Cognitive impairment in the euthymic phase of affective disorder.

Abstract:

BACKGROUND:A review of studies of cognition in the euthymic phase of unipolar and bipolar affective disorder reveals diverging results. METHODS:The study was designed as a controlled cohort study, with the Danish psychiatric case register of admissions used to identify patients and the Danish civil register to identify controls. Patients who were hospitalized between 19 and 25 years ago with an affective diagnosis and who at interviews fulfilled criteria for a primary affective unipolar or bipolar disorder, according to ICD-10, were compared with age- and gender-matched controls. Interviews and assessment of the cognitive function were made in the euthymic phase of the disorder. In all, 118 unipolar patients, 28 bipolar patients and 58 controls were included. Analyses were adjusted for differences in the level of education and for subclinical depressive and anxiety symptoms. RESULTS:Patients with recurrent episodes were significantly more impaired than patients with a single episode and more impaired than controls. Also, within patients the number of prior episodes seemed to be associated with cognitive outcome. There was no difference in the severity of the dysfunction between unipolar and bipolar patients. CONCLUSIONS:Cognitive impairment in out-patients with unipolar and bipolar disorder appears to be associated with the number of affective episodes.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Kessing LV

doi

10.1017/s0033291798006862

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

1027-38

issue

5

eissn

0033-2917

issn

1469-8978

journal_volume

28

pub_type

临床试验,杂志文章
  • Allusive thinking, the Word Halo and verbosity.

    abstract::The concept of allusive thinking is briefly reviewed and a Pavlovian model of thinking advanced. It is hypothesized that allusive, as compared with non-allusive thinkers, have a broader but less intense attention process associated with weaker inhibition. From this model it was predicted that on word tests which requi...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700004414

    authors: Armstrong MS,McConaghy N

    更新日期:1977-08-01 00:00:00

  • Cognitive function in unaffected twins discordant for affective disorder.

    abstract:BACKGROUND:Patients may present with cognitive impairment in the euthymic phase of affective disorder, but it is unclear whether the impairment is prevalent before onset of the illness. The aim of the present study was to examine the hypothesis that genetic liability to affective disorder is associated with cognitive i...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291706007896

    authors: Christensen MV,Kyvik KO,Kessing LV

    更新日期:2006-08-01 00:00:00

  • The associations of high levels of C-reactive protein with depression and myocardial infarction in 9258 women and men from the HUNT population study.

    abstract:BACKGROUND:Elevated levels of circulating C-reactive protein (CRP) have been associated with coronary heart disease and, in some studies, depression. Most studies have been of populations selected by age and/or gender. We investigate these associations with depression, myocardial infarction (MI), or both, in a large ge...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291710000887

    authors: Bjerkeset O,Romild U,Smith GD,Hveem K

    更新日期:2011-02-01 00:00:00

  • Comparison of alternative models for personality disorders, II: 6-, 8- and 10-year follow-up.

    abstract:BACKGROUND:Several conceptual models have been considered for the assessment of personality pathology in DSM-5. This study sought to extend our previous findings to compare the long-term predictive validity of three such models: the five-factor model (FFM), the schedule for nonadaptive and adaptive personality (SNAP), ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711002601

    authors: Morey LC,Hopwood CJ,Markowitz JC,Gunderson JG,Grilo CM,McGlashan TH,Shea MT,Yen S,Sanislow CA,Ansell EB,Skodol AE

    更新日期:2012-08-01 00:00:00

  • Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities.

    abstract:BACKGROUND:Previous research has found that depression is a major cause of memory complaints. However, there is evidence that memory complaints also weakly predict cognitive decline and dementia. The present study examined a range of possible determinants of memory complaints, covering psychiatric and personality facto...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704003162

    authors: Jorm AF,Butterworth P,Anstey KJ,Christensen H,Easteal S,Maller J,Mather KA,Turakulov RI,Wen W,Sachdev P

    更新日期:2004-11-01 00:00:00

  • Alexithymia and frontal-amygdala functional connectivity in North Korean refugees.

    abstract:BACKGROUND:Refugees commonly experience difficulties with emotional processing, such as alexithymia, due to stressful or traumatic experiences. However, the functional connectivity of the amygdala, which is central to emotional processing, has yet to be assessed in refugees. Thus, the present study investigated the res...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719000175

    authors: Kim N,Park I,Lee YJ,Jeon S,Kim S,Lee KH,Park J,Kim HK,Gwaq AR,Jun JY,Yoo SY,Lee SH,Kim SJ

    更新日期:2020-01-01 00:00:00

  • Magnetic resonance imaging volumetric measurements of the superior temporal gyrus, hippocampus, parahippocampal gyrus, frontal and temporal lobes in late paraphrenia.

    abstract::Quantified magnetic resonance measurements were made of superior temporal gyrus, parahippocampal gyrus, hippocampal, frontal and temporal lobe volumes and of the planar area of the thalamus and basal ganglia structures in 47 late paraphrenic patients and 33 healthy elderly controls. The late paraphrenics were divided ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700033419

    authors: Howard R,Mellers J,Petty R,Bonner D,Menon R,Almeida O,Graves M,Renshaw C,Levy R

    更新日期:1995-05-01 00:00:00

  • How abnormal is the desire for slimness? A survey of eating attitudes and behaviour among Chinese undergraduates in Hong Kong.

    abstract::Using the 40-item Eating Attitudes Test and other self-report questions, a two-stage screening survey of 1020 (F 646, M 374) Chinese bilingual university students in Hong Kong showed that although female students were 'underweight' by Western standard, the majority of them and nearly all female students above a body m...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700028531

    authors: Lee S

    更新日期:1993-05-01 00:00:00

  • Sibling pairs with affective disorders: resemblance of demographic and clinical features.

    abstract:BACKGROUND:As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD:Data on age at onset, g...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291701004986

    authors: O'Mahony E,Corvin A,O'Connell R,Comerford C,Larsen B,Jones R,McCandless F,Kirov G,Cardno AG,Craddock N,Gill M

    更新日期:2002-01-01 00:00:00

  • Lithium and erythrocyte membrane cation carrier studies in normal and manic depressive subjects.

    abstract::Changes in the erythrocyte membrane cation carrier following lithium ingestion in normal human subjects were studied; ouabain sensitive potassium influx fell significantly during the lithium treated phase. Lithium was fed to rats and no change in erythrocyte Na-K ATPase was shown. These findings contrast with studies ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700029305

    authors: Naylor GJ,Smith A,Boardman LJ,Dick DA,Dick EG,Dick P

    更新日期:1977-05-01 00:00:00

  • The effect of COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes on hippocampal and lateral ventricular volume in psychosis.

    abstract:BACKGROUND:Morphometric endophenotypes which have been proposed for psychotic disorders include lateral ventricular enlargement and hippocampal volume reductions. Genetic epidemiological studies support an overlap between schizophrenia and bipolar disorder, and COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes have been implica...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709990316

    authors: Dutt A,McDonald C,Dempster E,Prata D,Shaikh M,Williams I,Schulze K,Marshall N,Walshe M,Allin M,Collier D,Murray R,Bramon E

    更新日期:2009-11-01 00:00:00

  • Depressive symptom clusters are differentially associated with atherosclerotic disease.

    abstract:BACKGROUND:Depression increases the risk of subsequent vascular events in both cardiac and non-cardiac patients. Atherosclerosis, the underlying process leading to vascular events, has been associated with depression. This association, however, may be confounded by the somatic-affective symptoms being a consequence of ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291710002151

    authors: Bus BA,Marijnissen RM,Holewijn S,Franke B,Purandare N,de Graaf J,den Heijer M,Buitelaar JK,Voshaar RC

    更新日期:2011-07-01 00:00:00

  • Classification of severe school attendance problems.

    abstract::Sixty-four children taken to court for failure to attend school were reliably classified into 4 groups, according to whether they exhibited the features of 'school refusal' and/or 'truancy'. About a fifth of them were found to exhibit 'school refusal'; a third showed 'truancy'; less than a sixth exhibited both 'school...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700021024

    authors: Berg I,Casswell G,Goodwin A,Hullin R,McGuire R,Tagg G

    更新日期:1985-02-01 00:00:00

  • The neuroscience of free will: implications for psychiatry.

    abstract::Belief in free will has been a mainstay in philosophy throughout history, grounded in large part in our intuitive sense that we consciously control our actions and could have done otherwise. However, psychology and psychiatry have long sought to uncover mechanistic explanations for human behavior that challenge the no...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291713002985

    authors: Pierre JM

    更新日期:2014-09-01 00:00:00

  • Pituitary volume and clinical trajectory in young relatives at risk for schizophrenia.

    abstract:BACKGROUND:Stress and vulnerability likely interact to play a major role in psychosis. While much has been written about the neural diathesis-stress model in psychosis and its clinical risk states, little is known about HPA axis biomarkers in non-help-seeking individuals at familial high risk (FHR). We sought to prospe...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S003329171500077X

    authors: Shah JL,Tandon N,Howard ER,Mermon D,Miewald JM,Montrose DM,Keshavan MS

    更新日期:2015-10-01 00:00:00

  • Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder.

    abstract:BACKGROUND:In the conditioned fear paradigm, repeated pairing of an aversive unconditioned stimulus (US) (e.g. electric shock) with a neutral conditioned stimulus (CS) (e.g. bright light) results in a conditioned fear response to the light alone. Animal studies have shown that the amygdala plays a critical role in acqu...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704003290

    authors: Bremner JD,Vermetten E,Schmahl C,Vaccarino V,Vythilingam M,Afzal N,Grillon C,Charney DS

    更新日期:2005-06-01 00:00:00

  • A modified video camera for measuring body image distortion: technical description and reliability.

    abstract::Previously employed techniques for the measurement of body image are briefly described, with a short consideration of methodological or procedural limitations associated with each technique. A new procedure is described which employs a simple modification to a standard video camera to produce an image which appears fr...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700003652

    authors: Freeman RJ,Thomas CD,Solyom L,Hunter MA

    更新日期:1984-05-01 00:00:00

  • Personality characteristics of the parents of autistic individuals.

    abstract::Personality characteristics of 87 parents of autistic probands and 38 parents of Down's syndrome probands were examined using a standardized personality interview. Using best-estimate ratings derived from subject and informant interviews, parents of autistic individuals were rated significantly higher than controls on...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700027938

    authors: Piven J,Wzorek M,Landa R,Lainhart J,Bolton P,Chase GA,Folstein S

    更新日期:1994-08-01 00:00:00

  • Impulsivity and neural correlates of response inhibition in schizophrenia.

    abstract:BACKGROUND:The clinical picture of schizophrenia is frequently worsened by manifestations of impulsivity. However, the neural correlates of impulsivity in this disorder are poorly known. Although impulsivity has been related to disturbances of the neural processes underlying response inhibition, no studies have yet exa...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291710000796

    authors: Kaladjian A,Jeanningros R,Azorin JM,Anton JL,Mazzola-Pomietto P

    更新日期:2011-02-01 00:00:00

  • Depression and memory function - evidence from cross-lagged panel models with unit fixed effects in ELSA and HRS.

    abstract:BACKGROUND:Individuals with depression are often found to perform worse on cognitive tests and to have an increased risk of dementia. The causes and the direction of these associations are however not well understood. We looked at two specific hypotheses, the aetiological risk factor hypothesis and the reverse causalit...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720003037

    authors: Jindra C,Li C,Tsang RSM,Bauermeister S,Gallacher J

    更新日期:2020-09-11 00:00:00

  • The effects of unemployment on psychiatric illness during young adulthood.

    abstract:BACKGROUND:The aims of this study were to examine the associations between exposure to unemployment following school leaving and rates of psychiatric disorder using data gathered on a birth cohort of New Zealand young people studied up to the age of 18. METHODS:At age 18 cohort members were assessed on: (a) duration o...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291796004412

    authors: Fergusson DM,Horwood LJ,Lynskey MT

    更新日期:1997-03-01 00:00:00

  • Type A and type B behaviour patterns, task type and sensitivity to noise.

    abstract::The present study examined sensitivity to noise in subjects with Type A and Type B behaviour patterns as a function of the type of task being performed. Twenty Type A and 20 Type B subjects, selected by means of Bortner's scale (French version), were exposed to steadily increasing noise levels (68-110 dBA) while perfo...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700015245

    authors: Moch A

    更新日期:1984-08-01 00:00:00

  • Co-morbidity and disorder-related distress and impairment in purging disorder.

    abstract:BACKGROUND:Recent studies suggest that purging disorder (PD) may be a common eating disorder that is associated with clinically significant levels of distress and high levels of psychiatric co-morbidity. However, no study has established evidence of disorder-related impairment or whether distress is specifically relate...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291707001390

    authors: Keel PK,Wolfe BE,Gravener JA,Jimerson DC

    更新日期:2008-10-01 00:00:00

  • Outcome of women admitted to hospital for depressive illness: factors in the prognosis of severe depression.

    abstract:BACKGROUND:A previous study of women 9 months after discharge from in-patient treatment for depression found that low self-esteem as measured by a self-report questionnaire at admission was associated with a worse prognosis. This study investigates the womens' outcome more than 4 years after discharge and the continued...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291799002986

    authors: Sherrington JM,Hawton K,Fagg J,Andrew B,Smith D

    更新日期:2001-01-01 00:00:00

  • Childhood adversities and risk for suicidal ideation and attempts: a longitudinal population-based study.

    abstract:BACKGROUND:Developmental adversities may be risk factors for adult suicidal behavior, but this relationship has rarely been studied prospectively. The present study examined the association between childhood adversities and new onset suicidal ideation and attempts in an adult population-based sample. METHOD:The study ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291706008646

    authors: Enns MW,Cox BJ,Afifi TO,De Graaf R,Ten Have M,Sareen J

    更新日期:2006-12-01 00:00:00

  • Psychiatric aspects of railway fatalities.

    abstract::National statistics for railway fatalities in England and Wales show a reduction of train crashes and a fluctuating level of deaths, of which an increasing proportion is from suicide. A closer examination of a two-year sample from the South of England revealed a large proportion of probable suicides and a small propor...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700031469

    authors: Symonds RL

    更新日期:1985-08-01 00:00:00

  • Influence of the noradrenergic system on the formation of intrusive memories in women: an experimental approach with a trauma film paradigm.

    abstract:BACKGROUND:Intrusive memories of traumatic events are a core feature of post-traumatic stress disorder but little is known about the neurobiological formation of intrusions. The aim of this study was to determine whether the activity of the noradrenergic system during an intrusion-inducing stressor would influence subs...

    journal_title:Psychological medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0033291716001379

    authors: Rombold F,Wingenfeld K,Renneberg B,Hellmann-Regen J,Otte C,Roepke S

    更新日期:2016-09-01 00:00:00

  • Psychiatric symptoms during l-dopa therapy for Parkinson's disease and their relationship to physical disability.

    abstract::Fifty patients attending a neurological outpatient clinic for Parkinson's disease were assessed by standardized methods for both physical and psychiatric symptoms. The patients then received treatment with L-dopa with carbidopa or anticholinergic drugs and/or amantadine. During the following six-month period the subje...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0033291700007467

    authors: Mindham RH,Marsden CD,Parkes JD

    更新日期:1976-02-01 00:00:00

  • Kraepelin revisited: a reassessment and statistical analysis of dementia praecox and manic-depressive insanity in 1908.

    abstract::A meta-analysis was carried out on 53 cases of dementia praecox (DP) and 134 cases of manic-depressive insanity (MDI) originally diagnosed by Kraepelin or his collaborators in Munich in 1908. The original case material was coded in terms of Present State Examination syndromes and analysed statistically for internal co...

    journal_title:Psychological medicine

    pub_type: 传,历史文章,杂志文章,meta分析

    doi:10.1017/s0033291700026337

    authors: Jablensky A,Hugler H,Von Cranach M,Kalinov K

    更新日期:1993-11-01 00:00:00

  • Risk factors for major depression during midlife among a community sample of women with and without prior major depression: are they the same or different?

    abstract:BACKGROUND:Women's vulnerability for a first lifetime-onset of major depressive disorder (MDD) during midlife is substantial. It is unclear whether risk factors differ for first lifetime-onset and recurrent MDD. Identifying these risk factors can provide more focused depression screening and earlier intervention. This ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1017/S0033291714002773

    authors: Bromberger JT,Schott L,Kravitz HM,Joffe H

    更新日期:2015-06-01 00:00:00