carers that have suggested that the quality of the relations...

journal_title：Psychological medicine

authors： Tattan T,Tarrier N

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...

journal_title：Psychological medicine

authors： Sutin AR,Stephan Y,Terracciano A

更新日期：2018-04-01 00:00:00

abstract：:A structured assessment instrument, the Quality of Life Interview, was used to explain the quality of life of seventy patients with chronic psychiatric illness attending a day treatment programme. The interview was found to have acceptable psychometric properties. Factors that best predicted the quality of life of the...

journal_title：Psychological medicine

authors： Levitt AJ,Hogan TP,Bucosky CM

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...

journal_title：Psychological medicine

authors： Winsper C,Zanarini M,Wolke D

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Discontinuation of antipsychotics predisposes patients with remitted/stable first-episode psychosis (FEP) to a higher risk of relapse, but it remains unclear how long discontinuation increases the relapse rate in these patients compared with maintenance. METHODS:This meta-analysis of randomized controlled t...

journal_title：Psychological medicine

authors： Kishi T,Ikuta T,Matsui Y,Inada K,Matsuda Y,Mishima K,Iwata N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of ...

journal_title：Psychological medicine

authors： Klump KL,Perkins PS,Alexandra Burt S,McGue M,Iacono WG

更新日期：2007-05-01 00:00:00

abstract：:The epidemiology of mental problems in the Gomel region in the republic of Belarus was studied in a two-stage survey of a broad based population sample (N = 1617), using the General Health Questionnaire (12-item version) and the Munich Diagnostic Checklist for DSM-III-R. The Gomel region is one of the areas that was m...

journal_title：Psychological medicine

authors： Havenaar JM,Van den Brink W,Van den Bout J,Kasyanenko AP,Poelijoe NW,Wholfarth T,Meijler-Iljina LI

更新日期：1996-07-01 00:00:00