Antidepressant-resistant depression is characterized by reduced short- and long-interval cortical inhibition.

abstract：BACKGROUND:Studies evaluating depression's role in lung cancer risk revealed contradictory findings, partly because of the small number of cases, short follow-up periods, and failure to account for key covariates including smoking exposure. We investigated the association of depressive symptoms with lung cancer risk in...

journal_title：Psychological medicine

authors： Trudel-Fitzgerald C,Zevon ES,Kawachi I,Tucker-Seeley RD,Kubzansky LD

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Most evidence in the UK on the effectiveness of brief therapy for depression concerns cognitive behaviour therapy (CBT). In a trial published in 2000, we showed that non-directive counselling and CBT were equally effective in general practice for patients with depression and mixed anxiety and depression. Our...

journal_title：Psychological medicine

authors： King M,Marston L,Bower P

更新日期：2014-07-01 00:00:00

abstract：:The blood counts of 80 patients with depression were examined (50 unipolar, 30 bipolar). Many had reduced numbers of circulating lymphocytes. This abnormality was more common in the unipolar group (52%) than in the bipolar group (27%). When those patients with an abnormal dexamethasone suppression test response in bot...

journal_title：Psychological medicine

authors： Murphy D,Gardner R,Greden JF,Carroll BJ

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Most studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability...

journal_title：Psychological medicine

authors： Pettersson E,Lichtenstein P,Larsson H,Song J,Attention Deficit\/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a possible alternative to electroconvulsive therapy for the treatment of selected patients with depression, bipolar affective disorder and schizophrenia. The aim of this study was to evaluate the evidence for the effectiveness of rTMS...

journal_title：Psychological medicine

authors： McNamara B,Ray JL,Arthurs OJ,Boniface S

更新日期：2001-10-01 00:00:00

abstract：:We found diurnal weight gain to be abnormal among 28 institutionalized chronically psychotic patients. They were weighed daily for 15 days at 7 a.m. and 4 p.m. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and th...

journal_title：Psychological medicine

authors： Vieweg WV,Godleski LS,Mitchell M,Hundley PL,Yank GR

更新日期：1989-02-01 00:00:00

abstract：INTRODUCTION:Cognitive therapy (CT) for bipolar disorder emphasizes the monitoring and regulation of mood, thoughts and behaviour. The Sense of Hyper-Positive Self Scale (SHPSS) measures the extent to which bipolar patients value themselves and perceive themselves to possess personal attributes (e.g. dynamism, persuasi...

journal_title：Psychological medicine

authors： Lam D,Wright K,Sham P

更新日期：2005-01-01 00:00:00

abstract：:Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are post-synaptic receptors that are located in striatal and limbic areas known to be involved in cognition and mood. Consistent with this, 5-HT4 ...

journal_title：Psychological medicine

authors： Murphy SE,de Cates AN,Gillespie AL,Godlewska BR,Scaife JC,Wright LC,Cowen PJ,Harmer CJ

更新日期：2020-04-03 00:00:00

abstract：BACKGROUND:Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, and associated brain functions may be affected by trauma exposure in psychotic disorders. We aimed to identify the influence of trauma-exposure on brain activation and func...

journal_title：Psychological medicine

authors： Quidé Y,O'Reilly N,Watkeys OJ,Carr VJ,Green MJ

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Parental characteristics and practices predict borderline personality disorder (BPD) symptoms in children. However, it is difficult to disentangle whether these effects are genetically or environmentally mediated. The present study examines the contributions of genetic and environmental influences by compari...

journal_title：Psychological medicine

authors： Fatimah H,Wiernik BM,Gorey C,McGue M,Iacono WG,Bornovalova MA

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic has had a range of negative social and economic effects that may contribute to a rise in mental health problems. In this observational population-based study, we examined longitudinal changes in the prevalence of mental health problems from before to during the COVID-19 crisis and ident...

journal_title：Psychological medicine

authors： Daly M,Sutin AR,Robinson E

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:Cognitive models of obsessive-compulsive disorder (OCD) posit dysfunctional appraisal of disorder-relevant stimuli in patients, suggesting disturbances in the processes relying on amygdala-prefrontal connectivity. Recent neuroanatomical models add to the traditional view of dysfunction in corticostriatal cir...

journal_title：Psychological medicine

authors： Paul S,Beucke JC,Kaufmann C,Mersov A,Heinzel S,Kathmann N,Simon D

更新日期：2019-01-01 00:00:00

abstract：:Awareness of pulse rate was tested in 60 psychiatric out-patients with anxiety, phobic or hypochondriacal neuroses by asking them to record how fast their hearts were beating during exposure to short film sequences. Correlations between subjective and objective heart rate (ECG) were significantly higher in anxious and...

journal_title：Psychological medicine

authors： Tyrer P,Lee I,Alexander J

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Rumination is an important cognitive risk factor for onset and relapse of depression. However, no studies have employed a dimensional approach in investigating the neural correlates of rumination and the relationship with depression. METHOD:Non-clinical healthy subjects (n = 306), who completed the classica...

journal_title：Psychological medicine

authors： Wang K,Wei D,Yang J,Xie P,Hao X,Qiu J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that offspring of mothers with psychotic disorders have an almost two-fold higher mortality risk from birth until early adulthood. We investigated predictors of mortality from late adolescence until middle age in offspring of mothers with psychotic disorders. METHOD:The Helsinki Hig...

journal_title：Psychological medicine

authors： Suvisaari J,Häkkinen L,Haukka J,Lönnqvist J

更新日期：2008-08-01 00:00:00

abstract：:There are many reports which suggest that patients with effective illness (mania and/or depression) have abnormalities in the functioning of one or more neurobiological systems. At a conference convened by the Clinical Research Branch, Division of Extramural Research Programs, National Institute of Mental Health, thes...

journal_title：Psychological medicine

authors： Maas JW,Koslow SH,Davis JM,Katz MM,Mendels J,Robins E,Stokes PE,Bowden CL

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:The National Psychiatric Morbidity Survey (NPMS) programme was partly designed to monitor trends in mental disorders, including depression, with comparable data spanning 1993 to 2007. Findings already published from this programme suggest that concerns about increasing prevalence of common mental disorders (...

journal_title：Psychological medicine

authors： Spiers N,Brugha TS,Bebbington P,McManus S,Jenkins R,Meltzer H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...

journal_title：Psychological medicine

authors： Pritchard C,Amanullah S

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...

journal_title：Psychological medicine

authors： Dib JE,Yaacoub HE,Ikdais WH,Atallah E,Merheb TJ,Ajaltouni J,Akkari M,Mourad M,Nasr ME,Hachem D,Kazour F,Tahan F,Haddad G,Azar J,Zoghbi M,Haddad C,Hallit S,Adams CE

更新日期：2021-01-06 00:00:00

abstract：:Levinger & Clarke (1961) found that subjects tended to forget more word associations to emotional rather than neutral words. Kline (1981) regarded this study as providing 'irrefutable evidence for the Freudian concept of repression'. On the other hand, results from Kleinsmith & Kaplan (1964) suggested that this effect...

journal_title：Psychological medicine

authors： Bradley BP,Baddeley AD

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Factor analysis has been employed to identify latent variables that are unifying constructs and that parsimoniously describe correlations among a related group of variables. Confirmatory factor analysis is used to test hypothesized factor structures for a set of variables; it can also, as in this paper be us...

journal_title：Psychological medicine

authors： Jacob KS,Everitt BS,Patel V,Weich S,Araya R,Lewis GH

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Individual variation in the clinical course of bipolar disorder may have prognostic and therapeutic implications but is poorly reflected in current classifications. We aimed to establish a typology of the individual clinical trajectories based on detailed prospective medium-term follow-up. Method Latent clas...

journal_title：Psychological medicine

authors： Uher R,Mantere O,Suominen K,Isometsä E

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Abnormalities in the anterior inter-hemispheric connectivity have previously been implicated in major depressive disorder. Disruptions in fractional anisotropy in the callosum and fornix have been reported in schizophrenia and major depressive disorder. Oligodendrocyte density and overall size of the callosu...

journal_title：Psychological medicine

authors： Williams MR,Sharma P,Fung KL,Pearce RK,Hirsch SR,Maier M

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The effects of cognitive behavioural therapy of anxiety disorders on depression has been examined in previous meta-analyses, suggesting that these treatments have considerable effects on depression. In the current meta-analysis we examined whether the effects of treatments of anxiety disorders on depression ...

journal_title：Psychological medicine

authors： Cuijpers P,Cristea IA,Weitz E,Gentili C,Berking M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Gulf War veterans have a number of health complaints. We therefore decided to carry out a systematic review to identify and summarize the findings from studies that have assessed multi-symptom conditions in Gulf War veterans and in an unexposed comparison group. METHOD:Studies published between January 1990...

journal_title：Psychological medicine

authors： Thomas HV,Stimpson NJ,Weightman AL,Dunstan F,Lewis G

更新日期：2006-06-01 00:00:00

abstract：:Serum creatine phosphokinase (CPK) levels were compared with assaultive behaviour by 46 psychiatric patients. Significant relationships were found between CPK level and violent behaviour prior to admission and CPK level and seclusion as a danger to others while in hospital. No relationship was found between CPK level ...

journal_title：Psychological medicine

authors： Isaacs JS,Yesavage JA

更新日期：1984-02-01 00:00:00

abstract：:A retrospective study of alcoholic psychoses is reported. The phenomena of the illnesses corresponded poorly with classical descriptions of alcoholic hallucinosis, delirium tremens and alcoholic paranoia. Alternative diagnostic approaches were tried (Catego, restrictive definition of alcoholic hallucinosis). The probl...

journal_title：Psychological medicine

authors： Cutting J

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:A number of scales are used to estimate the severity of depression. However, differences between self-report and clinician rating, multi-dimensionality and different weighting of individual symptoms in summed scores may affect the validity of measurement. In this study we examined and integrated the psychome...

journal_title：Psychological medicine

authors： Uher R,Farmer A,Maier W,Rietschel M,Hauser J,Marusic A,Mors O,Elkin A,Williamson RJ,Schmael C,Henigsberg N,Perez J,Mendlewicz J,Janzing JG,Zobel A,Skibinska M,Kozel D,Stamp AS,Bajs M,Placentino A,Barreto M,McGuf

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Previous research has yielded conflicting evidence regarding the long-term cognitive outcome of depression. Some studies have found evidence for a higher incidence of subsequent cognitive impairment or dementia, while others have refuted this. METHOD:Depression, neuropsychological performance, functional ab...

journal_title：Psychological medicine

authors： Brodaty H,Luscombe G,Anstey KJ,Cramsie J,Andrews G,Peisah C

更新日期：2003-10-01 00:00:00

abstract：:This paper presents the results of a study of unemployment among British Asians living in the north of England. The sample comprises 139 employed and unemployed men. Using standardized psychological questionnaires with a semi-structured interview schedule, the psychological consequences of unemployment are examined in...

journal_title：Psychological medicine

authors： Shams M,Jackson PR

更新日期：1994-05-01 00:00:00