Abstract:
BACKGROUND:The diagnosis of bipolar disorder in pre-pubertal populations remains difficult and often controversial. Consequently, the clinical and neuropsychological characteristics of mania in the child and adolescent years remain poorly defined. This review provides a clinical account of childhood and adolescent bipolar disorder and compares the neuropsychology and neuroanatomy of young BPD patients compared with adult BPD and childhood syndromes of attention deficit hyperactivity disorder (ADHD) and conduct disorder (CD). METHOD:Literature review based on Pubmed searches. RESULTS:Early- and adult-onset mania and BPD may share a common pattern of neurobiological characteristics despite developmental variations in the clinical presentation. In contrast, important distinctions are apparent between the child-onset syndromes of BPD, ADHD and CD, specifically at the neural level. CONCLUSIONS:Disorders of affect dysregulation in childhood deserve closer neuroscientific and phenotypic scrutiny than given hitherto.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Kyte ZA,Carlson GA,Goodyer IMdoi
10.1017/S0033291706007446subject
Has Abstractpub_date
2006-09-01 00:00:00pages
1197-211issue
9eissn
0033-2917issn
1469-8978pii
S0033291706007446journal_volume
36pub_type
杂志文章,评审abstract:BACKGROUND:Cognitive-behavioral therapy (CBT) is thought to be useful for chronic pain, with the pathology of the latter being closely associated with cognitive-emotional components. However, there are few resting-state functional magnetic resonance imaging (R-fMRI) studies. We used the independent component analysis m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002598
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The outcome of schizophrenia appears to be more favourable than once thought. However, methodological issues, including the reliance on diagnosis at first presentation have limited the validity of outcome studies to date. METHOD:We conducted a first-episode follow-up study of 97 patients with DSM-IV schizop...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170800336X
更新日期:2008-08-01 00:00:00
abstract::One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700018912
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:A key challenge in trauma care is the prevention of psychopathology. However, no definitive method of identifying individuals at risk of developing psychopathology exists. The Aberdeen Trauma Screening Index (ATSI) is a brief screening tool developed for use in a clinical setting by non-mental health profess...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291702005809
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:The ability to appreciate humour is essential to successful human interactions. In this study, we hypothesized that individuals with schizophrenia would have diminished ability to recognize and appreciate humour. The relationship between humour experience and clinical symptoms, cognitive and social functioni...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002528
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000542
更新日期:2012-11-01 00:00:00
abstract::Using the 40-item Eating Attitudes Test and other self-report questions, a two-stage screening survey of 1020 (F 646, M 374) Chinese bilingual university students in Hong Kong showed that although female students were 'underweight' by Western standard, the majority of them and nearly all female students above a body m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028531
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Adverse effects of antidepressants are most common at the beginning of the treatment, but possible also later. We examined the association between antidepressant use and work-related injuries taking into account the duration of antidepressant use. METHOD:Antidepressant use and work-related injuries between ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002925
更新日期:2016-05-01 00:00:00
abstract::On the background of the recent discussion about the appropriateness of linear difference and ratio models for testing interaction effects of social support and stress, it is argued that interaction effects are basically unstable when dichotomized continuous variables are analysed. A data set with known interrelations...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700008394
更新日期:1988-08-01 00:00:00
abstract::Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700011843
更新日期:1986-11-01 00:00:00
abstract::The epidemiology of mental problems in the Gomel region in the republic of Belarus was studied in a two-stage survey of a broad based population sample (N = 1617), using the General Health Questionnaire (12-item version) and the Munich Diagnostic Checklist for DSM-III-R. The Gomel region is one of the areas that was m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700037879
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Psychiatric history, familial history of suicide attempts, and certain traumatic life events are important predictors of suicidal thoughts and behaviour. We examined the epidemiology and genetics of suicidality (i.e. reporting persistent suicidal thoughts or a plan or suicide attempt) in a large community-ba...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798006916
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:The processing of facial emotion involves a distributed network of limbic and paralimbic brain structures. Many of these regions are also implicated in the pathophysiology of mood disorders. Behavioural data indicate that depressed subjects show a state-related positive recognition bias for faces displaying ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704002557
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Women's vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This ...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291714002773
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706009159
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:It is clearly established that emotional events tend to be remembered particularly vividly. The neurobiological substrates of this phenomenon are poorly understood. Recently, the noradrenergic system has been implicated in that beta blockade has been shown to reduce significantly the delayed recall of emotio...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291799008703
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:There is substantial variability in the degree of cognitive impairment among older depressed persons. Inconsistencies in previous findings may be due to differences in clinical and demographic characteristics across study samples. We assessed the influence of unipolar depression and severity of depression on...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001736
更新日期:2014-04-01 00:00:00
abstract::One week after Sir William Gull read his seminal report on anorexia nervosa to the Clinical Society of London, a brief account was published (Anonymous, 1873). In Paris, Charles Lasègue, editor of Archives Générales de Médecine read the report and printed an immediate editorial riposte, parts of which will be quoted i...
journal_title:Psychological medicine
pub_type: 传,历史文章,杂志文章
doi:10.1017/s0033291700030245
更新日期:1992-05-01 00:00:00
abstract::Awareness of pulse rate was tested in 60 psychiatric out-patients with anxiety, phobic or hypochondriacal neuroses by asking them to record how fast their hearts were beating during exposure to short film sequences. Correlations between subjective and objective heart rate (ECG) were significantly higher in anxious and...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700039726
更新日期:1980-02-01 00:00:00
abstract:BACKGROUND:This study investigated factors contributing to suspected offending behaviour by adults with a history of learning disabilities taken into custody at a city police station. METHODS:Adults charged with offences, and/or leaving custody, during a defined period, were identified as having a possible learning di...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797004777
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:Risk factors that are associated with depression in the mother also negatively affect the child. This research sought to extend current knowledge by examining the duration and timing of maternal depression as a moderator of: (1) the impact of dependent interpersonal stress (DIS), such as partner conflict or ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712002450
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Many studies have reported an increased incidence of psychiatric disorder (particularly psychotic disorders) among first generation adult immigrants, along with an increasing risk for ethnic minorities living in low-minority concentration neighborhoods. These studies have depended mostly on European case-bas...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711000213
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Individual variation in the clinical course of bipolar disorder may have prognostic and therapeutic implications but is poorly reflected in current classifications. We aimed to establish a typology of the individual clinical trajectories based on detailed prospective medium-term follow-up. Method Latent clas...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712001523
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), com...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004316
更新日期:2020-12-02 00:00:00
abstract:BACKGROUND:Two types of mentalization-based treatment (MBT), day hospital MBT (MBT-DH) and intensive outpatient MBT (MBT-IOP), have been shown to be effective in treating patients with borderline personality disorder (BPD). This study evaluated trajectories of change in a multi-site trial of MBT-DH and MBT-IOP at 36 mo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720002123
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:Interpersonal stress generation is an important maintaining factor in major depression; however, little is known about the psychological mechanisms that undermine interpersonal functioning. This study investigated the role of deficits in person perception to this regard. METHOD:Depressed patients (n = 20) a...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714000622
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:There have been conflicting reports on time trends in urban-rural differences in the incidence of schizophrenia. This study explored the potential time trends in these differences with regard to birth cohort and age at onset. METHOD:Linking data from the Danish Civil Registration system with data from the D...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170500663X
更新日期:2006-02-01 00:00:00
abstract::We report the results of a survey of the burdens and needs for items of care of 45 supporters of long-term users of psychiatric day care facilities in Camberwell. The supporters reported high levels of disturbed behaviour and low levels of self-care skills in the attenders. They were also subject to high levels of soc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700024326
更新日期:1989-08-01 00:00:00
abstract::Primiparae were randomly assigned to two conditions of routine ultrasound examination at their first antenatal clinic visit: (a) high feedback ultrasound where the monitor screen was visible and the patient was shown the foetal size, shape and movement (N = 67); (b) low feedback ultrasound where the screen was not see...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700046717
更新日期:1982-05-01 00:00:00
abstract:BACKGROUND:Few large studies describe links between maternal mental illness and risk of major birth defect in offspring. Evidence is sparser still for how effects vary between maternal diagnoses and no previous study has assessed risk with paternal illnesses. METHOD:A population-based birth cohort was created by linki...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002280
更新日期:2008-10-01 00:00:00