Abstract：
BACKGROUND:Studies have found associations between psychological distress (PD) and increased risk of myocardial infarction (MI). However, it is not clear whether the relationship reflects the subtle influence of pre-existing illness on both PD and MI. This study examines the association between PD and MI in a prospective epidemiological study of 1864 middle-aged men to examine if the association is explained by existing illness. METHOD:This study was a prospective cohort study modelling the association between PD, measured using the 30-item General Health Questionnaire (GHQ) and non-fatal myocardial infarction (NFMI) and fatal/non-fatal myocardial infarction (FNFMI). The relationship was modelled in a series of logistic regression models adjusted for age, then cigarette smoking, then social position, and finally for all sociodemographic characteristics, coronary heart disease (CHD) risk factors, and baseline CHD. RESULTS:PD was associated with a 70% and 68% increased risk of NFMI and FNFMI in fully adjusted analysis. However, PD was not associated with an increased risk of NFMI and FNFMI in analyses excluding those with baseline CHD. Further, being psychologically distressed and physically ill was associated with a greater than twofold risk of NFMI and FNFMI, 2.37 (95% CI 1.33-4.20) and 2.33 (95% CI 1.32-4.12) respectively. CONCLUSIONS:This study suggests that PD is a moderator of the increased risk of MI associated with existing physical illness. PD in men who are physically ill is a marker of an underlying chronic physical illness. The prospective association of PD with MI is not independent of baseline physical illness.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Rasul F,Stansfeld SA,Smith GD,Shlomo YB,Gallacher Jdoi
10.1017/S0033291707000402subject
Has Abstractpub_date
2007-09-01 00:00:00pages
1305-13issue
9eissn
0033-2917issn
1469-8978pii
S0033291707000402journal_volume
37pub_type
杂志文章abstract：:The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only...
journal_title：Psychological medicine
pub_type： 临床试验,杂志文章
doi：10.1017/s0033291700024867
更新日期：1987-05-01 00:00:00
abstract：BACKGROUND:Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. METHODS:We investiga...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291719002587
更新日期：2020-10-01 00:00:00
abstract：:Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700030373
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND:Although numerous studies have examined the latent structure of major depression, less attention has focused on mania. This paper presents the first investigation outside the USA to evaluate the psychometric properties of the DSM-IV criterion B mania symptoms using item response theory (IRT). METHOD:Data we...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291712000980
更新日期：2013-02-01 00:00:00
abstract：:The persistence of psychosis at a high and relatively constant prevalence in the various populations of the world is rendered difficult to explain by the absence of identified environmental precipitants and by reduced fertility of affected individuals. The problem is not confined to schizophrenia but applies also to a...
journal_title：Psychological medicine
pub_type： 杂志文章,评审
doi：10.1017/s0033291700000611
更新日期：1987-11-01 00:00:00
abstract：BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291797006405
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND:The prevalence and impact of motor coordination difficulties in children with copy number variants associated with neurodevelopmental disorders (ND-CNVs) remains unknown. This study aims to advance understanding of motor coordination difficulties in children with ND-CNVs and establish relationships between i...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291719003210
更新日期：2019-11-19 00:00:00
abstract：BACKGROUND:Victims of war captivity sometimes suffer from complex post-traumatic stress disorder (PTSD), a unique form of PTSD that entails various alterations in personality. These alterations may involve changes in attachment orientation. METHOD:The sample comprised two groups of veterans from the 1973 Yom Kippur Wa...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291708002808
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291720005152
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:Depression is a challenge to diagnose reliably and the current gold standard for trials of DSM-5 has been in agreement between two or more medical specialists. Research studies aiming to objectively predict depression have typically used brain scanning. Less expensive methods from cognitive neuroscience may ...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291720003608
更新日期：2020-11-09 00:00:00
abstract：BACKGROUND:Current literature provides insufficient information on the degree of cognitive impairment during and after electroconvulsive therapy (ECT), mostly due to the fact that applied tests lacked sensitivity and flexibility. Our goal was to evaluate cognitive functioning in adult depressed patients treated with bi...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291715002287
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:We studied whether heterogeneous profiles of cognitive function are relevant to survival in patients with early Alzheimer's disease. METHODS:CAMCOG subscales of cognitive function were used as predictors of survival, together with gender in 157 consecutively referred patients with early Alzheimer's disease....
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291798007375
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Prior studies have suggested that major depressive disorder (MDD) with pre-adult onset represents a distinct subtype with greater symptom severity and higher rates of suicidal ideation. Whether these patients have poorer response to various types of antidepressant treatment than those with adult-onset MDD is...
journal_title：Psychological medicine
pub_type： 杂志文章,随机对照试验
doi：10.1017/S0033291712001742
更新日期：2013-05-01 00:00:00
abstract：:Five idiots savants whose artistic output was judged to be at art school entrance standard were matched for performance and verbal IQ with control subjects who had no special artistic talent. Each subject was given tests of reproductive skill with both concrete pictures and unfamiliar and unnameable geometric designs....
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700013003
更新日期：1987-02-01 00:00:00
abstract：:The expressed emotion (EE) measure is a robust predictor of relapse in schizophrenia. At least twelve studies from a range of cultures have now shown this, although the authors of one maintain their findings are the result of confounding factors. A thirteenth study which failed to demonstrate a predictive effect was s...
journal_title：Psychological medicine
pub_type： 杂志文章,评审
doi：10.1017/s0033291700009831
更新日期：1988-11-01 00:00:00
abstract：BACKGROUND:Previous studies of the dimensional structure of panic attack symptoms have mostly identified a respiratory and a vestibular/mixed somatic dimension. Evidence for additional dimensions such as a cardiac dimension and the allocation of several of the panic attack symptom criteria is less consistent. Clarifyin...
journal_title：Psychological medicine
pub_type： 杂志文章,多中心研究
doi：10.1017/S0033291714002803
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:A long-standing issue in the health anxiety literature is the extent to which health anxiety is a dimensional or a categorical construct. This study explores this question directly using taxometric procedures. METHOD:Seven hundred and eleven working adults completed an index of health anxiety [the Whiteley ...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291708003322
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:A combined family study and recovered study design was utilized to examine several hypothesized relationships between personality and bulimia nervosa (BN). METHODS:We studied 47 women with a lifetime history of DSM-III-R BN (31 currently ill and 16 recovered), 44 matched control women (CW) with no history o...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291799002792
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:Although the traditional view of bipolar affective disorder is that the majority of patients have full remission between episodes, recent evidence suggests that residual cognitive deficits are present. The aim of this study was to determine whether memory and executive deficits were present in a well-defined...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291799002664
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:Preclinical and human studies suggest an association between chronic inflammation and the development of depressive behaviors. This is proposed to occur through downstream effects of inflammatory cytokines on neuroplasticity, neurogenesis and neurotransmitter function, although the neural correlates remain p...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291719002940
更新日期：2020-12-01 00:00:00
abstract：:This study aimed to investigate the psychological characteristics of chronic fatigue syndrome (CFS: Holmes et al. 1988). A battery of psychometric instruments comprising the General Health Questionnaire (GHQ), the Beck Depression Inventory (BDI), the Minnesota Multiphasic Personality Inventory (MMPI) and the Lazarus W...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700020456
更新日期：1991-05-01 00:00:00
abstract：BACKGROUND:The correlates of insight in early-onset psychosis have received little previous attention. METHOD:We studied clinical correlates of insight in a sample of 110 adolescent recent-onset psychosis patients (mean age 15.53 years; psychotic symptoms present for <6 months). Insight was measured with the Scale to ...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291708004868
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291711000857
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Self-harm among young adults is a common and increasing phenomenon in many parts of the world. The long-term prognosis after self-harm at young age is inadequately known. We aimed to estimate the risk of mental illness and suicide in adult life after self-harm in young adulthood and to identify prognostic fa...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291716002282
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Different versions of the General Health Questionnaire (GHQ), including the GHQ-12 and GHQ-28 have been subjected to factor analysis in a variety of countries. The World Health Organization study of psychological disorders in general health care offered the opportunity to investigate the factor structure of ...
journal_title：Psychological medicine
pub_type： 杂志文章,多中心研究
doi：10.1017/s0033291799002287
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:There is increasing recognition that, in addition to negative psychological consequences of trauma such as post-traumatic stress disorder (PTSD), some individuals may develop post-traumatic growth (PTG) following such experiences. To date, however, data regarding the prevalence, correlates and functional sig...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/S0033291714001202
更新日期：2015-01-01 00:00:00
abstract：:There are many reports which suggest that patients with effective illness (mania and/or depression) have abnormalities in the functioning of one or more neurobiological systems. At a conference convened by the Clinical Research Branch, Division of Extramural Research Programs, National Institute of Mental Health, thes...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700055057
更新日期：1980-11-01 00:00:00
abstract：:Sixty surviving patients from a community-based stroke register who had CT scan evidence of a single brain lesion and neurological signs appropriate to it were interviewed three to five years following their first-ever stroke. Mood disorder (anxiety and depression), physical disability, and intellectual impairment wer...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700036503
更新日期：1990-11-01 00:00:00
abstract：:The Social Behaviour Schedule (SBS) was examined as a measure of disability in a series of 66 chronic psychiatric patients, who were also assessed using the Social Role Performance Schedule (SRP) and the ninth edition of the Present State Examination (PSE). All three schedules have been used in previous studies in the...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700025046
更新日期：1987-05-01 00:00:00
abstract：:A community survey of psychiatric disorder carried out in South London enabled the authors to investigate the 'vulnerability model' proposed by Brown & Harris (1978). In the current study none of the 'vulnerability factors' proposed by Brown & Harris fulfilled the requirements of the model. It was, however, found that...
journal_title：Psychological medicine
pub_type： 杂志文章
doi：10.1017/s0033291700003603
更新日期：1984-05-01 00:00:00
