Visual working memory encoding in schizophrenia and first-degree relatives: neurofunctional abnormalities and impaired consolidation.

abstract：BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...

journal_title：Psychological medicine

authors： Kuepper R,van Os J,Lieb R,Wittchen HU,Henquet C

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) has been called one of the signature injuries of the Iraq War. In this review prevalence estimates of PTSD are summarized and discrepancies are discussed in relation to methodological differences between studies. METHOD:We searched for population-based studies with a mi...

journal_title：Psychological medicine

authors： Sundin J,Fear NT,Iversen A,Rona RJ,Wessely S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:There is evidence that patients with chronic fatigue syndrome (CFS) have mild hypocortisolism. The clinical significance of this is unclear. We aimed to determine whether hypocortisolism exerted any effect on the response of CFS to cognitive behavioural therapy (CBT). METHOD:We measured 24-h urinary free co...

journal_title：Psychological medicine

authors： Roberts AD,Charler ML,Papadopoulos A,Wessely S,Chalder T,Cleare AJ

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Recent neurobiological models provide a possible mechanism of daily life stress directly affecting the intensity of psychotic experiences in vulnerable individuals. In order to validate such a mechanism, the impact of daily life stress on psychosis intensity was investigated in two groups at increased risk o...

journal_title：Psychological medicine

authors： Myin-Germeys I,Delespaul P,van Os J

更新日期：2005-05-01 00:00:00

abstract：:The theory that many diseases were produced by focal infection or chronic sepsis enjoyed a brief vogue in general medicine in the first quarter of the twentieth century. This paper explores its practical applications in psychiatry, which extended well into the 1930s. The analysis focuses particularly closely on the ac...

journal_title：Psychological medicine

authors： Scull A

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Genetic influences contribute significantly to co-morbidity between conduct disorder and substance use disorders. Estimating the extent of overlap can assist in the development of phenotypes for genomic analyses. METHOD:Multivariate quantitative genetic analyses were conducted using data from 9577 individua...

journal_title：Psychological medicine

authors： Grant JD,Lynskey MT,Madden PA,Nelson EC,Few LR,Bucholz KK,Statham DJ,Martin NG,Heath AC,Agrawal A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Decreased white matter (WM) integrity in patients with psychotic disorder has been a consistent finding in diffusion tensor imaging (DTI) studies. However, the contribution of environmental risk factors to these WM alterations is rarely investigated. The current study examines whether individuals with (incre...

journal_title：Psychological medicine

authors： Domen P,Michielse S,Peeters S,Viechtbauer W,van Os J,Marcelis M,for Genetic Risk and Outcome of Psychosis (G.R.O.U.P.).

更新日期：2019-03-01 00:00:00

abstract：:Long-stay patients who were discharged from Friern and Claybury hospitals during the 6-year period between September 1985 and August 1991 were followed up for at least 1 year and the details of all readmissions were recorded. Of the 615 hospital leavers, some 178 (29%) were readmitted at some time during the follow-up...

journal_title：Psychological medicine

authors： Gooch C,Leff J

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design. METHODS:A longitudinal cohort design in an online commu...

journal_title：Psychological medicine

authors： Jaya ES,Ascone L,Lincoln TM

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:To estimate the lifetime prevalence and potential determinants of psychotic experience(s) (PEs) in the general population of Qatar - a small non-war afflicted, conservative, high-income, middle-eastern country with recent rapid urbanization including an influx of migrants. METHODS:A probability-based sample...

journal_title：Psychological medicine

authors： Khaled SM,Wilkins SS,Woodruff P

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...

journal_title：Psychological medicine

authors： Dib JE,Yaacoub HE,Ikdais WH,Atallah E,Merheb TJ,Ajaltouni J,Akkari M,Mourad M,Nasr ME,Hachem D,Kazour F,Tahan F,Haddad G,Azar J,Zoghbi M,Haddad C,Hallit S,Adams CE

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Childhood trauma is a non specific risk factor for adult eating disorders (ED), and the hypothalamic-pituitary-adrenal (HPA) axis seems to mediate such a risk. Here we explored the impact of different types of childhood trauma and of traumatic load on the cortisol awakening response (CAR) of women with anore...

journal_title：Psychological medicine

authors： Monteleone AM,Monteleone P,Volpe U,De Riso F,Fico G,Giugliano R,Nigro M,Maj M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavi...

journal_title：Psychological medicine

authors： Blonigen DM,Hicks BM,Krueger RF,Patrick CJ,Iacono WG

更新日期：2005-05-01 00:00:00

abstract：:The increase in plasma prolactin which follows intravenous administration of L-tryptophan (LTP) was used to assess changes in brain 5-hydroxytryptamine (5-HT) function in normal male and female subjects, following a three week period of dieting. In women, but not men, there was a marked increase in the prolactin respo...

journal_title：Psychological medicine

authors： Goodwin GM,Fairburn CG,Cowen PJ

更新日期：1987-11-01 00:00:00

abstract：:Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...

journal_title：Psychological medicine

authors： Mindham RH,Marsden CD,Parkes JD

更新日期：1976-02-01 00:00:00

abstract：:The incidence of cavum septum pellucidum (CSP), which has been widely regarded as a developmental anomaly of little clinical importance in neuropathology, was examined in 113 patients with affective disorders (69 with bipolar disorder and 44 with major depression), 40 schizophrenic patients, and 92 control subjects by...

journal_title：Psychological medicine

authors： Shioiri T,Oshitani Y,Kato T,Murashita J,Hamakawa H,Inubushi T,Nagata T,Takahashi S

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:To assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States. METHOD:Data came from a large representative sample of the US population. F...

journal_title：Psychological medicine

authors： Schneier FR,Foose TE,Hasin DS,Heimberg RG,Liu SM,Grant BF,Blanco C

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The clinical picture of schizophrenia is frequently worsened by manifestations of impulsivity. However, the neural correlates of impulsivity in this disorder are poorly known. Although impulsivity has been related to disturbances of the neural processes underlying response inhibition, no studies have yet exa...

journal_title：Psychological medicine

authors： Kaladjian A,Jeanningros R,Azorin JM,Anton JL,Mazzola-Pomietto P

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Cognitive impairment and negative symptoms are two of the primary features of schizophrenia associated with poor social functioning. We examined the relationships between clinical characteristics, specific cognitive abilities and social skills performance in middle-aged and older out-patients with schizophre...

journal_title：Psychological medicine

authors： Sitzer DI,Twamley EW,Patterson TL,Jeste DV

更新日期：2008-05-01 00:00:00

abstract：:This study investigates the basis of individual variation in exposure to stressful life events (SLEs). A population based sample of 547 MZ and 390 DZ female-female twin pairs, aged between 17 and 55 years, were surveyed by two structured interviews, separated by at least 1 year, that enquired about SLEs experienced du...

journal_title：Psychological medicine

authors： Foley DL,Neale MC,Kendler KS

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Compassion-focused therapy (CFT) is a relatively novel form of psychotherapy that was developed for people who have mental health problems primarily linked to high shame and self-criticism. The aim of this early systematic review was to draw together the current research evidence of the effectiveness of CFT ...

journal_title：Psychological medicine

authors： Leaviss J,Uttley L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological pathways. Of candidate biological pathways for schizophrenia (SZ), the cell adhesion molecule (CAM...

journal_title：Psychological medicine

authors： Hargreaves A,Anney R,O'Dushlaine C,Nicodemus KK,Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ).,Wellcome Trust Case Control Consortium 2.,Gill M,Corvin A,Morris D,Donohoe G

更新日期：2014-07-01 00:00:00

abstract：:Patients suffering from manic-depressive psychosis, manic type (ICD 296.0), were treated with lithium carbonate and randomly allocated to two groups, one received digoxin and the other matching placebo for 7 days. Severity of mania was rated by psychiatrists on the Manic Rating Scale and Analogue Line on days 0 and 7 ...

journal_title：Psychological medicine

authors： Chambers CA,Smith AH,Naylor GJ

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Controlled prospective studies of the simultaneous long-term outcome of several mental disorders are rare. This study sought to determine if there were important differences between the outcome of anxiety and depressive disorders after 12 years and to examine their main predictors. METHOD:A cohort of 210 pe...

journal_title：Psychological medicine

authors： Tyrer P,Seivewright H,Johnson T

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Sibling resemblance in crime may be due to genetic relatedness, shared environment, and/or the interpersonal influence of siblings on each other. This latter process can be understood as a type of 'peer effect' in that it is based on social learning between individuals occupying the same status in the social...

journal_title：Psychological medicine

authors： Mikkonen J,Savolainen J,Aaltonen M,Martikainen P

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Although depression and mania are often assumed to be polar opposites, studies have shown that, in patients with bipolar disorder, they are weakly positively correlated and vary somewhat independently over time. Thus, when investigating relationships between specific psychological processes and specific symp...

journal_title：Psychological medicine

authors： Pavlickova H,Varese F,Turnbull O,Scott J,Morriss R,Kinderman P,Paykel E,Bentall RP

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. ...

journal_title：Psychological medicine

authors： Lowe SR,Ratanatharathorn A,Lai BS,van der Mei W,Barbano AC,Bryant RA,Delahanty DL,Matsuoka YJ,Olff M,Schnyder U,Laska E,Koenen KC,Shalev AY,Kessler RC

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Neuroanatomical abnormalities in first-episode psychosis (FEP) tend to be subtle and widespread. The vast majority of previous studies have used small samples, and therefore may have been underpowered. In addition, most studies have examined participants at a single research site, and therefore the results m...

journal_title：Psychological medicine

authors： Vieira S,Gong Q,Scarpazza C,Lui S,Huang X,Crespo-Facorro B,Tordesillas-Gutierrez D,de la Foz VO,Setien-Suero E,Scheepers F,van Haren NEM,Kahn R,Reis Marques T,Ciufolini S,Di Forti M,Murray RM,David A,Dazzan P,McGuire

更新日期：2019-12-20 00:00:00

abstract：BACKGROUND:Hierarchical structural models of psychopathology rarely extend to obsessive-compulsive spectrum disorders. The current study sought to examine the higher-order structure of the obsessive-compulsive and related disorders (OCRDs) in DSM-5: obsessive-compulsive disorder (OCD), hoarding disorder (HD), body dysm...

journal_title：Psychological medicine

authors： Snorrason I,Beard C,Peckham AD,Björgvinsson T

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Both low intelligence and low emotional control have previously been linked to a higher risk of suicide, but it is unknown whether the associations apply consistently over the life course. METHODS:The study was based on data on intelligence and emotional control, collected from 48 738 Swedish men conscripte...

journal_title：Psychological medicine

authors： Hansson Bittár N,Falkstedt D,Sörberg Wallin A

更新日期：2020-10-01 00:00:00