Smooth pursuit deficits in schizophrenia, affective disorder and obsessive-compulsive disorder.

abstract：BACKGROUND:Clinical intuition suggests that personality disorders hinder the treatment of depression, but research findings are mixed. One reason for this might be the way in which current assessment measures conflate general aspects of personality disorders, such as overall severity, with specific aspects, such as sty...

journal_title：Psychological medicine

authors： Constantinou MP,Frueh BC,Fowler JC,Allen JG,Madan A,Oldham JM,Fonagy P

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...

journal_title：Psychological medicine

authors： Laskemoen JF,Aas M,Vaskinn A,Berg AO,Lunding SH,Barrett EA,Melle I,Simonsen C

更新日期：2020-04-23 00:00:00

abstract：BACKGROUND:Delusional disorder (DD) and obsessive-compulsive disorder (OCD) have been investigated in previous studies using probabilistic reasoning paradigms and abnormalities in each group have been reported. No study to date has compared results between these groups. This study compares patients with these disorders...

journal_title：Psychological medicine

authors： Fear CF,Healy D

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The increased use of the MATRICS Consensus Cognitive Battery (MCCB) to investigate cognitive dysfunctions in schizophrenia fostered interest in its sensitivity in the context of family studies. As various measures of the same cognitive domains may have different power to distinguish between unaffected relati...

journal_title：Psychological medicine

authors： Mucci A,Galderisi S,Green MF,Nuechterlein K,Rucci P,Gibertoni D,Rossi A,Rocca P,Bertolino A,Bucci P,Hellemann G,Spisto M,Palumbo D,Aguglia E,Amodeo G,Amore M,Bellomo A,Brugnoli R,Carpiniello B,Dell'Osso L,Di Fabio

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Most research on the prevalence, distribution, and psychiatric comorbidity of intellectual disability (ID) relies on clinical samples, limiting the generalizability and utility of ID assessment in a legal context. This study assessed ID prevalence in a population-representative sample of US adolescents and e...

journal_title：Psychological medicine

authors： Platt JM,Keyes KM,McLaughlin KA,Kaufman AS

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Depression increases the risk of subsequent vascular events in both cardiac and non-cardiac patients. Atherosclerosis, the underlying process leading to vascular events, has been associated with depression. This association, however, may be confounded by the somatic-affective symptoms being a consequence of ...

journal_title：Psychological medicine

authors： Bus BA,Marijnissen RM,Holewijn S,Franke B,Purandare N,de Graaf J,den Heijer M,Buitelaar JK,Voshaar RC

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:There is an emerging consensus in developmental psychopathology that irritable youth are at risk for developing internalizing problems later in life. The current study explored if irritability in youth is multifactorial and the impact of irritability dimensions on psychopathology outcomes in adulthood. METH...

journal_title：Psychological medicine

authors： Hawes MT,Carlson GA,Finsaas MC,Olino TM,Seely JR,Klein DN

更新日期：2020-12-01 00:00:00

abstract：:A review of research on kleptomania--the syndrome of compulsive stealing--suggests that kleptomania may be a common disorder, especially among women, and that it may frequently be associated with other forms of psychopathology, such as mood, anxiety, and eating disorders. There appears to be a range of abnormal or non...

journal_title：Psychological medicine

authors： McElroy SL,Hudson JI,Pope HG,Keck PE

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that purging disorder (PD) may be a common eating disorder that is associated with clinically significant levels of distress and high levels of psychiatric co-morbidity. However, no study has established evidence of disorder-related impairment or whether distress is specifically relate...

journal_title：Psychological medicine

authors： Keel PK,Wolfe BE,Gravener JA,Jimerson DC

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Little is known about the mental health of partners of survivors of high levels of trauma in post-conflict countries. METHOD:We studied 677 spouse dyads (n = 1354) drawn from a community survey (response 82.4%) in post-conflict Timor-Leste. We used culturally adapted measures of post-traumatic stress disord...

journal_title：Psychological medicine

authors： Silove DM,Tay AK,Steel Z,Tam N,Soares Z,Soares C,Dos Reis N,Alves A,Rees S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Developmental adversities may be risk factors for adult suicidal behavior, but this relationship has rarely been studied prospectively. The present study examined the association between childhood adversities and new onset suicidal ideation and attempts in an adult population-based sample. METHOD:The study ...

journal_title：Psychological medicine

authors： Enns MW,Cox BJ,Afifi TO,De Graaf R,Ten Have M,Sareen J

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Stress and vulnerability likely interact to play a major role in psychosis. While much has been written about the neural diathesis-stress model in psychosis and its clinical risk states, little is known about HPA axis biomarkers in non-help-seeking individuals at familial high risk (FHR). We sought to prospe...

journal_title：Psychological medicine

authors： Shah JL,Tandon N,Howard ER,Mermon D,Miewald JM,Montrose DM,Keshavan MS

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. ...

journal_title：Psychological medicine

authors： Lowe SR,Ratanatharathorn A,Lai BS,van der Mei W,Barbano AC,Bryant RA,Delahanty DL,Matsuoka YJ,Olff M,Schnyder U,Laska E,Koenen KC,Shalev AY,Kessler RC

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Prior optical coherence tomography (OCT) studies of schizophrenia have identified thinning of retinal layers. However, findings have varied across reports, and most studies have had serious methodological limitations. To address unresolved issues, we determined whether: (1) retinal thinning in schizophrenia ...

journal_title：Psychological medicine

authors： Silverstein SM,Paterno D,Cherneski L,Green S

更新日期：2018-09-01 00:00:00

abstract：:The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was used to assess changes in brain 5-hydroxytryptamine (5-HT) function in normal male and female subjects, following a three week period of dieting. In women, but not men, there was a marked increase in the prolactin respo...

journal_title：Psychological medicine

authors： Goodwin GM,Fairburn CG,Cowen PJ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Alcohol is commonly considered to be associated with persistence of common mental disorder (CMD; anxiety/depression). However no community-based longitudinal studies have investigated the direction of causality. METHOD:We examined the association between alcohol consumption and recovery from CMD using data ...

journal_title：Psychological medicine

authors： Haynes JC,Farrell M,Singleton N,Meltzer H,Araya R,Lewis G,Wiles NJ

更新日期：2008-03-01 00:00:00

abstract：:We have attempted to clarify clinical differentiating features of psychotic depression. Forty-six depressed subjects meeting DSM-III-R criteria for major depression with psychotic features were compared with (i) DSM-defined melancholic, (ii) Newcastle-defined endogenous, and (iii) a residual DSM-defined major depressi...

journal_title：Psychological medicine

authors： Parker G,Hadzi-Pavlovic D,Brodaty H,Austin MP,Mitchell P,Wilhelm K,Hickie I

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Aggression has been suggested to be related to abnormal brain 5-HT activity. This amine is synthesized in brain from tryptophan, which is transported through the blood-brain barrier in competition with other amino acids. The relationship between tryptophan and its endogenous amino acid competitors in plasma ...

journal_title：Psychological medicine

authors： Eriksson T,Lidberg L

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Parental characteristics and practices predict borderline personality disorder (BPD) symptoms in children. However, it is difficult to disentangle whether these effects are genetically or environmentally mediated. The present study examines the contributions of genetic and environmental influences by compari...

journal_title：Psychological medicine

authors： Fatimah H,Wiernik BM,Gorey C,McGue M,Iacono WG,Bornovalova MA

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Few population studies have investigated the functional disabilities that accompany specific psychiatric diagnoses. This study assesses the nature and strength of current and residual impairments in various functional domains of life. METHODS:Data were derived from the Netherlands Mental Health Survey and I...

journal_title：Psychological medicine

authors： Bijl RV,Ravelli A

更新日期：2000-05-01 00:00:00

abstract：:Functional and phenotypic immunological parameters were examined immediately before, after, and 30 minutes after experimentally-induced short-term positive (happiness) and negative (anxiety, depression) affective states and a neutral state, in five healthy subjects. Results indicated that all affective states induced ...

journal_title：Psychological medicine

authors： Futterman AD,Kemeny ME,Shapiro D,Polonsky W,Fahey JL

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the d...

journal_title：Psychological medicine

authors： González-Ortega I,González-Pinto A,Alberich S,Echeburúa E,Bernardo M,Cabrera B,Amoretti S,Lobo A,Arango C,Corripio I,Vieta E,de la Serna E,Rodriguez-Jimenez R,Segarra R,López-Ilundain JM,Sánchez-Torres AM,Cuesta MJ,PEPs

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Children of parents with mood and psychotic disorders are at elevated risk for a range of behavioral and emotional problems. However, as the usual reporter of psychopathology in children is the parent, reports of early problems in children of parents with mood and psychotic disorders may be biased by the par...

journal_title：Psychological medicine

authors： Sandstrom A,MacKenzie L,Pizzo A,Fine A,Rempel S,Howard C,Stephens M,Patterson VC,Drobinin V,Van Gestel H,Howes Vallis E,Zwicker A,Propper L,Abidi S,Bagnell A,Lovas D,Cumby J,Alda M,Uher R,Pavlova B

更新日期：2020-04-01 00:00:00

abstract：:Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, rev...

journal_title：Psychological medicine

authors： Brown RG,MacCarthy B

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that depressed patients are impaired in their ability to shift attention from one emotional category to another, but whether this shifting deficit is more evident ...

journal_title：Psychological medicine

authors： Murphy FC,Michael A,Sahakian BJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes. METHOD:Family practice attendees were recruited between April 2003 and February 2005 and followed over 24 months in the UK, Spain...

journal_title：Psychological medicine

authors： King M,Bottomley C,Bellón-Saameño JA,Torres-Gonzalez F,Švab I,Rifel J,Maaroos HI,Aluoja A,Geerlings MI,Xavier M,Carraça I,Vicente B,Saldivia S,Nazareth I

更新日期：2011-08-01 00:00:00

abstract：:Using the 40-item Eating Attitudes Test and other self-report questions, a two-stage screening survey of 1020 (F 646, M 374) Chinese bilingual university students in Hong Kong showed that although female students were 'underweight' by Western standard, the majority of them and nearly all female students above a body m...

journal_title：Psychological medicine

authors： Lee S

更新日期：1993-05-01 00:00:00

abstract：:We recently completed a case-control study of 100 literally homeless and 100 never homeless indigent schizophrenic men in New York City, in which concurrent substance abuse and antisocial personality disorder were widespread. In this paper we probe the correlates of 'pure' schizophrenia (single disorder, N = 60), schi...

journal_title：Psychological medicine

authors： Caton CL,Shrout PE,Eagle PF,Opler LA,Felix A

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Nitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS activity of patients with a MDE to that of healthy controls (HC); (2)...

journal_title：Psychological medicine

authors： Loeb E,El Asmar K,Trabado S,Gressier F,Colle R,Rigal A,Martin S,Verstuyft C,Fève B,Chanson P,Becquemont L,Corruble E

更新日期：2020-06-11 00:00:00

abstract：:Preliminary data from the National Institute of Mental Health-Clinical Research Branch Collaborative Program on the Psychobiology of Depression dealing with the human growth hormone (hGH) response to the Insulin Tolerance Test (ITT) during the pre-treatment (drug-free) period of the study are presented in this paper. ...

journal_title：Psychological medicine

authors： Koslow SH,Stokes PE,Mendels J,Ramsey A,Casper R

更新日期：1982-02-01 00:00:00