Abstract:
:Serum creatine phosphokinase (CPK) levels were compared with assaultive behaviour by 46 psychiatric patients. Significant relationships were found between CPK level and violent behaviour prior to admission and CPK level and seclusion as a danger to others while in hospital. No relationship was found between CPK level and assaultiveness while in hospital.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Isaacs JS,Yesavage JAdoi
10.1017/s0033291700003275subject
Has Abstractpub_date
1984-02-01 00:00:00pages
229-31issue
1eissn
0033-2917issn
1469-8978journal_volume
14pub_type
杂志文章abstract::Depression is one of the most prevalent mental illnesses worldwide and a leading cause of disability, especially in the setting of treatment resistance. In recent years, repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising alternative strategy for treatment-resistant depression and its clinic...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291715001609
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Empirical data on the impact of personality pathology on acute treatment outcome for depression are mixed, in part because of challenges posed by assessing trait-like personality patterns while patients are in an active mood episode. To our knowledge, no previous study has examined the effect of personality ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291703001661
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:A number of studies have suggested that indirect semantic priming is enhanced in thought-disordered schizophrenics. However, research on direct semantic priming has produced conflicting results. The aim of the present study was to resolve some of the ambiguities of previous findings. METHODS:For the present...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003105
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Childhood abuse is a risk factor for poorer illness course in bipolar disorder, but the reasons why are unclear. Trait-like features such as affective instability and impulsivity could be part of the explanation. We aimed to examine whether childhood abuse was associated with clinical features of bipolar dis...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002411
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Recent evidence suggests that postpartum psychiatric episodes may share similar etiological mechanisms with immune-related disorders. Pre-eclampsia is one of the most prevalent immune-related disorders of pregnancy. Multiple clinical features are shared between pre-eclampsia and postpartum psychiatric disord...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001385
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002718
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Childhood trauma is a risk factor for psychosis. Deficits in response inhibition are common to psychosis and trauma-exposed populations, and associated brain functions may be affected by trauma exposure in psychotic disorders. We aimed to identify the influence of trauma-exposure on brain activation and func...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002884
更新日期:2018-07-01 00:00:00
abstract::On the background of the recent discussion about the appropriateness of linear difference and ratio models for testing interaction effects of social support and stress, it is argued that interaction effects are basically unstable when dichotomized continuous variables are analysed. A data set with known interrelations...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700008394
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study ...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291712000244
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Studies have found associations between psychological distress (PD) and increased risk of myocardial infarction (MI). However, it is not clear whether the relationship reflects the subtle influence of pre-existing illness on both PD and MI. This study examines the association between PD and MI in a prospecti...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707000402
更新日期:2007-09-01 00:00:00
abstract::One hundred and eighteen subjects with an admission diagnosis of schizophrenia were reassessed after 12 months to establish whether hospital readmission had occurred. All subjects were rated at baseline and after 12 months on the Life Skills Profile (LSP), a 39-item measure of disability, with scores demonstrating mod...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028178
更新日期:1995-01-01 00:00:00
abstract::Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700007467
更新日期:1976-02-01 00:00:00
abstract::Comparison between general practice attenders and community subjects with emotional distress (as measured by GHQ-12) showed that women from a general practice sample reported more social problems than those from the community. In both men and women, problems with their spouse or partner were far more likely among gene...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028063
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Older adults have the lowest prevalence and incidence of major depressive disorder, although it has been hypothesized that this finding is due in part to differences in expression of psychopathology in later life. The aim of this study was to examine variation in depressive symptomatology in the general popu...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S003329171200027X
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005152
更新日期:2021-01-14 00:00:00
abstract:BACKGROUND:Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707001080
更新日期:2007-11-01 00:00:00
abstract::To investigate the relationships between cardiovascular variables (SBP, DBP, and HR) and circulating natural killer (NK) cell numbers, 70 male volunteers were subjected to a rest condition (N = 30) or a stressful laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the numb...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700036229
更新日期:1995-03-01 00:00:00
abstract::A detailed analysis of the results of a multi-centre clinical trial shows that, while the relapse rate following recovery from an operationally defined depressive illness was smaller among patients subsequently treated with either amitryptiline or lithium than with a placebo, there was no clinically significant differ...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700003068
更新日期:1984-02-01 00:00:00
abstract:BACKGROUND:Rumination is an important cognitive risk factor for onset and relapse of depression. However, no studies have employed a dimensional approach in investigating the neural correlates of rumination and the relationship with depression. METHOD:Non-clinical healthy subjects (n = 306), who completed the classica...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000938
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed. METHOD:Antecedent, concurrent and predictive markers of construct validity were examined for three models of PDs: the Five-Factor Model (FFM), the...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706009482
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Victims of war captivity sometimes suffer from complex post-traumatic stress disorder (PTSD), a unique form of PTSD that entails various alterations in personality. These alterations may involve changes in attachment orientation. METHOD:The sample comprised two groups of veterans from the 1973 Yom Kippur Wa...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708002808
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:We examined the prevalence of self-perceived respiratory symptoms (SRS) in the absence of any objective findings of respiratory pathology, and the association of such prevalence with psychological factors and healthcare use in the general population. METHODS:The study was conducted among a nationally repres...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718000582
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Empirical data regarding prevalence of sexual and physical abuse histories in Japanese patients with eating disorders is lacking, in contrast to Western countries. This study investigated the prevalence of traumatic events in Japanese patients with eating disorders, and examined the relationship between such...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799008557
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Fatigue syndromes and irritable bowel syndrome (IBS) often occur together. Explanations include being different manifestations of the same condition and simply sharing some symptoms. METHOD:A matched case-control study in UK primary care, using data collected prospectively in the General Practice Research D...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709005601
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:A combined family study and recovered study design was utilized to examine several hypothesized relationships between personality and bulimia nervosa (BN). METHODS:We studied 47 women with a lifetime history of DSM-III-R BN (31 currently ill and 16 recovered), 44 matched control women (CW) with no history o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002792
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:The methodology for measuring the needs of patients with severe mental illness is now well established through the MRC Needs for Care Assessment Schedule and its modification in the form of the Cardinal Needs Assessment. This paper reports the rationale and construction of a relatives' version of the Cardina...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329179800662x
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Chronic fatigue is a common symptom of multiple sclerosis (MS). A randomized controlled trial (RCT) showed that cognitive behavioural therapy (CBT) was more effective in reducing MS fatigue than relaxation training (RT). The aim of the current study was to analyse additional data from this trial to determine...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291711000924
更新日期:2012-01-01 00:00:00
abstract::Consciousness has evolved and is a feature of all animals with sufficiently complex nervous systems. It is, therefore, primarily a problem for biology, rather than physics. In this review, I will consider three aspects of consciousness: level of consciousness, whether we are awake or in a coma; the contents of conscio...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002204
更新日期:2019-09-04 00:00:00
abstract:BACKGROUND:Studies suggest that alcohol consumption and alcohol use disorders have distinct genetic backgrounds. METHODS:We examined whether polygenic risk scores (PRS) for consumption and problem subscales of the Alcohol Use Disorders Identification Test (AUDIT-C, AUDIT-P) in the UK Biobank (UKB; N = 121 630) correla...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719004045
更新日期:2020-01-20 00:00:00
abstract:BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720001749
更新日期:2020-06-11 00:00:00