Abstract:
BACKGROUND:Previous research has shown that adults with intellectual disability (ID) may be more at risk of developing dementia in old age than expected. However, the effect of age and ID severity on dementia prevalence rates has never been reported. We investigated the predictions that older adults with ID should have high prevalence rates of dementia that differ between ID severity groups and that the age-associated risk should be shifted to a younger age relative to the general population. METHOD:A two-staged epidemiological survey of 281 adults with ID without Down syndrome (DS) aged 60 years; participants who screened positive with a memory task, informant-reported change in function or with the Dementia Questionnaire for Persons with Mental Retardation (DMR) underwent a detailed assessment. Diagnoses were made by psychiatrists according to international criteria. Prevalence rates were compared with UK prevalence and European consensus rates using standardized morbidity ratios (SMRs). RESULTS:Dementia was more common in this population (prevalence of 18.3%, SMR 2.77 in those aged 65 years). Prevalence rates did not differ between mild, moderate and severe ID groups. Age was a strong risk factor and was not influenced by sex or ID severity. As predicted, SMRs were higher for younger age groups compared to older age groups, indicating a relative shift in age-associated risk. CONCLUSIONS:Criteria-defined dementia is 2-3 times more common in the ID population, with a shift in risk to younger age groups compared to the general population.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Strydom A,Hassiotis A,King M,Livingston Gdoi
10.1017/S0033291708003334subject
Has Abstractpub_date
2009-01-01 00:00:00pages
13-21issue
1eissn
0033-2917issn
1469-8978pii
S0033291708003334journal_volume
39pub_type
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