Co-morbidity and disorder-related distress and impairment in purging disorder.

Abstract:

BACKGROUND:Recent studies suggest that purging disorder (PD) may be a common eating disorder that is associated with clinically significant levels of distress and high levels of psychiatric co-morbidity. However, no study has established evidence of disorder-related impairment or whether distress is specifically related to PD rather than to co-morbid disorders. METHOD:Three groups of normal-weight women [non-eating disorder controls (n=38), with PD (n=24), and with bulimia nervosa (BN)-purging subtype (n=57)] completed structured clinical interviews and self-report assessments. RESULTS:Both PD and BN were associated with significant co-morbidity and elevations on indicators of distress and impairment compared to controls. Compared to BN, PD was associated with lower rates of current and lifetime mood disorders but higher rates of current anxiety disorders. Elevated distress and impairment were maintained in PD and BN after controlling for Axis I and Axis II disorders. CONCLUSIONS:PD is associated with elevated distress and impairment and should be considered for inclusion as a provisional disorder in nosological schemes such as the Diagnostic and Statistical Manual to facilitate much-needed research on this clinically significant syndrome.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Keel PK,Wolfe BE,Gravener JA,Jimerson DC

doi

10.1017/S0033291707001390

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

1435-42

issue

10

eissn

0033-2917

issn

1469-8978

pii

S0033291707001390

journal_volume

38

pub_type

杂志文章
  • Manual-assisted cognitive-behaviour therapy (MACT): a randomized controlled trial of a brief intervention with bibliotherapy in the treatment of recurrent deliberate self-harm.

    abstract:BACKGROUND:The treatment of deliberate self-harm (parasuicide) remains limited in efficacy. Despite a range of psychosocial, educational and pharmacological interventions only one approach, dialectical behaviour therapy, a form of cognitive-behaviour therapy (CBT), has been shown to reduce repeat episodes, but this is ...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s003329179800765x

    authors: Evans K,Tyrer P,Catalan J,Schmidt U,Davidson K,Dent J,Tata P,Thornton S,Barber J,Thompson S

    更新日期:1999-01-01 00:00:00

  • Do cannabis and urbanicity co-participate in causing psychosis? Evidence from a 10-year follow-up cohort study.

    abstract:BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711000511

    authors: Kuepper R,van Os J,Lieb R,Wittchen HU,Henquet C

    更新日期:2011-10-01 00:00:00

  • Cognitive deficits in unipolar old-age depression: a population-based study.

    abstract:BACKGROUND:There is substantial variability in the degree of cognitive impairment among older depressed persons. Inconsistencies in previous findings may be due to differences in clinical and demographic characteristics across study samples. We assessed the influence of unipolar depression and severity of depression on...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291713001736

    authors: Pantzar A,Laukka EJ,Atti AR,Fastbom J,Fratiglioni L,Bäckman L

    更新日期:2014-04-01 00:00:00

  • Increased neural response to fear in patients recovered from depression: a 3T functional magnetic resonance imaging study.

    abstract:BACKGROUND:Previous imaging studies have revealed that acute major depression is characterized by altered neural responses to negative emotional stimuli. Typically, responses in limbic regions such as the amygdala are increased while activity in cortical regulatory regions such as the dorsolateral prefrontal cortex (DL...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709990596

    authors: Norbury R,Selvaraj S,Taylor MJ,Harmer C,Cowen PJ

    更新日期:2010-03-01 00:00:00

  • Genetic and environmental contributions to diagnostic fluctuation in anorexia nervosa and bulimia nervosa.

    abstract:BACKGROUND:Anorexia nervosa and bulimia nervosa are two severe eating disorders associated with high premature mortality, suicidal risk and serious medical complications. Transition between anorexia nervosa and bulimia nervosa over the illness course and familial co-aggregation of the two eating disorders imply aetiolo...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719002976

    authors: Yao S,Larsson H,Norring C,Birgegård A,Lichtenstein P,DʼOnofrio BM,Almqvist C,Thornton LM,Bulik CM,Kuja-Halkola R

    更新日期:2021-01-01 00:00:00

  • The structure of depression found in the general population.

    abstract::Principal component analysis was applied to data relating to depressive experiences collected from a general population sample. The structure of depression found in the general population showed strong similarities to that found in the psychiatric population. There were, however, important differences. Four substantia...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700047346

    authors: Cooke DJ

    更新日期:1980-08-01 00:00:00

  • Suicide in England and Wales: an analysis of 100 years, 1876-1975.

    abstract::The variations in suicide mortality in England and Wales over a 100-year period (1876-1975) are explained by the development of a descriptive model. The model used in a stepwise linear regression using 5 variables including toxic gas production. The variables give a good description of the observed changes in suicide ...

    journal_title:Psychological medicine

    pub_type: 历史文章,杂志文章

    doi:10.1017/s003329170005217x

    authors: Low AA,Farmer RD,Jones DR,Rohde JR

    更新日期:1981-05-01 00:00:00

  • Longitudinal changes in mental health and the COVID-19 pandemic: evidence from the UK Household Longitudinal Study.

    abstract:BACKGROUND:The COVID-19 pandemic has had a range of negative social and economic effects that may contribute to a rise in mental health problems. In this observational population-based study, we examined longitudinal changes in the prevalence of mental health problems from before to during the COVID-19 crisis and ident...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720004432

    authors: Daly M,Sutin AR,Robinson E

    更新日期:2020-11-13 00:00:00

  • Philippe Pinel and the foundations of modern psychiatric nosology.

    abstract::Philippe Pinel (1745-1826) played a major role in the foundation of modern psychiatric nosology. Much of his contribution, historically contextualized within the enlightenment generally and post-Revolutionary France more specifically, can be summarized through five themes in his background, education and writings. Fir...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720004183

    authors: Kendler KS

    更新日期:2020-12-01 00:00:00

  • An analysis of suicide and undetermined deaths in 17 predominantly Islamic countries contrasted with the UK.

    abstract:BACKGROUND:Suicide is expressly condemned in the Qu'ran, and traditionally few Islamic countries have reported suicide. Undetermined deaths are classified by the World Health Organization (WHO) as Other Violent Deaths (OVD) in ICD-9, or Other External Causes (OEC) in ICD-10. It has been suggested that to avoid under-re...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291706009159

    authors: Pritchard C,Amanullah S

    更新日期:2007-03-01 00:00:00

  • Major depressive episode among young adults: CIDI-SF versus SCAN consensus diagnoses.

    abstract:BACKGROUND:We aimed to evaluate the diagnostic accuracy of a highly structured diagnostic interview in relation to a semi-structured diagnostic procedure. We compared the World Health Organization Composite International Diagnostic Interview Short Form (CIDI-SF) in diagnosing major depressive episode (MDE) to consensus...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291702005810

    authors: Aalto-Setälä T,Haarasilta L,Marttunen M,Tuulio-Henriksson A,Poikolainen K,Aro H,Lönnqvist J

    更新日期:2002-10-01 00:00:00

  • Motivational interviewing to enhance adolescent mental health treatment engagement: a randomized clinical trial.

    abstract:BACKGROUND:The prevalence of anxiety and mood disorders in adolescents is a growing public health concern worldwide. Given the high rates of drop-out and limited resources available in psychiatric settings, the importance of engaging adolescents in evidence-based treatments cannot be understated. The aim of the study w...

    journal_title:Psychological medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0033291716000568

    authors: Dean S,Britt E,Bell E,Stanley J,Collings S

    更新日期:2016-07-01 00:00:00

  • Hedonic tone is associated with left supero-lateral medial forebrain bundle microstructure.

    abstract:BACKGROUND:The medial forebrain bundle (MFB) is an important pathway of the reward system. Two branches have been described using diffusion magnetic resonance imaging (MRI)-based tractography: the infero-medial MFB (imMFB) and the supero-lateral MFB (slMFB). Previous studies point to white-matter microstructural altera...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714001949

    authors: Bracht T,Doidge AN,Keedwell PA,Jones DK

    更新日期:2015-03-01 00:00:00

  • Visual attention in adults with attention-deficit/hyperactivity disorder before and after stimulant treatment.

    abstract:BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder which frequently persists into adulthood. The primary goal of the current study was to (a) investigate attentional functions of stimulant medication-naïve adults with ADHD, and (b) investigate the effects of 6 weeks of methylphe...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291718003628

    authors: Low AM,Vangkilde S,le Sommer J,Fagerlund B,Glenthøj B,Jepsen JRM,Bundesen C,Petersen A,Habekost T

    更新日期:2019-11-01 00:00:00

  • Major depression impairs incentive processing: evidence from the heart and the face.

    abstract:BACKGROUND:The present study tested the hypothesis of a differential pattern of reward and punishment responsiveness in depression measuring effort mobilization during anticipation and facial expressions during consumption. METHODS:Twenty patients with major depressive disorder (MDD) and 20 control participants worked...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291718001526

    authors: Franzen J,Brinkmann K,Gendolla GHE,Sentissi O

    更新日期:2019-04-01 00:00:00

  • Prevalence and sociodemographic correlates of depression in an elderly population living with family members in Beijing, China.

    abstract:BACKGROUND:To date, there has been no large-scale survey of geriatric depression (GD) involving both rural and urban areas in China using standardized assessment tools and diagnostic criteria. This study aimed to determine the 12-month and lifetime prevalence rates of GD and sociodemographic correlates in urban and rur...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291708003164

    authors: Ma X,Xiang YT,Li SR,Xiang YQ,Guo HL,Hou YZ,Cai ZJ,Li ZB,Li ZJ,Tao YF,Dang WM,Wu XM,Deng J,Ungvari GS,Chiu HF

    更新日期:2008-12-01 00:00:00

  • The social causation of depression: a critique of the work of Brown and his colleagues.

    abstract::Brown and his colleagues have presented evidence for the social origins of depression from results of 2 community surveys in Camberwell. This paper examines critically their methodology, conceptualization of variables, mode of argument and statistical techniques. Log-linear analysis of their published data fails to su...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s003329170001878x

    authors: Tennant C,Bebbington P

    更新日期:1978-11-01 00:00:00

  • Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy.

    abstract:BACKGROUND:Major depressive disorder during pregnancy associates with potentially detrimental consequences for mother and child. The current study examined peripheral blood gene expression as a potential biomarker for prenatal depressive symptoms. METHOD:Maternal RNA from whole blood, plasma and the Beck Depression In...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291711002121

    authors: Katz ER,Stowe ZN,Newport DJ,Kelley ME,Pace TW,Cubells JF,Binder EB

    更新日期:2012-05-01 00:00:00

  • What is the impact of genome-wide supported risk variants for schizophrenia and bipolar disorder on brain structure and function? A systematic review.

    abstract::The powerful genome-wide association studies (GWAS) revealed common mutations that increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority were not known to be functional or associated with these illnesses. To help fill this gap, their impact on human brain structure and functio...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291715000537

    authors: Gurung R,Prata DP

    更新日期:2015-01-01 00:00:00

  • Psychiatric morbidity in patients with Parkinson's disease.

    abstract::Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, rev...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700013246

    authors: Brown RG,MacCarthy B

    更新日期:1990-02-01 00:00:00

  • Item response modeling of DSM-IV mania symptoms in two representative US epidemiological samples.

    abstract:BACKGROUND:There is considerable debate surrounding the effective measurement of DSM-IV symptoms used to assess manic disorders in epidemiological samples. METHOD:Using two nationally representative datasets, the National Epidemiological Survey of Alcohol and Related Conditions (NESARC, n=43,093 at wave 1, n=34,653 at...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709992005

    authors: Agrawal A,Nurnberger JI Jr,Lynskey MT

    更新日期:2010-09-01 00:00:00

  • Cost-effectiveness of cognitive behavioural therapy, graded exercise and usual care for patients with chronic fatigue in primary care.

    abstract:BACKGROUND:Chronic fatigue is a common condition, frequently presenting in primary care. The aim of this study was to compare the cost-effectiveness of cognitive behavioural therapy (CBT) and graded exercise therapy (GET), and to compare therapy with usual care plus a self-help booklet (BUC). METHOD:Patients drawn fro...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0033291704001928

    authors: McCrone P,Ridsdale L,Darbishire L,Seed P

    更新日期:2004-08-01 00:00:00

  • Reduction in the occurrence of distressing involuntary memories following propranolol or hydrocortisone in healthy women.

    abstract:BACKGROUND:Pharmacological treatments targeting the neuroendocrine stress response may hold special promise in secondary prevention of posttraumatic stress disorder (PTSD). However, findings from clinical trials have been inconsistent and the efficacy of specific drugs, their temporal window of efficacy, effective dose...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291719001028

    authors: Kamboj SK,Gong AT,Sim Z,Rashid AA,Baba A,Iskandar G,Das RK,Curran HV

    更新日期:2020-05-01 00:00:00

  • Reward learning deficits in Parkinson's disease depend on depression.

    abstract:BACKGROUND:Depression is one of the most common and debilitating non-motor symptoms of Parkinson's disease (PD). The neurocognitive mechanisms underlying depression in PD are unclear and treatment is often suboptimal. METHODS:We investigated the role of striatal dopamine in reversal learning from reward and punishment...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717000769

    authors: Timmer MHM,Sescousse G,van der Schaaf ME,Esselink RAJ,Cools R

    更新日期:2017-10-01 00:00:00

  • Effect of neighbourhood deprivation and social cohesion on mental health inequality: a multilevel population-based longitudinal study.

    abstract:BACKGROUND:The common mental disorders (CMDs) of anxiety and depression are the most common form of poor mental health in the general population. Evidence from the small number of previous cohort studies on the role of neighbourhood factors in mental health is inconclusive. We tested the hypothesis that high levels of ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291713003255

    authors: Fone D,White J,Farewell D,Kelly M,John G,Lloyd K,Williams G,Dunstan F

    更新日期:2014-08-01 00:00:00

  • Correlates of codisorders in homeless and never homeless indigent schizophrenic men.

    abstract::We recently completed a case-control study of 100 literally homeless and 100 never homeless indigent schizophrenic men in New York City, in which concurrent substance abuse and antisocial personality disorder were widespread. In this paper we probe the correlates of 'pure' schizophrenia (single disorder, N = 60), schi...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700027835

    authors: Caton CL,Shrout PE,Eagle PF,Opler LA,Felix A

    更新日期:1994-08-01 00:00:00

  • Elasticity and confabulation in schizophrenic delusions.

    abstract:BACKGROUND:This experiment examines two aspects of delusional cognition that have been reported clinically but not investigated empirically. These are the incorporation of potentially conflicting information into the recall of delusion-related scripts and the type and amount of material produced additional to that pres...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s003329170200538x

    authors: Simpson J,Done DJ

    更新日期:2002-04-01 00:00:00

  • Increasing right hand dominance with age on a motor skill task.

    abstract::A standardized pegboard task was used to investigate changes in manipulative skill as a function of age in 119 right-handed subjects. The typical pattern of cognitive impairment in old age indicates a relative preservation of functions which depend on the integrity of the left hemisphere. In accord with these observat...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700005109

    authors: Weller MP,Latimer-Sayer DT

    更新日期:1985-11-01 00:00:00

  • Bulimia nervosa: treatment and short-term outcome.

    abstract::Fifty-six bulimia nervosa patients were treated by means of a behavioural approach and followed for at least one year after completion or dropping out of treatment. Outcome was encouraging in about half of the patients and several psychiatric indicators, such as duration of illness and response to treatment, were iden...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700002543

    authors: Hsu LK,Holder D

    更新日期:1986-02-01 00:00:00

  • Behavioural and neurocognitive responses to sad facial affect are attenuated in patients with mania.

    abstract:BACKGROUND:The processing of facial emotion involves a distributed network of limbic and paralimbic brain structures. Many of these regions are also implicated in the pathophysiology of mood disorders. Behavioural data indicate that depressed subjects show a state-related positive recognition bias for faces displaying ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704002557

    authors: Lennox BR,Jacob R,Calder AJ,Lupson V,Bullmore ET

    更新日期:2004-07-01 00:00:00