Lymphocyte numbers in endogenous depression.

Abstract:

:The blood counts of 80 patients with depression were examined (50 unipolar, 30 bipolar). Many had reduced numbers of circulating lymphocytes. This abnormality was more common in the unipolar group (52%) than in the bipolar group (27%). When those patients with an abnormal dexamethasone suppression test response in both groups were compared, the relative and absolute lymphocyte counts were significantly lower in unipolars. Although cortisol hypersecretion may reduce lymphocyte numbers it is not yet clear whether the findings can be satisfactorily explained in this way.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Murphy D,Gardner R,Greden JF,Carroll BJ

doi

10.1017/s0033291700024934

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

381-5

issue

2

eissn

0033-2917

issn

1469-8978

journal_volume

17

pub_type

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