Abstract:
:This study examined the relationship between personality factors and depression in subjects who may have a familial vulnerability to depression (i.e. first-degree relatives of depressed patients). Four groups comprised our study sample: relatives who had never experienced a psychiatric episode of depression; relatives who had experienced a psychiatric episode of depression but were currently well; relatives who had never experienced a psychiatric episode of depression but were currently depressed; and relatives who had experienced a past history of depression and were currently depressed. Of the four personality characteristics measured (Psychoticism, Extraversion, Neuroticism and Lie), the only significant effects between groups appeared to be attributable to Neuroticism (N). The strongest association was between current illness and N. There was also a tendency for subjects with a past history of depression to have an inflated N score. However, this appeared to be associated with the presence of current depressive symptomatology. Our findings indicate that when current symptomatology is taken into account Neuroticism does not seem to reflect the trait of liability to depression, but is strongly associated with the state of being depressed.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Katz R,McGuffin Pdoi
10.1017/s0033291700013052subject
Has Abstractpub_date
1987-02-01 00:00:00pages
155-61issue
1eissn
0033-2917issn
1469-8978journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Developmental adversities may be risk factors for adult suicidal behavior, but this relationship has rarely been studied prospectively. The present study examined the association between childhood adversities and new onset suicidal ideation and attempts in an adult population-based sample. METHOD:The study ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706008646
更新日期:2006-12-01 00:00:00
abstract::This is a study of the criterion validity of a newly developed computerized assessment (PROQSY) of minor psychological morbidity based on the Clinical Interview Schedule, employing a single GP's assessments as criterion measures of such morbidity and Relative Operating Characteristic (ROC) analysis. Two-stage screenin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700011193
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:As children with attention-deficit/hyperactivity disorder (ADHD) usually show psychopathological signs beyond their core symptoms (e.g. elevated scores of the dysregulation profile (DP) in 30-40%), treatments with a broader approach to self-regulation skills may be supportive. Neurofeedback (NF) may reflect ...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291718004130
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Cannabis use is associated with altered neurocognitive functioning in severe mental disorders, but data are still inconclusive and there are no studies of bipolar disorder. The aim of this study was to investigate the association between cannabis use and neurocognition in bipolar disorder compared with schiz...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991620
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000914
更新日期:2020-04-23 00:00:00
abstract:BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002718
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:There is not yet consensus on the best diagnostic definition of mixed bipolar episodes. Many have suggested the DSM-III-R/-IV definition is too rigid. We propose alternative criteria using data from a large patient cohort. METHODS:We evaluated 237 manic in-patients using DSM-III-R criteria and the Scale for...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799001312
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:. A variety of factors are related to compliance with medication in schizophrenia, but little attention has been paid to the role of families. Carers' knowledge or expressed emotion (EE) may be related to compliance. The aim of the present study was to evaluate the relevance of these two factors, as well as ...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291702006888
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Women's vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This ...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291714002773
更新日期:2015-06-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170003289x
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:There is an emerging consensus in developmental psychopathology that irritable youth are at risk for developing internalizing problems later in life. The current study explored if irritability in youth is multifactorial and the impact of irritability dimensions on psychopathology outcomes in adulthood. METH...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002903
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720001749
更新日期:2020-06-11 00:00:00
abstract::Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700011843
更新日期:1986-11-01 00:00:00
abstract:BACKGROUND:Differences between verbal and non-verbal cognitive development from childhood to adulthood may differentiate between those with and without psychotic symptoms and affective symptoms in later life. However, there has been no study exploring this in a population-based cohort. METHOD:The sample was drawn from...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000393
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The medial forebrain bundle (MFB) is an important pathway of the reward system. Two branches have been described using diffusion magnetic resonance imaging (MRI)-based tractography: the infero-medial MFB (imMFB) and the supero-lateral MFB (slMFB). Previous studies point to white-matter microstructural altera...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714001949
更新日期:2015-03-01 00:00:00
abstract::Taxometric procedures have been used extensively to investigate whether individual differences in personality and psychopathology are latently dimensional or categorical ('taxonic'). We report the first meta-analysis of taxometric research, examining 317 findings drawn from 183 articles that employed an index of the c...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000183X
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Self-harm among young adults is a common and increasing phenomenon in many parts of the world. The long-term prognosis after self-harm at young age is inadequately known. We aimed to estimate the risk of mental illness and suicide in adult life after self-harm in young adulthood and to identify prognostic fa...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716002282
更新日期:2016-12-01 00:00:00
abstract::Potential cases of presenile dementia of the Alzheimer type (PDAT) in the Northern Health Region (estimated population aged 45-64, 655,800) were ascertained for the years 1979-86 from in-patient ICD-9 codes and other sources. An algorithm was applied to the casenote information to distinguish between Alzheimer-type an...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700025411
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Certain personality traits predispose to criminal behavior (CB). We further clarify this relationship in a Swedish national sample. METHOD:Psychological strength (PS) was assessed on a nine-point scale at personal interview in 1 653 721 Swedish men aged 18-20 years. We examined the association between PS an...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001403
更新日期:2016-01-01 00:00:00
abstract::The incidence of cavum septum pellucidum (CSP), which has been widely regarded as a developmental anomaly of little clinical importance in neuropathology, was examined in 113 patients with affective disorders (69 with bipolar disorder and 44 with major depression), 40 schizophrenic patients, and 92 control subjects by...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034838
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:The common mental disorders (CMDs) of anxiety and depression are the most common form of poor mental health in the general population. Evidence from the small number of previous cohort studies on the role of neighbourhood factors in mental health is inconclusive. We tested the hypothesis that high levels of ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713003255
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002315
更新日期:2012-06-01 00:00:00
abstract::We recently completed a case-control study of 100 literally homeless and 100 never homeless indigent schizophrenic men in New York City, in which concurrent substance abuse and antisocial personality disorder were widespread. In this paper we probe the correlates of 'pure' schizophrenia (single disorder, N = 60), schi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700027835
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:It has been suggested that individual differences in temperament could be involved in the (non-)response to antidepressant (AD) treatment. However, how neurobiological processes such as brain glucose metabolism may relate to personality features in the treatment-resistant depressed (TRD) state remains largel...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005425
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:Feedback learning is essential for behavioral development. We investigated feedback learning in relation to behavior problems after pediatric traumatic brain injury (TBI). METHOD:Children aged 6-13 years diagnosed with TBI (n = 112; 1.7 years post-injury) were compared with children with traumatic control (...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000106
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:We report the prevalence, clinical characteristics, frequency of mental health treatment, demographic correlates, frequency of co-morbid psychiatric conditions, and general health ramifications of DSM-IV blood-injection-injury phobia in the general population. METHOD:The Diagnostic Interview Schedule (versi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291798007144
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:This study seeks to clarify the contribution of temporally stable and occasion-specific genetic and environmental influences on risk for major depression (MD). METHOD:Our sample was 2153 members of female-female twin pairs from the Virginia Twin Registry. We examined four personal interview waves conducted ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000277
更新日期:2017-07-01 00:00:00
abstract::Platelet MAO activity was found to be elevated in primary depressive illness, and the severity to correlate positively with MAO activity. The reactive depression subgroup's mean platelet MAO activity was not significantly different from that of the controls. The endogenous group's unipolar and bipolar subgroups had si...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034048
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:Substantial variability in age at onset of illness and course of illness exists between patients with schizophrenia. Recent studies suggest that age at illness onset may be useful in defining biologically and clinically distinct subgroups of patients. METHODS:Two hundred and ten males with schizophrenia wer...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797006405
更新日期:1998-05-01 00:00:00
abstract::Monthly hospital admission rates (HA) for mania were classified by sex, type of admission (first, or re-admission) and by country (England and Wales or Scotland). Of the 8 classes thus created, all but one showed a statistically significant annual cycle with a peak in Summer and trough in Winter. There was no signific...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170001610x
更新日期:1978-08-01 00:00:00