Impulsivity in disorders of food and drug misuse.

Abstract:

BACKGROUND:Evidence suggests some overlap between the pathological use of food and drugs, yet how impulsivity compares across these different clinical disorders remains unclear. Substance use disorders are commonly characterized by elevated impulsivity, and impulsivity subtypes may show commonalities and differences in various conditions. We hypothesized that obese subjects with binge-eating disorder (BED) and abstinent alcohol-dependent cohorts would have relatively more impulsive profiles compared to obese subjects without BED. We also predicted decision impulsivity impairment in obesity with and without BED. METHOD:Thirty obese subjects with BED, 30 without BED and 30 abstinent alcohol-dependent subjects and age- and gender-matched controls were tested on delay discounting (preference for a smaller immediate reward over a larger delayed reward), reflection impulsivity (rapid decision making prior to evidence accumulation) and motor response inhibition (action cancellation of a prepotent response). RESULTS:All three groups had greater delay discounting relative to healthy volunteers. Both obese subjects without BED and alcohol-dependent subjects had impaired motor response inhibition. Only obese subjects without BED had impaired integration of available information to optimize outcomes over later trials with a cost condition. CONCLUSIONS:Delay discounting appears to be a common core impairment across disorders of food and drug intake. Unexpectedly, obese subjects without BED showed greater impulsivity than obese subjects with BED. We highlight the dissociability and heterogeneity of impulsivity subtypes and add to the understanding of neurocognitive profiles across disorders involving food and drugs. Our results have therapeutic implications suggesting that disorder-specific patterns of impulsivity could be targeted.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Mole TB,Irvine MA,Worbe Y,Collins P,Mitchell SP,Bolton S,Harrison NA,Robbins TW,Voon V

doi

10.1017/S0033291714001834

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

771-82

issue

4

eissn

0033-2917

issn

1469-8978

pii

S0033291714001834

journal_volume

45

pub_type

杂志文章
  • Desperate remedies: a Gothic tale of madness and modern medicine.

    abstract::The theory that many diseases were produced by focal infection or chronic sepsis enjoyed a brief vogue in general medicine in the first quarter of the twentieth century. This paper explores its practical applications in psychiatry, which extended well into the 1930s. The analysis focuses particularly closely on the ac...

    journal_title:Psychological medicine

    pub_type: 历史文章,杂志文章,评审

    doi:10.1017/s0033291700025824

    authors: Scull A

    更新日期:1987-08-01 00:00:00

  • Environmental risk factors for Alzheimer's disease: their relationship to age of onset and to familial or sporadic types.

    abstract::Data from a case-control study of Alzheimer's disease (AD) were analysed in relation to age of onset and familial/sporadic status. The analyses were restricted to environmental exposures which might injure the brain. Later-onset AD was found to be positively associated with starvation/malnutrition and with nose-pickin...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700030373

    authors: Henderson AS,Jorm AF,Korten AE,Creasey H,McCusker E,Broe GA,Longley W,Anthony JC

    更新日期:1992-05-01 00:00:00

  • Clinical psychiatric illness in prisoners of war of the Japanese: forty years after release.

    abstract::Clinical psychiatric and medical assessments were carried out on a randomly selected sample of Australian prisoners of war captured by the Japanese in 1942 and a sample of combatants from Pacific theatres of war who were not captured. Prisoners of war had significantly more anxiety and depressive 'neuroses' and more m...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700011843

    authors: Tennant C,Goulston K,Dent O

    更新日期:1986-11-01 00:00:00

  • Treating severe and enduring anorexia nervosa: a randomized controlled trial.

    abstract:BACKGROUND:There are no evidence-based treatments for severe and enduring anorexia nervosa (SE-AN). This study evaluated the relative efficacy of cognitive behavioral therapy (CBT-AN) and specialist supportive clinical management (SSCM) for adults with SE-AN. METHOD:Sixty-three participants with a diagnosis of AN, who...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1017/S0033291713000949

    authors: Touyz S,Le Grange D,Lacey H,Hay P,Smith R,Maguire S,Bamford B,Pike KM,Crosby RD

    更新日期:2013-12-01 00:00:00

  • The extent of mental and physical ill-health of clients referred to social workers in a local authority department and a general attachment scheme.

    abstract::Information regarding the physical and mental health of clients referred to social workers in a local authority intake team and to a general practice attachment scheme was collected over a 3-month period. Although returns to the Department of Health and Social Security during this period indicated that a very low prop...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700032153

    authors: Corney RH

    更新日期:1979-08-01 00:00:00

  • Spontaneous movement disorders in antipsychotic-naive patients with first-episode psychoses: a systematic review.

    abstract:BACKGROUND:Spontaneous movement disorders (SMDs), such as spontaneous dyskinesia and parkinsonism, have been described in patients with schizophrenia who have never been treated with antipsychotic medication. Their presence has been documented extensively in chronic schizophrenia but not at the time of illness onset. ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291708004716

    authors: Pappa S,Dazzan P

    更新日期:2009-07-01 00:00:00

  • White-matter markers for psychosis in a prospective ultra-high-risk cohort.

    abstract:BACKGROUND:Subjects at 'ultra high risk' (UHR) for developing psychosis have differences in white matter (WM) compared with healthy controls. WM integrity has not yet been investigated in UHR subjects in relation to the development of subsequent psychosis. Hence, we investigated a prospective cohort of UHR subjects com...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709991711

    authors: Bloemen OJ,de Koning MB,Schmitz N,Nieman DH,Becker HE,de Haan L,Dingemans P,Linszen DH,van Amelsvoort TA

    更新日期:2010-08-01 00:00:00

  • Psychiatric morbidity in patients with Parkinson's disease.

    abstract::Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, rev...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700013246

    authors: Brown RG,MacCarthy B

    更新日期:1990-02-01 00:00:00

  • The effects of cognitive and behavioural therapies for anxiety disorders on depression: a meta-analysis.

    abstract:BACKGROUND:The effects of cognitive behavioural therapy of anxiety disorders on depression has been examined in previous meta-analyses, suggesting that these treatments have considerable effects on depression. In the current meta-analysis we examined whether the effects of treatments of anxiety disorders on depression ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,meta分析

    doi:10.1017/S0033291716002348

    authors: Cuijpers P,Cristea IA,Weitz E,Gentili C,Berking M

    更新日期:2016-12-01 00:00:00

  • Decision-making cognition in mania and depression.

    abstract:BACKGROUND:Despite markedly different clinical presentations, few studies have reported differences in neuropsychological functioning between mania and depression. Recent work has suggested that differences may emerge on cognitive tasks requiring affective processing, such as decision-making. The present study sought t...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291701003804

    authors: Murphy FC,Rubinsztein JS,Michael A,Rogers RD,Robbins TW,Paykel ES,Sahakian BJ

    更新日期:2001-05-01 00:00:00

  • Incremental benefits and cost of coordinated anxiety learning and management for anxiety treatment in primary care.

    abstract:BACKGROUND:Improving the quality of mental health care requires integrating successful research interventions into 'real-world' practice settings. Coordinated Anxiety Learning and Management (CALM) is a treatment-delivery model for anxiety disorders encountered in primary care. CALM offers cognitive behavioral therapy ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1017/S0033291711002893

    authors: Joesch JM,Sherbourne CD,Sullivan G,Stein MB,Craske MG,Roy-Byrne P

    更新日期:2012-09-01 00:00:00

  • Depression, smoking, and lung cancer risk over 24 years among women.

    abstract:BACKGROUND:Studies evaluating depression's role in lung cancer risk revealed contradictory findings, partly because of the small number of cases, short follow-up periods, and failure to account for key covariates including smoking exposure. We investigated the association of depressive symptoms with lung cancer risk in...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720004390

    authors: Trudel-Fitzgerald C,Zevon ES,Kawachi I,Tucker-Seeley RD,Kubzansky LD

    更新日期:2020-12-03 00:00:00

  • Stalkers and harassers of royalty: the role of mental illness and motivation.

    abstract:BACKGROUND:Public figures are at increased risk of attracting unwanted attention in the form of intrusions, stalking and, occasionally, attack. Whereas the potential threat to the British Royal Family from terrorists and organized groups is clearly defined, there is a dearth of knowledge about that from individual hara...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709005443

    authors: James DV,Mullen PE,Pathé MT,Meloy JR,Preston LF,Darnley B,Farnham FR

    更新日期:2009-09-01 00:00:00

  • Bulimia nervosa: a four- to six-year follow-up study.

    abstract::A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700005766

    authors: Hsu LK,Sobkiewicz TA

    更新日期:1989-11-01 00:00:00

  • Psychotic reactions to daily life stress and dopamine function in people with severe hearing impairment.

    abstract:BACKGROUND:Minor stresses measured in daily life have repeatedly been associated with increased momentary psychotic experiences, both in individuals with psychotic disorders and in persons who are genetically at an increased risk for these disorders. Severe hearing impairment (SHI) is an environmental risk factor for p...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714002797

    authors: Gevonden MJ,Myin-Germeys I,van den Brink W,van Os J,Selten JP,Booij J

    更新日期:2015-06-01 00:00:00

  • Panic attacks and the risk of personality disorder.

    abstract:OBJECTIVE:The goal of this study is to determine the association between panic attacks in adolescence and the risk of personality disorders during young adulthood. METHOD:Data were drawn from the Children in the Community Study, a longitudinal epidemiological study of psychopathology across the life-course in 717 indi...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704003319

    authors: Goodwin RD,Brook JS,Cohen P

    更新日期:2005-02-01 00:00:00

  • Psychological and physical morbidity in the aftermath of a cyclone.

    abstract::A Fijian community affected by a cyclone was compared with an unaffected but similar community. Two months after the cyclone both psychological and physical morbidity was 2-3 times greater in the affected community than in controls. By the third month morbidity had resolved to levels similar to those in the unaffected...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700010412

    authors: Fairley M,Langeluddecke P,Tennant C

    更新日期:1986-08-01 00:00:00

  • Effects of early life stress on depression, cognitive performance and brain morphology.

    abstract:BACKGROUND:Childhood early life stress (ELS) increases risk of adulthood major depressive disorder (MDD) and is associated with altered brain structure and function. It is unclear whether specific ELSs affect depression risk, cognitive function and brain structure. METHOD:This cross-sectional study included 64 antidep...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291716002403

    authors: Saleh A,Potter GG,McQuoid DR,Boyd B,Turner R,MacFall JR,Taylor WD

    更新日期:2017-01-01 00:00:00

  • Reduction in the occurrence of distressing involuntary memories following propranolol or hydrocortisone in healthy women.

    abstract:BACKGROUND:Pharmacological treatments targeting the neuroendocrine stress response may hold special promise in secondary prevention of posttraumatic stress disorder (PTSD). However, findings from clinical trials have been inconsistent and the efficacy of specific drugs, their temporal window of efficacy, effective dose...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719001028

    authors: Kamboj SK,Gong AT,Sim Z,Rashid AA,Baba A,Iskandar G,Das RK,Curran HV

    更新日期:2020-05-01 00:00:00

  • Common mental disorders in young adults born late-preterm.

    abstract:BACKGROUND:Results of adulthood mental health of those born late-preterm (34 + 0-36 + 6 weeks + days of gestation) are mixed and based on national registers. We examined if late-preterm birth was associated with a higher risk for common mental disorders in young adulthood when using a diagnostic interview, and if this ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291716000830

    authors: Heinonen K,Kajantie E,Pesonen AK,Lahti M,Pirkola S,Wolke D,Lano A,Sammallahti S,Lahti J,Andersson S,Eriksson JG,Raikkonen K

    更新日期:2016-07-01 00:00:00

  • The set-shifting profiles of anorexia nervosa and autism spectrum disorder using the Wisconsin Card Sorting Test: a systematic review and meta-analysis.

    abstract::Difficulties in set-shifting are commonly reported in both autism spectrum disorder (ASD) and anorexia nervosa (AN) populations. Despite this, it is not known whether this cognitive profile persists across different ages, or whether the profiles seen in ASD and AN are comparable. This systematic review and meta-analys...

    journal_title:Psychological medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1017/S0033291716000581

    authors: Westwood H,Stahl D,Mandy W,Tchanturia K

    更新日期:2016-07-01 00:00:00

  • On establishing the validity of 'objective' data: can we rely on cross-interview agreement?

    abstract::It has been proposed that a high level of agreement between informants' reports about events and happenings ('objective' data) is a sound basis for establishing (a) the validity of the measure which is based on the reports, and (b) the nature of objective reality. In this paper it is argued that such agreement may not...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700047486

    authors: Platt S

    更新日期:1980-08-01 00:00:00

  • Factors associated with attempted suicide among hospitalized depressed patients.

    abstract::An attempt was made to identify background, sociodemographic and clinical variables which are associated with attempted suicide in depression. Within a sample of 308 depressed psychiatric inpatients, suicide attempters were younger than non-attempters and were identified by a pattern of chronic interpersonal maladjust...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700057007

    authors: Crook T,Raskin A,Davis D

    更新日期:1975-11-01 00:00:00

  • Predictors of premenstrual impairment among women undergoing prospective assessment for premenstrual dysphoric disorder: a cycle-level analysis.

    abstract:BACKGROUND:Women who experience significant premenstrual symptoms differ in the extent to which these symptoms cause cyclical impairment. This study clarifies the type and number of symptoms that best predict premenstrual impairment in a sample of women undergoing prospective assessment for premenstrual dysphoric disor...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291716003524

    authors: Schmalenberger KM,Eisenlohr-Moul TA,Surana P,Rubinow DR,Girdler SS

    更新日期:2017-07-01 00:00:00

  • Dissociative responses to conscious and non-conscious fear impact underlying brain function in post-traumatic stress disorder.

    abstract:BACKGROUND:Dissociative reactions in post-traumatic stress disorder (PTSD) have been regarded as strategic responses that limit arousal. Neuroimaging studies suggest distinct prefrontal responses in individuals displaying dissociative and hyperarousal responses to threat in PTSD. Increased prefrontal activity may refle...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291708002742

    authors: Felmingham K,Kemp AH,Williams L,Falconer E,Olivieri G,Peduto A,Bryant R

    更新日期:2008-12-01 00:00:00

  • Prospective study of family adversity and maladaptive parenting in childhood and borderline personality disorder symptoms in a non-clinical population at 11 years.

    abstract:BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291712000542

    authors: Winsper C,Zanarini M,Wolke D

    更新日期:2012-11-01 00:00:00

  • Factors affecting the success of community placement: the TAPS project 26.

    abstract::Long-stay patients who were discharged from Friern and Claybury hospitals during the 6-year period between September 1985 and August 1991 were followed up for at least 1 year and the details of all readmissions were recorded. Of the 615 hospital leavers, some 178 (29%) were readmitted at some time during the follow-up...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700035595

    authors: Gooch C,Leff J

    更新日期:1996-05-01 00:00:00

  • Social anxiety disorder and alcohol use disorder co-morbidity in the National Epidemiologic Survey on Alcohol and Related Conditions.

    abstract:BACKGROUND:To assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States. METHOD:Data came from a large representative sample of the US population. F...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709991231

    authors: Schneier FR,Foose TE,Hasin DS,Heimberg RG,Liu SM,Grant BF,Blanco C

    更新日期:2010-06-01 00:00:00

  • The neural basis of consciousness.

    abstract::Consciousness has evolved and is a feature of all animals with sufficiently complex nervous systems. It is, therefore, primarily a problem for biology, rather than physics. In this review, I will consider three aspects of consciousness: level of consciousness, whether we are awake or in a coma; the contents of conscio...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719002204

    authors: Frith CD

    更新日期:2019-09-04 00:00:00

  • Neurocognitive functioning in bulimia nervosa: the role of neuroendocrine, personality and clinical aspects.

    abstract:BACKGROUND:Studies investigating neurocognitive impairment in subjects with eating disorders (EDs) have reported heterogeneous patterns of impairment and, in some instances, no dysfunction. The present study aimed to define the pattern of neurocognitive impairment in a large sample of bulimia nervosa (BN) patients and ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291710001303

    authors: Galderisi S,Bucci P,Mucci A,Bellodi L,Cassano GB,Santonastaso P,Erzegovesi S,Favaro A,Mauri M,Monteleone P,Maj M

    更新日期:2011-04-01 00:00:00