Plasma nortriptyline and clinical response--a study using changing plasma levels.

abstract：BACKGROUND:A number of scales are used to estimate the severity of depression. However, differences between self-report and clinician rating, multi-dimensionality and different weighting of individual symptoms in summed scores may affect the validity of measurement. In this study we examined and integrated the psychome...

journal_title：Psychological medicine

authors： Uher R,Farmer A,Maier W,Rietschel M,Hauser J,Marusic A,Mors O,Elkin A,Williamson RJ,Schmael C,Henigsberg N,Perez J,Mendlewicz J,Janzing JG,Zobel A,Skibinska M,Kozel D,Stamp AS,Bajs M,Placentino A,Barreto M,McGuf

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...

journal_title：Psychological medicine

authors： Dombrovski AY,Siegle GJ,Szanto K,Clark L,Reynolds CF,Aizenstein H

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Neuropsychological studies have suggested that memory systems reliant on medial temporal lobe structures are impaired in patients with depression. There is less data regarding whether this impairment is specific to recollection memory systems, and whether clinical features predict impairment. This study soug...

journal_title：Psychological medicine

authors： MacQueen GM,Galway TM,Hay J,Young LT,Joffe RT

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Almost nothing is known about the potential negative effects of Internet-based psychological treatments for depression. This study aims at investigating deterioration and its moderators within randomized trials on Internet-based guided self-help for adult depression, using an individual patient data meta-ana...

journal_title：Psychological medicine

authors： Ebert DD,Donkin L,Andersson G,Andrews G,Berger T,Carlbring P,Rozenthal A,Choi I,Laferton JA,Johansson R,Kleiboer A,Lange A,Lehr D,Reins JA,Funk B,Newby J,Perini S,Riper H,Ruwaard J,Sheeber L,Snoek FJ,Titov N,Ü

更新日期：2016-10-01 00:00:00

abstract：:Because of the potential importance of prolonged action neuroleptics for the delivery of care to schizophrenic patients, and because of the availability of new, extensive data from clinical trials on the utility of these drugs, a workshop conference was convened by the United States National Institute of Mental Health...

journal_title：Psychological medicine

authors： Levine J,Schooler NR,Cassano GB

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Bipolar disorder I (BD-I) is defined by episodes of mania, depression and euthymic states. These episodes are among other symptoms characterized by altered reward processing and negative symptoms (NS), in particular apathy. However, the neural correlates of these deficits are not well understood. METHODS:We...

journal_title：Psychological medicine

authors： Kirschner M,Cathomas F,Manoliu A,Habermeyer B,Simon JJ,Seifritz E,Tobler PN,Kaiser S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The present study tested the hypothesis of a differential pattern of reward and punishment responsiveness in depression measuring effort mobilization during anticipation and facial expressions during consumption. METHODS:Twenty patients with major depressive disorder (MDD) and 20 control participants worked...

journal_title：Psychological medicine

authors： Franzen J,Brinkmann K,Gendolla GHE,Sentissi O

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Cognitive behavioral therapy (CBT) can be delivered efficaciously through various modalities, including telephone (T-CBT) and face-to-face (FtF-CBT). The purpose of this study was to explore predictors of outcome in T-CBT and FtF-CBT for depression. METHOD:A total of 325 depressed participants were randomiz...

journal_title：Psychological medicine

authors： Stiles-Shields C,Corden ME,Kwasny MJ,Schueller SM,Mohr DC

更新日期：2015-11-01 00:00:00

abstract：:The powerful genome-wide association studies (GWAS) revealed common mutations that increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority were not known to be functional or associated with these illnesses. To help fill this gap, their impact on human brain structure and functio...

journal_title：Psychological medicine

authors： Gurung R,Prata DP

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The aims of the present study were to examine serum activities of peptidases, i.e. prolyl endopeptidase (PEP) and dipeptidyl peptidase IV (DPP IV), in patients with fibromyalgia and to examine the effects of subchronic treatment with sertraline on these variables. METHOD:Serum PEP and DPP IV activity were m...

journal_title：Psychological medicine

authors： Maes M,Libbrecht I,Van Hunsel F,Lin AH,Bonaccorso S,Goossens F,De Meester I,De Clerck L,Biondi M,Scharpe S,Janca A

更新日期：1998-07-01 00:00:00

abstract：:One hundred and nine adults were screened in the community using the abridged version of the CIDI (CIDIS). The subjects comprised DSM-III-R current cases (N = 48), lifetime cases (N = 31) and non-cases (N = 30). The interviews with the 109 subjects were conducted by one of two pairs of clinicians and videotaped. Each ...

journal_title：Psychological medicine

authors： Lesage AD,Fournier L,Cyr M,Toupin J,Fabian J,Gaudette G,Vanier C,Bebbington PE,Brewin CR

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:The differential strength of correlation between symptoms, cognition and other patient characteristics with community functioning in first-episode psychosis has not been fully investigated. METHOD:In a sample of 66 first-episode psychosis patients demographic variables, ratings of pre-morbid adjustment, pos...

journal_title：Psychological medicine

authors： Malla AK,Norman RM,Manchanda R,Townsend L

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Previous research in resting-state functional magnetic resonance imaging (rs-fMRI) has shown a mixed pattern of disrupted thalamocortical connectivity in psychosis. The clinical meaning of these findings and their stability over time remains unclear. We aimed to study thalamocortical connectivity longitudina...

journal_title：Psychological medicine

authors： Bergé D,Lesh TA,Smucny J,Carter CS

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:Cognitive remediation (CR) is an effective treatment for several psychiatric disorders. To date, there have been no published studies examining solely first-episode psychiatric cohorts, despite the merits demonstrated by early intervention CR studies. The current study aimed to assess the effectiveness of CR...

journal_title：Psychological medicine

authors： Lee RS,Redoblado-Hodge MA,Naismith SL,Hermens DF,Porter MA,Hickie IB

更新日期：2013-06-01 00:00:00

abstract：:The examination of moment-to-moment, 'micro-level' patterns of experience and behaviour using experience sampling methodology has contributed to our understanding of the 'macro-level' development of full-blown symptoms and disorders. This paper argues that the micro-level perspective can be used to identify the smalle...

journal_title：Psychological medicine

authors： Wichers M

更新日期：2014-05-01 00:00:00

abstract：:A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...

journal_title：Psychological medicine

authors： Hsu LK,Sobkiewicz TA

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Many preschool-age children meet criteria for psychiatric disorders, and rates approach those observed in later childhood and adolescence. However, there is a paucity of longitudinal research examining the outcomes of preschool diagnoses. METHODS:Families with a 3-year-old child (N = 559) were recruited fro...

journal_title：Psychological medicine

authors： Finsaas MC,Bufferd SJ,Dougherty LR,Carlson GA,Klein DN

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Several case reports and reviews have suggested an increased incidence of schizophrenia or bipolar disorder among persons with sex chromosome aneuploidies, but this observation may have been caused by biased sampling. METHODS:The 1122 individuals with sex chromosome aneuploidies registered in the Danish Cyt...

journal_title：Psychological medicine

authors： Mors O,Mortensen PB,Ewald H

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Both low intelligence and low emotional control have previously been linked to a higher risk of suicide, but it is unknown whether the associations apply consistently over the life course. METHODS:The study was based on data on intelligence and emotional control, collected from 48 738 Swedish men conscripte...

journal_title：Psychological medicine

authors： Hansson Bittár N,Falkstedt D,Sörberg Wallin A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Social disadvantage consistently predicts both self-reported distress and clinically diagnosed disorders such as depression. Yet, many individuals who are exposed to disadvantage do not report high levels of distress. This study extends our recent work showing that high cognitive ability may protect against ...

journal_title：Psychological medicine

authors： Bridger E,Daly M

更新日期：2019-07-01 00:00:00

abstract：:Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...

journal_title：Psychological medicine

authors： Tennant C,Goulston K,Dent O

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The output of many healthy physiological systems displays fractal fluctuations with self-similar temporal structures. Altered fractal patterns are associated with pathological conditions. There is evidence that patients with bipolar disorder have altered daily behaviors. METHODS:To test whether fractal patt...

journal_title：Psychological medicine

authors： Knapen SE,Li P,Riemersma-van der Lek RF,Verkooijen S,Boks MPM,Schoevers RA,Scheer FAJL,Hu K

更新日期：2020-04-01 00:00:00

abstract：:Data from a general population survey of psychiatric disorder in Camberwell were used to calculate the risk of a CATEGO-defined depressive episode before the age of 65, using a modification of Strömgren's method. Current depression was defined as cases within the relevant categories of the CATEGO program and at thresh...

journal_title：Psychological medicine

authors： Bebbington P,Katz R,McGuffin P,Tennant C,Hurry J

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...

journal_title：Psychological medicine

authors： Winsper C,Zanarini M,Wolke D

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Although attention deficit hyperactivity disorder (ADHD) and bipolar disorder (BPD) co-occur frequently and represent a particularly morbid clinical form of both disorders, neuroimaging research addressing this co-morbidity is scarce. Our aim was to evaluate the morphometric magnetic resonance imaging (MRI) ...

journal_title：Psychological medicine

authors： Biederman J,Makris N,Valera EM,Monuteaux MC,Goldstein JM,Buka S,Boriel DL,Bandyopadhyay S,Kennedy DN,Caviness VS,Bush G,Aleardi M,Hammerness P,Faraone SV,Seidman LJ

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...

journal_title：Psychological medicine

authors： Shang CY,Gau SS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The aim of the study was to determinate whether schizophrenia patients with a history of cannabis use have a different prognosis, with regards to readmission and hospital duration, compared with those without a history of cannabis use. METHOD:The present investigation was a cohort study of 50,087 Swedish me...

journal_title：Psychological medicine

authors： Manrique-Garcia E,Zammit S,Dalman C,Hemmingsson T,Andreasson S,Allebeck P

更新日期：2014-09-01 00:00:00

abstract：:Long-stay patients who were discharged from Friern and Claybury hospitals during the 6-year period between September 1985 and August 1991 were followed up for at least 1 year and the details of all readmissions were recorded. Of the 615 hospital leavers, some 178 (29%) were readmitted at some time during the follow-up...

journal_title：Psychological medicine

authors： Gooch C,Leff J

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM...

journal_title：Psychological medicine

authors： Hargreaves A,Anney R,O'Dushlaine C,Nicodemus KK,Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ).,Wellcome Trust Case Control Consortium 2.,Gill M,Corvin A,Morris D,Donohoe G

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Subjects at 'ultra high risk' (UHR) for developing psychosis have differences in white matter (WM) compared with healthy controls. WM integrity has not yet been investigated in UHR subjects in relation to the development of subsequent psychosis. Hence, we investigated a prospective cohort of UHR subjects com...

journal_title：Psychological medicine

authors： Bloemen OJ,de Koning MB,Schmitz N,Nieman DH,Becker HE,de Haan L,Dingemans P,Linszen DH,van Amelsvoort TA

更新日期：2010-08-01 00:00:00