Integrative omics analysis identifies differential biological pathways that are associated with regional grey matter volume changes in major depressive disorder.

abstract：BACKGROUND:To assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States. METHOD:Data came from a large representative sample of the US population. F...

journal_title：Psychological medicine

authors： Schneier FR,Foose TE,Hasin DS,Heimberg RG,Liu SM,Grant BF,Blanco C

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:In schizophrenia, affective disorders, and obsessive-compulsive disorder (OCD) dysfunction of frontal neuronal circuits has been suggested. Such impairments imply corresponding oculomotor deficits. METHOD:Eye movement response to foveofugal and foveopetal step-ramp stimuli was recorded within the same study...

journal_title：Psychological medicine

authors： Lencer R,Trillenberg P,Trillenberg-Krecker K,Junghanns K,Kordon A,Broocks A,Hohagen F,Heide W,Arolt V

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...

journal_title：Psychological medicine

authors： Sutin AR,Stephan Y,Terracciano A

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Assaultive violence events are associated with increased risk for adverse psychiatric outcomes, including post-traumatic stress (PTS), depression, and generalized anxiety. Prior research has indicated that economic, legal, and social stressors that could follow assaultive events may explain the increased ris...

journal_title：Psychological medicine

authors： Lowe SR,Joshi S,Galea S,Aiello AE,Uddin M,Koenen KC,Cerdá M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Little is known about the mental health of partners of survivors of high levels of trauma in post-conflict countries. METHOD:We studied 677 spouse dyads (n = 1354) drawn from a community survey (response 82.4%) in post-conflict Timor-Leste. We used culturally adapted measures of post-traumatic stress disord...

journal_title：Psychological medicine

authors： Silove DM,Tay AK,Steel Z,Tam N,Soares Z,Soares C,Dos Reis N,Alves A,Rees S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Prior optical coherence tomography (OCT) studies of schizophrenia have identified thinning of retinal layers. However, findings have varied across reports, and most studies have had serious methodological limitations. To address unresolved issues, we determined whether: (1) retinal thinning in schizophrenia ...

journal_title：Psychological medicine

authors： Silverstein SM,Paterno D,Cherneski L,Green S

更新日期：2018-09-01 00:00:00

abstract：:A non-recursive structural equation model designed to examine the reciprocal relationship between life event reports and depressive symptoms in women is presented. The model was fitted to data from a 2-year longitudinal study of life events and depression in a sample of women with 5-year-old children. The findings sug...

journal_title：Psychological medicine

authors： Fergusson DM,Horwood LJ

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:There is still a relative paucity of information about the long-term course of depression. METHODS:Consecutive patients admitted to a teaching hospital psychiatry unit with symptoms of depression, previously assessed at 6 months and 2, 5 and 15 years after index admission, were reviewed at 25 years (N = 49,...

journal_title：Psychological medicine

authors： Brodaty H,Luscombe G,Peisah C,Anstey K,Andrews G

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Clinical intuition suggests that personality disorders hinder the treatment of depression, but research findings are mixed. One reason for this might be the way in which current assessment measures conflate general aspects of personality disorders, such as overall severity, with specific aspects, such as sty...

journal_title：Psychological medicine

authors： Constantinou MP,Frueh BC,Fowler JC,Allen JG,Madan A,Oldham JM,Fonagy P

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Mild traumatic brain injury (mTBI) is being claimed as the 'signature' injury of the Iraq war, and is believed to be the cause of long-term symptomatic ill health (post-concussional syndrome; PCS) in an unknown proportion of military personnel. METHOD:We analysed cross-sectional data from a large, randomly ...

journal_title：Psychological medicine

authors： Fear NT,Jones E,Groom M,Greenberg N,Hull L,Hodgetts TJ,Wessely S

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Abnormalities in the anterior inter-hemispheric connectivity have previously been implicated in major depressive disorder. Disruptions in fractional anisotropy in the callosum and fornix have been reported in schizophrenia and major depressive disorder. Oligodendrocyte density and overall size of the callosu...

journal_title：Psychological medicine

authors： Williams MR,Sharma P,Fung KL,Pearce RK,Hirsch SR,Maier M

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) has been called one of the signature injuries of the Iraq War. In this review prevalence estimates of PTSD are summarized and discrepancies are discussed in relation to methodological differences between studies. METHOD:We searched for population-based studies with a mi...

journal_title：Psychological medicine

authors： Sundin J,Fear NT,Iversen A,Rona RJ,Wessely S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Several case reports and reviews have suggested an increased incidence of schizophrenia or bipolar disorder among persons with sex chromosome aneuploidies, but this observation may have been caused by biased sampling. METHODS:The 1122 individuals with sex chromosome aneuploidies registered in the Danish Cyt...

journal_title：Psychological medicine

authors： Mors O,Mortensen PB,Ewald H

更新日期：2001-04-01 00:00:00

abstract：:The question addressed to in this paper is whether severely mentally ill patients are treated differently in a community mental health service without the back-up of a mental hospital (south-Verona, Italy) compared with an institution-based system in which mental hospitals, although highly modernized, are still predom...

journal_title：Psychological medicine

authors： Sytema S,Micciolo R,Tansella M

更新日期：1996-01-01 00:00:00

abstract：:In the face of shifting demographics and an increase in human longevity, it is important to examine carefully what is known about cognitive ageing, and to identify and promote possibly malleable lifestyle and health-related factors that might mitigate age-associated cognitive decline. The Lothian Birth Cohorts of 1921...

journal_title：Psychological medicine

authors： Corley J,Cox SR,Deary IJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:A few previous studies suggest that a large number of individuals do not present at hospital following a suicide attempt, complicating recurrence prevention and prevalence estimation. METHODS:Data were extracted from a regular phone survey in representative samples of the French population aged 18-75 years ...

journal_title：Psychological medicine

authors： Jollant F,Hawton K,Vaiva G,Chan-Chee C,du Roscoat E,Leon C

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:A long-standing issue in the health anxiety literature is the extent to which health anxiety is a dimensional or a categorical construct. This study explores this question directly using taxometric procedures. METHOD:Seven hundred and eleven working adults completed an index of health anxiety [the Whiteley ...

journal_title：Psychological medicine

authors： Ferguson E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The correlates of insight in early-onset psychosis have received little previous attention. METHOD:We studied clinical correlates of insight in a sample of 110 adolescent recent-onset psychosis patients (mean age 15.53 years; psychotic symptoms present for <6 months). Insight was measured with the Scale to ...

journal_title：Psychological medicine

authors： Parellada M,Fraguas D,Bombín I,Otero S,Castro-Fornieles J,Baeza I,Gonzalez-Pinto A,Graell M,Soutullo C,Paya B,Arango C

更新日期：2009-09-01 00:00:00

abstract：:In constructing a new self-report questionnaire for measuring self esteem, the aim has been to satisfy psychometric requirements without sacrificing the intuitive meaning of the concept. Self esteem is seen as a composite, and examination of its components may have more analytic or predictive value than 'global' score...

journal_title：Psychological medicine

authors： Robson P

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Urban birth, a risk factor for schizophrenia, is more frequent among second-generation immigrants. The aim of the current study was to determine whether the increased risk for schizophrenia found in second-generation immigrants is explained by the degree of urbanization of birthplace and/or factors related t...

journal_title：Psychological medicine

authors： Cantor-Graae E,Pedersen CB

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:There is evidence of executive function impairment in obsessive compulsive disorder (OCD) that potentially contributes to symptom development and maintenance. Nevertheless, the precise nature of these executive impairments and their neural basis remains to be defined. METHOD:We compared stopping and shiftin...

journal_title：Psychological medicine

authors： Morein-Zamir S,Voon V,Dodds CM,Sule A,van Niekerk J,Sahakian BJ,Robbins TW

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Studies exploring gene-environment interplay in affective disorders now include very large numbers of participants. Methods for evaluating the role of adversity in such studies need to be developed that do not rely on lengthy and labour-intensive interviews. In the present study, a brief questionnaire method...

journal_title：Psychological medicine

authors： Hosang GM,Korszun A,Jones L,Jones I,Gray JM,Gunasinghe CM,McGuffin P,Farmer AE

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Hierarchical structural models of psychopathology rarely extend to obsessive-compulsive spectrum disorders. The current study sought to examine the higher-order structure of the obsessive-compulsive and related disorders (OCRDs) in DSM-5: obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysm...

journal_title：Psychological medicine

authors： Snorrason I,Beard C,Peckham AD,Björgvinsson T

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:This two-stage prevalence survey involved geographically delimited areas, four urban (Liverpool, Newcastle, Nottingham and Oxford) and two rural (Cambridgeshire and Gwynedd), including institutions. METHODS:Stratified random population samples of people in their 65th year and above, from Family Health Servi...

journal_title：Psychological medicine

authors：

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Little is known about how continuation and maintenance cognitive-behavioural therapy (CBT) influences important psychological constructs that may be associated with long-term outcome of major depressive disorder. The goal of this study was to examine whether CBT would help maintain attributional style change...

journal_title：Psychological medicine

authors： Petersen T,Harley R,Papakostas GI,Montoya HD,Fava M,Alpert JE

更新日期：2004-04-01 00:00:00

abstract：:The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was used to assess changes in brain 5-hydroxytryptamine (5-HT) function in normal male and female subjects, following a three week period of dieting. In women, but not men, there was a marked increase in the prolactin respo...

journal_title：Psychological medicine

authors： Goodwin GM,Fairburn CG,Cowen PJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Psychiatric rehabilitation (PR) can improve functioning in people with severe mental illness (SMI), but outcomes are still suboptimal. Cognitive impairments have severe implications for functioning and might reduce the effects of PR. It has been demonstrated that performance in cognitive tests can be improve...

journal_title：Psychological medicine

authors： van Duin D,de Winter L,Oud M,Kroon H,Veling W,van Weeghel J

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Depression is a challenge to diagnose reliably and the current gold standard for trials of DSM-5 has been in agreement between two or more medical specialists. Research studies aiming to objectively predict depression have typically used brain scanning. Less expensive methods from cognitive neuroscience may ...

journal_title：Psychological medicine

authors： Stolicyn A,Steele JD,Seriès P

更新日期：2020-11-09 00:00:00

abstract：:Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...

journal_title：Psychological medicine

authors： Henderson AS,Jorm AF,Korten AE,Creasey H,McCusker E,Broe GA,Longley W,Anthony JC

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The ability to decode emotional information from facial expressions is crucial for successful social interaction. Borderline personality disorder (BPD) is characterized by serious problems in interpersonal relationships and emotional functioning. Empirical research on facial emotion recognition in BPD has be...

journal_title：Psychological medicine

authors： Dyck M,Habel U,Slodczyk J,Schlummer J,Backes V,Schneider F,Reske M

更新日期：2009-05-01 00:00:00