The role of depot neuroleptics in the treatment of schizophrenic patients.

abstract：BACKGROUND:The association between cigarette smoking and psychosis remains unexplained, but could relate to causal effects in both directions, confounding by socioeconomic factors, such as ethnicity, or use of other substances, including cannabis. Few studies have evaluated the association between cigarettes and psycho...

journal_title：Psychological medicine

authors： Bhavsar V,Jauhar S,Murray RM,Hotopf M,Hatch SL,McNeill A,Boydell J,MacCabe JH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Morphometric endophenotypes which have been proposed for psychotic disorders include lateral ventricular enlargement and hippocampal volume reductions. Genetic epidemiological studies support an overlap between schizophrenia and bipolar disorder, and COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes have been implica...

journal_title：Psychological medicine

authors： Dutt A,McDonald C,Dempster E,Prata D,Shaikh M,Williams I,Schulze K,Marshall N,Walshe M,Allin M,Collier D,Murray R,Bramon E

更新日期：2009-11-01 00:00:00

abstract：:There is little evidence of a curvilinear relationship between pre-operative emotionality and post-operative adjustment, as predicted by a model which supposes that moderate preoperative anxiety assists adjustment. This paper suggests that the negative affect, or stress, associated with the work of worry should be dis...

journal_title：Psychological medicine

authors： Ray C,Fitzgibbon G

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, but risk factors associated with cognitive deficits in euthymic BD are still poorly understood. We aimed to validate classification criteria for the identification of clinically significant cognitive...

journal_title：Psychological medicine

authors： Roux P,Etain B,Cannavo AS,Aubin V,Aouizerate B,Azorin JM,Bellivier F,Belzeaux R,Bougerol T,Cussac I,Courtet P,Kahn JP,Leboyer M,M'Bailara K,Payet MP,Olié E,FondaMental Advanced Centers of Expertise in Bipolar Disorders (F

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Hip fracture is common in the elderly. Previous studies suggest that psychiatric illness is common and predicts poor outcome, but have methodological weaknesses. Further studies are required to address this important issue. METHODS:We prospectively recruited 731 elderly participants with hip fracture in two...

journal_title：Psychological medicine

authors： Holmes J,House A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Moodscope is an entirely service-user-developed online mood-tracking and feedback tool with built-in social support, designed to stabilize and improve mood. Many free internet tools are available with no assessment of acceptability, validity or usefulness. This study provides an exemplar for future assessmen...

journal_title：Psychological medicine

authors： Drake G,Csipke E,Wykes T

更新日期：2013-07-01 00:00:00

abstract：:Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...

journal_title：Psychological medicine

authors： Maier M,Ron MA,Barker GJ,Tofts PS

更新日期：1995-11-01 00:00:00

abstract：:A detailed analysis of the results of a multi-centre clinical trial shows that, while the relapse rate following recovery from an operationally defined depressive illness was smaller among patients subsequently treated with either amitryptiline or lithium than with a placebo, there was no clinically significant differ...

journal_title：Psychological medicine

authors： Glen AI,Johnson AL,Shepherd M

更新日期：1984-02-01 00:00:00

abstract：:Difficulties in set-shifting are commonly reported in both autism spectrum disorder (ASD) and anorexia nervosa (AN) populations. Despite this, it is not known whether this cognitive profile persists across different ages, or whether the profiles seen in ASD and AN are comparable. This systematic review and meta-analys...

journal_title：Psychological medicine

authors： Westwood H,Stahl D,Mandy W,Tchanturia K

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Neuroticism has been shown to increase the risk of depression whereas extraversion is associated with a reduction of risk. These personality traits play a central role in aetiological theories of affective disorder but their role in schizophrenia is unclear. In this study, the risk for schizophrenia associat...

journal_title：Psychological medicine

authors： Van Os J,Jones PB

更新日期：2001-08-01 00:00:00

abstract：BACKGROUNDS:Cigarette smoking is strongly associated with major depressive disorder (MDD). However, any genetic etiology of such comorbidity and causal relations is poorly understood, especially at the genome-wide level. METHODS:In the present in silico research, we analyzed summary data from the genome-wide associati...

journal_title：Psychological medicine

authors： Yao Y,Xu Y,Cai Z,Liu Q,Ma Y,Li AN,Payne TJ,Li MD

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. ...

journal_title：Psychological medicine

authors： Lowe SR,Ratanatharathorn A,Lai BS,van der Mei W,Barbano AC,Bryant RA,Delahanty DL,Matsuoka YJ,Olff M,Schnyder U,Laska E,Koenen KC,Shalev AY,Kessler RC

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Prevalence of childhood anxiety disorders at specific ages and genetic etiological influences on anxiety disorders in young children have been little studied. The present study reports prevalence estimates in a community sample of 6-year-old twins, and patterns of genetic and environmental influences on thes...

journal_title：Psychological medicine

authors： Bolton D,Eley TC,O'Connor TG,Perrin S,Rabe-Hesketh S,Rijsdijk F,Smith P

更新日期：2006-03-01 00:00:00

abstract：:One hundred and twenty women recruited from attenders at the antenatal clinic of the Obstetrics Department of a general hospital were asked to complete ad hoc questionnaires during pregnancy; they were then interviewed by psychiatrists using a structured diagnostic interview, the Schedule for Affective Disorders and S...

journal_title：Psychological medicine

authors： Kitamura T,Shima S,Sugawara M,Toda MA

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Cognitive-behavioral therapy (CBT) is thought to be useful for chronic pain, with the pathology of the latter being closely associated with cognitive-emotional components. However, there are few resting-state functional magnetic resonance imaging (R-fMRI) studies. We used the independent component analysis m...

journal_title：Psychological medicine

authors： Yoshino A,Okamoto Y,Okada G,Takamura M,Ichikawa N,Shibasaki C,Yokoyama S,Doi M,Jinnin R,Yamashita H,Horikoshi M,Yamawaki S

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:There is evidence that patients with chronic fatigue syndrome (CFS) have mild hypocortisolism. The clinical significance of this is unclear. We aimed to determine whether hypocortisolism exerted any effect on the response of CFS to cognitive behavioural therapy (CBT). METHOD:We measured 24-h urinary free co...

journal_title：Psychological medicine

authors： Roberts AD,Charler ML,Papadopoulos A,Wessely S,Chalder T,Cleare AJ

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Evidence from high-income countries suggests that childhood trauma is associated with schizophrenia. Studies of childhood trauma and schizophrenia in low and middle income (LMIC) countries are limited. This study examined the prevalence of childhood traumatic experiences among cases and controls and the rela...

journal_title：Psychological medicine

authors： Mall S,Platt JM,Temmingh H,Musenge E,Campbell M,Susser E,Stein DJ

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Attention deficit hyperactivity disorder (ADHD) often, but not always, persists into adulthood. Investigations of the associations between clinical and biological markers of persistence can shed light on causal pathways. It has been proposed that compensatory improvements in executive neuropsychological func...

journal_title：Psychological medicine

authors： Coghill DR,Hayward D,Rhodes SM,Grimmer C,Matthews K

更新日期：2014-04-01 00:00:00

abstract：:100 randomly selected mildly or moderately mentally retarded adults were assessed for personality disorder using the Standardized Assessment of Personality devised by Mann et al. (1981). By the terms of this instrument 56% of patients showed features of abnormal personality, and in 22% this abnormality was marked, sug...

journal_title：Psychological medicine

authors： Reid AH,Ballinger BR

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:The output of many healthy physiological systems displays fractal fluctuations with self-similar temporal structures. Altered fractal patterns are associated with pathological conditions. There is evidence that patients with bipolar disorder have altered daily behaviors. METHODS:To test whether fractal patt...

journal_title：Psychological medicine

authors： Knapen SE,Li P,Riemersma-van der Lek RF,Verkooijen S,Boks MPM,Schoevers RA,Scheer FAJL,Hu K

更新日期：2020-04-01 00:00:00

abstract：:In an earlier paper we found that a model of depression developed on a sample of women in a London population was confirmed in a female population in the Outer Hebrides. Differences in the rates of onset and chronic cases between the two populations, however, suggested that the Scottish women might be more likely to b...

journal_title：Psychological medicine

authors： Prudo R,Brown GW,Harris T,Dowland J

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:The differential strength of correlation between symptoms, cognition and other patient characteristics with community functioning in first-episode psychosis has not been fully investigated. METHOD:In a sample of 66 first-episode psychosis patients demographic variables, ratings of pre-morbid adjustment, pos...

journal_title：Psychological medicine

authors： Malla AK,Norman RM,Manchanda R,Townsend L

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Prior studies have suggested that major depressive disorder (MDD) with pre-adult onset represents a distinct subtype with greater symptom severity and higher rates of suicidal ideation. Whether these patients have poorer response to various types of antidepressant treatment than those with adult-onset MDD is...

journal_title：Psychological medicine

authors： Sung SC,Wisniewski SR,Balasubramani GK,Zisook S,Kurian B,Warden D,Trivedi MH,Rush AJ,CO-MED Study Team.

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Geographic variations in the incidence of deliberate self-harm (DSH) and suicide have been shown to be associated with area-based measures of socio-economic deprivation and social fragmentation. Previous studies have been subject to methodological limitations. None has investigated whether ecological associa...

journal_title：Psychological medicine

authors： Hawton K,Harriss L,Hodder K,Simkin S,Gunnell D

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Certain personality traits predispose to criminal behavior (CB). We further clarify this relationship in a Swedish national sample. METHOD:Psychological strength (PS) was assessed on a nine-point scale at personal interview in 1 653 721 Swedish men aged 18-20 years. We examined the association between PS an...

journal_title：Psychological medicine

authors： Kendler KS,Lönn SL,Lichtenstein P,Sundquist J,Sundquist K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...

journal_title：Psychological medicine

authors： Docherty AR,Moscati A,Bigdeli TB,Edwards AC,Peterson RE,Adkins DE,Anderson JS,Flint J,Kendler KS,Bacanu SA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Previous research in resting-state functional magnetic resonance imaging (rs-fMRI) has shown a mixed pattern of disrupted thalamocortical connectivity in psychosis. The clinical meaning of these findings and their stability over time remains unclear. We aimed to study thalamocortical connectivity longitudina...

journal_title：Psychological medicine

authors： Bergé D,Lesh TA,Smucny J,Carter CS

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:The effects of antidepressants for treating depressive disorders have been overestimated because of selective publication of positive trials. Reanalyses that include unpublished trials have yielded reduced effect sizes. This in turn has led to claims that antidepressants have clinically insignificant advanta...

journal_title：Psychological medicine

authors： Cuijpers P,Turner EH,Mohr DC,Hofmann SG,Andersson G,Berking M,Coyne J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...

journal_title：Psychological medicine

authors： Kessler RC,Avenevoli S,McLaughlin KA,Green JG,Lakoma MD,Petukhova M,Pine DS,Sampson NA,Zaslavsky AM,Merikangas KR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Twenty states currently require that women seeking abortion be counseled on possible psychological responses, with six states stressing negative responses. The majority of research finds that women whose unwanted pregnancies end in abortion do not subsequently have adverse mental health outcomes; scant resea...

journal_title：Psychological medicine

authors： Gomez AM

更新日期：2018-01-01 00:00:00