The complex relationship between depressive symptoms and functional limitations in community-dwelling older adults: the impact of subthreshold depression.

abstract：BACKGROUND:This two-stage prevalence survey involved geographically delimited areas, four urban (Liverpool, Newcastle, Nottingham and Oxford) and two rural (Cambridgeshire and Gwynedd), including institutions. METHODS:Stratified random population samples of people in their 65th year and above, from Family Health Servi...

journal_title：Psychological medicine

authors：

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Although psychiatric patients with eating disorders are known to be at risk for a variety of health problems, relatively little is known about eating disorders and associated health problems in other populations. An epidemiological study was conducted to investigate health problems and impairment associated ...

journal_title：Psychological medicine

authors： Johnson JG,Spitzer RL,Williams JB

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Although family, twin and adoption studies have suggested that lifetime major depression (MD) is a heritable condition, nearly all these studies have relied for the diagnosis on long-term human memory, which is fallible and potentially biased. Could the estimates of heritability of MD be biased by the well-de...

journal_title：Psychological medicine

authors： Kendler KS,Aggen SH

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Depressive disorders are known to often be chronic and recurrent both in the general population and in psychiatric settings. However, despite its importance for public health and services, the outcome of depression in primary care is not well known. METHOD:In The Vantaa Primary Care Depression Study (PC-VDS...

journal_title：Psychological medicine

authors： Vuorilehto MS,Melartin TK,Isometsä ET

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:We studied whether heterogeneous profiles of cognitive function are relevant to survival in patients with early Alzheimer's disease. METHODS:CAMCOG subscales of cognitive function were used as predictors of survival, together with gender in 157 consecutively referred patients with early Alzheimer's disease....

journal_title：Psychological medicine

authors： Claus JJ,Walstra GJ,Bossuyt PM,Teunisse S,Van Gool WA

更新日期：1999-03-01 00:00:00

abstract：:Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...

journal_title：Psychological medicine

authors： Maier M,Ron MA,Barker GJ,Tofts PS

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:We examined the prevalence of self-perceived respiratory symptoms (SRS) in the absence of any objective findings of respiratory pathology, and the association of such prevalence with psychological factors and healthcare use in the general population. METHODS:The study was conducted among a nationally repres...

journal_title：Psychological medicine

authors： Selinheimo S,Vasankari T,Jokela M,Kanervisto M,Pirkola S,Suvisaari J,Paunio T

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Individual variation in the clinical course of bipolar disorder may have prognostic and therapeutic implications but is poorly reflected in current classifications. We aimed to establish a typology of the individual clinical trajectories based on detailed prospective medium-term follow-up. Method Latent clas...

journal_title：Psychological medicine

authors： Uher R,Mantere O,Suominen K,Isometsä E

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The attenuated positive symptoms syndrome (APSS) is considered an at-risk indicator for psychosis. However, the characteristics and developmental aspects of the combined or enriched risk criteria of APSS and basic symptom (BS) criteria, including self-experienced cognitive disturbances (COGDIS) remain under-...

journal_title：Psychological medicine

authors： Gerstenberg M,Theodoridou A,Traber-Walker N,Franscini M,Wotruba D,Metzler S,Müller M,Dvorsky D,Correll CU,Walitza S,Rössler W,Heekeren K

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiop...

journal_title：Psychological medicine

authors： Zammit S,Odd D,Horwood J,Thompson A,Thomas K,Menezes P,Gunnell D,Hollis C,Wolke D,Lewis G,Harrison G

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Evidence suggests some overlap between the pathological use of food and drugs, yet how impulsivity compares across these different clinical disorders remains unclear. Substance use disorders are commonly characterized by elevated impulsivity, and impulsivity subtypes may show commonalities and differences in...

journal_title：Psychological medicine

authors： Mole TB,Irvine MA,Worbe Y,Collins P,Mitchell SP,Bolton S,Harrison NA,Robbins TW,Voon V

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Adverse effects of antidepressants are most common at the beginning of the treatment, but possible also later. We examined the association between antidepressant use and work-related injuries taking into account the duration of antidepressant use. METHOD:Antidepressant use and work-related injuries between ...

journal_title：Psychological medicine

authors： Kouvonen A,Vahtera J,Pentti J,Korhonen MJ,Oksanen T,Salo P,Virtanen M,Kivimäki M

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:In a recent placebo-controlled, double-blind crossover trial (n = 52), significant beneficial effects on memory (d = 0.30) and negative symptoms (d = 0.29) were found after 12 weeks of memantine augmentation in patients with clozapine-refractory schizophrenia. In this open-label 1-year extension study we rep...

journal_title：Psychological medicine

authors： Veerman SR,Schulte PF,Deijen JB,de Haan L

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Previous work suggests that individuals with schizophrenia display an altered homovanillic acid (HVA) response to metabolic stress. The present study replicated and extended this paradigm, including individuals with elevated genetic risk for schizophrenia. METHOD:Patients with psychosis (n = 50), non-psycho...

journal_title：Psychological medicine

authors： Marcelis M,Cavalier E,Gielen J,Delespaul P,Van Os J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Early Intervention in Psychosis Services (EIS) for young people in England experiencing first-episode psychosis (FEP) were commissioned in 2002, based on an expected incidence of 15 cases per 100 000 person-years, as reported by schizophrenia epidemiology in highly urban settings. Unconfirmed reports from EI...

journal_title：Psychological medicine

authors： Cheng F,Kirkbride JB,Lennox BR,Perez J,Masson K,Lawrence K,Hill K,Feeley L,Painter M,Murray GK,Gallagher O,Bullmore ET,Jones PB

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:This study examined two competing hypotheses concerning the association between diabetes and treatment for depression: (1) the detection/ascertainment bias hypothesis suggesting that those with diabetes are more likely to be diagnosed with and treated for depression because of increased medical attention and...

journal_title：Psychological medicine

authors： Manderbacka K,Jokela M,Sund R,Elovainio M

更新日期：2014-04-01 00:00:00

abstract：:The psychiatric status of patients with chronic fatigue syndrome (N = 34) and muscle disease (N = 24) attending a general medical clinic was studied. Among fatigue patients 14 (41.2%) were cases and a further 9 (26.5%) were subcases of psychiatric disorder as defined by CATEGO. A variety of diagnoses was found. Signif...

journal_title：Psychological medicine

authors： Wood GC,Bentall RP,Göpfert M,Edwards RH

更新日期：1991-08-01 00:00:00

abstract：:Serum total androgens were estimated by radioimmunoassay on blood samples of treatment-seeking homosexuals and heterosexual controls. There was no significant difference in androgen levels between the homosexual and control group, nor was there any relationship between androgen levels and response to treatment. These ...

journal_title：Psychological medicine

authors： James S,Carter RA,Orwin A

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Structural models of emotional disorders propose that anxiety disorders can be classified into fear and distress disorders. Sources of evidence for this distinction come from genetic, self-report and neurophysiological data from adults. The present study examined whether this distinction relates to cognitive...

journal_title：Psychological medicine

authors： Waters AM,Bradley BP,Mogg K

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Existing evidence on profiles of psychological distress across adulthood uses cross-sectional or longitudinal studies with short observation periods. The objective of this research was to study the profile of psychological distress within the same individuals from early adulthood to early old age across thre...

journal_title：Psychological medicine

authors： Gondek D,Bann D,Patalay P,Goodman A,McElroy E,Richards M,Ploubidis GB

更新日期：2021-01-21 00:00:00

abstract：BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

journal_title：Psychological medicine

authors： Wheeldon TJ,Robertson C,Eagles JM,Reid IC

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Most evidence in the UK on the effectiveness of brief therapy for depression concerns cognitive behaviour therapy (CBT). In a trial published in 2000, we showed that non-directive counselling and CBT were equally effective in general practice for patients with depression and mixed anxiety and depression. Our...

journal_title：Psychological medicine

authors： King M,Marston L,Bower P

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), com...

journal_title：Psychological medicine

authors： Roberge P,Provencher MD,Gaboury I,Gosselin P,Vasiliadis HM,Benoît A,Carrier N,Antony MM,Chaillet N,Houle J,Hudon C,Norton PJ

更新日期：2020-12-02 00:00:00

abstract：:Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits such as memory and concentration problems tend to persist after mood symptoms recover. Improving c...

journal_title：Psychological medicine

authors： Kaser M,Zaman R,Sahakian BJ

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Prior optical coherence tomography (OCT) studies of schizophrenia have identified thinning of retinal layers. However, findings have varied across reports, and most studies have had serious methodological limitations. To address unresolved issues, we determined whether: (1) retinal thinning in schizophrenia ...

journal_title：Psychological medicine

authors： Silverstein SM,Paterno D,Cherneski L,Green S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Cognitive theory points to the importance of negative self-schemas in the onset and maintenance of depression and anxiety disorders. Hereby, it is important to distinguish between automatic and explicit self-schemas, reflecting different cognitive-motivational systems. This study tested whether patients with...

journal_title：Psychological medicine

authors： Glashouwer KA,de Jong PJ

更新日期：2010-07-01 00:00:00

abstract：:An attempt was made to identify background, sociodemographic and clinical variables which are associated with attempted suicide in depression. Within a sample of 308 depressed psychiatric inpatients, suicide attempters were younger than non-attempters and were identified by a pattern of chronic interpersonal maladjust...

journal_title：Psychological medicine

authors： Crook T,Raskin A,Davis D

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Previous studies have highlighted the role of the brain reward and cognitive control systems in the etiology of anorexia nervosa (AN). In an attempt to disentangle the relative contribution of these systems to the disorder, we used functional magnetic resonance imaging (fMRI) to investigate hemodynamic respo...

journal_title：Psychological medicine

authors： Boehm I,King JA,Bernardoni F,Geisler D,Seidel M,Ritschel F,Goschke T,Haynes JD,Roessner V,Ehrlich S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Both past depressive episodes and the personality trait of depressive rumination are strong risk factors for future depression. Depression is associated with abnormal emotional processing, which may be a neurobiological marker for vulnerability to depression. A consistent picture has yet to emerge as to how ...

journal_title：Psychological medicine

authors： Thomas EJ,Elliott R,McKie S,Arnone D,Downey D,Juhasz G,Deakin JF,Anderson IM

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that offspring of mothers with psychotic disorders have an almost two-fold higher mortality risk from birth until early adulthood. We investigated predictors of mortality from late adolescence until middle age in offspring of mothers with psychotic disorders. METHOD:The Helsinki Hig...

journal_title：Psychological medicine

authors： Suvisaari J,Häkkinen L,Haukka J,Lönnqvist J

更新日期：2008-08-01 00:00:00