Abstract:
:A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at least another seven had a subclinical form of the disorder during the six months prior to follow-up. Relapse into anorexia nervosa was uncommon, and the severity of the bulimic features had improved even among those still diagnosable as having the disorder. Affective disturbances were common among those who were bulimic. The findings were discussed in terms of the intermediate term outcome of the disorder and its identity as a clinical entity.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Hsu LK,Sobkiewicz TAdoi
10.1017/s0033291700005766subject
Has Abstractpub_date
1989-11-01 00:00:00pages
1035-8issue
4eissn
0033-2917issn
1469-8978journal_volume
19pub_type
杂志文章abstract:BACKGROUND:Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We investigated the predictions that older adults with ID should have...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708003334
更新日期:2009-01-01 00:00:00
abstract::The numbers of long-stay patients in Danish psychiatric hospitals were studied, based on information from the Danish cumulative psychiatric register and from the census studies of patients in Danish psychiatric hospitals, performed at 5-year intervals since 1957. In 1977, 2079 (20%) of the in-patient population which ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032116
更新日期:1979-08-01 00:00:00
abstract:BACKGROUND:Cigarette smoking is associated with worse cognition and decreased cortical volume and thickness in healthy cohorts. Chronic cigarette smoking is prevalent in schizophrenia spectrum disorders (SSD), but the effects of smoking status on the brain and cognition in SSD are not clear. This study aimed to underst...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005152
更新日期:2021-01-14 00:00:00
abstract::Lockdowns to control the spread of the coronavirus disease 2019 (COVID-19) have had profound effects on everyday life worldwide, but their effect on mental health remains unclear because available meta-analyses and reviews rely mostly on cross-sectional studies. We conducted a rapid review and meta-analysis of longitu...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291721000015
更新日期:2021-01-13 00:00:00
abstract:BACKGROUND:Preclinical and human studies suggest an association between chronic inflammation and the development of depressive behaviors. This is proposed to occur through downstream effects of inflammatory cytokines on neuroplasticity, neurogenesis and neurotransmitter function, although the neural correlates remain p...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002940
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Whether late-onset depression is a risk factor for or a prodrome of dementia remains unclear. We investigated the impact of depressive symptoms and early- v. late-onset depression on subsequent dementia in a cohort of elderly general-practitioner patients (n = 2663, mean age = 81.2 years). METHOD:Risk for s...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291712002449
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:The coronavirus [coronavirus disease 2019 (COVID-19)] pandemic has introduced extraordinary life changes and stress, particularly in adolescents and young adults. Initial reports suggest that depression and anxiety are elevated during COVID-19, but no prior study has explored changes at the within-person lev...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005358
更新日期:2021-01-13 00:00:00
abstract:BACKGROUND:The ability to appreciate humour is essential to successful human interactions. In this study, we hypothesized that individuals with schizophrenia would have diminished ability to recognize and appreciate humour. The relationship between humour experience and clinical symptoms, cognitive and social functioni...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002528
更新日期:2008-06-01 00:00:00
abstract::Platelet MAO activity was found to be elevated in primary depressive illness, and the severity to correlate positively with MAO activity. The reactive depression subgroup's mean platelet MAO activity was not significantly different from that of the controls. The endogenous group's unipolar and bipolar subgroups had si...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034048
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713002663
更新日期:2014-07-01 00:00:00
abstract::Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are post-synaptic receptors that are located in striatal and limbic areas known to be involved in cognition and mood. Consistent with this, 5-HT4 ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000604
更新日期:2020-04-03 00:00:00
abstract:BACKGROUND:Anxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physic...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712002504
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:With regard to current neurobiological theories, the aim of our study was to examine possible alterations of temporal and frontal lobe volume in panic disorder (PD). METHOD:Seventeen in-patients with PD and a group of healthy control subjects (HC) matched for age and gender were investigated by quantitative...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991930
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002718
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Alterations in self-monitoring have been reported in patients with psychotic disorders, but it remains unclear to what degree they represent true indicators of familial vulnerability for psychosis. METHOD:An error-correction action-monitoring task was used to examine self-monitoring in 42 patients with schi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711001152
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Assaultive violence events are associated with increased risk for adverse psychiatric outcomes, including post-traumatic stress (PTS), depression, and generalized anxiety. Prior research has indicated that economic, legal, and social stressors that could follow assaultive events may explain the increased ris...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717001143
更新日期:2017-10-01 00:00:00
abstract::In the literature on dementia the presence or absence of language deficits has come to occupy a pivotal position with respect to certain nosological and nosographical issues. These are reviewed critically, together with the results of experimental investigations which have sought to elucidate the nature of the languag...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291700001938
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Neurocognitive functioning may be impaired in the luteal phase of the menstrual cycle due to associated changes in hypothalamic-pituitary adrenal (HPA) axis function. This study examines the relationship between changes in neurocognition and HPA axis function in different phases of the menstrual cycle. METH...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291703008535
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291706009159
更新日期:2007-03-01 00:00:00
abstract::There are many reports which suggest that patients with effective illness (mania and/or depression) have abnormalities in the functioning of one or more neurobiological systems. At a conference convened by the Clinical Research Branch, Division of Extramural Research Programs, National Institute of Mental Health, thes...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700055057
更新日期:1980-11-01 00:00:00
abstract:BACKGROUND:Executive impairments have been reported in affective illness, but the influence of attention on executive performance has not been fully considered. The purpose of this study was to investigate whether executive impairments in affective illness were independent of attention impairments, and whether independ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707000712
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) leads to a significant decrease in CFS-related symptoms and disability. The primary objective of this study was to explore whether partners' solicitous responses and patients' and partners' perceived relationship satisfaction had an effect ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000288
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Meta-analyses link childhood trauma to depression, mania, anxiety disorders, and psychosis. It is unclear, however, whether these outcomes truly represent distinct disorders following childhood trauma, or that childhood trauma is associated with admixtures of affective, psychotic, anxiety and manic psychopat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714002372
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD:Data on age at onset, g...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004986
更新日期:2002-01-01 00:00:00
abstract::Sixty surviving patients from a community-based stroke register who had CT scan evidence of a single brain lesion and neurological signs appropriate to it were interviewed three to five years following their first-ever stroke. Mood disorder (anxiety and depression), physical disability, and intellectual impairment wer...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700036503
更新日期:1990-11-01 00:00:00
abstract::Increases in plasma noradrenaline were found in a group of 12 subjects smoking cigarettes. The associated rises in pulse rate, blood pressure and plasma free fatty acids could be prevented by beta-blockade with oxprenolol. This inhibition of the peripheral effects of catecholamines did not affect subjective satisfacti...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700013799
更新日期:1976-05-01 00:00:00
abstract::Major depressive disorder (MDD) is a mental illness with high socio-economic burden, but its pathophysiology has not been fully elucidated. Recently, the cortical excitatory and inhibitory imbalance hypothesis and neuroplasticity hypothesis have been proposed for MDD. Although several studies have examined the neuroph...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004729
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The significant proportion of schizophrenia patients refractory to treatment, primarily directed at the dopamine system, suggests that multiple mechanisms may underlie psychotic symptoms. Reinforcement learning tasks have been employed in schizophrenia to assess dopaminergic functioning and reward processing...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718000041
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Social capital has been considered aetiologically important in schizophrenia but the empirical evidence to support this hypothesis is absent. We tested whether social capital, measured at the neighbourhood level, was associated with the incidence of schizophrenia (ICD-10 F20). MethodWe administered a cross-s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002085
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Sleep disruption is a common precursor to deterioration and relapse in people living with psychotic disorders. Understanding the temporal relationship between sleep and psychopathology is important for identifying and developing interventions which target key variables that contribute to relapse. METHODS:We...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720004857
更新日期:2021-01-12 00:00:00