Preschool psychiatric disorders: homotypic and heterotypic continuity through middle childhood and early adolescence.

abstract：BACKGROUND:Factor analysis has been employed to identify latent variables that are unifying constructs and that parsimoniously describe correlations among a related group of variables. Confirmatory factor analysis is used to test hypothesized factor structures for a set of variables; it can also, as in this paper be us...

journal_title：Psychological medicine

authors： Jacob KS,Everitt BS,Patel V,Weich S,Araya R,Lewis GH

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Classification of psychosis lacks a biological basis and current diagnostic categories may obscure underlying continuities. Data reduction methods of symptom profiles within a population-based cohort of people with a wide range of affective and non-affective psychoses may permit an empirical classification o...

journal_title：Psychological medicine

authors： Murray V,McKee I,Miller PM,Young D,Muir WJ,Pelosi AJ,Blackwood DH

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:A long-standing issue in the health anxiety literature is the extent to which health anxiety is a dimensional or a categorical construct. This study explores this question directly using taxometric procedures. METHOD:Seven hundred and eleven working adults completed an index of health anxiety [the Whiteley ...

journal_title：Psychological medicine

authors： Ferguson E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Executive impairments have been reported in affective illness, but the influence of attention on executive performance has not been fully considered. The purpose of this study was to investigate whether executive impairments in affective illness were independent of attention impairments, and whether independ...

journal_title：Psychological medicine

authors： Stoddart SD,Craddock NJ,Jones LA

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Studies suggest that alcohol consumption and alcohol use disorders have distinct genetic backgrounds. METHODS:We examined whether polygenic risk scores (PRS) for consumption and problem subscales of the Alcohol Use Disorders Identification Test (AUDIT-C, AUDIT-P) in the UK Biobank (UKB; N = 121 630) correla...

journal_title：Psychological medicine

authors： Johnson EC,Sanchez-Roige S,Acion L,Adams MJ,Bucholz KK,Chan G,Chao MJ,Chorlian DB,Dick DM,Edenberg HJ,Foroud T,Hayward C,Heron J,Hesselbrock V,Hickman M,Kendler KS,Kinreich S,Kramer J,Kuo SI,Kuperman S,Lai D,McI

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Strategies to dissect phenotypic and genetic heterogeneity of major depressive disorder (MDD) have mainly relied on subphenotypes, such as age at onset (AAO) and recurrence/episodicity. Yet, evidence on whether these subphenotypes are familial or heritable is scarce. The aims of this study are to investigate...

journal_title：Psychological medicine

authors： Ferentinos P,Koukounari A,Power R,Rivera M,Uher R,Craddock N,Owen MJ,Korszun A,Jones L,Jones I,Gill M,Rice JP,Ising M,Maier W,Mors O,Rietschel M,Preisig M,Binder EB,Aitchison KJ,Mendlewicz J,Souery D,Hauser J,

更新日期：2015-07-01 00:00:00

abstract：:Neuropsychological tests of frontal lobe functions were undertaken in 46 chronic schizophrenic patients who were also rated for movement disorders. Tardive dyskinesia was found to have significant associations with most of these psychological tests. The possible mechanisms are discussed within the context of known neo...

journal_title：Psychological medicine

authors： Brown KW,White T,Palmer D

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Previous research has established the relationship between cannabis use and psychotic disorders. Whether cannabis use is related to transition to psychosis in patients at ultra-high risk (UHR) for psychosis remains unclear. The present study aimed to review the existing evidence on the association between ca...

journal_title：Psychological medicine

authors： Kraan T,Velthorst E,Koenders L,Zwaart K,Ising HK,van den Berg D,de Haan L,van der Gaag M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Several studies during recent years have reported an increased occurrence of schizophrenia in selected immigrant groups. However, difficulties in establishing the population denominator for immigrant rates of mental disorder, selective referral for treatment, and other problems may have influenced such resul...

journal_title：Psychological medicine

authors： Mortensen PB,Cantor-Graae E,McNeil TF

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:This two-stage prevalence survey involved geographically delimited areas, four urban (Liverpool, Newcastle, Nottingham and Oxford) and two rural (Cambridgeshire and Gwynedd), including institutions. METHODS:Stratified random population samples of people in their 65th year and above, from Family Health Servi...

journal_title：Psychological medicine

authors：

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Few large studies describe links between maternal mental illness and risk of major birth defect in offspring. Evidence is sparser still for how effects vary between maternal diagnoses and no previous study has assessed risk with paternal illnesses. METHOD:A population-based birth cohort was created by linki...

journal_title：Psychological medicine

authors： Webb RT,Pickles AR,King-Hele SA,Appleby L,Mortensen PB,Abel KM

更新日期：2008-10-01 00:00:00

abstract：:The examination of moment-to-moment, 'micro-level' patterns of experience and behaviour using experience sampling methodology has contributed to our understanding of the 'macro-level' development of full-blown symptoms and disorders. This paper argues that the micro-level perspective can be used to identify the smalle...

journal_title：Psychological medicine

authors： Wichers M

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Cognitive theory points to the importance of negative self-schemas in the onset and maintenance of depression and anxiety disorders. Hereby, it is important to distinguish between automatic and explicit self-schemas, reflecting different cognitive-motivational systems. This study tested whether patients with...

journal_title：Psychological medicine

authors： Glashouwer KA,de Jong PJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Different versions of the General Health Questionnaire (GHQ), including the GHQ-12 and GHQ-28 have been subjected to factor analysis in a variety of countries. The World Health Organization study of psychological disorders in general health care offered the opportunity to investigate the factor structure of ...

journal_title：Psychological medicine

authors： Werneke U,Goldberg DP,Yalcin I,Ustün BT

更新日期：2000-07-01 00:00:00

abstract：:Parental representation was assessed with the Parental Bonding Instrument (PBI) in 12 monozygotic (MZ) and 19 dizygotic (DZ) same-sexed twin pairs discordant for DSM-III-R schizophrenia. The schizophrenic twins reported less care and more overprotection from both parents than the non-schizophrenic co-twins. Multiple r...

journal_title：Psychological medicine

authors： Onstad S,Skre I,Torgersen S,Kringlen E

更新日期：1993-05-01 00:00:00

abstract：:The relationships among symptoms, cognitive functioning and social functioning were investigated in 60 patients with recent-onset schizophrenia. Positive symptoms were unrelated to cognitive measures. Disorganization and depressive symptoms were correlated significantly with Card Sorting performance. Furthermore, only...

journal_title：Psychological medicine

authors： Van der Does AJ,Dingemans PM,Linszen DH,Nugter MA,Scholte WF

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:There is evidence that cannabis use might be relevant to the aetiology of schizophrenia. We aimed to measure any change in cannabis use over time in those first presenting with schizophrenia in South-East London from 1965 to 1999, and compare this with change in use in those presenting with non-psychotic psy...

journal_title：Psychological medicine

authors： Boydell J,van Os J,Caspi A,Kennedy N,Giouroukou E,Fearon P,Farrell M,Murray RM

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:To provide an overview of epidemiological studies of dementia among migrant groups in Europe and to estimate their pooled odds ratio (OR) v. the reference population. METHODS:Search for articles reporting on incidence or prevalence of dementia among ethnic minorities and migrants in Europe, published before...

journal_title：Psychological medicine

authors： Selten JP,Termorshuizen F,van Sonsbeek M,Bogers J,Schmand B

更新日期：2020-04-08 00:00:00

abstract：:A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observat...

journal_title：Psychological medicine

authors： Weller MP,Latimer-Sayer DT

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Advanced paternal age is associated with increased risk of schizophrenia. This study aimed to explore whether older paternal age is associated with earlier onset among co-affected schizophrenia sib-pairs with the same familial predisposition. METHOD:A total of 1297 patients with schizophrenia from 630 famil...

journal_title：Psychological medicine

authors： Wang SH,Liu CM,Hwu HG,Hsiao CK,Chen WJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:This study seeks to clarify the contribution of temporally stable and occasion-specific genetic and environmental influences on risk for major depression (MD). METHOD:Our sample was 2153 members of female-female twin pairs from the Virginia Twin Registry. We examined four personal interview waves conducted ...

journal_title：Psychological medicine

authors： Kendler KS,Gardner CO

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...

journal_title：Psychological medicine

authors： Laskemoen JF,Aas M,Vaskinn A,Berg AO,Lunding SH,Barrett EA,Melle I,Simonsen C

更新日期：2020-04-23 00:00:00

abstract：BACKGROUND:Although alcohol use disorder (AUD) is associated with future risk for psychosocial dysfunction, the degree to which this arises from a direct causal effect of AUD on functioning v. from correlated risk factors (also known as confounders) is less clearly established. METHOD:AUD was assessed from Swedish med...

journal_title：Psychological medicine

authors： Kendler KS,Ohlsson H,Karriker-Jaffe KJ,Sundquist J,Sundquist K

更新日期：2017-04-01 00:00:00

abstract：:Because of the potential importance of prolonged action neuroleptics for the delivery of care to schizophrenic patients, and because of the availability of new, extensive data from clinical trials on the utility of these drugs, a workshop conference was convened by the United States National Institute of Mental Health...

journal_title：Psychological medicine

authors： Levine J,Schooler NR,Cassano GB

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Psychological traumatic events, such as war or road traffic accidents, are widespread. A small but significant proportion of survivors develop post-traumatic stress disorder (PTSD). Distressing, sensory-based involuntary memories of trauma (henceforth 'flashbacks') are the hallmark symptom of PTSD. Understan...

journal_title：Psychological medicine

authors： Bourne C,Mackay CE,Holmes EA

更新日期：2013-07-01 00:00:00

abstract：:Messenger RNA (mRNA) is the key intermediate in the gene expression pathway. The amount of mRNA in Alzheimer's disease (AD) brains has been determined using in situ hybridization histochemistry (ISHH) to detect the poly(A) tails of polyadenylated mRNA (poly(A) + mRNA). On a regional basis, AD cases had significantly l...

journal_title：Psychological medicine

authors： Harrison PJ,Barton AJ,Najlerahim A,McDonald B,Pearson RC

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Previous studies have highlighted the role of the brain reward and cognitive control systems in the etiology of anorexia nervosa (AN). In an attempt to disentangle the relative contribution of these systems to the disorder, we used functional magnetic resonance imaging (fMRI) to investigate hemodynamic respo...

journal_title：Psychological medicine

authors： Boehm I,King JA,Bernardoni F,Geisler D,Seidel M,Ritschel F,Goschke T,Haynes JD,Roessner V,Ehrlich S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Abnormal perceptions of food and shape underpin the cognitive behavioural model of eating disorders (EDs). The aim of this study was to investigate motivational processing of disorder-specific and standard emotional cues in anorexia (AN) and bulimia nervosa (BN) using startle eyeblink modulation (SEM). SEM w...

journal_title：Psychological medicine

authors： Friederich HC,Kumari V,Uher R,Riga M,Schmidt U,Campbell IC,Herzog W,Treasure J

更新日期：2006-09-01 00:00:00

abstract：:The numbers of long-stay patients in Danish psychiatric hospitals were studied, based on information from the Danish cumulative psychiatric register and from the census studies of patients in Danish psychiatric hospitals, performed at 5-year intervals since 1957. In 1977, 2079 (20%) of the in-patient population which ...

journal_title：Psychological medicine

authors： Weeke A,Kastrup M,Dupont A

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiop...

journal_title：Psychological medicine

authors： Zammit S,Odd D,Horwood J,Thompson A,Thomas K,Menezes P,Gunnell D,Hollis C,Wolke D,Lewis G,Harrison G

更新日期：2009-09-01 00:00:00