Abstract:
:Fifty patients with bulimia nervosa were followed up for a minimum length of 5 years. Standardized interviews, observer-rated instruments and self-rated questionnaires were employed both at entry and at completion of the follow-up period. After tracing, the positive response rate was 72%; one patient had died. At the time of follow-up 31% of those traced had made a complete recovery and 25% still fulfilled diagnostic criteria for bulimia nervosa. Judged on behavioural symptoms 47.2% of responders had a 'good' outcome. Good outcome was associated with fewer social problems, higher social class, and a significant improvement in eating attitudes at follow-up. All outcome groups reported a reduction of interference by symptoms in other areas of life, and an improvement in mood state. No factors, including those described in previous studies, were identified which predicted outcome.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Johnson-Sabine E,Reiss D,Dayson Ddoi
10.1017/s0033291700038526subject
Has Abstractpub_date
1992-11-01 00:00:00pages
951-9issue
4eissn
0033-2917issn
1469-8978journal_volume
22pub_type
杂志文章abstract:BACKGROUND:Results of adulthood mental health of those born late-preterm (34 + 0-36 + 6 weeks + days of gestation) are mixed and based on national registers. We examined if late-preterm birth was associated with a higher risk for common mental disorders in young adulthood when using a diagnostic interview, and if this ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291716000830
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Preparing for potentially threatening events in the future is essential for survival. Anticipating the future to be unpleasant is also a cognitive key feature of depression. We hypothesized that 'pessimism'-related emotion processing would characterize brain activity in major depression.MethodDuring function...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991073
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:There is considerable debate surrounding the effective measurement of DSM-IV symptoms used to assess manic disorders in epidemiological samples. METHOD:Using two nationally representative datasets, the National Epidemiological Survey of Alcohol and Related Conditions (NESARC, n=43,093 at wave 1, n=34,653 at...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709992005
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Exposure to stressful life events increases the risk of developing a psychotic disorder. Moreover, increased reactivity to stress seems to represent part of the vulnerability for psychosis. This study aimed to investigate whether a functional polymorphism in the catechol-O-methyltransferase (COMT Val(158)Met...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291707001080
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Maladaptive learning linking environmental food cues to high-palatability food reward plays a central role in overconsumption in obesity and binge eating disorders. The process of memory reconsolidation offers a mechanism to weaken such learning, potentially ameliorating over-eating behaviour. Here we invest...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171900312X
更新日期:2021-01-01 00:00:00
abstract::Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression do not specifically target cognition. Neurocognitive deficits such as memory and concentration problems tend to persist after mood symptoms recover. Improving c...
journal_title:Psychological medicine
pub_type: 社论
doi:10.1017/S0033291716003123
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Chronic fatigue is a common condition, frequently presenting in primary care. The aim of this study was to compare the cost-effectiveness of cognitive behavioural therapy (CBT) and graded exercise therapy (GET), and to compare therapy with usual care plus a self-help booklet (BUC). METHOD:Patients drawn fro...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291704001928
更新日期:2004-08-01 00:00:00
abstract::The Eating Attitudes Test (EAT) and General Health Questionnaire (GHQ) have been validated in an unselected population of 15-year-old South London schoolgirls. Scores on the questionnaires were compared with the results of standard interview. The EAT was found to be an efficient screening instrument for abnormal eatin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700047991
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the original atypical antipsychotic, clozapine. Its clinical efficacy has already been demonstrated at multiple fixed doses (150-750 mg/day) and has been suggested to be comparable with haloperidol (1...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1017/s0033291799001476
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章
doi:10.1017/s0033291704003551
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:We investigated whether schizophrenic subjects are impaired in non-routine behaviour because of the dysfunction of a general executive component labelled, in neuropsychological terms, the supervisory system. METHODS:A specific verbal sequencing test was designed for this purpose. Subjects had to perform seq...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291797005515
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined. METHOD:A total of 167 consecutive patients admitted to the stroke units of two university hospitals after an ischaemic stroke and 109 controls received extensive m...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291705006173
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:The overlap between anxiety and major depressive disorder (MDD), the increased risk for depression and anxiety in offspring of depressed parents, the sequence of onset with anxiety preceding MDD, and anxiety as a predictor of depression are well established. The specificity of anxiety disorders in these rela...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708002894
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Impaired spatial working memory (SWM) is a robust feature of schizophrenia and has been linked to the risk of developing psychosis in people with an at-risk mental state (ARMS). We used functional magnetic resonance imaging (fMRI) to examine the neural substrate of SWM in the ARMS and in patients who had jus...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291710000280
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:To date, magnetic resonance imaging (MRI) has made little impact on the diagnosis and monitoring of psychoses in individual patients. In this study, we used a support vector machine (SVM) whole-brain classification approach to predict future illness course at the individual level from MRI data obtained at th...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002005
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:We report on the epidemiology of post-traumatic stress disorder (PTSD) in the Australian community, including information on lifetime exposure to trauma, 12-month prevalence of PTSD, sociodemographic correlates and co-morbidity. METHODS:Data were obtained from a stratified sample of 10,641 participants as p...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004287
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Previous research has found that depression is a major cause of memory complaints. However, there is evidence that memory complaints also weakly predict cognitive decline and dementia. The present study examined a range of possible determinants of memory complaints, covering psychiatric and personality facto...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704003162
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:The objective was to describe patients presenting themselves at emergency-care settings following a suicide attempt in eight culturally different sites [Campinas (Brazil), Chennai (India), Colombo (Sri Lanka), Durban (South Africa), Hanoi (Viet Nam), Karaj (Iran), Tallinn (Estonia), and Yuncheng, (China)]. ...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291705005416
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Somatoform disorders are costly for society in terms of increased healthcare expenditure. Patients' illness perceptions have been found to play a role in somatoform disorders. However, it is unclear whether illness perceptions predict higher health costs in these patients. METHOD:A total of 1785 primary car...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171400035X
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Older adults have the lowest prevalence and incidence of major depressive disorder, although it has been hypothesized that this finding is due in part to differences in expression of psychopathology in later life. The aim of this study was to examine variation in depressive symptomatology in the general popu...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S003329171200027X
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:The relationship between recurrent major depression (MD) in women and suicidality is complex. We investigated the extent to which patients who suffered with various forms of suicidal symptomatology can be distinguished from those subjects without such symptoms. METHOD:We examined the clinical features of th...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329171200058X
更新日期:2012-12-01 00:00:00
abstract::In this paper four principal topics are addressed: (a) the policy and political contexts in which demands arise for cost information; (b) the nature and phasing of those demands; (c) the basic rules of empirical costs research for meeting those demands; and (d) concomitant implications for the design, execution and in...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/s003329170003659x
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:Generalized anxiety disorder is a common condition of excessive worry and tension which tends to run a chronic course associated with significant psychiatric and medical problems. Cognitive behaviour therapy (CBT) has been shown to be of clinical value in about 50% of cases with treatment gains maintained ov...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0033291702007079
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder which frequently persists into adulthood. The primary goal of the current study was to (a) investigate attentional functions of stimulant medication-naïve adults with ADHD, and (b) investigate the effects of 6 weeks of methylphe...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291718003628
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The processing of facial emotion involves a distributed network of limbic and paralimbic brain structures. Many of these regions are also implicated in the pathophysiology of mood disorders. Behavioural data indicate that depressed subjects show a state-related positive recognition bias for faces displaying ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704002557
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Clinical intuition suggests that personality disorders hinder the treatment of depression, but research findings are mixed. One reason for this might be the way in which current assessment measures conflate general aspects of personality disorders, such as overall severity, with specific aspects, such as sty...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000361X
更新日期:2020-10-08 00:00:00
abstract:BACKGROUND:Parental characteristics and practices predict borderline personality disorder (BPD) symptoms in children. However, it is difficult to disentangle whether these effects are genetically or environmentally mediated. The present study examines the contributions of genetic and environmental influences by compari...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001260
更新日期:2020-06-01 00:00:00
abstract::Hypothalamic-pituitary-adrenal axis function was investigated in 72 patients with primary depression. Forty-four per cent of the patients demonstrated abnormal suppression of their cortisol levels after a 1 mg overnight dexamethasone suppression test. Patients with abnormal suppression ('non-suppressors') were not cle...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700019711
更新日期:1984-11-01 00:00:00
abstract::One hundred and nineteen primiparae, who were routinely attending ante-natal clinics, were interviewed repeatedly between the 12th and 36th weeks of their pregnancies. The incidence of depression was highest in the first trimester and, overall, about a fifth of the sample was found to be suffering from clinically sign...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700018912
更新日期:1978-11-01 00:00:00
abstract:BACKGROUND:There is still a relative paucity of information about the long-term course of depression. METHODS:Consecutive patients admitted to a teaching hospital psychiatry unit with symptoms of depression, previously assessed at 6 months and 2, 5 and 15 years after index admission, were reviewed at 25 years (N = 49,...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291701004743
更新日期:2001-11-01 00:00:00