Abstract:
:We recently completed a case-control study of 100 literally homeless and 100 never homeless indigent schizophrenic men in New York City, in which concurrent substance abuse and antisocial personality disorder were widespread. In this paper we probe the correlates of 'pure' schizophrenia (single disorder, N = 60), schizophrenia and substance abuse (double disorder, N = 89), and schizophrenia, substance abuse, and antisocial personality disorder (triple disorder, N = 50), across the homeless/never homeless distinction. Subjects were recruited from a homeless shelter and mental health service programmes in Upper Manhattan. Psychologist and social worker interviewers administered the Structured Clinical Interview for DSM-III-R, I, and II and other structured instruments to explore social, family and illness history, the current illness, and aspects of treatment and family support. Codisorder subjects emerged from more disadvantaged family backgrounds, experienced greater school difficulties, began drug use in early adolescence, were more prone to hyperactivity in childhood, and were more likely to have spent time in jail. While codisorder groups did not differ on key aspects of schizophrenia, the triple disorder group was found to suffer from a more severe form of substance abuse than double disorder subjects, associated with an earlier age of onset and abuse of a wider array of substances. The widespread prevalence of codisorders among indigent schizophrenic men has major significance for clinical psychiatry. Study of the correlates of codisorders has revealed important differences in social, family, and illness history which may guide the development of more effective treatments and improved service delivery.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Caton CL,Shrout PE,Eagle PF,Opler LA,Felix Adoi
10.1017/s0033291700027835subject
Has Abstractpub_date
1994-08-01 00:00:00pages
681-8issue
3eissn
0033-2917issn
1469-8978journal_volume
24pub_type
杂志文章abstract:BACKGROUND:Aggressive behaviour is increased among those with schizophrenia but less is known about those with affective psychoses. Similarly, little is known about aggressive behaviour occurring at the onset of illness. METHOD:The main reasons for presentation to services were examined among those recruited to a UK-b...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706008920
更新日期:2007-04-01 00:00:00
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doi:10.1017/S0033291714002797
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doi:10.1017/S0033291719001028
更新日期:2020-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0033291700008345
更新日期:1988-08-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710002461
更新日期:2011-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0033291700034735
更新日期:1996-03-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S0033291713002791
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...
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doi:10.1017/S0033291711000511
更新日期:2011-10-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799008545
更新日期:1999-07-01 00:00:00
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doi:10.1017/s0033291700025514
更新日期:1993-08-01 00:00:00
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doi:10.1017/s0033291700041246
更新日期:1981-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291718001320
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Aberrant emotional biases have been reported in bipolar disorder (BD), but results are inconsistent. Despite the clinical relevance of chronic mood variability in BD, there is no previous research investigating how the extent of symptom fluctuations in bipolar disorder might relate to emotional biases. This ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171600180X
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Most research on the prevalence, distribution, and psychiatric comorbidity of intellectual disability (ID) relies on clinical samples, limiting the generalizability and utility of ID assessment in a legal context. This study assessed ID prevalence in a population-representative sample of US adolescents and e...
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pub_type: 杂志文章
doi:10.1017/S0033291718001605
更新日期:2019-04-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291705005416
更新日期:2005-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S0033291712000980
更新日期:2013-02-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711001413
更新日期:2012-02-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700050960
更新日期:1983-05-01 00:00:00
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journal_title:Psychological medicine
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doi:10.1017/S003329172000183X
更新日期:2020-07-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001439
更新日期:2015-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S0033291709005650
更新日期:2009-10-01 00:00:00
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doi:10.1017/s0033291700018298
更新日期:1976-11-01 00:00:00
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doi:10.1017/S0033291707000712
更新日期:2007-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170000622x
更新日期:1977-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001818
更新日期:2020-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S0033291712002711
更新日期:2013-09-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002380
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this study are to investigate...
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pub_type: 杂志文章
doi:10.1017/S0033291715000215
更新日期:2015-07-01 00:00:00
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doi:10.1017/S0033291715002627
更新日期:2016-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-05-01 00:00:00