Abstract:
BACKGROUND:The relationship between recurrent major depression (MD) in women and suicidality is complex. We investigated the extent to which patients who suffered with various forms of suicidal symptomatology can be distinguished from those subjects without such symptoms. METHOD:We examined the clinical features of the worst episode in 1970 Han Chinese women with recurrent DSM-IV MD between the ages of 30 and 60 years from across China. Student's t tests, and logistic and multiple logistic regression models were used to determine the association between suicidality and other clinical features of MD. RESULTS:Suicidal symptomatology is significantly associated with a more severe form of MD, as indexed by both the number of episodes and number of MD symptoms. Patients reporting suicidal thoughts, plans or attempts experienced a significantly greater number of stressful life events. The depressive symptom most strongly associated with lifetime suicide attempt was feelings of worthlessness (odds ratio 4.25, 95% confidence interval 2.9-6.3). Excessive guilt, diminished concentration and impaired decision-making were also significantly associated with a suicide attempt. CONCLUSIONS:This study contributes to the existing literature on risk factors for suicidal symptomatology in depressed women. Identifying specific depressive symptoms and co-morbid psychiatric disorders may help improve the clinical assessment of suicide risk in depressed patients. These findings could be helpful in identifying those who need more intense treatment strategies in order to prevent suicide.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Bi B,Xiao X,Zhang H,Gao J,Tao M,Niu H,Wang Y,Wang Q,Chen C,Sun N,Li K,Fu J,Gan Z,Sang W,Zhang G,Yang L,Tian T,Li Q,Yang Q,Sun L,Li Y,Rong H,Guan C,Zhao X,Ye D,Zhang Y,Ma Z,Li H,He K,Chen J,Caidoi
10.1017/S003329171200058Xsubject
Has Abstractpub_date
2012-12-01 00:00:00pages
2591-8issue
12eissn
0033-2917issn
1469-8978pii
S003329171200058Xjournal_volume
42pub_type
杂志文章abstract::Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700033171
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doi:10.1017/s0033291700001938
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doi:10.1017/S0033291705006173
更新日期:2005-12-01 00:00:00
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更新日期:2015-07-01 00:00:00
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pub_type: 杂志文章,meta分析
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