Abnormal response to metabolic stress in schizophrenia: marker of vulnerability or acquired sensitization?

abstract：:There have been numerous exhortations for more 'translational research'. A selective review of historical examples of research leading to health benefits is used to consider the various forms of successful interplay between basic science and clinical applications. This is followed by a consideration of key neuroscienc...

journal_title：Psychological medicine

authors： Rutter M,Plomin R

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Individual variation in the clinical course of bipolar disorder may have prognostic and therapeutic implications but is poorly reflected in current classifications. We aimed to establish a typology of the individual clinical trajectories based on detailed prospective medium-term follow-up. Method Latent clas...

journal_title：Psychological medicine

authors： Uher R,Mantere O,Suominen K,Isometsä E

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Discriminating Alzheimer's disease (AD) and mild cognitive impairment (MCI) from depression is a challenge in psychogeriatric medicine. A study was set up to ascertain whether cued recall could be useful in differentiating early AD and MCI from depression among elderly individuals. METHOD:The Visual Associa...

journal_title：Psychological medicine

authors： Dierckx E,Engelborghs S,De Raedt R,De Deyn PP,Ponjaert-Kristoffersen I

更新日期：2007-05-01 00:00:00

abstract：:A review of research on kleptomania--the syndrome of compulsive stealing--suggests that kleptomania may be a common disorder, especially among women, and that it may frequently be associated with other forms of psychopathology, such as mood, anxiety, and eating disorders. There appears to be a range of abnormal or non...

journal_title：Psychological medicine

authors： McElroy SL,Hudson JI,Pope HG,Keck PE

更新日期：1991-02-01 00:00:00

abstract：:The value of services for those with the 'At Risk Mental State for Psychosis' (ARMS) continues to be disputed. ARMS services have provided a valuable stimulus to academic research into the transition into psychosis. Furthermore, there is currently a welcome trend to transform such clinics into youth mental health serv...

journal_title：Psychological medicine

authors： Murray RM,David AS,Ajnakina O

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for ...

journal_title：Psychological medicine

authors： Madsen IEH,Nyberg ST,Magnusson Hanson LL,Ferrie JE,Ahola K,Alfredsson L,Batty GD,Bjorner JB,Borritz M,Burr H,Chastang JF,de Graaf R,Dragano N,Hamer M,Jokela M,Knutsson A,Koskenvuo M,Koskinen A,Leineweber C,Niedhamme

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Previous research in resting-state functional magnetic resonance imaging (rs-fMRI) has shown a mixed pattern of disrupted thalamocortical connectivity in psychosis. The clinical meaning of these findings and their stability over time remains unclear. We aimed to study thalamocortical connectivity longitudina...

journal_title：Psychological medicine

authors： Bergé D,Lesh TA,Smucny J,Carter CS

更新日期：2020-12-16 00:00:00

abstract：:Potential cases of presenile dementia of the Alzheimer type (PDAT) in the Northern Health Region (estimated population aged 45-64, 655,800) were ascertained for the years 1979-86 from in-patient ICD-9 codes and other sources. An algorithm was applied to the casenote information to distinguish between Alzheimer-type an...

journal_title：Psychological medicine

authors： Newens AJ,Forster DP,Kay DW,Kirkup W,Bates D,Edwardson J

更新日期：1993-08-01 00:00:00

abstract：:Previous studies have reported an increase in depression among recent birth cohorts. Concurrent with the increase in rates of depression, there have been increases in rates of drug and alcohol abuse and dependence. This study sought to determine if the recent increase in rates of depression could be attributed to co-m...

journal_title：Psychological medicine

authors： Klerman GL,Leon AC,Wickramaratne P,Warshaw MG,Mueller TI,Weissman MM,Akiskal H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Neurocognitive functioning may be impaired in the luteal phase of the menstrual cycle due to associated changes in hypothalamic-pituitary adrenal (HPA) axis function. This study examines the relationship between changes in neurocognition and HPA axis function in different phases of the menstrual cycle. METH...

journal_title：Psychological medicine

authors： Symonds CS,Gallagher P,Thompson JM,Young AH

更新日期：2004-01-01 00:00:00

abstract：:General practitioners using DSM-III criteria have studied the incidence and prevalence of anorexia nervosa and bulimia nervosa in a large (N = 151,781) representative sample of the Dutch population. The incidence rate for anorexia nervosa is 6.3 and for bulimia nervosa 9.9 per year per 100,000 population. The prevalen...

journal_title：Psychological medicine

authors： Hoek HW

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Classification of psychosis lacks a biological basis and current diagnostic categories may obscure underlying continuities. Data reduction methods of symptom profiles within a population-based cohort of people with a wide range of affective and non-affective psychoses may permit an empirical classification o...

journal_title：Psychological medicine

authors： Murray V,McKee I,Miller PM,Young D,Muir WJ,Pelosi AJ,Blackwood DH

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Assortative mating has been demonstrated in mental disorders but the extent of cohabitation between patients with clinically diagnosed psychiatric disease has been poorly explored. Method We conducted a register-based study of all Danes between 18 and 70 years of age in a 13-year observational period, linkin...

journal_title：Psychological medicine

authors： Thomsen AF,Olsbjerg M,Andersen PK,Kessing LV

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:We examined the relationship between childhood sexual abuse (CSA), and interviewees' recollections of pathogenic parenting, testing for possible retrospective biases in the recollections of those who have experienced CSA. METHODS:Information about CSA, parental divorce and interviewees' recollections of par...

journal_title：Psychological medicine

authors： McLaughlin TL,Heath AC,Bucholz KK,Madden PA,Bierut LJ,Slutske WS,Dinwiddie S,Statham DJ,Dunne MP,Martin NG

更新日期：2000-11-01 00:00:00

abstract：:The concept of allusive thinking is briefly reviewed and a Pavlovian model of thinking advanced. It is hypothesized that allusive, as compared with non-allusive thinkers, have a broader but less intense attention process associated with weaker inhibition. From this model it was predicted that on word tests which requi...

journal_title：Psychological medicine

authors： Armstrong MS,McConaghy N

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Bright light and high-density negative air ion exposure are efficacious for winter and non-seasonal depression compared with a low-density negative ion placebo. Similarly, auditory stimuli improve mood in clinical populations. This study compared the short-term effects of bright light, an auditory stimulus, ...

journal_title：Psychological medicine

authors： Goel N,Etwaroo GR

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Attention-deficit hyperactivity disorder (ADHD) is associated with poorer cognitive functioning. We used a developmental, genetically-sensitive approach to examine intelligence quotient (IQ) from early childhood to young adulthood among those with different ADHD courses to investigate whether changes in ADHD...

journal_title：Psychological medicine

authors： Agnew-Blais JC,Polanczyk GV,Danese A,Wertz J,Moffitt TE,Arseneault L

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Whether late-onset depression is a risk factor for or a prodrome of dementia remains unclear. We investigated the impact of depressive symptoms and early- v. late-onset depression on subsequent dementia in a cohort of elderly general-practitioner patients (n = 2663, mean age = 81.2 years). METHOD:Risk for s...

journal_title：Psychological medicine

authors： Heser K,Tebarth F,Wiese B,Eisele M,Bickel H,Köhler M,Mösch E,Weyerer S,Werle J,König HH,Leicht H,Pentzek M,Fuchs A,Riedel-Heller SG,Luppa M,Prokein J,Scherer M,Maier W,Wagner M,Age CoDe Study Group.

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Although many studies have addressed the topic of stability versus change in depressive symptoms, few have further decomposed the change to continuous accumulation versus non-systematic state fluctuations or measurement errors. This further step requires a longitudinal follow-up and an appropriate stochastic...

journal_title：Psychological medicine

authors： Rosenström T,Jokela M,Hintsanen M,Pulkki-Råback L,Hutri-Kähönen N,Keltikangas-Järvinen L

更新日期：2013-05-01 00:00:00

abstract：:Results are reported from a large population study (of working people) comparing Holocaust survivors and a control group in regard to emotional distress, satisfaction in life and psychosomatic symptoms. It was found that, even 40 years after the traumatic experience, this group of survivors exhibited a slightly higher...

journal_title：Psychological medicine

authors： Carmil D,Carel RS

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD), such that MDD has been associated with guilt-driven pathological hyper-altruism. However, the impact of such emotional impairments in MDD on different ...

journal_title：Psychological medicine

authors： Pulcu E,Thomas EJ,Trotter PD,McFarquhar M,Juhasz G,Sahakian BJ,Deakin JF,Anderson IM,Zahn R,Elliott R

更新日期：2015-04-01 00:00:00

abstract：:The term 'pseudohallucination' is currently used to name imaginal experiences whose relationship to one another and to hallucinations 'proper' remains obscure. Clinicians, including specialists in psychopathology, disagree on how pseudohallucination must be defined and on its diagnostic role. Empirical research is unl...

journal_title：Psychological medicine

authors： Berrios GE,Dening TR

更新日期：1996-07-01 00:00:00

abstract：:Social anxiety disorder is one of the most common comorbid conditions in eating disorders (EDs). The aim of the current review and meta-analysis is to provide a qualitative summary of what is known about social anxiety (SA) in EDs, as well as to compare levels of SA in those with EDs and healthy controls. Electronic d...

journal_title：Psychological medicine

authors： Kerr-Gaffney J,Harrison A,Tchanturia K

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Although alcohol use disorder (AUD) is associated with future risk for psychosocial dysfunction, the degree to which this arises from a direct causal effect of AUD on functioning v. from correlated risk factors (also known as confounders) is less clearly established. METHOD:AUD was assessed from Swedish med...

journal_title：Psychological medicine

authors： Kendler KS,Ohlsson H,Karriker-Jaffe KJ,Sundquist J,Sundquist K

更新日期：2017-04-01 00:00:00

abstract：:It is generally recognized that social relationships occupy a central position in psychiatry. To examine the role of social relationships in the onset of minor psychiatric morbidity it is necessary to construct an instrument which will meet the need for a valid, reliable and comprehensive index of social relationships...

journal_title：Psychological medicine

authors： Henderson S,Duncan-Jones P,Byrne DG,Scott R

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:The assessment of inter-regional functional connectivity (FC) has allowed for the description of the putative mechanism of action of treatments such as deep brain stimulation (DBS) of the nucleus accumbens in patients with obsessive-compulsive disorder (OCD). Nevertheless, the possible FC alterations of othe...

journal_title：Psychological medicine

authors： Cano M,Alonso P,Martínez-Zalacaín I,Subirà M,Real E,Segalàs C,Pujol J,Cardoner N,Menchón JM,Soriano-Mas C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Mental stress is associated with higher mortality, but it remains controversial whether the association is causal or a consequence of a higher physical disease burden in those with a high mental stress load. Understanding causality is important when developing targeted interventions. We aimed to estimate the...

journal_title：Psychological medicine

authors： Prior A,Fenger-Grøn M,Davydow DS,Olsen J,Li J,Guldin MB,Vestergaard M

更新日期：2018-07-01 00:00:00

abstract：:Eighty-three chronic obstructive bronchitic patients were psychologically assessed before being randomly allocated to 1 of 3 management regimes. The following measures were taken: psychiatric disturbance, personality, social-desirability response set, vocabulary, expectations about treatment, attitudes and beliefs abo...

journal_title：Psychological medicine

authors： Rutter BM

更新日期：1979-02-01 00:00:00

abstract：:Five hundred and eighty schoolgirls living in a small North Indian industrial town were screened using the EAT-26. Although twenty-nine per cent scored above the threshold for the questionnaire (greater than or equal to 20), closer scrutiny of the pattern of responses revealed misinterpretations of a large number of q...

journal_title：Psychological medicine

authors： King MB,Bhugra D

更新日期：1989-11-01 00:00:00

abstract：:Comparison between general practice attenders and community subjects with emotional distress (as measured by GHQ-12) showed that women from a general practice sample reported more social problems than those from the community. In both men and women, problems with their spouse or partner were far more likely among gene...

journal_title：Psychological medicine

authors： Pini S,Piccinelli M,Zimmermann-Tansella C

更新日期：1995-01-01 00:00:00