The role of drug and alcohol abuse in recent increases in depression in the US.

abstract：BACKGROUND:Clinical intuition suggests that personality disorders hinder the treatment of depression, but research findings are mixed. One reason for this might be the way in which current assessment measures conflate general aspects of personality disorders, such as overall severity, with specific aspects, such as sty...

journal_title：Psychological medicine

authors： Constantinou MP,Frueh BC,Fowler JC,Allen JG,Madan A,Oldham JM,Fonagy P

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Aberrant emotional biases have been reported in bipolar disorder (BD), but results are inconsistent. Despite the clinical relevance of chronic mood variability in BD, there is no previous research investigating how the extent of symptom fluctuations in bipolar disorder might relate to emotional biases. This ...

journal_title：Psychological medicine

authors： Bilderbeck AC,Reed ZE,McMahon HC,Atkinson LZ,Price J,Geddes JR,Goodwin GM,Harmer CJ

更新日期：2016-11-01 00:00:00

abstract：:Twenty schizophrenic patients with tardive dyskinesia and an equal number of matched controls were tested on a novel cognitive task. The task had two components: cued response and spatial memory. Relative to controls, the dyskinetic subjects showed a superior cued response performance but an equal spatial memory abili...

journal_title：Psychological medicine

authors： Collerton D,Fairbairn A,Britton P

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups ar...

journal_title：Psychological medicine

authors： Fearon P,Kirkbride JB,Morgan C,Dazzan P,Morgan K,Lloyd T,Hutchinson G,Tarrant J,Fung WL,Holloway J,Mallett R,Harrison G,Leff J,Jones PB,Murray RM,AESOP Study Group.

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Pharmaceutical industry funding of psychiatric research has increased significantly in recent decades, raising the question of a relationship between pharmaceutical company funding of clinical psychiatric studies and the outcomes of those studies. This study examines this relationship. METHOD:Abstracts of a...

journal_title：Psychological medicine

authors： Kelly RE Jr,Cohen LJ,Semple RJ,Bialer P,Lau A,Bodenheimer A,Neustadter E,Barenboim A,Galynker II

更新日期：2006-11-01 00:00:00

abstract：:Consciousness has evolved and is a feature of all animals with sufficiently complex nervous systems. It is, therefore, primarily a problem for biology, rather than physics. In this review, I will consider three aspects of consciousness: level of consciousness, whether we are awake or in a coma; the contents of conscio...

journal_title：Psychological medicine

authors： Frith CD

更新日期：2019-09-04 00:00:00

abstract：:A community survey of psychiatric disorder carried out in South London enabled the authors to investigate the 'vulnerability model' proposed by Brown & Harris (1978). In the current study none of the 'vulnerability factors' proposed by Brown & Harris fulfilled the requirements of the model. It was, however, found that...

journal_title：Psychological medicine

authors： Bebbington PE,Sturt E,Tennant C,Hurry J

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:The atypical processing of eye contact is a characteristic hallmark of autism spectrum disorder (ASD). The severity of these symptoms, however, is thought to lie on a continuum that extends into the typical population. While behavioural evidence shows that differences in social cognitive tasks in typically d...

journal_title：Psychological medicine

authors： Madipakkam AR,Rothkirch M,Dziobek I,Sterzer P

更新日期：2019-04-01 00:00:00

abstract：:The Committee on Chronotherapeutics, delegated by the International Society for Affective Disorders (ISAD), makes the following recommendations after reviewing the evidence as of November 2004. (1) Wake therapy is the most rapid antidepressant available today: approximately 60% of patients, independent of diagnostic s...

journal_title：Psychological medicine

authors： Wirz-Justice A,Benedetti F,Berger M,Lam RW,Martiny K,Terman M,Wu JC

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Twenty states currently require that women seeking abortion be counseled on possible psychological responses, with six states stressing negative responses. The majority of research finds that women whose unwanted pregnancies end in abortion do not subsequently have adverse mental health outcomes; scant resea...

journal_title：Psychological medicine

authors： Gomez AM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Attentional difficulties reported in individuals with anorexia nervosa (AN) may be due to preferential processing of disease-salient stimuli at a pre-attentive or at a conscious level or to a general problem in attention. Attentional difficulties may be associated with duration of illness. METHOD:Female par...

journal_title：Psychological medicine

authors： Dickson H,Brooks S,Uher R,Tchanturia K,Treasure J,Campbell IC

更新日期：2008-12-01 00:00:00

abstract：:Ten depressed patients were assessed on an auditory signal detection task; testing was repeated on remission. The patients' clinical state was monitored by means of the Hamilton rating scale and the Beck Depression Inventory. The task was performed under three conditions: 2 button (Yes/No); 1 button (Yes); 1 button (N...

journal_title：Psychological medicine

authors： Malone JR,Hemsley DR

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined. METHOD:A total of 167 consecutive patients admitted to the stroke units of two university hospitals after an ischaemic stroke and 109 controls received extensive m...

journal_title：Psychological medicine

authors： Brodaty H,Sachdev PS,Withall A,Altendorf A,Valenzuela MJ,Lorentz L

更新日期：2005-12-01 00:00:00

abstract：:Monthly hospital admission rates (HA) for mania were classified by sex, type of admission (first, or re-admission) and by country (England and Wales or Scotland). Of the 8 classes thus created, all but one showed a statistically significant annual cycle with a peak in Summer and trough in Winter. There was no signific...

journal_title：Psychological medicine

authors： Myers DH,Davies P

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Patients treated in primary care settings report better mental outcomes when they agree with practitioners about the nature of their core presenting problems. However, no study has examined the impact of staff-patient agreement on treatment outcomes in specialist mental health services. We investigated wheth...

journal_title：Psychological medicine

authors： Lasalvia A,Bonetto C,Tansella M,Stefani B,Ruggeri M

更新日期：2008-01-01 00:00:00

abstract：:Messenger RNA (mRNA) is the key intermediate in the gene expression pathway. The amount of mRNA in Alzheimer's disease (AD) brains has been determined using in situ hybridization histochemistry (ISHH) to detect the poly(A) tails of polyadenylated mRNA (poly(A) + mRNA). On a regional basis, AD cases had significantly l...

journal_title：Psychological medicine

authors： Harrison PJ,Barton AJ,Najlerahim A,McDonald B,Pearson RC

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiop...

journal_title：Psychological medicine

authors： Zammit S,Odd D,Horwood J,Thompson A,Thomas K,Menezes P,Gunnell D,Hollis C,Wolke D,Lewis G,Harrison G

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The National Psychiatric Morbidity Survey (NPMS) programme was partly designed to monitor trends in mental disorders, including depression, with comparable data spanning 1993 to 2007. Findings already published from this programme suggest that concerns about increasing prevalence of common mental disorders (...

journal_title：Psychological medicine

authors： Spiers N,Brugha TS,Bebbington P,McManus S,Jenkins R,Meltzer H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...

journal_title：Psychological medicine

authors： Pritchard C,Amanullah S

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Preclinical and human studies suggest an association between chronic inflammation and the development of depressive behaviors. This is proposed to occur through downstream effects of inflammatory cytokines on neuroplasticity, neurogenesis and neurotransmitter function, although the neural correlates remain p...

journal_title：Psychological medicine

authors： Ironside M,Admon R,Maddox SA,Mehta M,Douglas S,Olson DP,Pizzagalli DA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Psychiatric history, familial history of suicide attempts, and certain traumatic life events are important predictors of suicidal thoughts and behaviour. We examined the epidemiology and genetics of suicidality (i.e. reporting persistent suicidal thoughts or a plan or suicide attempt) in a large community-ba...

journal_title：Psychological medicine

authors： Statham DJ,Heath AC,Madden PA,Bucholz KK,Bierut L,Dinwiddie SH,Slutske WS,Dunne MP,Martin NG

更新日期：1998-07-01 00:00:00

abstract：:Changes in the erythrocyte membrane cation carrier following lithium ingestion in normal human subjects were studied; ouabain sensitive potassium influx fell significantly during the lithium treated phase. Lithium was fed to rats and no change in erythrocyte Na-K ATPase was shown. These findings contrast with studies ...

journal_title：Psychological medicine

authors： Naylor GJ,Smith A,Boardman LJ,Dick DA,Dick EG,Dick P

更新日期：1977-05-01 00:00:00

abstract：:Serum total androgens were estimated by radioimmunoassay on blood samples of treatment-seeking homosexuals and heterosexual controls. There was no significant difference in androgen levels between the homosexual and control group, nor was there any relationship between androgen levels and response to treatment. These ...

journal_title：Psychological medicine

authors： James S,Carter RA,Orwin A

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Controlled prospective studies of the simultaneous long-term outcome of several mental disorders are rare. This study sought to determine if there were important differences between the outcome of anxiety and depressive disorders after 12 years and to examine their main predictors. METHOD:A cohort of 210 pe...

journal_title：Psychological medicine

authors： Tyrer P,Seivewright H,Johnson T

更新日期：2004-11-01 00:00:00

abstract：:The SIDAM--a new instrument for the symptomatic diagnosis and measurement of dementia according to DSM-III-R and ICD-10--is described. It comprises a brief structured clinical interview, a range of cognitive tests (e.g. including the Mini-Mental State (Folstein et al. 1975)) which constitute a short neuropsychological...

journal_title：Psychological medicine

authors： Zaudig M,Mittelhammer J,Hiller W,Pauls A,Thora C,Morinigo A,Mombour W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:There is not yet consensus on the best diagnostic definition of mixed bipolar episodes. Many have suggested the DSM-III-R/-IV definition is too rigid. We propose alternative criteria using data from a large patient cohort. METHODS:We evaluated 237 manic in-patients using DSM-III-R criteria and the Scale for...

journal_title：Psychological medicine

authors： Cassidy F,Ahearn E,Murry E,Forest K,Carroll BJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Executive impairments have been reported in affective illness, but the influence of attention on executive performance has not been fully considered. The purpose of this study was to investigate whether executive impairments in affective illness were independent of attention impairments, and whether independ...

journal_title：Psychological medicine

authors： Stoddart SD,Craddock NJ,Jones LA

更新日期：2007-11-01 00:00:00

abstract：:In the face of shifting demographics and an increase in human longevity, it is important to examine carefully what is known about cognitive ageing, and to identify and promote possibly malleable lifestyle and health-related factors that might mitigate age-associated cognitive decline. The Lothian Birth Cohorts of 1921...

journal_title：Psychological medicine

authors： Corley J,Cox SR,Deary IJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The correlates of insight in early-onset psychosis have received little previous attention. METHOD:We studied clinical correlates of insight in a sample of 110 adolescent recent-onset psychosis patients (mean age 15.53 years; psychotic symptoms present for <6 months). Insight was measured with the Scale to ...

journal_title：Psychological medicine

authors： Parellada M,Fraguas D,Bombín I,Otero S,Castro-Fornieles J,Baeza I,Gonzalez-Pinto A,Graell M,Soutullo C,Paya B,Arango C

更新日期：2009-09-01 00:00:00

abstract：:One hundred and nine adults were screened in the community using the abridged version of the CIDI (CIDIS). The subjects comprised DSM-III-R current cases (N = 48), lifetime cases (N = 31) and non-cases (N = 30). The interviews with the 109 subjects were conducted by one of two pairs of clinicians and videotaped. Each ...

journal_title：Psychological medicine

authors： Lesage AD,Fournier L,Cyr M,Toupin J,Fabian J,Gaudette G,Vanier C,Bebbington PE,Brewin CR

更新日期：1996-03-01 00:00:00