Abstract:
:Platelet MAO activity was found to be elevated in primary depressive illness, and the severity to correlate positively with MAO activity. The reactive depression subgroup's mean platelet MAO activity was not significantly different from that of the controls. The endogenous group's unipolar and bipolar subgroups had significantly different platelet MAO activity, respectively high and low. The differences in MAO activity between unipolar and bipolar patients appeared to persist in the well state, but not after lithium carbonate therapy. These differences in MAO activity were apparent with the substrate tyramine but not with benzylamine. Altered MAO activity in patients with affective disorders may be determined through genetic mechanisms.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Mann Jdoi
10.1017/s0033291700034048subject
Has Abstractpub_date
1979-11-01 00:00:00pages
729-36issue
4eissn
0033-2917issn
1469-8978journal_volume
9pub_type
杂志文章abstract::This paper presents the results of a study of unemployment among British Asians living in the north of England. The sample comprises 139 employed and unemployed men. Using standardized psychological questionnaires with a semi-structured interview schedule, the psychological consequences of unemployment are examined in...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170002732x
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Psychosocial and inflammatory factors have been associated with fatigue in breast cancer survivors. Nevertheless, the relative contribution and/or interaction of these factors with cancer-related fatigue have not been well documented. METHOD:This cross-sectional study enrolled 111 stage 0-III breast cancer ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000150
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Interest in the mental health of women deployed to modern military campaigns is increasing, although research examining gender differences is limited. Little is known about experiences women have had on these deployments, or whether men and women respond differently to combat exposure. METHOD:The current st...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171100290X
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Major depressive disorder during pregnancy associates with potentially detrimental consequences for mother and child. The current study examined peripheral blood gene expression as a potential biomarker for prenatal depressive symptoms. METHOD:Maternal RNA from whole blood, plasma and the Beck Depression In...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002121
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:We examined the prevalence of self-perceived respiratory symptoms (SRS) in the absence of any objective findings of respiratory pathology, and the association of such prevalence with psychological factors and healthcare use in the general population. METHODS:The study was conducted among a nationally repres...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718000582
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711000857
更新日期:2011-12-01 00:00:00
abstract::This paper analyses patterns of episodes of anxiety and depression as recorded by 22 general practices which took part in the Second National Morbidity Survey (RCGP, 1980). The data comprise 6 years' records. Simple Markov chains are fitted to each age-group of men and women, and the inter-practice variation in the re...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700051643
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. METHODS:We investiga...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002587
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Virtual reality (VR) may enhance the effectiveness of psychological interventions for acute pain. We conducted a meta-analysis to assess the efficacy and safety of VR-based interventions for pain associated with medical procedures. METHODS:We searched PubMed, EMBASE, the Cochrane Library, and PsycINFO until...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001855
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Cognitive impairment and negative symptoms are two of the primary features of schizophrenia associated with poor social functioning. We examined the relationships between clinical characteristics, specific cognitive abilities and social skills performance in middle-aged and older out-patients with schizophre...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707001304
更新日期:2008-05-01 00:00:00
abstract::Biochemical studies of manic-depressive psychosis usually correlates biochemical findings with current affective state and hence any significant findings could be secondary to mood change. The present study attempts to correlate measures of the erythrocyte membrane cation carrier with clinical events, remote in time f...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700013805
更新日期:1976-05-01 00:00:00
abstract:BACKGROUND:Post-traumatic symptomatology is one of the signature effects of the pernicious exposures endured by responders to the World Trade Center (WTC) disaster of 11 September 2001 (9/11), but the long-term extent of diagnosed Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) post-traumati...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002184
更新日期:2016-03-01 00:00:00
abstract::In constructing a new self-report questionnaire for measuring self esteem, the aim has been to satisfy psychometric requirements without sacrificing the intuitive meaning of the concept. Self esteem is seen as a composite, and examination of its components may have more analytic or predictive value than 'global' score...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170001254x
更新日期:1989-05-01 00:00:00
abstract::Bullying victimization is a topic of concern for youths, parents, school staff and mental health practitioners. Children and adolescents who are victimized by bullies show signs of distress and adjustment problems. However, it is not clear whether bullying is the source of these difficulties. This paper reviews empiri...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291709991383
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Early life maltreatment (ELM), borderline personality disorder (BPD), and major depressive disorder (MDD) have been associated with empathy deficits in different domains. Lack of maternal empathy has also been related to child behavioral problems. As ELM, BPD, and MDD often co-occur, we aimed to identify dis...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001107
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002133
更新日期:2012-06-01 00:00:00
abstract::Preliminary data from the National Institute of Mental Health-Clinical Research Branch Collaborative Program on the Psychobiology of Depression dealing with the human growth hormone (hGH) response to the Insulin Tolerance Test (ITT) during the pre-treatment (drug-free) period of the study are presented in this paper. ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700043270
更新日期:1982-02-01 00:00:00
abstract:BACKGROUND:Mental stress is associated with higher mortality, but it remains controversial whether the association is causal or a consequence of a higher physical disease burden in those with a high mental stress load. Understanding causality is important when developing targeted interventions. We aimed to estimate the...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717002380
更新日期:2018-07-01 00:00:00
abstract::The prevalence of culture-bound syndromes such as eating disorders in the countries of Central and Eastern Europe is unclear and comparative epidemiological studies are lacking. Before the political changes in 1989 we therefore investigated eating disorders, eating attitudes and psychological health in two Eastern Eur...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700037521
更新日期:1995-09-01 00:00:00
abstract::Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032748
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Temperament and personality traits, including negative emotionality/neuroticism, may represent risk factors for eating disorders. Further, risk factors may differ by sex. We examined longitudinal temperament/personality pathways of risk for purging and binge eating in youth stratified by sex using data from ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001818
更新日期:2020-08-01 00:00:00
abstract::It is well established that a diagnosis of cancer and the subsequent treatment can cause a great deal of stress, and the need for psychosocial support is increasingly being advocated. The data for the efficacy of intervention programmes are reviewed. The evidence relating to the benefits gained by patients is equivoca...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700051552
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Psychiatric rehabilitation (PR) can improve functioning in people with severe mental illness (SMI), but outcomes are still suboptimal. Cognitive impairments have severe implications for functioning and might reduce the effects of PR. It has been demonstrated that performance in cognitive tests can be improve...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S003329171800418X
更新日期:2019-07-01 00:00:00
abstract::Eighty-three chronic obstructive bronchitic patients were psychologically assessed before being randomly allocated to 1 of 3 management regimes. The following measures were taken: psychiatric disturbance, personality, social-desirability response set, vocabulary, expectations about treatment, attitudes and beliefs abo...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700021565
更新日期:1979-02-01 00:00:00
abstract:BACKGROUND:The differential strength of correlation between symptoms, cognition and other patient characteristics with community functioning in first-episode psychosis has not been fully investigated. METHOD:In a sample of 66 first-episode psychosis patients demographic variables, ratings of pre-morbid adjustment, pos...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291702006050
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Individual variation in the clinical course of bipolar disorder may have prognostic and therapeutic implications but is poorly reflected in current classifications. We aimed to establish a typology of the individual clinical trajectories based on detailed prospective medium-term follow-up. Method Latent clas...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712001523
更新日期:2013-04-01 00:00:00
abstract::To investigate the relationships between cardiovascular variables (SBP, DBP, and HR) and circulating natural killer (NK) cell numbers, 70 male volunteers were subjected to a rest condition (N = 30) or a stressful laboratory task (N = 40). At baseline, no significant relationships could be demonstrated between the numb...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291700036229
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:The importance of genetic factors in the aetiology of manic-depressive illness (MDI) has been repeatedly confirmed and indicators of vulnerability to the illness in families with affective disorders are needed. Abnormal event-related potentials (ERP) may be markers of genetic vulnerability to mental illness....
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799001944
更新日期:2000-05-01 00:00:00
abstract::Data from a general population survey of psychiatric disorder in Camberwell were used to calculate the risk of a CATEGO-defined depressive episode before the age of 65, using a modification of Strömgren's method. Current depression was defined as cases within the relevant categories of the CATEGO program and at thresh...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700012435
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Major depressive disorder (MDD) is accompanied by alterations in grey matter volume. However, the biological processes associated with regional structural perturbations remain elusive. METHODS:We applied integrative omics analysis to investigate specialized transcriptome signatures and translational determi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720002676
更新日期:2020-07-29 00:00:00