Kraepelin revisited: a reassessment and statistical analysis of dementia praecox and manic-depressive insanity in 1908.

Abstract:

:A meta-analysis was carried out on 53 cases of dementia praecox (DP) and 134 cases of manic-depressive insanity (MDI) originally diagnosed by Kraepelin or his collaborators in Munich in 1908. The original case material was coded in terms of Present State Examination syndromes and analysed statistically for internal consistency and discrimination between the two diagnostic entities. Kraepelin's DP and MDI were found to define homogeneous groups of disorders which could be clearly distinguished from one another. A CATEGO re-classification of the cases revealed an 80.2% concordance rate between Kraepelin's diagnoses and ICD-9. Cluster analysis of the original data reproduced closely Kraepelin's dichotomous classification of the psychoses but suggested that DP was a narrower concept than schizophrenia today, while MDI was a composite group including both 'typical' manic-depressive illnesses and schizoaffective disorders.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Jablensky A,Hugler H,Von Cranach M,Kalinov K

doi

10.1017/s0033291700026337

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

843-58

issue

4

eissn

0033-2917

issn

1469-8978

journal_volume

23

pub_type

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