Abstract:
:Potential cases of presenile dementia of the Alzheimer type (PDAT) in the Northern Health Region (estimated population aged 45-64, 655,800) were ascertained for the years 1979-86 from in-patient ICD-9 codes and other sources. An algorithm was applied to the casenote information to distinguish between Alzheimer-type and other forms of dementia. A search of the NHS central register was made to establish date and place of death. Estimates were made for patients with missing case records. The point prevalence rate for PDAT was estimated as 34.6 per 100,000 with an annual incidence of 7.2 per 100,000 in the 45-64 age range. These rates are compared with those reported in other studies. Five-year survival following diagnosis for incident cases of PDAT was 64% with a longevity quotient (LQ), the percentage of expected time actually survived, of 69%. There was no evidence of a more malignant course in PDAT when compared with survival in older patients with dementia of the Alzheimer type (DAT) in other studies. Sixty-six per cent of deaths occurred in hospital, 19% at home and 15% in residential homes.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Newens AJ,Forster DP,Kay DW,Kirkup W,Bates D,Edwardson Jdoi
10.1017/s0033291700025411subject
Has Abstractpub_date
1993-08-01 00:00:00pages
631-44issue
3eissn
0033-2917issn
1469-8978journal_volume
23pub_type
杂志文章abstract:BACKGROUND:This study examined the associations between accelerometer-derived sedentary time (ST), lower intensity physical activity (LPA), higher intensity physical activity (HPA) and the incidence of depressive symptoms over 4 years of follow-up. METHODS:We included 2082 participants from The Maastricht Study (mean ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004924
更新日期:2020-12-18 00:00:00
abstract:BACKGROUND:The base rate of transition from subthreshold psychotic experiences (the exposure) to clinical psychotic disorder (the outcome) in unselected, representative and non-help-seeking population-based samples is unknown. METHOD:A systematic review and meta-analysis was conducted of representative, longitudinal p...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S0033291711002911
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Sibling resemblance in crime may be due to genetic relatedness, shared environment, and/or the interpersonal influence of siblings on each other. This latter process can be understood as a type of 'peer effect' in that it is based on social learning between individuals occupying the same status in the social...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003724
更新日期:2020-10-21 00:00:00
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journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s003329170300816x
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Little is known about how continuation and maintenance cognitive-behavioural therapy (CBT) influences important psychological constructs that may be associated with long-term outcome of major depressive disorder. The goal of this study was to examine whether CBT would help maintain attributional style change...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291703001028
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Life events and social problems are common in primary-care attenders and contribute to the high rate of emotional distress observed in this setting but are often not disclosed during the consultation. Physicians' characteristics associated with patients' disclosure of psychosocial problems are well documente...
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pub_type: 杂志文章
doi:10.1017/s0033291798007478
更新日期:1998-11-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700057779
更新日期:1986-02-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000063X
更新日期:2020-04-06 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001439
更新日期:2015-12-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002883
更新日期:2001-01-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700017669
更新日期:1990-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/S0033291703001661
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Few population studies have investigated the functional disabilities that accompany specific psychiatric diagnoses. This study assesses the nature and strength of current and residual impairments in various functional domains of life. METHODS:Data were derived from the Netherlands Mental Health Survey and I...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799001841
更新日期:2000-05-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700004414
更新日期:1977-08-01 00:00:00
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journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002184
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:This study aimed to explore the impacts of COVID-19 outbreak on mental health status in general population in different affected areas in China. METHODS:This was a comparative study including two groups of participants: (1) general population in an online survey in Ya'an and Jingzhou cities during the COVID...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004717
更新日期:2020-12-10 00:00:00
abstract:BACKGROUND:The aims of this study were to examine the associations between exposure to unemployment following school leaving and rates of psychiatric disorder using data gathered on a birth cohort of New Zealand young people studied up to the age of 18. METHODS:At age 18 cohort members were assessed on: (a) duration o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004412
更新日期:1997-03-01 00:00:00
abstract::Serum total androgens were estimated by radioimmunoassay on blood samples of treatment-seeking homosexuals and heterosexual controls. There was no significant difference in androgen levels between the homosexual and control group, nor was there any relationship between androgen levels and response to treatment. These ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700004396
更新日期:1977-08-01 00:00:00
abstract:BACKGROUND:Older adults have the lowest prevalence and incidence of major depressive disorder, although it has been hypothesized that this finding is due in part to differences in expression of psychopathology in later life. The aim of this study was to examine variation in depressive symptomatology in the general popu...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S003329171200027X
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Aggressive behaviour is increased among those with schizophrenia but less is known about those with affective psychoses. Similarly, little is known about aggressive behaviour occurring at the onset of illness. METHOD:The main reasons for presentation to services were examined among those recruited to a UK-b...
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doi:10.1017/S0033291706008920
更新日期:2007-04-01 00:00:00
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journal_title:Psychological medicine
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doi:10.1017/s0033291700012435
更新日期:1989-05-01 00:00:00
abstract::Changes in the erythrocyte membrane cation carrier following lithium ingestion in normal human subjects were studied; ouabain sensitive potassium influx fell significantly during the lithium treated phase. Lithium was fed to rats and no change in erythrocyte Na-K ATPase was shown. These findings contrast with studies ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700029305
更新日期:1977-05-01 00:00:00
abstract::National statistics for railway fatalities in England and Wales show a reduction of train crashes and a fluctuating level of deaths, of which an increasing proportion is from suicide. A closer examination of a two-year sample from the South of England revealed a large proportion of probable suicides and a small propor...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700031469
更新日期:1985-08-01 00:00:00
abstract:BACKGROUND:Several psychological and neurobiological models imply that patients with schizophrenia (SCZ) are more inclined to utilize emotional cues as response determinants to the detriment of more task-appropriate cognitive or contextual cues. However, there is a lack of behavioural data from human clinical studies t...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713000445
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The histological basis of schizophrenia is unknown, but it appears to affect the hippocampal and neocortical cytoarchitecture. Some cytoarchitectural parameters normally differ between the two cerebral hemispheres. Moreover, schizophrenia is associated with altered structural cerebral asymmetry. However, few...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004618
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:Geographic variations in the incidence of deliberate self-harm (DSH) and suicide have been shown to be associated with area-based measures of socio-economic deprivation and social fragmentation. Previous studies have been subject to methodological limitations. None has investigated whether ecological associa...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003993
更新日期:2001-07-01 00:00:00
abstract::Experts have raised concerns that oxytocin for labor induction and augmentation may have detrimental effects on the neurodevelopment of children. To investigate whether there is the reason for concern, we reviewed and evaluated the available evidence by searching databases with no language or date restrictions up to 9...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291718003021
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000542
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:An uneven neurocognitive profile is a hallmark of autism spectrum disorder (ASD). Studies focusing on the visual memory performance in ASD have shown controversial results. We investigated visual memory and sustained attention in youths with ASD and typically developing (TD) youths. METHOD:We recruited 143 ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714003201
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:This experiment examines two aspects of delusional cognition that have been reported clinically but not investigated empirically. These are the incorporation of potentially conflicting information into the recall of delusion-related scripts and the type and amount of material produced additional to that pres...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170200538x
更新日期:2002-04-01 00:00:00