The influence of prior expectations on facial expression discrimination in schizophrenia.

Abstract:

BACKGROUND:Belief inflexibility is a thinking style observed in patients with schizophrenia, in which patients tend to refute evidence that runs counter to their prior beliefs. This bias has been related to a dominance of prior expectations (prior beliefs) over incoming sensory evidence. In this study we investigated the reliance on prior expectations for the processing of emotional faces in schizophrenia. METHOD:Eighteen patients with schizophrenia and 18 healthy controls were presented with sequences of emotional (happy, fearful, angry or neutral) faces. Perceptual decisions were biased towards a particular expression by a specific instruction at the start of each sequence, referred to as the context in which stimuli occurred. Participants were required to judge the emotion on each face and the effect of the context on emotion discrimination was investigated. RESULTS:For threatening emotions (anger and fear), there was a performance cost for facial expressions that were incongruent with, and perceptually close to, the expression named in the instruction. For example, for angry faces, participants in both groups made more errors and reaction times (RTs) were longer when they were asked to look out for fearful faces compared with the other contexts. This bias against sensory evidence that runs counter to prior information was stronger in the patients, evidenced by a group by context interaction in accuracy and RTs for anger and fear respectively. CONCLUSIONS:Overall, the present data suggest an overdependence on prior expectations for threatening stimuli, reflecting belief inflexibility, in schizophrenia.

journal_name

Psychol Med

journal_title

Psychological medicine

authors

Barbalat G,Rouault M,Bazargani N,Shergill S,Blakemore SJ

doi

10.1017/S0033291712000384

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

2301-11

issue

11

eissn

0033-2917

issn

1469-8978

pii

S0033291712000384

journal_volume

42

pub_type

杂志文章
  • The impacts of COVID-19 outbreak on mental health in general population in different areas in China.

    abstract:BACKGROUND:This study aimed to explore the impacts of COVID-19 outbreak on mental health status in general population in different affected areas in China. METHODS:This was a comparative study including two groups of participants: (1) general population in an online survey in Ya'an and Jingzhou cities during the COVID...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291720004717

    authors: Ran MS,Gao R,Lin JX,Zhang TM,Chan SKW,Deng XP,Zhang BZ,Zhang XF,Huang GP,Pu DS,Bai JZ,Xu LX,Liu B

    更新日期:2020-12-10 00:00:00

  • A taxometric analysis of health anxiety.

    abstract:BACKGROUND:A long-standing issue in the health anxiety literature is the extent to which health anxiety is a dimensional or a categorical construct. This study explores this question directly using taxometric procedures. METHOD:Seven hundred and eleven working adults completed an index of health anxiety [the Whiteley ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291708003322

    authors: Ferguson E

    更新日期:2009-02-01 00:00:00

  • Psychiatrists' diagnoses of subthreshold depression in old age: frequency and correlates.

    abstract:BACKGROUND:Depressive syndromes not fulfilling the criteria for specified disorders (subthreshold depression, SD) may be clinically important. We aimed to study SD in old and very old age, in comparison with subjects with no depressive symptoms (NDS) and subjects with major depression (MD). METHODS:A community-based r...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291799002883

    authors: Geiselmann B,Linden M,Helmchen H

    更新日期:2001-01-01 00:00:00

  • Age at onset of non-affective psychosis in relation to cannabis use, other drug use and gender.

    abstract:BACKGROUND:Cannabis use is associated with an earlier age at onset of psychotic illness. The aim of the present study was to examine whether this association is confounded by gender or other substance use in a large cohort of patients with a non-affective psychotic disorder. METHOD:In 785 patients with a non-affective...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291712000062

    authors: Dekker N,Meijer J,Koeter M,van den Brink W,van Beveren N,Kahn RS,Linszen DH,van Os J,Wiersma D,Bruggeman R,Cahn W,de Haan L,Krabbendam L,Myin-Germeys I,GROUP Investigators.

    更新日期:2012-09-01 00:00:00

  • The comparison of latent variable models of non-psychotic psychiatric morbidity in four culturally diverse populations.

    abstract:BACKGROUND:Factor analysis has been employed to identify latent variables that are unifying constructs and that parsimoniously describe correlations among a related group of variables. Confirmatory factor analysis is used to test hypothesized factor structures for a set of variables; it can also, as in this paper be us...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291797005710

    authors: Jacob KS,Everitt BS,Patel V,Weich S,Araya R,Lewis GH

    更新日期:1998-01-01 00:00:00

  • Proton magnetic resonance spectroscopy: an in vivo method of estimating hippocampal neuronal depletion in schizophrenia.

    abstract::Diffuse loss of cortical volume and ventricular enlargement have been demonstrated in schizophrenia using imaging. In addition, histological studies have provided evidence that the number of neurons in the medial temporal lobe structures is reduced and that the cytoarchitecture is abnormal. In an attempt to correlate ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700033171

    authors: Maier M,Ron MA,Barker GJ,Tofts PS

    更新日期:1995-11-01 00:00:00

  • Individual differences in rumination in healthy and depressive samples: association with brain structure, functional connectivity and depression.

    abstract:BACKGROUND:Rumination is an important cognitive risk factor for onset and relapse of depression. However, no studies have employed a dimensional approach in investigating the neural correlates of rumination and the relationship with depression. METHOD:Non-clinical healthy subjects (n = 306), who completed the classica...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291715000938

    authors: Wang K,Wei D,Yang J,Xie P,Hao X,Qiu J

    更新日期:2015-10-01 00:00:00

  • Feedback learning and behavior problems after pediatric traumatic brain injury.

    abstract:BACKGROUND:Feedback learning is essential for behavioral development. We investigated feedback learning in relation to behavior problems after pediatric traumatic brain injury (TBI). METHOD:Children aged 6-13 years diagnosed with TBI (n = 112; 1.7 years post-injury) were compared with children with traumatic control (...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291716000106

    authors: Königs M,van Heurn LW,Vermeulen RJ,Goslings JC,Luitse JS,Poll-Thé BT,Beelen A,van der Wees M,Kemps RJ,Catsman-Berrevoets CE,Luman M,Oosterlaan J

    更新日期:2016-05-01 00:00:00

  • Elasticity and confabulation in schizophrenic delusions.

    abstract:BACKGROUND:This experiment examines two aspects of delusional cognition that have been reported clinically but not investigated empirically. These are the incorporation of potentially conflicting information into the recall of delusion-related scripts and the type and amount of material produced additional to that pres...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s003329170200538x

    authors: Simpson J,Done DJ

    更新日期:2002-04-01 00:00:00

  • A comparison of the utility of dimensional and categorical representations of psychosis. UK700 Group.

    abstract:BACKGROUND:The usefulness of any diagnostic scheme is directly related to its ability to provide clinically useful information on need for care. In this study, the clinical usefulness of dimensional and categorical representations of psychotic psychopathology were compared. METHOD:A total of 706 patients aged 16-65 ye...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0033291798008162

    authors: Van Os J,Gilvarry C,Bale R,Van Horn E,Tattan T,White I,Murray R

    更新日期:1999-05-01 00:00:00

  • Community outreach for untreated schizophrenia in rural India: a follow-up study of symptoms, disability, family burden and costs.

    abstract:BACKGROUND:In resource-poor countries, there remains an alarming treatment gap for people with schizophrenia, particularly those living in rural areas. Decentralization of mental health services, including community-based outreach programmes, represents one obvious strategy for bringing appropriate care to these commun...

    journal_title:Psychological medicine

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0033291704003551

    authors: Srinivasa Murthy R,Kishore Kumar KV,Chisholm D,Thomas T,Sekar K,Chandrashekari CR

    更新日期:2005-03-01 00:00:00

  • Spontaneous movement disorders in antipsychotic-naive patients with first-episode psychoses: a systematic review.

    abstract:BACKGROUND:Spontaneous movement disorders (SMDs), such as spontaneous dyskinesia and parkinsonism, have been described in patients with schizophrenia who have never been treated with antipsychotic medication. Their presence has been documented extensively in chronic schizophrenia but not at the time of illness onset. ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291708004716

    authors: Pappa S,Dazzan P

    更新日期:2009-07-01 00:00:00

  • Course and outcome of depressive disorders in primary care: a prospective 18-month study.

    abstract:BACKGROUND:Depressive disorders are known to often be chronic and recurrent both in the general population and in psychiatric settings. However, despite its importance for public health and services, the outcome of depression in primary care is not well known. METHOD:In The Vantaa Primary Care Depression Study (PC-VDS...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291709005182

    authors: Vuorilehto MS,Melartin TK,Isometsä ET

    更新日期:2009-10-01 00:00:00

  • Evolution of neuropsychological dysfunction during the course of schizophrenia and bipolar disorder.

    abstract:BACKGROUND:Neurocognitive dysfunction in schizophrenia (SZ), bipolar (BD) and related disorders represents a core feature of these illnesses, possibly a marker of underlying pathophysiology. Substantial overlap in domains of neuropsychological deficits has been reported among these disorders after illness onset. Howeve...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291710001042

    authors: Lewandowski KE,Cohen BM,Ongur D

    更新日期:2011-02-01 00:00:00

  • Healthy cognitive ageing in the Lothian Birth Cohort studies: marginal gains not magic bullet.

    abstract::In the face of shifting demographics and an increase in human longevity, it is important to examine carefully what is known about cognitive ageing, and to identify and promote possibly malleable lifestyle and health-related factors that might mitigate age-associated cognitive decline. The Lothian Birth Cohorts of 1921...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291717001489

    authors: Corley J,Cox SR,Deary IJ

    更新日期:2018-01-01 00:00:00

  • Depression, depressive symptoms, and rate of hippocampal atrophy in a longitudinal cohort of older men and women.

    abstract:BACKGROUND:Several studies have reported smaller hippocampal volume (HcV) in depression patients; however, the temporality of the association remains unknown. One proposed hypothesis is that depression may cause HcV loss. This study evaluates whether previous depression and recent depressive symptoms are associated wit...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714003055

    authors: Elbejjani M,Fuhrer R,Abrahamowicz M,Mazoyer B,Crivello F,Tzourio C,Dufouil C

    更新日期:2015-07-01 00:00:00

  • On establishing the validity of 'objective' data: can we rely on cross-interview agreement?

    abstract::It has been proposed that a high level of agreement between informants' reports about events and happenings ('objective' data) is a sound basis for establishing (a) the validity of the measure which is based on the reports, and (b) the nature of objective reality. In this paper it is argued that such agreement may not...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700047486

    authors: Platt S

    更新日期:1980-08-01 00:00:00

  • Parental representation in twins discordant for schizophrenia.

    abstract::Parental representation was assessed with the Parental Bonding Instrument (PBI) in 12 monozygotic (MZ) and 19 dizygotic (DZ) same-sexed twin pairs discordant for DSM-III-R schizophrenia. The schizophrenic twins reported less care and more overprotection from both parents than the non-schizophrenic co-twins. Multiple r...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700028439

    authors: Onstad S,Skre I,Torgersen S,Kringlen E

    更新日期:1993-05-01 00:00:00

  • Differential motivational responses to food and pleasurable cues in anorexia and bulimia nervosa: a startle reflex paradigm.

    abstract:BACKGROUND:Abnormal perceptions of food and shape underpin the cognitive behavioural model of eating disorders (EDs). The aim of this study was to investigate motivational processing of disorder-specific and standard emotional cues in anorexia (AN) and bulimia nervosa (BN) using startle eyeblink modulation (SEM). SEM w...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291706008129

    authors: Friederich HC,Kumari V,Uher R,Riga M,Schmidt U,Campbell IC,Herzog W,Treasure J

    更新日期:2006-09-01 00:00:00

  • Personality traits among currently eating disordered, recovered and never ill first-degree female relatives of bulimic and control women.

    abstract:BACKGROUND:A combined family study and recovered study design was utilized to examine several hypothesized relationships between personality and bulimia nervosa (BN). METHODS:We studied 47 women with a lifetime history of DSM-III-R BN (31 currently ill and 16 recovered), 44 matched control women (CW) with no history o...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291799002792

    authors: Lilenfeld LR,Stein D,Bulik CM,Strober M,Plotnicov K,Pollice C,Rao R,Merikangas KR,Nagy L,Kaye WH

    更新日期:2000-11-01 00:00:00

  • Assessing your mood online: acceptability and use of Moodscope.

    abstract:BACKGROUND:Moodscope is an entirely service-user-developed online mood-tracking and feedback tool with built-in social support, designed to stabilize and improve mood. Many free internet tools are available with no assessment of acceptability, validity or usefulness. This study provides an exemplar for future assessmen...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291712002280

    authors: Drake G,Csipke E,Wykes T

    更新日期:2013-07-01 00:00:00

  • Dysfunctional parenting as a risk factor to lifetime depression in a sample of employed Japanese adults: evidence for the 'affectionless control' hypothesis.

    abstract:BACKGROUND:Although many case-control studies have replicated an association between dysfunctional parenting and a lifetime diagnosis of depression, few epidemiological studies have explored the association. In addition, little is known about the association in non-western countries. METHODS:Using logistic regression ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291797006430

    authors: Sato T,Sakado K,Uehara T,Narita T,Hirano S,Nishioka K,Kasahara Y

    更新日期:1998-05-01 00:00:00

  • Incremental benefits and cost of coordinated anxiety learning and management for anxiety treatment in primary care.

    abstract:BACKGROUND:Improving the quality of mental health care requires integrating successful research interventions into 'real-world' practice settings. Coordinated Anxiety Learning and Management (CALM) is a treatment-delivery model for anxiety disorders encountered in primary care. CALM offers cognitive behavioral therapy ...

    journal_title:Psychological medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1017/S0033291711002893

    authors: Joesch JM,Sherbourne CD,Sullivan G,Stein MB,Craske MG,Roy-Byrne P

    更新日期:2012-09-01 00:00:00

  • The incidence and prevalence of pervasive developmental disorders: a Danish population-based study.

    abstract:BACKGROUND:Based on prevalence studies and the few incidence studies of pervasive developmental disorders (PDDs) the prevalence and incidence of these disorders have been claimed to be increasing. METHOD:The annual and age-specific prevalence and incidence rates of childhood autism, atypical autism, Asperger's disorde...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704002387

    authors: Lauritsen MB,Pedersen CB,Mortensen PB

    更新日期:2004-10-01 00:00:00

  • Behavioural and neurocognitive responses to sad facial affect are attenuated in patients with mania.

    abstract:BACKGROUND:The processing of facial emotion involves a distributed network of limbic and paralimbic brain structures. Many of these regions are also implicated in the pathophysiology of mood disorders. Behavioural data indicate that depressed subjects show a state-related positive recognition bias for faces displaying ...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291704002557

    authors: Lennox BR,Jacob R,Calder AJ,Lupson V,Bullmore ET

    更新日期:2004-07-01 00:00:00

  • Parental death in childhood and risk of adult depressive disorders: a review.

    abstract::The authors review the evidence that parental death in childhood predisposes to depressive disorders in later life. The findings in general are quite inconsistent; this is due in part to the methodological limitations of most studies, principally that of inadequate control of potentially confounding variables. Where e...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/s0033291700044044

    authors: Tennant C,Bebbington P,Hurry J

    更新日期:1980-05-01 00:00:00

  • A Swedish national twin study of criminal behavior and its violent, white-collar and property subtypes.

    abstract:BACKGROUND:We sought to clarify the etiological contribution of genetic and environmental factors to total criminal behavior (CB) measured as criminal convictions in men and women, and to violent (VCB), white-collar (WCCB) and property criminal behavior (PCB) in men only. METHOD:In 21 603 twin pairs from the Swedish T...

    journal_title:Psychological medicine

    pub_type: 杂志文章

    doi:10.1017/S0033291714002098

    authors: Kendler KS,Maes HH,Lönn SL,Morris NA,Lichtenstein P,Sundquist J,Sundquist K

    更新日期:2015-08-01 00:00:00

  • Does Internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials.

    abstract:BACKGROUND:Almost nothing is known about the potential negative effects of Internet-based psychological treatments for depression. This study aims at investigating deterioration and its moderators within randomized trials on Internet-based guided self-help for adult depression, using an individual patient data meta-ana...

    journal_title:Psychological medicine

    pub_type: 杂志文章,meta分析

    doi:10.1017/S0033291716001562

    authors: Ebert DD,Donkin L,Andersson G,Andrews G,Berger T,Carlbring P,Rozenthal A,Choi I,Laferton JA,Johansson R,Kleiboer A,Lange A,Lehr D,Reins JA,Funk B,Newby J,Perini S,Riper H,Ruwaard J,Sheeber L,Snoek FJ,Titov N,Ü

    更新日期:2016-10-01 00:00:00

  • Pseudohallucinations: a conceptual history.

    abstract::The term 'pseudohallucination' is currently used to name imaginal experiences whose relationship to one another and to hallucinations 'proper' remains obscure. Clinicians, including specialists in psychopathology, disagree on how pseudohallucination must be defined and on its diagnostic role. Empirical research is unl...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/s0033291700037776

    authors: Berrios GE,Dening TR

    更新日期:1996-07-01 00:00:00

  • The neuroscience of free will: implications for psychiatry.

    abstract::Belief in free will has been a mainstay in philosophy throughout history, grounded in large part in our intuitive sense that we consciously control our actions and could have done otherwise. However, psychology and psychiatry have long sought to uncover mechanistic explanations for human behavior that challenge the no...

    journal_title:Psychological medicine

    pub_type: 杂志文章,评审

    doi:10.1017/S0033291713002985

    authors: Pierre JM

    更新日期:2014-09-01 00:00:00