Regional and neuronal reductions of polyadenylated messenger RNA in Alzheimer's disease.

abstract：BACKGROUND:High expressed emotion (EE) in families reliably predicts relapse in schizophrenia leading to the assumption that high EE stresses patients and is the cause of relapse. Attempts at validating the stressful properties of high EE using autonomic skin conductance measures have been inconclusive. Since memory lo...

journal_title：Psychological medicine

authors： Dixon MJ,King S,Stip E,Cormier H

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Meta-analyses support the efficacy of cognitive-behavioural therapy (CBT) for schizophrenia in western cultures. This study aimed to compare the efficacy of CBT and supportive therapy (ST) for patients with schizophrenia in China. METHOD:A multicentre randomized controlled, single-blinded, parallel-group tr...

journal_title：Psychological medicine

authors： Li ZJ,Guo ZH,Wang N,Xu ZY,Qu Y,Wang XQ,Sun J,Yan LQ,Ng RM,Turkington D,Kingdon D

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that depressed patients are impaired in their ability to shift attention from one emotional category to another, but whether this shifting deficit is more evident ...

journal_title：Psychological medicine

authors： Murphy FC,Michael A,Sahakian BJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Patients with anorexia nervosa (AN) run a high risk of becoming chronically ill and of dying. In the acute phase of their illness they present with numerous physical and laboratory abnormalities. However, little is known about the long-term prognostic value of these findings or about the medical morbidity in...

journal_title：Psychological medicine

authors： Herzog W,Deter HC,Fiehn W,Petzold E

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Little is known about the association of eating disorder subtypes across multiple categories of substance use in population-based samples. We examined the association between eating disorders and substance use in a large population-based sample. METHOD:Female participants (n=13 297) were from the Swedish Tw...

journal_title：Psychological medicine

authors： Root TL,Pisetsky EM,Thornton L,Lichtenstein P,Pedersen NL,Bulik CM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Studies investigating early developmental factors in relation to psychopathology have mainly focused on schizophrenia. The personality dimension of neuroticism seems to be a general risk factor for psychopathology, but evidence on associations between early developmental precursors and personality traits is ...

journal_title：Psychological medicine

authors： Flensborg-Madsen T,Sørensen HJ,Revsbech R,Mortensen EL

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Psychological traumatic events, such as war or road traffic accidents, are widespread. A small but significant proportion of survivors develop post-traumatic stress disorder (PTSD). Distressing, sensory-based involuntary memories of trauma (henceforth 'flashbacks') are the hallmark symptom of PTSD. Understan...

journal_title：Psychological medicine

authors： Bourne C,Mackay CE,Holmes EA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:A dysfunctional network of prefrontal and (para-)limbic brain region has been suggested to underlie emotional dysregulation in borderline personality disorder (BPD). Abnormal activity in this network may be due to structural alterations in white-matter tracts connecting prefrontal and (para-)limbic brain reg...

journal_title：Psychological medicine

authors： Lischke A,Domin M,Freyberger HJ,Grabe HJ,Mentel R,Bernheim D,Lotze M

更新日期：2015-11-01 00:00:00

abstract：:This is a study of the criterion validity of a newly developed computerized assessment (PROQSY) of minor psychological morbidity based on the Clinical Interview Schedule, employing a single GP's assessments as criterion measures of such morbidity and Relative Operating Characteristic (ROC) analysis. Two-stage screenin...

journal_title：Psychological medicine

authors： Wilkinson G,Markus AC

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Understanding the pathways to psychiatric care and recognition of delay points are crucial for the development of interventions that aim to improve access to mental health-care services. METHOD:Over a 2-month period in 2003, a total of 1044 patients at the commencement of new episodes of care at Amanuel Spe...

journal_title：Psychological medicine

authors： Bekele YY,Flisher AJ,Alem A,Baheretebeb Y

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:The clinical picture of schizophrenia is frequently worsened by manifestations of impulsivity. However, the neural correlates of impulsivity in this disorder are poorly known. Although impulsivity has been related to disturbances of the neural processes underlying response inhibition, no studies have yet exa...

journal_title：Psychological medicine

authors： Kaladjian A,Jeanningros R,Azorin JM,Anton JL,Mazzola-Pomietto P

更新日期：2011-02-01 00:00:00

abstract：:Monthly hospital admission rates (HA) for mania were classified by sex, type of admission (first, or re-admission) and by country (England and Wales or Scotland). Of the 8 classes thus created, all but one showed a statistically significant annual cycle with a peak in Summer and trough in Winter. There was no signific...

journal_title：Psychological medicine

authors： Myers DH,Davies P

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Aggressive behaviour is increased among those with schizophrenia but less is known about those with affective psychoses. Similarly, little is known about aggressive behaviour occurring at the onset of illness. METHOD:The main reasons for presentation to services were examined among those recruited to a UK-b...

journal_title：Psychological medicine

authors： Dean K,Walsh E,Morgan C,Demjaha A,Dazzan P,Morgan K,Lloyd T,Fearon P,Jones PB,Murray RM

更新日期：2007-04-01 00:00:00

abstract：:A non-recursive structural equation model designed to examine the reciprocal relationship between life event reports and depressive symptoms in women is presented. The model was fitted to data from a 2-year longitudinal study of life events and depression in a sample of women with 5-year-old children. The findings sug...

journal_title：Psychological medicine

authors： Fergusson DM,Horwood LJ

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Outcome studies of chronic fatigue, neurasthenia and other unexplained fatigue syndromes are few and have been carried out in developed Western countries. This paper aimed to study the outcome of unexplained fatigue syndromes in an international primary care sample and to identify risk factors for persistenc...

journal_title：Psychological medicine

authors： Skapinakis P,Lewis G,Mavreas V

更新日期：2003-07-01 00:00:00

abstract：:The psychiatric status of patients with chronic fatigue syndrome (N = 34) and muscle disease (N = 24) attending a general medical clinic was studied. Among fatigue patients 14 (41.2%) were cases and a further 9 (26.5%) were subcases of psychiatric disorder as defined by CATEGO. A variety of diagnoses was found. Signif...

journal_title：Psychological medicine

authors： Wood GC,Bentall RP,Göpfert M,Edwards RH

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Research suggests that the personality factor of self-critical or maladaptive perfectionism may be implicated in chronic fatigue syndrome (CFS). However, it is not clear whether self-critical perfectionism (SCP) also predicts daily symptoms in CFS. Method In the present study we investigated whether SCP pred...

journal_title：Psychological medicine

authors： Kempke S,Luyten P,Claes S,Goossens L,Bekaert P,Van Wambeke P,Van Houdenhove B

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:To provide an overview of epidemiological studies of dementia among migrant groups in Europe and to estimate their pooled odds ratio (OR) v. the reference population. METHODS:Search for articles reporting on incidence or prevalence of dementia among ethnic minorities and migrants in Europe, published before...

journal_title：Psychological medicine

authors： Selten JP,Termorshuizen F,van Sonsbeek M,Bogers J,Schmand B

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:As children with attention-deficit/hyperactivity disorder (ADHD) usually show psychopathological signs beyond their core symptoms (e.g. elevated scores of the dysregulation profile (DP) in 30-40%), treatments with a broader approach to self-regulation skills may be supportive. Neurofeedback (NF) may reflect ...

journal_title：Psychological medicine

authors： Heinrich H,Gevensleben H,Becker A,Rothenberger A

更新日期：2020-01-01 00:00:00

abstract：:Lockdowns to control the spread of the coronavirus disease 2019 (COVID-19) have had profound effects on everyday life worldwide, but their effect on mental health remains unclear because available meta-analyses and reviews rely mostly on cross-sectional studies. We conducted a rapid review and meta-analysis of longitu...

journal_title：Psychological medicine

authors： Prati G,Mancini AD

更新日期：2021-01-13 00:00:00

abstract：:The tests that have been used to assess glomerular and tubular function in patients receiving treatment with lithium have been reviewed. The advantages and disadvantages of these are discussed. The most useful tests are the creatinine clearance, which may be predicted from the serum creatinine using a formula or nomog...

journal_title：Psychological medicine

authors： Waller DG,Edwards JG

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Advanced paternal age is associated with increased risk of schizophrenia. This study aimed to explore whether older paternal age is associated with earlier onset among co-affected schizophrenia sib-pairs with the same familial predisposition. METHOD:A total of 1297 patients with schizophrenia from 630 famil...

journal_title：Psychological medicine

authors： Wang SH,Liu CM,Hwu HG,Hsiao CK,Chen WJ

更新日期：2015-07-01 00:00:00

abstract：:The Geriatric Mental State and a new computerized diagnostic system, AGECAT, are briefly described. A nomenclature for designating cases for epidemiological work is introduced. Concordance between AGECAT and psychiatrists' diagnoses for these studies, hospital and community based (total of 541 subjects), achieved over...

journal_title：Psychological medicine

authors： Copeland JR,Dewey ME,Griffiths-Jones HM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), com...

journal_title：Psychological medicine

authors： Roberge P,Provencher MD,Gaboury I,Gosselin P,Vasiliadis HM,Benoît A,Carrier N,Antony MM,Chaillet N,Houle J,Hudon C,Norton PJ

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Parental characteristics and practices predict borderline personality disorder (BPD) symptoms in children. However, it is difficult to disentangle whether these effects are genetically or environmentally mediated. The present study examines the contributions of genetic and environmental influences by compari...

journal_title：Psychological medicine

authors： Fatimah H,Wiernik BM,Gorey C,McGue M,Iacono WG,Bornovalova MA

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Working memory (WM) deficits in schizophrenia (SCZ) have been linked to impairments in the encoding phase that are associated with aberrant neuronal functioning. Similar abnormalities have been observed in unaffected first-degree relatives (REL) and are thus discussed as candidate endophenotypes. The process...

journal_title：Psychological medicine

authors： Stäblein M,Storchak H,Ghinea D,Kraft D,Knöchel C,Prvulovic D,Bittner RA,Reif A,Oertel-Knöchel V

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Patients may present with cognitive impairment in the euthymic phase of affective disorder, but it is unclear whether the impairment is prevalent before onset of the illness. The aim of the present study was to examine the hypothesis that genetic liability to affective disorder is associated with cognitive i...

journal_title：Psychological medicine

authors： Christensen MV,Kyvik KO,Kessing LV

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Mild traumatic brain injury (mTBI) is being claimed as the 'signature' injury of the Iraq war, and is believed to be the cause of long-term symptomatic ill health (post-concussional syndrome; PCS) in an unknown proportion of military personnel. METHOD:We analysed cross-sectional data from a large, randomly ...

journal_title：Psychological medicine

authors： Fear NT,Jones E,Groom M,Greenberg N,Hull L,Hodgetts TJ,Wessely S

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Studies investigating neurocognitive impairment in subjects with eating disorders (EDs) have reported heterogeneous patterns of impairment and, in some instances, no dysfunction. The present study aimed to define the pattern of neurocognitive impairment in a large sample of bulimia nervosa (BN) patients and ...

journal_title：Psychological medicine

authors： Galderisi S,Bucci P,Mucci A,Bellodi L,Cassano GB,Santonastaso P,Erzegovesi S,Favaro A,Mauri M,Monteleone P,Maj M

更新日期：2011-04-01 00:00:00

abstract：:The diversity of research methods applied to psychiatric disorders results in a confusing plethora of causal claims. To help make sense of these claims, the interventionist model (IM) of causality has several attractive features. First, it connects causation with the practical interests of psychiatry, defining causati...

journal_title：Psychological medicine

authors： Kendler KS,Campbell J

更新日期：2009-06-01 00:00:00