Abstract:
:The diversity of research methods applied to psychiatric disorders results in a confusing plethora of causal claims. To help make sense of these claims, the interventionist model (IM) of causality has several attractive features. First, it connects causation with the practical interests of psychiatry, defining causation in terms of 'what would happen under interventions', a question of key interest to those of us whose interest is ultimately in intervening to prevent and treat illness. Second, it distinguishes between predictive-correlative and true causal relationships, an essential issue cutting across many areas in psychiatric research. Third, the IM is non-reductive and agnostic to issues of mind-body problem. Fourth, the IM model cleanly separates issues of causation from questions about the underlying mechanism. Clarifying causal influences can usefully structure the search for underlying mechanisms. Fifth, it provides a sorely needed conceptual rigor to multi-level modeling, thereby avoiding a return to uncritical holistic approaches that 'everything is relevant' to psychiatric illness. Sixth, the IM provides a clear way to judge both the generality and depth of explanations. In conclusion, the IM can provide a single, clear empirical framework for the evaluation of all causal claims of relevance to psychiatry and presents psychiatry with a method of avoiding the sterile metaphysical arguments about mind and brain which have preoccupied our field but yielded little of practical benefit.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Kendler KS,Campbell Jdoi
10.1017/S0033291708004467subject
Has Abstractpub_date
2009-06-01 00:00:00pages
881-7issue
6eissn
0033-2917issn
1469-8978pii
S0033291708004467journal_volume
39pub_type
社论,评审abstract:BACKGROUND:Negative associations between religion and suicide, in individuals and countries, may be mediated by the degree to which suicide is tolerated. METHODS:Linear regression was used to examine ecological associations between suicide tolerance, religion and suicide rates in 19 Western countries in 1989/90. Logis...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797005357
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Most evidence in the UK on the effectiveness of brief therapy for depression concerns cognitive behaviour therapy (CBT). In a trial published in 2000, we showed that non-directive counselling and CBT were equally effective in general practice for patients with depression and mixed anxiety and depression. Our...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291713002377
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk mental state (ARMS). We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had jus...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710000280
更新日期:2010-12-01 00:00:00
abstract::In a retrospective case note study, 73 young females with anorexia nervosa were compared with 88 young females with affective psychosis. These groups of patients did not differ in terms of place of residence, birth order or social class. They differed very significantly, however, in terms of age at onset of symptoms, ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700013295
更新日期:1990-02-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006089
更新日期:1998-01-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718001630
更新日期:2019-04-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710001431
更新日期:2011-04-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170001254x
更新日期:1989-05-01 00:00:00
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journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
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更新日期:1998-09-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291706008944
更新日期:2007-03-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700035698
更新日期:1996-05-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000830
更新日期:2016-07-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003476
更新日期:2001-04-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710002400
更新日期:2011-08-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718000041
更新日期:2018-10-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002902
更新日期:2018-06-01 00:00:00
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doi:10.1017/S0033291717002161
更新日期:2018-04-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710000887
更新日期:2011-02-01 00:00:00
abstract::Galvanized with the availability of sophisticated statistical techniques and large datasets, network medicine has emerged as an active area of investigation. Following this trend, network methods have been utilized to understand the interplay between symptoms of mental disorders. This realistic approach that may provi...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291717001350
更新日期:2017-12-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000106
更新日期:2016-05-01 00:00:00
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更新日期:2005-12-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-02-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700029275
更新日期:1977-05-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700037521
更新日期:1995-09-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700027938
更新日期:1994-08-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708002894
更新日期:2008-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716002282
更新日期:2016-12-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000148
更新日期:2020-04-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718001976
更新日期:2019-07-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,多中心研究
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更新日期:2001-04-01 00:00:00