Pituitary volume and clinical trajectory in young relatives at risk for schizophrenia.

abstract：BACKGROUND:Puberty moderates genetic influences on disordered eating attitudes and behaviors, with little genetic influence before puberty but large (50%) genetic effects during and after puberty. To date, however, nothing is known about the mechanisms that underlie these effects. Estradiol is a particularly promising ...

journal_title：Psychological medicine

authors： Klump KL,Keel PK,Sisk C,Burt SA

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Breathlessness in asthma often cannot be explained with objective variables indicating airways obstruction. The hypothesis that unrealistic breathlessness results from false interpretation of sensations was tested. METHODS:Sixty-four children and adolescents with asthma, aged 9-18 years, were randomly assig...

journal_title：Psychological medicine

authors： Rietveld S,Everaerd W,Vanbeest I

更新日期：1999-01-01 00:00:00

abstract：:Previous studies have reported an increase in depression among recent birth cohorts. Concurrent with the increase in rates of depression, there have been increases in rates of drug and alcohol abuse and dependence. This study sought to determine if the recent increase in rates of depression could be attributed to co-m...

journal_title：Psychological medicine

authors： Klerman GL,Leon AC,Wickramaratne P,Warshaw MG,Mueller TI,Weissman MM,Akiskal H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Agitated patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians differ in opinion and practice. In Lebanon, the use of the triple therapy haloperidol plus promethazine plus chlorpromazine (HPC) is frequently used but no studies involving t...

journal_title：Psychological medicine

authors： Dib JE,Yaacoub HE,Ikdais WH,Atallah E,Merheb TJ,Ajaltouni J,Akkari M,Mourad M,Nasr ME,Hachem D,Kazour F,Tahan F,Haddad G,Azar J,Zoghbi M,Haddad C,Hallit S,Adams CE

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:The Psychiatric Genomics Consortium (PGC) has made major advances in the molecular etiology of MDD, confirming that MDD is highly polygenic. Pathway enrichment results from PGC meta-analyses can also be used to help inform molecular drug targets. Prior to any knowledge of molecular biomarkers for MDD, drugs ...

journal_title：Psychological medicine

authors： Docherty AR,Moscati A,Bigdeli TB,Edwards AC,Peterson RE,Adkins DE,Anderson JS,Flint J,Kendler KS,Bacanu SA

更新日期：2020-04-01 00:00:00

abstract：:This paper describes a modified version of the MRC Needs for Care Schedule (the Cardinal Needs Schedule), for measuring needs for psychiatric and social care amongst patients with severe psychiatric disorders. The modified schedule has three new features: (i) it is quick and easy to use; (ii) it takes systematic accou...

journal_title：Psychological medicine

authors： Marshall M,Hogg LI,Gath DH,Lockwood A

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Although positive effects of physical activity on mental health indicators have been reported, the relationship between physical activity and the development of specific mental disorders is unclear. METHOD:A cross-sectional (12-month) and prospective-longitudinal epidemiological study over 4 years in a comm...

journal_title：Psychological medicine

authors： Ströhle A,Höfler M,Pfister H,Müller AG,Hoyer J,Wittchen HU,Lieb R

更新日期：2007-11-01 00:00:00

abstract：:One hundred and eighteen subjects with an admission diagnosis of schizophrenia were reassessed after 12 months to establish whether hospital readmission had occurred. All subjects were rated at baseline and after 12 months on the Life Skills Profile (LSP), a 39-item measure of disability, with scores demonstrating mod...

journal_title：Psychological medicine

authors： Parker G,Hadzi-Pavlovic D

更新日期：1995-01-01 00:00:00

abstract：INTRODUCTION:Cognitive therapy (CT) for bipolar disorder emphasizes the monitoring and regulation of mood, thoughts and behaviour. The Sense of Hyper-Positive Self Scale (SHPSS) measures the extent to which bipolar patients value themselves and perceive themselves to possess personal attributes (e.g. dynamism, persuasi...

journal_title：Psychological medicine

authors： Lam D,Wright K,Sham P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Dissociative reactions in post-traumatic stress disorder (PTSD) have been regarded as strategic responses that limit arousal. Neuroimaging studies suggest distinct prefrontal responses in individuals displaying dissociative and hyperarousal responses to threat in PTSD. Increased prefrontal activity may refle...

journal_title：Psychological medicine

authors： Felmingham K,Kemp AH,Williams L,Falconer E,Olivieri G,Peduto A,Bryant R

更新日期：2008-12-01 00:00:00

abstract：:Because of the potential importance of prolonged action neuroleptics for the delivery of care to schizophrenic patients, and because of the availability of new, extensive data from clinical trials on the utility of these drugs, a workshop conference was convened by the United States National Institute of Mental Health...

journal_title：Psychological medicine

authors： Levine J,Schooler NR,Cassano GB

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD), such that MDD has been associated with guilt-driven pathological hyper-altruism. However, the impact of such emotional impairments in MDD on different ...

journal_title：Psychological medicine

authors： Pulcu E,Thomas EJ,Trotter PD,McFarquhar M,Juhasz G,Sahakian BJ,Deakin JF,Anderson IM,Zahn R,Elliott R

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed. METHOD:Antecedent, concurrent and predictive markers of construct validity were examined for three models of PDs: the Five-Factor Model (FFM), the...

journal_title：Psychological medicine

authors： Morey LC,Hopwood CJ,Gunderson JG,Skodol AE,Shea MT,Yen S,Stout RL,Zanarini MC,Grilo CM,Sanislow CA,McGlashan TH

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:To date, there has been no large-scale survey of geriatric depression (GD) involving both rural and urban areas in China using standardized assessment tools and diagnostic criteria. This study aimed to determine the 12-month and lifetime prevalence rates of GD and sociodemographic correlates in urban and rur...

journal_title：Psychological medicine

authors： Ma X,Xiang YT,Li SR,Xiang YQ,Guo HL,Hou YZ,Cai ZJ,Li ZB,Li ZJ,Tao YF,Dang WM,Wu XM,Deng J,Ungvari GS,Chiu HF

更新日期：2008-12-01 00:00:00

abstract：:Couples in whom the main complaint was of a lack of female sexual response were treated using a practical counselling approach. A number of pre-treatment measures were studied to determine which factors were predictive of treatment outcome. While age and chronicity were not predictive, the quality of the general relat...

journal_title：Psychological medicine

authors： Whitehead A,Mathews A

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes. METHOD:Family practice attendees were recruited between April 2003 and February 2005 and followed over 24 months in the UK, Spain...

journal_title：Psychological medicine

authors： King M,Bottomley C,Bellón-Saameño JA,Torres-Gonzalez F,Švab I,Rifel J,Maaroos HI,Aluoja A,Geerlings MI,Xavier M,Carraça I,Vicente B,Saldivia S,Nazareth I

更新日期：2011-08-01 00:00:00

abstract：:The notion that psychotic symptoms lie on a continuum with normality has become an accepted dogma. It is supported by several lines of empirical evidence, fits in with the orientation of modern services and has a 'moral' appeal. However, there is confusion as to the nature of the continuum or continua under discussion...

journal_title：Psychological medicine

authors： David AS

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Childhood abuse is a risk factor for poorer illness course in bipolar disorder, but the reasons why are unclear. Trait-like features such as affective instability and impulsivity could be part of the explanation. We aimed to examine whether childhood abuse was associated with clinical features of bipolar dis...

journal_title：Psychological medicine

authors： Marwaha S,Briley PM,Perry A,Rankin P,DiFlorio A,Craddock N,Jones I,Broome M,Gordon-Smith K,Jones L

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:This study integrated an experimental medicine approach and a randomized cross-over clinical trial design following CONSORT recommendations to evaluate a cognitive training (CT) intervention for attention deficit hyperactivity disorder (ADHD). The experimental medicine approach was adopted because of documen...

journal_title：Psychological medicine

authors： Wexler BE,Vitulano LA,Moore C,Katsovich L,Smith SD,Rush C,Grantz H,Dong J,Leckman JF

更新日期：2020-02-24 00:00:00

abstract：BACKGROUND:The objective was to describe patients presenting themselves at emergency-care settings following a suicide attempt in eight culturally different sites [Campinas (Brazil), Chennai (India), Colombo (Sri Lanka), Durban (South Africa), Hanoi (Viet Nam), Karaj (Iran), Tallinn (Estonia), and Yuncheng, (China)]. ...

journal_title：Psychological medicine

authors： Fleischmann A,Bertolote JM,De Leo D,Botega N,Phillips M,Sisask M,Vijayakumar L,Malakouti K,Schlebusch L,De Silva D,Nguyen VT,Wasserman D

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Discontinuation of antipsychotics predisposes patients with remitted/stable first-episode psychosis (FEP) to a higher risk of relapse, but it remains unclear how long discontinuation increases the relapse rate in these patients compared with maintenance. METHODS:This meta-analysis of randomized controlled t...

journal_title：Psychological medicine

authors： Kishi T,Ikuta T,Matsui Y,Inada K,Matsuda Y,Mishima K,Iwata N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Studies investigating early developmental factors in relation to psychopathology have mainly focused on schizophrenia. The personality dimension of neuroticism seems to be a general risk factor for psychopathology, but evidence on associations between early developmental precursors and personality traits is ...

journal_title：Psychological medicine

authors： Flensborg-Madsen T,Sørensen HJ,Revsbech R,Mortensen EL

更新日期：2013-06-01 00:00:00

abstract：:Difficulties in set-shifting are commonly reported in both autism spectrum disorder (ASD) and anorexia nervosa (AN) populations. Despite this, it is not known whether this cognitive profile persists across different ages, or whether the profiles seen in ASD and AN are comparable. This systematic review and meta-analys...

journal_title：Psychological medicine

authors： Westwood H,Stahl D,Mandy W,Tchanturia K

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Studies have suggested that patients with schizophrenia are impaired at recognizing emotions. Recently, it has been shown that the neuropeptide oxytocin can have beneficial effects on social behaviors. METHOD:To examine emotion recognition deficits in patients and see whether oxytocin could improve these de...

journal_title：Psychological medicine

authors： Averbeck BB,Bobin T,Evans S,Shergill SS

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:There has been much recent excitement about the possibility that some cases of psychosis may be wholly due to brain-reactive antibodies, with antibodies to N-methyl-D-aspartate receptor (NMDAR) and the voltage-gated potassium channel (VGKC)-complex reported in a few patients with first-episode psychosis (FEP...

journal_title：Psychological medicine

authors： Gaughran F,Lally J,Beck K,McCormack R,Gardner-Sood P,Coutinho E,Jacobson L,Lang B,Sainz-Fuertes R,Papanastasiou E,Di Forti M,Nicholson T,Vincent A,Murray RM

更新日期：2018-06-01 00:00:00

abstract：:Hypothalamic-pituitary-adrenal axis function was investigated in 72 patients with primary depression. Forty-four per cent of the patients demonstrated abnormal suppression of their cortisol levels after a 1 mg overnight dexamethasone suppression test. Patients with abnormal suppression ('non-suppressors') were not cle...

journal_title：Psychological medicine

authors： Calloway SP,Dolan RJ,Fonagy P,De Souza VF,Wakeling A

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Although many case-control studies have replicated an association between dysfunctional parenting and a lifetime diagnosis of depression, few epidemiological studies have explored the association. In addition, little is known about the association in non-western countries. METHODS:Using logistic regression ...

journal_title：Psychological medicine

authors： Sato T,Sakado K,Uehara T,Narita T,Hirano S,Nishioka K,Kasahara Y

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Cognitive theory points to the importance of negative self-schemas in the onset and maintenance of depression and anxiety disorders. Hereby, it is important to distinguish between automatic and explicit self-schemas, reflecting different cognitive-motivational systems. This study tested whether patients with...

journal_title：Psychological medicine

authors： Glashouwer KA,de Jong PJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Cognitive models of obsessive-compulsive disorder (OCD) posit dysfunctional appraisal of disorder-relevant stimuli in patients, suggesting disturbances in the processes relying on amygdala-prefrontal connectivity. Recent neuroanatomical models add to the traditional view of dysfunction in corticostriatal cir...

journal_title：Psychological medicine

authors： Paul S,Beucke JC,Kaufmann C,Mersov A,Heinzel S,Kathmann N,Simon D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:In people with bulimic eating disorders, exposure to high-calorie foods can result in increases in food craving, raised subjective stress and salivary cortisol concentrations. This cue-induced food craving can be reduced by repetitive transcranial magnetic stimulation (rTMS). We investigated whether rTMS has...

journal_title：Psychological medicine

authors： Claudino AM,Van den Eynde F,Stahl D,Dew T,Andiappan M,Kalthoff J,Schmidt U,Campbell IC

更新日期：2011-06-01 00:00:00