Childhood trauma- and cannabis-associated microstructural white matter changes in patients with psychotic disorder: a longitudinal family-based diffusion imaging study.

abstract：BACKGROUND:Meta-analyses link childhood trauma to depression, mania, anxiety disorders, and psychosis. It is unclear, however, whether these outcomes truly represent distinct disorders following childhood trauma, or that childhood trauma is associated with admixtures of affective, psychotic, anxiety and manic psychopat...

journal_title：Psychological medicine

authors： van Nierop M,Viechtbauer W,Gunther N,van Zelst C,de Graaf R,Ten Have M,van Dorsselaer S,Bak M,Genetic Risk and OUtcome of Psychosis investigators.,van Winkel R

更新日期：2015-04-01 00:00:00

abstract：:The SIDAM--a new instrument for the symptomatic diagnosis and measurement of dementia according to DSM-III-R and ICD-10--is described. It comprises a brief structured clinical interview, a range of cognitive tests (e.g. including the Mini-Mental State (Folstein et al. 1975)) which constitute a short neuropsychological...

journal_title：Psychological medicine

authors： Zaudig M,Mittelhammer J,Hiller W,Pauls A,Thora C,Morinigo A,Mombour W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Causal attributions about bodily sensations may determine help-seeking and influence patients' demands for medical treatment. The present study aimed to differentiate the causal attributions associated with health-related and non-health-related anxiety. METHODS:Anxious hypochondriacal, generally anxious, an...

journal_title：Psychological medicine

authors： MacLeod AK,Haynes C,Sensky T

更新日期：1998-01-01 00:00:00

abstract：:This study examined the relationship between personality factors and depression in subjects who may have a familial vulnerability to depression (i.e. first-degree relatives of depressed patients). Four groups comprised our study sample: relatives who had never experienced a psychiatric episode of depression; relatives...

journal_title：Psychological medicine

authors： Katz R,McGuffin P

更新日期：1987-02-01 00:00:00

abstract：:Functional and phenotypic immunological parameters were examined immediately before, after, and 30 minutes after experimentally-induced short-term positive (happiness) and negative (anxiety, depression) affective states and a neutral state, in five healthy subjects. Results indicated that all affective states induced ...

journal_title：Psychological medicine

authors： Futterman AD,Kemeny ME,Shapiro D,Polonsky W,Fahey JL

更新日期：1992-02-01 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) was studied in the Piedmont region of North Carolina. Among 2985 subjects, the lifetime and six month prevalence figures for PTSD were 1.30 and 0.44% respectively. In comparison to non-PTSD subjects, those with PTSD had significantly greater job instability, family history of psyc...

journal_title：Psychological medicine

authors： Davidson JR,Hughes D,Blazer DG,George LK

更新日期：1991-08-01 00:00:00

abstract：:In a 5-week study of 22 depressed patients treated with nortriptyline, significant changes in plasma levels, both elevated and reduced, were deliberately produced in the third and fourth weeks of each patient's treatment. Correlation of plasma nortriptyline levels and changes in the severity of depression, as measured...

journal_title：Psychological medicine

authors： Burrows GD,Maguire KP,Scoggins BA,Stevenson J,Davies B

更新日期：1977-02-01 00:00:00

abstract：:The CAMCOG, the cognitive section of the Cambridge Examination for Mental Disorders of the Elderly (CAMDEX), was administered twice to 53 patients with a clinical diagnosis ranging from no dementia to severe dementia. The stability of the total CAMCOG score was high (0.97). Patients with less than moderate dementia we...

journal_title：Psychological medicine

authors： Lindeboom J,Ter Horst R,Hooyer C,Dinkgreve M,Jonker C

更新日期：1993-02-01 00:00:00

abstract：:Quantified magnetic resonance measurements were made of superior temporal gyrus, parahippocampal gyrus, hippocampal, frontal and temporal lobe volumes and of the planar area of the thalamus and basal ganglia structures in 47 late paraphrenic patients and 33 healthy elderly controls. The late paraphrenics were divided ...

journal_title：Psychological medicine

authors： Howard R,Mellers J,Petty R,Bonner D,Menon R,Almeida O,Graves M,Renshaw C,Levy R

更新日期：1995-05-01 00:00:00

abstract：:Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...

journal_title：Psychological medicine

authors： Mindham RH,Marsden CD,Parkes JD

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Pre- and perinatal adversities may increase the risk for schizophrenia and bipolar disorder. Hypoxia-related obstetric complications (OCs) are associated with brain anatomical abnormalities in schizophrenia, but their association with brain anatomy variation in bipolar disorder is unknown. METHOD:Magnetic r...

journal_title：Psychological medicine

authors： Haukvik UK,McNeil T,Lange EH,Melle I,Dale AM,Andreassen OA,Agartz I

更新日期：2014-04-01 00:00:00

abstract：:Principal component analysis was applied to data relating to depressive experiences collected from a general population sample. The structure of depression found in the general population showed strong similarities to that found in the psychiatric population. There were, however, important differences. Four substantia...

journal_title：Psychological medicine

authors： Cooke DJ

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:The USA is currently enduring an opioid crisis. Identifying cost-effective, easy-to-implement behavioral measures that predict treatment outcomes in opioid misusers is a crucial scientific, therapeutic, and epidemiological goal. METHODS:The current study used a mixed cross-sectional and longitudinal design ...

journal_title：Psychological medicine

authors： Moeller SJ,Hanley AW,Garland EL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...

journal_title：Psychological medicine

authors： Laskemoen JF,Aas M,Vaskinn A,Berg AO,Lunding SH,Barrett EA,Melle I,Simonsen C

更新日期：2020-04-23 00:00:00

abstract：BACKGROUND:Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. METHOD:Data were analyzed from the US Nationa...

journal_title：Psychological medicine

authors： Ruscio AM,Lane M,Roy-Byrne P,Stang PE,Stein DJ,Wittchen HU,Kessler RC

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:There is uncertainty about the incidence of breakthrough psychosis in treatment adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play in this phenomenon. METHODS:In a nationwide cohort of individuals treated for schizophrenia-spectrum disorders in Finland between 1 Ja...

journal_title：Psychological medicine

authors： Rubio JM,Taipale H,Correll CU,Tanskanen A,Kane JM,Tiihonen J

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Accumulating evidence links blood pressure variability (BPV) with white matter hyperintensities (WMH) and stroke. The longitudinal association between BPV with late onset depression (LOD) and cognitive decline remains unexplored. METHODS:Prospective cohort study of 2812 participant's age ⩾65 years (median a...

journal_title：Psychological medicine

authors： Tully PJ,Debette S,Tzourio C

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Elevated levels of circulating C-reactive protein (CRP) have been associated with coronary heart disease and, in some studies, depression. Most studies have been of populations selected by age and/or gender. We investigate these associations with depression, myocardial infarction (MI), or both, in a large ge...

journal_title：Psychological medicine

authors： Bjerkeset O,Romild U,Smith GD,Hveem K

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Hip fracture is common in the elderly. Previous studies suggest that psychiatric illness is common and predicts poor outcome, but have methodological weaknesses. Further studies are required to address this important issue. METHODS:We prospectively recruited 731 elderly participants with hip fracture in two...

journal_title：Psychological medicine

authors： Holmes J,House A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...

journal_title：Psychological medicine

authors： Smith GN,Kopala LC,Lapointe JS,MacEwan GW,Altman S,Flynn SW,Schneider T,Falkai P,Honer WG

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavi...

journal_title：Psychological medicine

authors： Blonigen DM,Hicks BM,Krueger RF,Patrick CJ,Iacono WG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Clinical intuition suggests that personality disorders hinder the treatment of depression, but research findings are mixed. One reason for this might be the way in which current assessment measures conflate general aspects of personality disorders, such as overall severity, with specific aspects, such as sty...

journal_title：Psychological medicine

authors： Constantinou MP,Frueh BC,Fowler JC,Allen JG,Madan A,Oldham JM,Fonagy P

更新日期：2020-10-08 00:00:00

abstract：:Two groups of 16 subjects, 8 of each gender, were examined on two occasions, one group before and after restricted environmental stimulation with floatation, and the other group without floatation was the control group. They were examined with a tactile object discrimination task carried out with each hand separately ...

journal_title：Psychological medicine

authors： Raab J,Gruzelier J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The atypical processing of eye contact is a characteristic hallmark of autism spectrum disorder (ASD). The severity of these symptoms, however, is thought to lie on a continuum that extends into the typical population. While behavioural evidence shows that differences in social cognitive tasks in typically d...

journal_title：Psychological medicine

authors： Madipakkam AR,Rothkirch M,Dziobek I,Sterzer P

更新日期：2019-04-01 00:00:00

abstract：:Twenty schizophrenic patients with tardive dyskinesia and an equal number of matched controls were tested on a novel cognitive task. The task had two components: cued response and spatial memory. Relative to controls, the dyskinetic subjects showed a superior cued response performance but an equal spatial memory abili...

journal_title：Psychological medicine

authors： Collerton D,Fairbairn A,Britton P

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:In previous studies an association between deployment to Iraq or Afghanistan and an overall increased risk for post-traumatic stress disorder (PTSD) in UK armed forces has not been found. The lack of a deployment effect might be explained by including, in the comparison group, personnel deployed on other ope...

journal_title：Psychological medicine

authors： Jones M,Sundin J,Goodwin L,Hull L,Fear NT,Wessely S,Rona RJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:There is not yet consensus on the best diagnostic definition of mixed bipolar episodes. Many have suggested the DSM-III-R/-IV definition is too rigid. We propose alternative criteria using data from a large patient cohort. METHODS:We evaluated 237 manic in-patients using DSM-III-R criteria and the Scale for...

journal_title：Psychological medicine

authors： Cassidy F,Ahearn E,Murry E,Forest K,Carroll BJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...

journal_title：Psychological medicine

authors： Srinivasa Murthy R,Kishore Kumar KV,Chisholm D,Thomas T,Sekar K,Chandrashekari CR

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Differences between verbal and non-verbal cognitive development from childhood to adulthood may differentiate between those with and without psychotic symptoms and affective symptoms in later life. However, there has been no study exploring this in a population-based cohort. METHOD:The sample was drawn from...

journal_title：Psychological medicine

authors： Koike S,Barnett J,Jones PB,Richards M

更新日期：2018-01-01 00:00:00

abstract：:Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...

journal_title：Psychological medicine

authors： Henderson AS,Jorm AF,Korten AE,Creasey H,McCusker E,Broe GA,Longley W,Anthony JC

更新日期：1992-05-01 00:00:00