Discriminating bipolar depression from major depressive disorder with polygenic risk scores.

abstract：BACKGROUND:Social media platforms have long been recognised as major disseminators of health misinformation. Many previous studies have found a negative association between health-protective behaviours and belief in the specific form of misinformation popularly known as 'conspiracy theory'. Concerns have arisen regardi...

journal_title：Psychological medicine

authors： Allington D,Duffy B,Wessely S,Dhavan N,Rubin J

更新日期：2020-06-09 00:00:00

abstract：:Because of the potential importance of prolonged action neuroleptics for the delivery of care to schizophrenic patients, and because of the availability of new, extensive data from clinical trials on the utility of these drugs, a workshop conference was convened by the United States National Institute of Mental Health...

journal_title：Psychological medicine

authors： Levine J,Schooler NR,Cassano GB

更新日期：1979-05-01 00:00:00

abstract：:Unnatural causes of death due to traffic accidents (TA) and suicide attempts (SA) constitute a major burden on global health, which remained stable in the last decade despite widespread efforts of prevention. Recently, latent infection with Toxoplasma gondii (T. gondii) has been suggested to be a biological risk facto...

journal_title：Psychological medicine

authors： Sutterland AL,Kuin A,Kuiper B,van Gool T,Leboyer M,Fond G,de Haan L

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Relapse is distressingly common after the first episode of psychosis, yet it is poorly understood and difficult to predict. Investigating changes in cognitive function preceding relapse may provide new insights into the underlying mechanism of relapse in psychosis. We hypothesized that relapse in fully remit...

journal_title：Psychological medicine

authors： Hui CL,Li YK,Li AW,Lee EH,Chang WC,Chan SK,Lam SY,Thornton AE,Sham P,Honer WG,Chen EY

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Individual-level measures of acculturation (e.g. age of immigration) have a complex relationship with psychiatric disorders. Fine-grained analyses that tap various acculturation dimensions and population subgroups are needed to generate hypotheses regarding the mechanisms of action for the association betwee...

journal_title：Psychological medicine

authors： Fernández RL,Morcillo C,Wang S,Duarte CS,Aggarwal NK,Sánchez-Lacay JA,Blanco C

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The assessment of inter-regional functional connectivity (FC) has allowed for the description of the putative mechanism of action of treatments such as deep brain stimulation (DBS) of the nucleus accumbens in patients with obsessive-compulsive disorder (OCD). Nevertheless, the possible FC alterations of othe...

journal_title：Psychological medicine

authors： Cano M,Alonso P,Martínez-Zalacaín I,Subirà M,Real E,Segalàs C,Pujol J,Cardoner N,Menchón JM,Soriano-Mas C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Results of previous research examining long-term residual effects of marijuana use on cognition are conflicting. A major methodological limitation of prior studies is the inability to determine whether differences between users and non-users are due to differences in genetic vulnerability preceding drug use ...

journal_title：Psychological medicine

authors： Lyons MJ,Bar JL,Panizzon MS,Toomey R,Eisen S,Xian H,Tsuang MT

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic has had a range of negative social and economic effects that may contribute to a rise in mental health problems. In this observational population-based study, we examined longitudinal changes in the prevalence of mental health problems from before to during the COVID-19 crisis and ident...

journal_title：Psychological medicine

authors： Daly M,Sutin AR,Robinson E

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Gulf War veterans have a number of health complaints. We therefore decided to carry out a systematic review to identify and summarize the findings from studies that have assessed multi-symptom conditions in Gulf War veterans and in an unexposed comparison group. METHOD:Studies published between January 1990...

journal_title：Psychological medicine

authors： Thomas HV,Stimpson NJ,Weightman AL,Dunstan F,Lewis G

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met...

journal_title：Psychological medicine

authors： Stefanis NC,Henquet C,Avramopoulos D,Smyrnis N,Evdokimidis I,Myin-Germeys I,Stefanis CN,Van Os J

更新日期：2007-11-01 00:00:00

abstract：:Forty-eight couples with a presenting problem of female sexual unresponsiveness were treated in a controlled study using a balanced factorial design. The factors varied in this design were medication (testosterone or placebo), treatment frequency (weekly or monthly sessions), and the number of therapists involved (one...

journal_title：Psychological medicine

authors： Mathews A,Whitehead A,Kellett J

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physic...

journal_title：Psychological medicine

authors： Uebelacker LA,Weisberg R,Millman M,Yen S,Keller M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Abnormalities in the anterior inter-hemispheric connectivity have previously been implicated in major depressive disorder. Disruptions in fractional anisotropy in the callosum and fornix have been reported in schizophrenia and major depressive disorder. Oligodendrocyte density and overall size of the callosu...

journal_title：Psychological medicine

authors： Williams MR,Sharma P,Fung KL,Pearce RK,Hirsch SR,Maier M

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Neurocognitive functioning may be impaired in the luteal phase of the menstrual cycle due to associated changes in hypothalamic-pituitary adrenal (HPA) axis function. This study examines the relationship between changes in neurocognition and HPA axis function in different phases of the menstrual cycle. METH...

journal_title：Psychological medicine

authors： Symonds CS,Gallagher P,Thompson JM,Young AH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Death by suicide is often preceded by attempted suicide, suicidal ideation and non-suicidal self-injury. These extreme thoughts and behaviours have been considered in terms of a continuum of suicidality. Little known research, however, has considered a suicide continuum that extends beyond these extreme thou...

journal_title：Psychological medicine

authors： Butter S,Shevlin M,Murphy J

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...

journal_title：Psychological medicine

authors： Dib JE,Yaacoub HE,Ikdais WH,Atallah E,Merheb TJ,Ajaltouni J,Akkari M,Mourad M,Nasr ME,Hachem D,Kazour F,Tahan F,Haddad G,Azar J,Zoghbi M,Haddad C,Hallit S,Adams CE

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Restrictive food intake in anorexia nervosa (AN) has been related to an overactive cognitive control network inhibiting intuitive motivational responses to food stimuli. However, the influence of short-term homeostatic signaling on the neural regulation of cue-induced food craving in AN is still unclear. ME...

journal_title：Psychological medicine

authors： Stopyra MA,Friederich HC,Mönning E,Lavandier N,Bendszus M,Herzog W,Simon JJ

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Preparing for potentially threatening events in the future is essential for survival. Anticipating the future to be unpleasant is also a cognitive key feature of depression. We hypothesized that 'pessimism'-related emotion processing would characterize brain activity in major depression.MethodDuring function...

journal_title：Psychological medicine

authors： Herwig U,Brühl AB,Kaffenberger T,Baumgartner T,Boeker H,Jäncke L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Social capital has been considered aetiologically important in schizophrenia but the empirical evidence to support this hypothesis is absent. We tested whether social capital, measured at the neighbourhood level, was associated with the incidence of schizophrenia (ICD-10 F20). MethodWe administered a cross-s...

journal_title：Psychological medicine

authors： Kirkbride JB,Boydell J,Ploubidis GB,Morgan C,Dazzan P,McKenzie K,Murray RM,Jones PB

更新日期：2008-08-01 00:00:00

abstract：:One week after Sir William Gull read his seminal report on anorexia nervosa to the Clinical Society of London, a brief account was published (Anonymous, 1873). In Paris, Charles Lasègue, editor of Archives Générales de Médecine read the report and printed an immediate editorial riposte, parts of which will be quoted i...

journal_title：Psychological medicine

authors： Silverman JA

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The relationship between white-matter tracts and executive functions (EF) in attention deficit hyperactivity disorder (ADHD) has not been well studied and previous studies mainly focused on frontostriatal (FS) tracts. The authors explored the microstructural property of several fibre tracts hypothesized to b...

journal_title：Psychological medicine

authors： Chiang HL,Chen YJ,Shang CY,Tseng WY,Gau SS

更新日期：2016-04-01 00:00:00

abstract：:A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...

journal_title：Psychological medicine

authors： Hsu LK,Sobkiewicz TA

更新日期：1989-11-01 00:00:00

abstract：:Platelet MAO activity was found to be elevated in primary depressive illness, and the severity to correlate positively with MAO activity. The reactive depression subgroup's mean platelet MAO activity was not significantly different from that of the controls. The endogenous group's unipolar and bipolar subgroups had si...

journal_title：Psychological medicine

authors： Mann J

更新日期：1979-11-01 00:00:00

abstract：:A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observat...

journal_title：Psychological medicine

authors： Weller MP,Latimer-Sayer DT

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) is highly heterogeneous and can be classified as treatment-resistant depression (TRD) or antidepressant-responsive depression (non-TRD) based on patients' responses to antidepressant treatment. Methods for distinguishing between TRD and non-TRD are critical clinical concerns. ...

journal_title：Psychological medicine

authors： Jeng JS,Li CT,Lin HC,Tsai SJ,Bai YM,Su TP,Chang YW,Cheng CM

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Genetic influences contribute significantly to co-morbidity between conduct disorder and substance use disorders. Estimating the extent of overlap can assist in the development of phenotypes for genomic analyses. METHOD:Multivariate quantitative genetic analyses were conducted using data from 9577 individua...

journal_title：Psychological medicine

authors： Grant JD,Lynskey MT,Madden PA,Nelson EC,Few LR,Bucholz KK,Statham DJ,Martin NG,Heath AC,Agrawal A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...

journal_title：Psychological medicine

authors： Sutin AR,Stephan Y,Terracciano A

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability...

journal_title：Psychological medicine

authors： Pettersson E,Lichtenstein P,Larsson H,Song J,Attention Deficit\/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of

更新日期：2019-05-01 00:00:00

abstract：:A retrospective study of alcoholic psychoses is reported. The phenomena of the illnesses corresponded poorly with classical descriptions of alcoholic hallucinosis, delirium tremens and alcoholic paranoia. Alternative diagnostic approaches were tried (Catego, restrictive definition of alcoholic hallucinosis). The probl...

journal_title：Psychological medicine

authors： Cutting J

更新日期：1978-05-01 00:00:00

abstract：BACKGROUNDS:Cigarette smoking is strongly associated with major depressive disorder (MDD). However, any genetic etiology of such comorbidity and causal relations is poorly understood, especially at the genome-wide level. METHODS:In the present in silico research, we analyzed summary data from the genome-wide associati...

journal_title：Psychological medicine

authors： Yao Y,Xu Y,Cai Z,Liu Q,Ma Y,Li AN,Payne TJ,Li MD

更新日期：2020-04-06 00:00:00