Altered serotonin transporter binding potential in patients with obsessive-compulsive disorder under escitalopram treatment: [11C]DASB PET study.

abstract：BACKGROUND:Stress questionnaires are included in many epidemiological cohort studies but the psychometric characteristics of these questionnaires are largely unknown. The aim of this study was to describe these characteristics for two short questionnaires measuring the lifetime and past year occurrence of stress: the L...

journal_title：Psychological medicine

authors： Rosmalen JG,Bos EH,de Jonge P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Schizophrenia patients have a higher prevalence of type 2 diabetes mellitus with impaired glucose tolerance (IGT) than normals. We examined the relationship between IGT and clinical phenotypes or cognitive deficits in first-episode, drug-naïve (FEDN) Han Chinese patients with schizophrenia. METHOD:A total o...

journal_title：Psychological medicine

authors： Chen DC,Du XD,Yin GZ,Yang KB,Nie Y,Wang N,Li YL,Xiu MH,He SC,Yang FD,Cho RY,Kosten TR,Soares JC,Zhao JP,Zhang XY

更新日期：2016-11-01 00:00:00

abstract：:In an earlier paper we found that a model of depression developed on a sample of women in a London population was confirmed in a female population in the Outer Hebrides. Differences in the rates of onset and chronic cases between the two populations, however, suggested that the Scottish women might be more likely to b...

journal_title：Psychological medicine

authors： Prudo R,Brown GW,Harris T,Dowland J

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Patients with anorexia nervosa (AN) run a high risk of becoming chronically ill and of dying. In the acute phase of their illness they present with numerous physical and laboratory abnormalities. However, little is known about the long-term prognostic value of these findings or about the medical morbidity in...

journal_title：Psychological medicine

authors： Herzog W,Deter HC,Fiehn W,Petzold E

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Men sexually interested in children of a specific combination of maturity and sex tend to show some lesser interest in other categories of persons. Patterns of men's sexual interest across erotic targets' categories of maturity and sex have both clinical and basic scientific implications. METHOD:We examined...

journal_title：Psychological medicine

authors： Bailey JM,Blanchard R,Hsu KJ,Revelle W

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Neuroimaging studies have shown variance in brain response to emotional faces predicts cognitive behavioral therapy (CBT) outcome. An important next step is to determine if individual differences in neural predictors of CBT response represent distinct patient groups. METHODS:In total, 90 patients with inter...

journal_title：Psychological medicine

authors： Klumpp H,Jimmy J,Burkhouse KL,Bhaumik R,Francis J,Craske MG,Phan KL,Ajilore O

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period...

journal_title：Psychological medicine

authors： Haukvik UK,Schaer M,Nesvåg R,McNeil T,Hartberg CB,Jönsson EG,Eliez S,Agartz I

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:There is not yet consensus on the best diagnostic definition of mixed bipolar episodes. Many have suggested the DSM-III-R/-IV definition is too rigid. We propose alternative criteria using data from a large patient cohort. METHODS:We evaluated 237 manic in-patients using DSM-III-R criteria and the Scale for...

journal_title：Psychological medicine

authors： Cassidy F,Ahearn E,Murry E,Forest K,Carroll BJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiop...

journal_title：Psychological medicine

authors： Zammit S,Odd D,Horwood J,Thompson A,Thomas K,Menezes P,Gunnell D,Hollis C,Wolke D,Lewis G,Harrison G

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Mild traumatic brain injury (mTBI) is being claimed as the 'signature' injury of the Iraq war, and is believed to be the cause of long-term symptomatic ill health (post-concussional syndrome; PCS) in an unknown proportion of military personnel. METHOD:We analysed cross-sectional data from a large, randomly ...

journal_title：Psychological medicine

authors： Fear NT,Jones E,Groom M,Greenberg N,Hull L,Hodgetts TJ,Wessely S

更新日期：2009-08-01 00:00:00

abstract：:Potential cases of presenile dementia of the Alzheimer type (PDAT) in the Northern Health Region (estimated population aged 45-64, 655,800) were ascertained for the years 1979-86 from in-patient ICD-9 codes and other sources. An algorithm was applied to the casenote information to distinguish between Alzheimer-type an...

journal_title：Psychological medicine

authors： Newens AJ,Forster DP,Kay DW,Kirkup W,Bates D,Edwardson J

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...

journal_title：Psychological medicine

authors： Srinivasa Murthy R,Kishore Kumar KV,Chisholm D,Thomas T,Sekar K,Chandrashekari CR

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Prior research suggested that time splitting--suppressing the past and dissociating it from present and future--protected refugee mental health in the aftermath of catastrophe. The current study investigates temporal reintegration, defined as cognitive recapture of the past and reconnecting it with present a...

journal_title：Psychological medicine

authors： Beiser M,Wickrama KA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Interpersonal stress generation is an important maintaining factor in major depression; however, little is known about the psychological mechanisms that undermine interpersonal functioning. This study investigated the role of deficits in person perception to this regard. METHOD:Depressed patients (n = 20) a...

journal_title：Psychological medicine

authors： Boecking B,Barnhofer T

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Previous research suggests that genetic influences on disordered eating may be greater in pubertal than pre-pubertal girls. Although these findings are consistent with pubertal activation of genetic influences on disordered eating, earlier studies were unable to directly test this hypothesis. The purpose of ...

journal_title：Psychological medicine

authors： Klump KL,Perkins PS,Alexandra Burt S,McGue M,Iacono WG

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Moodscope is an entirely service-user-developed online mood-tracking and feedback tool with built-in social support, designed to stabilize and improve mood. Many free internet tools are available with no assessment of acceptability, validity or usefulness. This study provides an exemplar for future assessmen...

journal_title：Psychological medicine

authors： Drake G,Csipke E,Wykes T

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes. METHOD:Family practice attendees were recruited between April 2003 and February 2005 and followed over 24 months in the UK, Spain...

journal_title：Psychological medicine

authors： King M,Bottomley C,Bellón-Saameño JA,Torres-Gonzalez F,Švab I,Rifel J,Maaroos HI,Aluoja A,Geerlings MI,Xavier M,Carraça I,Vicente B,Saldivia S,Nazareth I

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:The phenotypic stability of avoidant personality disorder (AVPD) and obsessive-compulsive personality disorder (OCPD) has previously been found to be moderate. However, little is known about the longitudinal structure of genetic and environmental factors for these disorders separately and jointly, and to wha...

journal_title：Psychological medicine

authors： Gjerde LC,Czajkowski N,Røysamb E,Ystrom E,Tambs K,Aggen SH,Ørstavik RE,Kendler KS,Reichborn-Kjennerud T,Knudsen GP

更新日期：2015-12-01 00:00:00

abstract：:Couples in whom the main complaint was of a lack of female sexual response were treated using a practical counselling approach. A number of pre-treatment measures were studied to determine which factors were predictive of treatment outcome. While age and chronicity were not predictive, the quality of the general relat...

journal_title：Psychological medicine

authors： Whitehead A,Mathews A

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Assortative mating has been demonstrated in mental disorders but the extent of cohabitation between patients with clinically diagnosed psychiatric disease has been poorly explored. Method We conducted a register-based study of all Danes between 18 and 70 years of age in a 13-year observational period, linkin...

journal_title：Psychological medicine

authors： Thomsen AF,Olsbjerg M,Andersen PK,Kessing LV

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Patient satisfaction is a key indicator of inpatient care quality and is associated with clinical outcomes following admission. Different patient characteristics have been inconsistently linked with satisfaction. This study aims to overcome previous limitations by assessing which patient characteristics are ...

journal_title：Psychological medicine

authors： Bird V,Miglietta E,Giacco D,Bauer M,Greenberg L,Lorant V,Moskalewicz J,Nicaise P,Pfennig A,Ruggeri M,Welbel M,Priebe S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Childhood early life stress (ELS) increases risk of adulthood major depressive disorder (MDD) and is associated with altered brain structure and function. It is unclear whether specific ELSs affect depression risk, cognitive function and brain structure. METHOD:This cross-sectional study included 64 antidep...

journal_title：Psychological medicine

authors： Saleh A,Potter GG,McQuoid DR,Boyd B,Turner R,MacFall JR,Taylor WD

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Although hallucinations have been studied in terms of prevalence and its associations with psychopathology and functional impairment, very little is known about sensory modalities other than auditory (i.e. haptic, visual and olfactory), as well the incidence of hallucinations, factors predicting incidence an...

journal_title：Psychological medicine

authors： Moriyama TS,Drukker M,Guloksuz S,Ten Have M,de Graaf R,van Dorsselaer S,Gunther N,Bak M,van Os J

更新日期：2020-04-22 00:00:00

abstract：:The relationships among symptoms, cognitive functioning and social functioning were investigated in 60 patients with recent-onset schizophrenia. Positive symptoms were unrelated to cognitive measures. Disorganization and depressive symptoms were correlated significantly with Card Sorting performance. Furthermore, only...

journal_title：Psychological medicine

authors： Van der Does AJ,Dingemans PM,Linszen DH,Nugter MA,Scholte WF

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD), such that MDD has been associated with guilt-driven pathological hyper-altruism. However, the impact of such emotional impairments in MDD on different ...

journal_title：Psychological medicine

authors： Pulcu E,Thomas EJ,Trotter PD,McFarquhar M,Juhasz G,Sahakian BJ,Deakin JF,Anderson IM,Zahn R,Elliott R

更新日期：2015-04-01 00:00:00

abstract：:The blood counts of 80 patients with depression were examined (50 unipolar, 30 bipolar). Many had reduced numbers of circulating lymphocytes. This abnormality was more common in the unipolar group (52%) than in the bipolar group (27%). When those patients with an abnormal dexamethasone suppression test response in bot...

journal_title：Psychological medicine

authors： Murphy D,Gardner R,Greden JF,Carroll BJ

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Current mental health legislation in the UK makes provision for the use of certain treatments in severely ill patients who are unable, or unwilling, to give informed consent. Under the terms of this legislation, electroconvulsive therapy (ECT) may be used, usually to treat severely depressed patients. A numb...

journal_title：Psychological medicine

authors： Wheeldon TJ,Robertson C,Eagles JM,Reid IC

更新日期：1999-01-01 00:00:00

abstract：:Over 90% of the 1202 patients investigated in the 9 centres collaborating in the International Pilot Study of Schizophrenia were traced 2 years after the initial examination and on the average over 75% of them were re-examined, using standardized instruments and methods. Results indicate that patients diagnosed as sch...

journal_title：Psychological medicine

authors： Sartorius N,Jablensky A,Shapiro R

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Assaultive violence events are associated with increased risk for adverse psychiatric outcomes, including post-traumatic stress (PTS), depression, and generalized anxiety. Prior research has indicated that economic, legal, and social stressors that could follow assaultive events may explain the increased ris...

journal_title：Psychological medicine

authors： Lowe SR,Joshi S,Galea S,Aiello AE,Uddin M,Koenen KC,Cerdá M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Self-harm among young adults is a common and increasing phenomenon in many parts of the world. The long-term prognosis after self-harm at young age is inadequately known. We aimed to estimate the risk of mental illness and suicide in adult life after self-harm in young adulthood and to identify prognostic fa...

journal_title：Psychological medicine

authors： Beckman K,Mittendorfer-Rutz E,Lichtenstein P,Larsson H,Almqvist C,Runeson B,Dahlin M

更新日期：2016-12-01 00:00:00