Effects of early life stress on depression, cognitive performance and brain morphology.

abstract：:Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits such as memory and concentration problems tend to persist after mood symptoms recover. Improving c...

journal_title：Psychological medicine

authors： Kaser M,Zaman R,Sahakian BJ

更新日期：2017-04-01 00:00:00

abstract：:Seventy-six women, with a mean age of 35.7 years, who reported premenstrual craving for sweet foods in a retrospective questionnaire, were assessed prospectively with a pre- and post-menstrual eating questionnaire and daily ratings of craving, mood, irritability and breast tenderness over two menstrual cycles. In 72% ...

journal_title：Psychological medicine

authors： Bancroft J,Cook A,Williamson L

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Rumination is an important cognitive risk factor for onset and relapse of depression. However, no studies have employed a dimensional approach in investigating the neural correlates of rumination and the relationship with depression. METHOD:Non-clinical healthy subjects (n = 306), who completed the classica...

journal_title：Psychological medicine

authors： Wang K,Wei D,Yang J,Xie P,Hao X,Qiu J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that depressed patients are impaired in their ability to shift attention from one emotional category to another, but whether this shifting deficit is more evident ...

journal_title：Psychological medicine

authors： Murphy FC,Michael A,Sahakian BJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Understanding the pathways to psychiatric care and recognition of delay points are crucial for the development of interventions that aim to improve access to mental health-care services. METHOD:Over a 2-month period in 2003, a total of 1044 patients at the commencement of new episodes of care at Amanuel Spe...

journal_title：Psychological medicine

authors： Bekele YY,Flisher AJ,Alem A,Baheretebeb Y

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Minor stresses measured in daily life have repeatedly been associated with increased momentary psychotic experiences, both in individuals with psychotic disorders and in persons who are genetically at an increased risk for these disorders. Severe hearing impairment (SHI) is an environmental risk factor for p...

journal_title：Psychological medicine

authors： Gevonden MJ,Myin-Germeys I,van den Brink W,van Os J,Selten JP,Booij J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The potential effects of antipsychotic drugs on brain structure represent a key factor in understanding neuroanatomical changes in psychosis. This review addresses two issues: (1) do antipsychotic medications induce changes in total or regional human brain volumes and (2) do such effects depend on antipsycho...

journal_title：Psychological medicine

authors： Navari S,Dazzan P

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:The assessment of inter-regional functional connectivity (FC) has allowed for the description of the putative mechanism of action of treatments such as deep brain stimulation (DBS) of the nucleus accumbens in patients with obsessive-compulsive disorder (OCD). Nevertheless, the possible FC alterations of othe...

journal_title：Psychological medicine

authors： Cano M,Alonso P,Martínez-Zalacaín I,Subirà M,Real E,Segalàs C,Pujol J,Cardoner N,Menchón JM,Soriano-Mas C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Somatoform disorders are costly for society in terms of increased healthcare expenditure. Patients' illness perceptions have been found to play a role in somatoform disorders. However, it is unclear whether illness perceptions predict higher health costs in these patients. METHOD:A total of 1785 primary car...

journal_title：Psychological medicine

authors： Frostholm L,Petrie KJ,Ornbøl E,Fink P

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We examined the prevalence of self-perceived respiratory symptoms (SRS) in the absence of any objective findings of respiratory pathology, and the association of such prevalence with psychological factors and healthcare use in the general population. METHODS:The study was conducted among a nationally repres...

journal_title：Psychological medicine

authors： Selinheimo S,Vasankari T,Jokela M,Kanervisto M,Pirkola S,Suvisaari J,Paunio T

更新日期：2019-01-01 00:00:00

abstract：:Psychiatric disorders are studied at multiple levels, but there is no agreement on how these levels are related to each other, or how they should be understood in the first place. In this paper, I provide an account of levels and their relationships that is suited for psychopathology, drawing from recent debates in ph...

journal_title：Psychological medicine

authors： Eronen MI

更新日期：2019-09-24 00:00:00

abstract：:A consecutive series of 45 female bulimic patients treated by one of us was followed four to six years after termination of treatment. Thirty-five (78%) were successfully followed, six refused to participate in the study and four were untraced. At least seven (16%) had diagnosable bulimia nervosa at follow-up, and at ...

journal_title：Psychological medicine

authors： Hsu LK,Sobkiewicz TA

更新日期：1989-11-01 00:00:00

abstract：:We measured multiple dimensions of distress among spouses (N = 440) of patients hospitalized for serious illness or elective surgery and compared the course of distress over 2 years of follow-up among five groups according to whether and when spouses were bereaved. Distress was related to the severity of the patient's...

journal_title：Psychological medicine

authors： Hays JC,Kasl SV,Jacobs SC

更新日期：1994-11-01 00:00:00

abstract：:Ten depressed patients were assessed on an auditory signal detection task; testing was repeated on remission. The patients' clinical state was monitored by means of the Hamilton rating scale and the Beck Depression Inventory. The task was performed under three conditions: 2 button (Yes/No); 1 button (Yes); 1 button (N...

journal_title：Psychological medicine

authors： Malone JR,Hemsley DR

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Outcome studies of chronic fatigue, neurasthenia and other unexplained fatigue syndromes are few and have been carried out in developed Western countries. This paper aimed to study the outcome of unexplained fatigue syndromes in an international primary care sample and to identify risk factors for persistenc...

journal_title：Psychological medicine

authors： Skapinakis P,Lewis G,Mavreas V

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

journal_title：Psychological medicine

authors： Wheeldon TJ,Robertson C,Eagles JM,Reid IC

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Feedback learning is essential for behavioral development. We investigated feedback learning in relation to behavior problems after pediatric traumatic brain injury (TBI). METHOD:Children aged 6-13 years diagnosed with TBI (n = 112; 1.7 years post-injury) were compared with children with traumatic control (...

journal_title：Psychological medicine

authors： Königs M,van Heurn LW,Vermeulen RJ,Goslings JC,Luitse JS,Poll-Thé BT,Beelen A,van der Wees M,Kemps RJ,Catsman-Berrevoets CE,Luman M,Oosterlaan J

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Spontaneous movement disorders (SMDs), such as spontaneous dyskinesia and parkinsonism, have been described in patients with schizophrenia who have never been treated with antipsychotic medication. Their presence has been documented extensively in chronic schizophrenia but not at the time of illness onset. ...

journal_title：Psychological medicine

authors： Pappa S,Dazzan P

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Cannabis use is associated with altered neurocognitive functioning in severe mental disorders, but data are still inconclusive and there are no studies of bipolar disorder. The aim of this study was to investigate the association between cannabis use and neurocognition in bipolar disorder compared with schiz...

journal_title：Psychological medicine

authors： Ringen PA,Vaskinn A,Sundet K,Engh JA,Jónsdóttir H,Simonsen C,Friis S,Opjordsmoen S,Melle I,Andreassen OA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Mental disorders often begin during the formative years of education. They may disrupt education and lead to social underachievement. METHODS:We examined the impact of mental disorders treated in hospital (ages 16-29) on educational attainment up to 31 years in the Northern Finland 1966 Birth Cohort (N = 10...

journal_title：Psychological medicine

authors： Isohanni I,Jones PB,Järvelin MR,Nieminen P,Rantakallio P,Jokelainen J,Croudace TJ,Isohanni M

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:. A variety of factors are related to compliance with medication in schizophrenia, but little attention has been paid to the role of families. Carers' knowledge or expressed emotion (EE) may be related to compliance. The aim of the present study was to evaluate the relevance of these two factors, as well as ...

journal_title：Psychological medicine

authors： Sellwood W,Tarrier N,Quinn J,Barrowclough C

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:This study aimed to explore the impacts of COVID-19 outbreak on mental health status in general population in different affected areas in China. METHODS:This was a comparative study including two groups of participants: (1) general population in an online survey in Ya'an and Jingzhou cities during the COVID...

journal_title：Psychological medicine

authors： Ran MS,Gao R,Lin JX,Zhang TM,Chan SKW,Deng XP,Zhang BZ,Zhang XF,Huang GP,Pu DS,Bai JZ,Xu LX,Liu B

更新日期：2020-12-10 00:00:00

abstract：:Principal component analysis was applied to data relating to depressive experiences collected from a general population sample. The structure of depression found in the general population showed strong similarities to that found in the psychiatric population. There were, however, important differences. Four substantia...

journal_title：Psychological medicine

authors： Cooke DJ

更新日期：1980-08-01 00:00:00

abstract：:Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...

journal_title：Psychological medicine

authors： Mindham RH,Marsden CD,Parkes JD

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed. METHOD:Antecedent, concurrent and predictive markers of construct validity were examined for three models of PDs: the Five-Factor Model (FFM), the...

journal_title：Psychological medicine

authors： Morey LC,Hopwood CJ,Gunderson JG,Skodol AE,Shea MT,Yen S,Stout RL,Zanarini MC,Grilo CM,Sanislow CA,McGlashan TH

更新日期：2007-07-01 00:00:00

abstract：:The age of onset in bipolar affective disorder was determined in 200 hospitalized patients. The mean age of their first affective syndrome was 28.3 years, and the mean age of first hospitalization was 30.8 years. However, the median age for first affective syndrome was 23 years (26 years for first hospitalization), an...

journal_title：Psychological medicine

authors： Joyce PR

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Research on the subject of insight has been hampered by difficulties in definition and reliable measurement. METHODS:We compared several rating scales to measure insight on a group of 33 psychotic patients as well as assessing patients' psychopathology, clinical characteristics and cognitive functioning. R...

journal_title：Psychological medicine

authors： Sanz M,Constable G,Lopez-Ibor I,Kemp R,David AS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...

journal_title：Psychological medicine

authors： Kuepper R,van Os J,Lieb R,Wittchen HU,Henquet C

更新日期：2011-10-01 00:00:00

abstract：:The CANTAB battery of neuropsychological tests was used to compare the performance of 28 patients with unipolar depression with that of 22 age and IQ matched controls. The patients were impaired on almost all tests studied with deficits in pattern and spatial recognition memory, matching to sample, spatial span, spati...

journal_title：Psychological medicine

authors： Elliott R,Sahakian BJ,McKay AP,Herrod JJ,Robbins TW,Paykel ES

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The neurodevelopmental model of psychosis was established over 30 years ago; however, the developmental influence on psychotic symptom expression - how age affects clinical presentation in first-episode psychosis - has not been thoroughly investigated. METHODS:Using generalized additive modeling, which allo...

journal_title：Psychological medicine

authors： Bridgwater M,Bachman P,Tervo-Clemmens B,Haas G,Hayes R,Luna B,Salisbury DF,Jalbrzikowski M

更新日期：2020-10-06 00:00:00