Abstract:
:Twenty schizophrenic patients with tardive dyskinesia and an equal number of matched controls were tested on a novel cognitive task. The task had two components: cued response and spatial memory. Relative to controls, the dyskinetic subjects showed a superior cued response performance but an equal spatial memory ability. We speculate that this selective facilitation may reflect dopaminergic hyperactivity in the dyskinetic group.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Collerton D,Fairbairn A,Britton Pdoi
10.1017/s0033291700023588subject
Has Abstractpub_date
1985-05-01 00:00:00pages
311-5issue
2eissn
0033-2917issn
1469-8978journal_volume
15pub_type
杂志文章abstract:BACKGROUND:Men sexually interested in children of a specific combination of maturity and sex tend to show some lesser interest in other categories of persons. Patterns of men's sexual interest across erotic targets' categories of maturity and sex have both clinical and basic scientific implications. METHOD:We examined...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720001476
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Attentional difficulties reported in individuals with anorexia nervosa (AN) may be due to preferential processing of disease-salient stimuli at a pre-attentive or at a conscious level or to a general problem in attention. Attentional difficulties may be associated with duration of illness. METHOD:Female par...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708002961
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Neurocognitive dysfunction in schizophrenia (SZ), bipolar (BD) and related disorders represents a core feature of these illnesses, possibly a marker of underlying pathophysiology. Substantial overlap in domains of neuropsychological deficits has been reported among these disorders after illness onset. Howeve...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291710001042
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The medial forebrain bundle (MFB) is an important pathway of the reward system. Two branches have been described using diffusion magnetic resonance imaging (MRI)-based tractography: the infero-medial MFB (imMFB) and the supero-lateral MFB (slMFB). Previous studies point to white-matter microstructural altera...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714001949
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Meta-analyses link childhood trauma to depression, mania, anxiety disorders, and psychosis. It is unclear, however, whether these outcomes truly represent distinct disorders following childhood trauma, or that childhood trauma is associated with admixtures of affective, psychotic, anxiety and manic psychopat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714002372
更新日期:2015-04-01 00:00:00
abstract::Seventy eight men were assessed one month before coronary artery bypass graft surgery using standardized measures of psychiatric morbidity and personality as well as a measure of emotional expression (the CECS). All patients had at least one coronary vessel occluded by 75% or more of its diameter, and functional capac...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700025939
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:Prevalence of childhood anxiety disorders at specific ages and genetic etiological influences on anxiety disorders in young children have been little studied. The present study reports prevalence estimates in a community sample of 6-year-old twins, and patterns of genetic and environmental influences on thes...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291705006537
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Empirical data regarding prevalence of sexual and physical abuse histories in Japanese patients with eating disorders is lacking, in contrast to Western countries. This study investigated the prevalence of traumatic events in Japanese patients with eating disorders, and examined the relationship between such...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799008557
更新日期:1999-07-01 00:00:00
abstract::The diversity of research methods applied to psychiatric disorders results in a confusing plethora of causal claims. To help make sense of these claims, the interventionist model (IM) of causality has several attractive features. First, it connects causation with the practical interests of psychiatry, defining causati...
journal_title:Psychological medicine
pub_type: 社论,评审
doi:10.1017/S0033291708004467
更新日期:2009-06-01 00:00:00
abstract::Biochemical studies of manic-depressive psychosis usually correlates biochemical findings with current affective state and hence any significant findings could be secondary to mood change. The present study attempts to correlate measures of the erythrocyte membrane cation carrier with clinical events, remote in time f...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291700013805
更新日期:1976-05-01 00:00:00
abstract:BACKGROUND:We report on the epidemiology of post-traumatic stress disorder (PTSD) in the Australian community, including information on lifetime exposure to trauma, 12-month prevalence of PTSD, sociodemographic correlates and co-morbidity. METHODS:Data were obtained from a stratified sample of 10,641 participants as p...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004287
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Post-traumatic symptomatology is one of the signature effects of the pernicious exposures endured by responders to the World Trade Center (WTC) disaster of 11 September 2001 (9/11), but the long-term extent of diagnosed Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) post-traumati...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715002184
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, but risk factors associated with cognitive deficits in euthymic BD are still poorly understood. We aimed to validate classification criteria for the identification of clinically significant cognitive...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718001186
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Structural models of emotional disorders propose that anxiety disorders can be classified into fear and distress disorders. Sources of evidence for this distinction come from genetic, self-report and neurophysiological data from adults. The present study examined whether this distinction relates to cognitive...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713000779
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The experience of childhood trauma is linked to more severe symptoms and poorer functioning in severe mental disorders; however, the mechanisms behind this are poorly understood. We investigate the relationship between childhood trauma and sleep disturbances in severe mental disorders including the role of s...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000914
更新日期:2020-04-23 00:00:00
abstract:BACKGROUND:Various childhood social experiences have been reported to predict adult outcomes. However, it is unclear how different social contexts may influence each other's effects in the long run. This study examined the joint contribution of adolescent family and peer experiences to young adult wellbeing and functio...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718001976
更新日期:2019-07-01 00:00:00
abstract::Depression is one of the most prevalent mental illnesses worldwide and a leading cause of disability, especially in the setting of treatment resistance. In recent years, repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising alternative strategy for treatment-resistant depression and its clinic...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291715001609
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Cannabis use is associated with altered neurocognitive functioning in severe mental disorders, but data are still inconclusive and there are no studies of bipolar disorder. The aim of this study was to investigate the association between cannabis use and neurocognition in bipolar disorder compared with schiz...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991620
更新日期:2010-08-01 00:00:00
abstract::Despite the robust body of work on cognitive aspects of bipolar disorder (BD), a clear profile of associated impairments in impulsivity, decision-making and risk-taking from studies that use behavioural measures has yet to be established. A systematic review, across four electronic databases (PsycINFO, MEDLINE/PubMed,...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003086
更新日期:2020-10-01 00:00:00
abstract::Using the 40-item Eating Attitudes Test and other self-report questions, a two-stage screening survey of 1020 (F 646, M 374) Chinese bilingual university students in Hong Kong showed that although female students were 'underweight' by Western standard, the majority of them and nearly all female students above a body m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028531
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Abnormalities in the anterior inter-hemispheric connectivity have previously been implicated in major depressive disorder. Disruptions in fractional anisotropy in the callosum and fornix have been reported in schizophrenia and major depressive disorder. Oligodendrocyte density and overall size of the callosu...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291715000136
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Depressive symptoms above screening thresholds have been shown to predict functional decline in older adults. Less is known about the impact of subthreshold depression, and whether more symptoms confer significantly greater risk compared to fewer symptoms. METHOD:Using data from the Duke Established Populat...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709005650
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Psychiatric disorders and related intermediate phenotypes are highly heritable and have a complex, overlapping polygenic architecture. A large-scale genome-wide association study (GWAS) of anxiety disorders identified genetic variants that are significant on a genome-wide. The current study investigated the ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171900059X
更新日期:2020-03-01 00:00:00
abstract::A number of computerized tests were used to study visual attention, memory and learning in elderly depressed patients. Impairment was found in approximately 70% of depressed patients and was seen particularly in memory and in measures of latency. Depressed patients showed equivalent impairment in short-term memory but...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700017025
更新日期:1990-08-01 00:00:00
abstract::In a 5-week study of 22 depressed patients treated with nortriptyline, significant changes in plasma levels, both elevated and reduced, were deliberately produced in the third and fourth weeks of each patient's treatment. Correlation of plasma nortriptyline levels and changes in the severity of depression, as measured...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700023163
更新日期:1977-02-01 00:00:00
abstract:BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder which frequently persists into adulthood. The primary goal of the current study was to (a) investigate attentional functions of stimulant medication-naïve adults with ADHD, and (b) investigate the effects of 6 weeks of methylphe...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718003628
更新日期:2019-11-01 00:00:00
abstract::In a study of domiciliary and out-patient treatment of self-poisoning patients, using a brief problem-orientated approach, it was found that domiciliary treatment resulted in much higher attendance rates but no difference in outcome. Patients who completed out-patient treatment had a better outcome than those who fail...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700053381
更新日期:1981-02-01 00:00:00
abstract:BACKGROUND:Discontinuation of antipsychotics predisposes patients with remitted/stable first-episode psychosis (FEP) to a higher risk of relapse, but it remains unclear how long discontinuation increases the relapse rate in these patients compared with maintenance. METHODS:This meta-analysis of randomized controlled t...
journal_title:Psychological medicine
pub_type: 杂志文章,meta分析
doi:10.1017/S0033291718001393
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The past two decades have seen a great improvement in the care of people with Prader-Willi syndrome (PWS), particularly with regard to control of diet and behaviour management. Has this affected mortality rates or thrown up new issues regarding premature ageing or dementia? We investigated two aspects of age...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291714001755
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Previous studies have provided initial evidence that people at risk for psychosis (PR) suffer from stigma and discrimination related to their condition. However, no study has systematically reviewed stigma and discrimination associated with being at PR and the potential underlying mechanisms. METHODS:This w...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720000148
更新日期:2020-04-01 00:00:00