Environmental risk factors for Alzheimer's disease: their relationship to age of onset and to familial or sporadic types.

abstract：BACKGROUND:An uneven neurocognitive profile is a hallmark of autism spectrum disorder (ASD). Studies focusing on the visual memory performance in ASD have shown controversial results. We investigated visual memory and sustained attention in youths with ASD and typically developing (TD) youths. METHOD:We recruited 143 ...

journal_title：Psychological medicine

authors： Chien YL,Gau SS,Shang CY,Chiu YN,Tsai WC,Wu YY

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Difficulties in regulating emotions are linked to the core symptoms of premenstrual dysphoric disorder (PMDD). We therefore investigated the neural substrates of emotion-regulation problems in women with PMDD. METHODS:On the basis of self-evaluations over 2 months on the Daily Record of Severity of Problems...

journal_title：Psychological medicine

authors： Petersen N,Ghahremani DG,Rapkin AJ,Berman SM,Liang L,London ED

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Morphometric endophenotypes which have been proposed for psychotic disorders include lateral ventricular enlargement and hippocampal volume reductions. Genetic epidemiological studies support an overlap between schizophrenia and bipolar disorder, and COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes have been implica...

journal_title：Psychological medicine

authors： Dutt A,McDonald C,Dempster E,Prata D,Shaikh M,Williams I,Schulze K,Marshall N,Walshe M,Allin M,Collier D,Murray R,Bramon E

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Temperament and personality traits, including negative emotionality/neuroticism, may represent risk factors for eating disorders. Further, risk factors may differ by sex. We examined longitudinal temperament/personality pathways of risk for purging and binge eating in youth stratified by sex using data from ...

journal_title：Psychological medicine

authors： Brown M,Hochman A,Micali N

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:This study aimed to explore the impacts of COVID-19 outbreak on mental health status in general population in different affected areas in China. METHODS:This was a comparative study including two groups of participants: (1) general population in an online survey in Ya'an and Jingzhou cities during the COVID...

journal_title：Psychological medicine

authors： Ran MS,Gao R,Lin JX,Zhang TM,Chan SKW,Deng XP,Zhang BZ,Zhang XF,Huang GP,Pu DS,Bai JZ,Xu LX,Liu B

更新日期：2020-12-10 00:00:00

abstract：:We recently completed a case-control study of 100 literally homeless and 100 never homeless indigent schizophrenic men in New York City, in which concurrent substance abuse and antisocial personality disorder were widespread. In this paper we probe the correlates of 'pure' schizophrenia (single disorder, N = 60), schi...

journal_title：Psychological medicine

authors： Caton CL,Shrout PE,Eagle PF,Opler LA,Felix A

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Findings from family and twin studies support a genetic contribution to the development of sexual orientation in men. However, previous studies have yielded conflicting evidence for linkage to chromosome Xq28. METHOD:We conducted a genome-wide linkage scan on 409 independent pairs of homosexual brothers (90...

journal_title：Psychological medicine

authors： Sanders AR,Martin ER,Beecham GW,Guo S,Dawood K,Rieger G,Badner JA,Gershon ES,Krishnappa RS,Kolundzija AB,Duan J,Gejman PV,Bailey JM

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Preclinical and human studies suggest an association between chronic inflammation and the development of depressive behaviors. This is proposed to occur through downstream effects of inflammatory cytokines on neuroplasticity, neurogenesis and neurotransmitter function, although the neural correlates remain p...

journal_title：Psychological medicine

authors： Ironside M,Admon R,Maddox SA,Mehta M,Douglas S,Olson DP,Pizzagalli DA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Previous imaging studies have revealed that acute major depression is characterized by altered neural responses to negative emotional stimuli. Typically, responses in limbic regions such as the amygdala are increased while activity in cortical regulatory regions such as the dorsolateral prefrontal cortex (DL...

journal_title：Psychological medicine

authors： Norbury R,Selvaraj S,Taylor MJ,Harmer C,Cowen PJ

更新日期：2010-03-01 00:00:00

abstract：:To isolate determinants of any female preponderance in depressive disorder, we earlier selected a sample of young adults, then similar in terms of several potential social determinants of depression and with equivalent rates of lifetime depression. We now report a 10-year review, which initially suggested a female pre...

journal_title：Psychological medicine

authors： Wilhelm K,Parker G

更新日期：1994-02-01 00:00:00

abstract：:The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was used to assess changes in brain 5-hydroxytryptamine (5-HT) function in normal male and female subjects, following a three week period of dieting. In women, but not men, there was a marked increase in the prolactin respo...

journal_title：Psychological medicine

authors： Goodwin GM,Fairburn CG,Cowen PJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...

journal_title：Psychological medicine

authors： Kuepper R,van Os J,Lieb R,Wittchen HU,Henquet C

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:Patients with unipolar depression show impaired performance on the Tower of London planning task. Positron emission tomography, which has previously identified resting state blood flow abnormalities in depression, was used to investigate neural activity associated with performance of this task in depressed...

journal_title：Psychological medicine

authors： Elliott R,Baker SC,Rogers RD,O'Leary DA,Paykel ES,Frith CD,Dolan RJ,Sahakian BJ

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:To estimate the lifetime prevalence and potential determinants of psychotic experience(s) (PEs) in the general population of Qatar - a small non-war afflicted, conservative, high-income, middle-eastern country with recent rapid urbanization including an influx of migrants. METHODS:A probability-based sample...

journal_title：Psychological medicine

authors： Khaled SM,Wilkins SS,Woodruff P

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Executive dysfunction, distinct from other cognitive deficits in depression, has been associated with suicidal behavior. However, this dysfunction is not found consistently across samples. METHOD:Medication-free subjects with DSM-IV major depressive episode (major depressive disorder and bipolar type I diso...

journal_title：Psychological medicine

authors： Keilp JG,Gorlyn M,Russell M,Oquendo MA,Burke AK,Harkavy-Friedman J,Mann JJ

更新日期：2013-03-01 00:00:00

abstract：:The present study examined sensitivity to noise in subjects with Type A and Type B behaviour patterns as a function of the type of task being performed. Twenty Type A and 20 Type B subjects, selected by means of Bortner's scale (French version), were exposed to steadily increasing noise levels (68-110 dBA) while perfo...

journal_title：Psychological medicine

authors： Moch A

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Several lines of evidence indicate a role of the brain-derived neurotrophic factor (BDNF) in the modulation of eating behaviour. Therefore, alterations in the physiology of this neurotrophin may be involved in the pathogenesis of eating disorders. In the present study, we investigated serum levels of BDNF in...

journal_title：Psychological medicine

authors： Monteleone P,Fabrazzo M,Martiadis V,Serritella C,Pannuto M,Maj M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Previous studies have highlighted the role of the brain reward and cognitive control systems in the etiology of anorexia nervosa (AN). In an attempt to disentangle the relative contribution of these systems to the disorder, we used functional magnetic resonance imaging (fMRI) to investigate hemodynamic respo...

journal_title：Psychological medicine

authors： Boehm I,King JA,Bernardoni F,Geisler D,Seidel M,Ritschel F,Goschke T,Haynes JD,Roessner V,Ehrlich S

更新日期：2018-04-01 00:00:00

abstract：:Although most chronically impaired psychiatric patients now reside in community-based residential homes, a substantial number show little progress in their social rehabilitation. To establish the rehabilitative needs of this population, the current study sought to examine the social behaviour of residents of a large r...

journal_title：Psychological medicine

authors： Falloon IR,Marshall GN

更新日期：1983-05-01 00:00:00

abstract：:This paper analyses patterns of episodes of anxiety and depression as recorded by 22 general practices which took part in the Second National Morbidity Survey (RCGP, 1980). The data comprise 6 years' records. Simple Markov chains are fitted to each age-group of men and women, and the inter-practice variation in the re...

journal_title：Psychological medicine

authors： Dunn G

更新日期：1983-11-01 00:00:00

abstract：:The parental representations of male-to-female and female-to-male transsexuals were rated using the EMBU inventory. Scores on the measure were compared against ratings returned by controls of similar biological sex, matched on age, educational level and number of female siblings in an ANCOVA design. In line with previ...

journal_title：Psychological medicine

authors： Cohen-Kettenis PT,Arrindell WA

更新日期：1990-08-01 00:00:00

abstract：:The persistence of psychosis at a high and relatively constant prevalence in the various populations of the world is rendered difficult to explain by the absence of identified environmental precipitants and by reduced fertility of affected individuals. The problem is not confined to schizophrenia but applies also to a...

journal_title：Psychological medicine

authors： Crow TJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:We investigated whether schizophrenic subjects are impaired in non-routine behaviour because of the dysfunction of a general executive component labelled, in neuropsychological terms, the supervisory system. METHODS:A specific verbal sequencing test was designed for this purpose. Subjects had to perform seq...

journal_title：Psychological medicine

authors： Robert PH,Migneco V,Chaix I,Berthet L,Kazes M,Danion JM,Baudu C,Darcourt G

更新日期：1997-11-01 00:00:00

abstract：:It has been proposed that a high level of agreement between informants' reports about events and happenings ('objective' data) is a sound basis for establishing (a) the validity of the measure which is based on the reports, and (b) the nature of objective reality. In this paper it is argued that such agreement may not...

journal_title：Psychological medicine

authors： Platt S

更新日期：1980-08-01 00:00:00

abstract：:The Premenstrual Syndrome (PMS) remains a controversial issue. As a clinical concept it is surrounded by confusion. Attempts to establish a consensus definition have resulted in the majority of women seeking help for such problems excluded from the diagnosis. Furthermore, there is no consensus about how such problems ...

journal_title：Psychological medicine

authors： Bancroft J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Patients treated in primary care settings report better mental outcomes when they agree with practitioners about the nature of their core presenting problems. However, no study has examined the impact of staff-patient agreement on treatment outcomes in specialist mental health services. We investigated wheth...

journal_title：Psychological medicine

authors： Lasalvia A,Bonetto C,Tansella M,Stefani B,Ruggeri M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Empirical data on the impact of personality pathology on acute treatment outcome for depression are mixed, in part because of challenges posed by assessing trait-like personality patterns while patients are in an active mood episode. To our knowledge, no previous study has examined the effect of personality ...

journal_title：Psychological medicine

authors： Cyranowski JM,Frank E,Winter E,Rucci P,Novick D,Pilkonis P,Fagiolini A,Swartz HA,Houck P,Kupfer DJ

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:A randomized trial of a primary care-based intervention to prevent depression relapse resulted in improved adherence to long-term antidepressant medication and depression outcomes. We evaluated the effects of this intervention on behavioural processes and identified process predictors of improved depressive ...

journal_title：Psychological medicine

authors： Ludman E,Katon W,Bush T,Rutter C,Lin E,Simon G,Von Korff M,Walker E

更新日期：2003-08-01 00:00:00

abstract：:Lockdowns to control the spread of the coronavirus disease 2019 (COVID-19) have had profound effects on everyday life worldwide, but their effect on mental health remains unclear because available meta-analyses and reviews rely mostly on cross-sectional studies. We conducted a rapid review and meta-analysis of longitu...

journal_title：Psychological medicine

authors： Prati G,Mancini AD

更新日期：2021-01-13 00:00:00

abstract：:The value of services for those with the 'At Risk Mental State for Psychosis' (ARMS) continues to be disputed. ARMS services have provided a valuable stimulus to academic research into the transition into psychosis. Furthermore, there is currently a welcome trend to transform such clinics into youth mental health serv...

journal_title：Psychological medicine

authors： Murray RM,David AS,Ajnakina O

更新日期：2020-09-07 00:00:00