Abstract:
:The relationships among symptoms, cognitive functioning and social functioning were investigated in 60 patients with recent-onset schizophrenia. Positive symptoms were unrelated to cognitive measures. Disorganization and depressive symptoms were correlated significantly with Card Sorting performance. Furthermore, only negative symptoms were correlated significantly with social functioning. These results replicate earlier studies with chronic and mixed samples, and support the validity of disorganization as a separate symptom dimension. In contrast to most previous studies, no significant correlations were found between negative symptoms and cognitive measures. However, some evidence was found for a non-linear association between negative symptoms had several cognitive measures. The variation explained by a curvilinear model was not high, but for some cognitive measures this model was clearly superior to a linear model. If replicated, this finding supports the position that cross-sectionally measured negative symptoms cannot be viewed as a unitary concept.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Van der Does AJ,Dingemans PM,Linszen DH,Nugter MA,Scholte WFdoi
10.1017/s0033291700025514subject
Has Abstractpub_date
1993-08-01 00:00:00pages
745-53issue
3eissn
0033-2917issn
1469-8978journal_volume
23pub_type
杂志文章abstract:OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704003319
更新日期:2005-02-01 00:00:00
abstract::The incidence of cavum septum pellucidum (CSP), which has been widely regarded as a developmental anomaly of little clinical importance in neuropathology, was examined in 113 patients with affective disorders (69 with bipolar disorder and 44 with major depression), 40 schizophrenic patients, and 92 control subjects by...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034838
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Women's vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This ...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291714002773
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712000025
更新日期:2012-09-01 00:00:00
abstract::One hundred and sixteen working-class housewives, part-time and full-time employees were compared on a range of well-being measures in three different lifestages. A group of factory employees was contrasted with a 'mixed occupation' group for a comparison of type of employment. The general contention that the associat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700034978
更新日期:1995-07-01 00:00:00
abstract::Individuals with high and low susceptibility to hypnosis were compared in a baseline condition and after instructions of hypnosis on tests of anterior left and right hemispheric functions--word fluency to letter categories, word fluency to semantic categories, design fluency and bilateral finger tapping dexterity. Wit...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s0033291700038885
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Subthreshold depression is a highly prevalent condition and a risk factor for developing a major depressive episode. Internet-based cognitive behaviour therapy may be a promising approach for the treatment of subthreshold depression. The current study had two aims: (1) to determine whether an internet-based ...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291707000542
更新日期:2007-12-01 00:00:00
abstract::This study examined the relationship between personality factors and depression in subjects who may have a familial vulnerability to depression (i.e. first-degree relatives of depressed patients). Four groups comprised our study sample: relatives who had never experienced a psychiatric episode of depression; relatives...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700013052
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:Both low intelligence and low emotional control have previously been linked to a higher risk of suicide, but it is unknown whether the associations apply consistently over the life course. METHODS:The study was based on data on intelligence and emotional control, collected from 48 738 Swedish men conscripte...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002423
更新日期:2020-10-01 00:00:00
abstract::Seventy-six women, with a mean age of 35.7 years, who reported premenstrual craving for sweet foods in a retrospective questionnaire, were assessed prospectively with a pre- and post-menstrual eating questionnaire and daily ratings of craving, mood, irritability and breast tenderness over two menstrual cycles. In 72% ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170000979x
更新日期:1988-11-01 00:00:00
abstract::A survey over 2 years of all Police Referrals (Section 136 of the Mental Health Act 1983) in an inner-city health district identified 163 cases, with a core group of repeat referrals. Previous psychiatric admissions, a diagnosis of schizophrenia, social deprivation, and a bias towards young men of Afro-Caribbean ethni...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700038204
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Hierarchical structural models of psychopathology rarely extend to obsessive-compulsive spectrum disorders. The current study sought to examine the higher-order structure of the obsessive-compulsive and related disorders (OCRDs) in DSM-5: obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysm...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000380
更新日期:2020-03-06 00:00:00
abstract:BACKGROUND:Attention deficit hyperactivity disorder (ADHD) shows a strong phenotypic and genetic association with reaction time (RT) variability, considered to reflect lapses in attention. Yet we know little about whether this aetiological pathway is shared with other affected cognitive processes in ADHD, such as lower...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170999119X
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Schizophrenia is associated with perceptual organization deficits and abnormal neuronal connectivity has been described in early visual areas. The purpose of this study was to investigate the functional integrity of lateral connections in early visual areas of patients with schizophrenia and type I bipolar d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291705004381
更新日期:2005-07-01 00:00:00
abstract::Brown and his colleagues have presented evidence for the social origins of depression from results of 2 community surveys in Camberwell. This paper examines critically their methodology, conceptualization of variables, mode of argument and statistical techniques. Log-linear analysis of their published data fails to su...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170001878x
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study ...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291712000244
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707001080
更新日期:2007-11-01 00:00:00
abstract::Schizophrenia and affective disorders selected according to the Feighner criteria can be differentiated on the basis of 40-year outcome. Within schizophrenia the presence of disorganized thoughts at the index admission was associated with poor outcome, whereas better outcome was associated with the presence of delusio...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700052107
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND:Studies investigating neurocognitive impairment in subjects with eating disorders (EDs) have reported heterogeneous patterns of impairment and, in some instances, no dysfunction. The present study aimed to define the pattern of neurocognitive impairment in a large sample of bulimia nervosa (BN) patients and ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710001303
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Hypochondriasis is recognized as an important disorder in clinical populations, associated with increased health care utilization, disability and psychiatric co-morbidity. Few studies have investigated hypochondriasis in the community. We report on the broader concept of illness worry in a community populati...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701003737
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Civilian suicide rates vary by occupation in ways related to occupational stress exposure. Comparable military research finds suicide rates elevated in combat arms occupations. However, no research has evaluated variation in this pattern by deployment history, the indicator of occupation stress widely consid...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715001294
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Childhood abuse is a risk factor for poorer illness course in bipolar disorder, but the reasons why are unclear. Trait-like features such as affective instability and impulsivity could be part of the explanation. We aimed to examine whether childhood abuse was associated with clinical features of bipolar dis...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002411
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Pre- and perinatal adversities may increase the risk for schizophrenia and bipolar disorder. Hypoxia-related obstetric complications (OCs) are associated with brain anatomical abnormalities in schizophrenia, but their association with brain anatomy variation in bipolar disorder is unknown. METHOD:Magnetic r...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001529
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Few large studies describe links between maternal mental illness and risk of major birth defect in offspring. Evidence is sparser still for how effects vary between maternal diagnoses and no previous study has assessed risk with paternal illnesses. METHOD:A population-based birth cohort was created by linki...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707002280
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Alterations in self-monitoring have been reported in patients with psychotic disorders, but it remains unclear to what degree they represent true indicators of familial vulnerability for psychosis. METHOD:An error-correction action-monitoring task was used to examine self-monitoring in 42 patients with schi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711001152
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:This study examined two competing hypotheses concerning the association between diabetes and treatment for depression: (1) the detection/ascertainment bias hypothesis suggesting that those with diabetes are more likely to be diagnosed with and treated for depression because of increased medical attention and...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713001566
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Several conceptual models have been considered for the assessment of personality pathology in DSM-5. This study sought to extend our previous findings to compare the long-term predictive validity of three such models: the five-factor model (FFM), the schedule for nonadaptive and adaptive personality (SNAP), ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002601
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Although the traditional view of bipolar affective disorder is that the majority of patients have full remission between episodes, recent evidence suggests that residual cognitive deficits are present. The aim of this study was to determine whether memory and executive deficits were present in a well-defined...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799002664
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713002663
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:The aims of this study were to examine the associations between exposure to unemployment following school leaving and rates of psychiatric disorder using data gathered on a birth cohort of New Zealand young people studied up to the age of 18. METHODS:At age 18 cohort members were assessed on: (a) duration o...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291796004412
更新日期:1997-03-01 00:00:00