A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect.

Abstract:

BACKGROUND:Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design. METHODS:A longitudinal cohort design in an online community sample (N = 962) from Germany, Indonesia, and the USA was used. NSS, negative affect and positive symptoms were measured at four time-points (T0-T3) over a 1-year period. Cross-lagged panel and longitudinal mediation analyses with structural equation modeling were used to test the temporal mediation. RESULTS:Independent cross-lagged panel models showed a significant unidirectional longitudinal path from NSS to positive symptoms (T2-T3, β = 0.18, p < 0.01) and bidirectional longitudinal associations from NSS to negative affect (T0-T1, γ = 0.14, p < 0.01) and vice versa (T0-T1, γ = 0.19, p < 0.01). There was also a significant indirect pathway from NSS at baseline via negative affect at T1 and T2 to positive symptoms at T3 (unstandardized indirect effect coefficient = 0.020, p < 0.05, BCa CI 0.004-0.035), indicating mediation. CONCLUSIONS:Our findings support the postulated affective pathway from NSS to positive symptoms via negative affect. Specifically, our data indicate that NSS and negative affect influence each other and build up over the course of several months before leading on to positive symptoms. We conclude that interrupting this process by targeting NSS and negative affect early in the process could be a promising strategy to prevent the exacerbation of positive symptoms.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Jaya ES,Ascone L,Lincoln TM

doi

10.1017/S003329171700277X

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

1299-1307

issue

8

eissn

0033-2917

issn

1469-8978

pii

S003329171700277X

journal_volume

48

pub_type

杂志文章,多中心研究
  • Recollection memory deficits in patients with major depressive disorder predicted by past depressions but not current mood state or treatment status.

    abstract:BACKGROUND:Neuropsychological studies have suggested that memory systems reliant on medial temporal lobe structures are impaired in patients with depression. There is less data regarding whether this impairment is specific to recollection memory systems, and whether clinical features predict impairment. This study soug...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291701004834

    authors: MacQueen GM,Galway TM,Hay J,Young LT,Joffe RT

    更新日期:2002-02-01 00:00:00

  • Psychological strength assessed in late adolescence and risk for criminal behavior: a Swedish prospective cohort and twin analysis.

    abstract:BACKGROUND:Certain personality traits predispose to criminal behavior (CB). We further clarify this relationship in a Swedish national sample. METHOD:Psychological strength (PS) was assessed on a nine-point scale at personal interview in 1 653 721 Swedish men aged 18-20 years. We examined the association between PS an...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291715001403

    authors: Kendler KS,Lönn SL,Lichtenstein P,Sundquist J,Sundquist K

    更新日期:2016-01-01 00:00:00

  • Impulsivity in disorders of food and drug misuse.

    abstract:BACKGROUND:Evidence suggests some overlap between the pathological use of food and drugs, yet how impulsivity compares across these different clinical disorders remains unclear. Substance use disorders are commonly characterized by elevated impulsivity, and impulsivity subtypes may show commonalities and differences in...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714001834

    authors: Mole TB,Irvine MA,Worbe Y,Collins P,Mitchell SP,Bolton S,Harrison NA,Robbins TW,Voon V

    更新日期:2015-03-01 00:00:00

  • The seasonal incidence of mania and its relationship to climatic variables.

    abstract::Monthly hospital admission rates (HA) for mania were classified by sex, type of admission (first, or re-admission) and by country (England and Wales or Scotland). Of the 8 classes thus created, all but one showed a statistically significant annual cycle with a peak in Summer and trough in Winter. There was no signific...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s003329170001610x

    authors: Myers DH,Davies P

    更新日期:1978-08-01 00:00:00

  • Dimensional structure of bodily panic attack symptoms and their specific connections to panic cognitions, anxiety sensitivity and claustrophobic fears.

    abstract:BACKGROUND:Previous studies of the dimensional structure of panic attack symptoms have mostly identified a respiratory and a vestibular/mixed somatic dimension. Evidence for additional dimensions such as a cardiac dimension and the allocation of several of the panic attack symptom criteria is less consistent. Clarifyin...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0033291714002803

    authors: Drenckhan I,Glöckner-Rist A,Rist F,Richter J,Gloster AT,Fehm L,Lang T,Alpers GW,Hamm AO,Fydrich T,Kircher T,Arolt V,Deckert J,Ströhle A,Wittchen HU,Gerlach AL

    更新日期:2015-06-01 00:00:00

  • Systematic review of multi-symptom conditions in Gulf War veterans.

    abstract:BACKGROUND:Gulf War veterans have a number of health complaints. We therefore decided to carry out a systematic review to identify and summarize the findings from studies that have assessed multi-symptom conditions in Gulf War veterans and in an unexposed comparison group. METHOD:Studies published between January 1990...

    journal_title:Psychological medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1017/S0033291705006975

    authors: Thomas HV,Stimpson NJ,Weightman AL,Dunstan F,Lewis G

    更新日期:2006-06-01 00:00:00

  • Alcohol consumption as a risk factor for non-recovery from common mental disorder: results from the longitudinal follow-up of the National Psychiatric Morbidity Survey.

    abstract:BACKGROUND:Alcohol is commonly considered to be associated with persistence of common mental disorder (CMD; anxiety/depression). However no community-based longitudinal studies have investigated the direction of causality. METHOD:We examined the association between alcohol consumption and recovery from CMD using data ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291707002000

    authors: Haynes JC,Farrell M,Singleton N,Meltzer H,Araya R,Lewis G,Wiles NJ

    更新日期:2008-03-01 00:00:00

  • Lateral interactions in the visual cortex of patients with schizophrenia and bipolar disorder.

    abstract:BACKGROUND:Schizophrenia is associated with perceptual organization deficits and abnormal neuronal connectivity has been described in early visual areas. The purpose of this study was to investigate the functional integrity of lateral connections in early visual areas of patients with schizophrenia and type I bipolar d...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291705004381

    authors: Kéri S,Kelemen O,Benedek G,Janka Z

    更新日期:2005-07-01 00:00:00

  • Hedonic tone is associated with left supero-lateral medial forebrain bundle microstructure.

    abstract:BACKGROUND:The medial forebrain bundle (MFB) is an important pathway of the reward system. Two branches have been described using diffusion magnetic resonance imaging (MRI)-based tractography: the infero-medial MFB (imMFB) and the supero-lateral MFB (slMFB). Previous studies point to white-matter microstructural altera...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714001949

    authors: Bracht T,Doidge AN,Keedwell PA,Jones DK

    更新日期:2015-03-01 00:00:00

  • Development and feasibility assessment of a collaborative stepped care intervention for management of depression in the mental health in primary care (MeHPriC) project, Lagos, Nigeria.

    abstract:BACKGROUND:This study aimed to develop and test the feasibility of a primary care worker-led psychological intervention as the main feature of a collaborative stepped care for depression that is effective, affordable, culturally acceptable, tailored to patients' clinical condition and easily integrate-able into the pri...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291718002970

    authors: Adewuya AO,Adewumi T,Momodu O,Olibamoyo O,Adesoji O,Adegbokun A,Adeyemo S,Manuwa O,Adegbaju D

    更新日期:2019-10-01 00:00:00

  • Interaction between a history of depression and rumination on neural response to emotional faces.

    abstract:BACKGROUND:Both past depressive episodes and the personality trait of depressive rumination are strong risk factors for future depression. Depression is associated with abnormal emotional processing, which may be a neurobiological marker for vulnerability to depression. A consistent picture has yet to emerge as to how ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711000043

    authors: Thomas EJ,Elliott R,McKie S,Arnone D,Downey D,Juhasz G,Deakin JF,Anderson IM

    更新日期:2011-09-01 00:00:00

  • Psychiatric disorder in a rural and an urban population: 2. Sensitivity to loss.

    abstract::In an earlier paper we found that a model of depression developed on a sample of women in a London population was confirmed in a female population in the Outer Hebrides. Differences in the rates of onset and chronic cases between the two populations, however, suggested that the Scottish women might be more likely to b...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700052892

    authors: Prudo R,Brown GW,Harris T,Dowland J

    更新日期:1981-08-01 00:00:00

  • Prefrontal dysfunction in depressed patients performing a complex planning task: a study using positron emission tomography.

    abstract:INTRODUCTION:Patients with unipolar depression show impaired performance on the Tower of London planning task. Positron emission tomography, which has previously identified resting state blood flow abnormalities in depression, was used to investigate neural activity associated with performance of this task in depressed...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291797005187

    authors: Elliott R,Baker SC,Rogers RD,O'Leary DA,Paykel ES,Frith CD,Dolan RJ,Sahakian BJ

    更新日期:1997-07-01 00:00:00

  • Lifetime prevalence and potential determinants of psychotic experiences in the general population of Qatar.

    abstract:BACKGROUND:To estimate the lifetime prevalence and potential determinants of psychotic experience(s) (PEs) in the general population of Qatar - a small non-war afflicted, conservative, high-income, middle-eastern country with recent rapid urbanization including an influx of migrants. METHODS:A probability-based sample...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719000977

    authors: Khaled SM,Wilkins SS,Woodruff P

    更新日期:2020-05-01 00:00:00

  • Lessons learned from the psychosis high-risk state: towards a general staging model of prodromal intervention.

    abstract:BACKGROUND:The past two decades have seen exponential clinical and research interest in help-seeking individuals presenting with potentially prodromal symptoms for psychosis. However, the epidemiological validity of this paradigm has been neglected, limiting future advancements in the field. METHOD:We undertook a crit...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291713000184

    authors: Fusar-Poli P,Yung AR,McGorry P,van Os J

    更新日期:2014-01-01 00:00:00

  • Individualized prediction of dispositional worry using white matter connectivity.

    abstract:BACKGROUND:Excessive worry is a defining feature of generalized anxiety disorder and is present in a wide range of other psychiatric conditions. Therefore, individualized predictions of worry propensity could be highly relevant in clinical practice, with respect to the assessment of worry symptom severity at the indivi...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291718002763

    authors: Feng C,Cui Z,Cheng D,Xu R,Gu R

    更新日期:2019-09-01 00:00:00

  • Psychiatric aspects of railway fatalities.

    abstract::National statistics for railway fatalities in England and Wales show a reduction of train crashes and a fluctuating level of deaths, of which an increasing proportion is from suicide. A closer examination of a two-year sample from the South of England revealed a large proportion of probable suicides and a small propor...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700031469

    authors: Symonds RL

    更新日期:1985-08-01 00:00:00

  • Health problems, impairment and illnesses associated with bulimia nervosa and binge eating disorder among primary care and obstetric gynaecology patients.

    abstract:BACKGROUND:Although psychiatric patients with eating disorders are known to be at risk for a variety of health problems, relatively little is known about eating disorders and associated health problems in other populations. An epidemiological study was conducted to investigate health problems and impairment associated ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1017/s0033291701004640

    authors: Johnson JG,Spitzer RL,Williams JB

    更新日期:2001-11-01 00:00:00

  • Attributes of long-term heavy cannabis users: a case-control study.

    abstract:BACKGROUND:Although cannabis is the most widely used illicit drug in the United States, few recent American studies have examined the attributes of long-term heavy cannabis users. METHOD:Using a case-control design, we obtained psychological and demographic measures on 108 individuals, age 30-55, who had smoked cannab...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291703008560

    authors: Gruber AJ,Pope HG,Hudson JI,Yurgelun-Todd D

    更新日期:2003-11-01 00:00:00

  • Prevalence and genetic and environmental influences on anxiety disorders in 6-year-old twins.

    abstract:BACKGROUND:Prevalence of childhood anxiety disorders at specific ages and genetic etiological influences on anxiety disorders in young children have been little studied. The present study reports prevalence estimates in a community sample of 6-year-old twins, and patterns of genetic and environmental influences on thes...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291705006537

    authors: Bolton D,Eley TC,O'Connor TG,Perrin S,Rabe-Hesketh S,Rijsdijk F,Smith P

    更新日期:2006-03-01 00:00:00

  • Prevention of psychosis: moving on from the at-risk mental state to universal primary prevention.

    abstract::The value of services for those with the 'At Risk Mental State for Psychosis' (ARMS) continues to be disputed. ARMS services have provided a valuable stimulus to academic research into the transition into psychosis. Furthermore, there is currently a welcome trend to transform such clinics into youth mental health serv...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S003329172000313X

    authors: Murray RM,David AS,Ajnakina O

    更新日期:2020-09-07 00:00:00

  • Manual-assisted cognitive-behaviour therapy (MACT): a randomized controlled trial of a brief intervention with bibliotherapy in the treatment of recurrent deliberate self-harm.

    abstract:BACKGROUND:The treatment of deliberate self-harm (parasuicide) remains limited in efficacy. Despite a range of psychosocial, educational and pharmacological interventions only one approach, dialectical behaviour therapy, a form of cognitive-behaviour therapy (CBT), has been shown to reduce repeat episodes, but this is ...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s003329179800765x

    authors: Evans K,Tyrer P,Catalan J,Schmidt U,Davidson K,Dent J,Tata P,Thornton S,Barber J,Thompson S

    更新日期:1999-01-01 00:00:00

  • Personality disorder in mental handicap.

    abstract::100 randomly selected mildly or moderately mentally retarded adults were assessed for personality disorder using the Standardized Assessment of Personality devised by Mann et al. (1981). By the terms of this instrument 56% of patients showed features of abnormal personality, and in 22% this abnormality was marked, sug...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700000799

    authors: Reid AH,Ballinger BR

    更新日期:1987-11-01 00:00:00

  • Mortality in offspring of mothers with psychotic disorder.

    abstract:BACKGROUND:Previous studies suggest that offspring of mothers with psychotic disorders have an almost two-fold higher mortality risk from birth until early adulthood. We investigated predictors of mortality from late adolescence until middle age in offspring of mothers with psychotic disorders. METHOD:The Helsinki Hig...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291707002383

    authors: Suvisaari J,Häkkinen L,Haukka J,Lönnqvist J

    更新日期:2008-08-01 00:00:00

  • Alterations of empathy in mothers with a history of early life maltreatment, depression, and borderline personality disorder and their effects on child psychopathology.

    abstract:BACKGROUND:Early life maltreatment (ELM), borderline personality disorder (BPD), and major depressive disorder (MDD) have been associated with empathy deficits in different domains. Lack of maternal empathy has also been related to child behavioral problems. As ELM, BPD, and MDD often co-occur, we aimed to identify dis...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719001107

    authors: Dittrich K,Bermpohl F,Kluczniok D,Hindi Attar C,Jaite C,Fuchs A,Neukel C,Herpertz SC,Brunner R,Winter SM,Lehmkuhl U,Roepke S,Kaess M,Heim C,Boedeker K

    更新日期:2020-05-01 00:00:00

  • Pathways from assaultive violence to post-traumatic stress, depression, and generalized anxiety symptoms through stressful life events: longitudinal mediation models.

    abstract:BACKGROUND:Assaultive violence events are associated with increased risk for adverse psychiatric outcomes, including post-traumatic stress (PTS), depression, and generalized anxiety. Prior research has indicated that economic, legal, and social stressors that could follow assaultive events may explain the increased ris...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717001143

    authors: Lowe SR,Joshi S,Galea S,Aiello AE,Uddin M,Koenen KC,Cerdá M

    更新日期:2017-10-01 00:00:00

  • Facets of Conscientiousness and risk of dementia.

    abstract:BACKGROUND:Multiple studies have found Conscientiousness to be protective against dementia. The purpose of this study is to identify which specific aspects, or facets, of Conscientiousness are most protective against cognitive impairment and whether these associations are moderated by demographic factors and/or genetic...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717002306

    authors: Sutin AR,Stephan Y,Terracciano A

    更新日期:2018-04-01 00:00:00

  • Increased rates of schizophrenia among immigrants: some methodological concerns raised by Danish findings.

    abstract:BACKGROUND:Several studies during recent years have reported an increased occurrence of schizophrenia in selected immigrant groups. However, difficulties in establishing the population denominator for immigrant rates of mental disorder, selective referral for treatment, and other problems may have influenced such resul...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291797004741

    authors: Mortensen PB,Cantor-Graae E,McNeil TF

    更新日期:1997-07-01 00:00:00

  • Neuropsychological evidence of reductions on left frontal tests with hypnosis.

    abstract::Individuals with high and low susceptibility to hypnosis were compared in a baseline condition and after instructions of hypnosis on tests of anterior left and right hemispheric functions--word fluency to letter categories, word fluency to semantic categories, design fluency and bilateral finger tapping dexterity. Wit...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/s0033291700038885

    authors: Gruzelier J,Warren K

    更新日期:1993-02-01 00:00:00

  • SIDAM--A structured interview for the diagnosis of dementia of the Alzheimer type, multi-infarct dementia and dementias of other aetiology according to ICD-10 and DSM-III-R.

    abstract::The SIDAM--a new instrument for the symptomatic diagnosis and measurement of dementia according to DSM-III-R and ICD-10--is described. It comprises a brief structured clinical interview, a range of cognitive tests (e.g. including the Mini-Mental State (Folstein et al. 1975)) which constitute a short neuropsychological...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700014811

    authors: Zaudig M,Mittelhammer J,Hiller W,Pauls A,Thora C,Morinigo A,Mombour W

    更新日期:1991-02-01 00:00:00