Sertoli cell-germ cell interactions and TGF beta 1 expression and secretion in vitro.

abstract：:The 3-deoxy-octulosonic acid-containing trisaccharide was isolated from the carbohydrate material obtained after the acid hydrolysis of lipopolysaccharides of Hafnia alvei strains 2 and 1211 using gel filtration. For purification the trisaccharide fraction was rechromatographed on a Bio-Gel P2 column. On the basis of ...

journal_title：Biochemical and biophysical research communications

authors： Katzenellenbogen E,Gamian A,Romanowska E,Dabrowski U,Dabrowski J

更新日期：1993-08-16 00:00:00

abstract：:Interleukin (IL)-23 plays a predominant role in the development of autoimmune diseases by inducing IL-17-producing helper T (Th17) cells. The receptor for IL-23 consists of a heterodimer composed of the IL-12 receptor beta1 (IL-12Rbeta1) and the IL-23 receptor (IL-23R), which is mainly expressed on Th17 cells. A recen...

journal_title：Biochemical and biophysical research communications

authors： Sonobe Y,Liang J,Jin S,Zhang G,Takeuchi H,Mizuno T,Suzumura A

更新日期：2008-05-23 00:00:00

abstract：:The regulatory mechanisms of most cyclin dependent protein kinases (CDKs) are well understood and are highly conserved in eukaryotes. CDKs from the malaria parasite, Plasmodium falciparum, appear to be regulated in a similar manner with regard to cyclin binding and phosphorylation. In order to further understand their...

journal_title：Biochemical and biophysical research communications

authors： Li Z,Le Roch K,Geyer JA,Woodard CL,Prigge ST,Koh J,Doerig C,Waters NC

更新日期：2001-11-16 00:00:00

abstract：:Reactive oxygen species (ROS) are important factors mediating aging according to the free radical theory of aging. Few studies have systematically measured ROS levels in relationship to aging, partly due to the lack of tools for detection of specific ROS in live animals. By using the H₂O₂-specific fluorescence probe P...

journal_title：Biochemical and biophysical research communications

authors： Fu X,Tang Y,Dickinson BC,Chang CJ,Chang Z

更新日期：2015-03-20 00:00:00

abstract：:We developed the real-time PCR quantification of endothelin-A (ET-A) and endothelin-B (ET-B) receptor genes and present their relative expression levels in various adult tissues and during development in mouse using the 2(-Delta Delta C(T)) method. ET-A and ET-B receptors were detected in all tissues examined. Gene ex...

journal_title：Biochemical and biophysical research communications

authors： Adur J,Takizawa S,Quan J,Uchide T,Saida K

更新日期：2003-06-06 00:00:00

abstract：:Mycobacterium tuberculosis, the causative agent of tuberculosis disease, is one among the deadliest pathogens in the world. Due to long treatment regimen, HIV co-infection, persistence of bacilli in latent form and development of XDR and TDR strains of Mtb, tuberculosis has posed serious concerns for managing the dise...

journal_title：Biochemical and biophysical research communications

authors： Gopalan A,Bhagavat R,Chandra N,Subbarao SH,Raja A,Bethunaickan R

更新日期：2018-02-12 00:00:00

abstract：:The effect of transforming growth factor-beta (TGF-beta) on the endogenous protein phosphorylation caused by phorbol 12-myristate 13-acetate (PMA), a potent activator of protein kinase C (PKC), was examined in primary cultured mouse epidermal cells. PMA markedly stimulates phosphorylation of endogenous proteins, i.e. ...

journal_title：Biochemical and biophysical research communications

authors： Nishikawa K,Yamamoto S,Nagumo H,Otsuka C,Kato R

更新日期：1993-05-28 00:00:00

abstract：:Kinetics measurements of the electron transfer between ferricytochrome c and liposomal ferrocytochrome c1 (with and without the hinge protein) were performed. The observed rate constants(kobs) of electron transfer between liposomal ferrocytochrome c1 and ferricytochrome c at different ionic strengths were measured in ...

journal_title：Biochemical and biophysical research communications

authors： Kim CH,King TE,Balny C

更新日期：1989-08-30 00:00:00

abstract：:The serine/threonine kinase mammalian target of rapamycin (mTOR) is stimulated by insulin, growth factors and nutrients and confers survival of several cell types. The kinase has previously been shown to stimulate amino acid uptake. In neurons, the cellular uptake of glutamate by the excitatory amino-acid transporters...

journal_title：Biochemical and biophysical research communications

authors： Almilaji A,Pakladok T,Guo A,Munoz C,Föller M,Lang F

更新日期：2012-05-04 00:00:00

abstract：:A method for the extraction and purification of PrP(C), in its native monomeric form, from outdated human platelet concentrates is described. Both calcium ionophore platelet activation and lysis in Triton X-100 were evaluated as methods for the extraction of soluble platelet PrP(C) in its monomeric form. Following pla...

journal_title：Biochemical and biophysical research communications

authors： Jones M,Head MW,Connolly JG,Farquhar CF,Hornsey VS,Pepper DS,MacGregor IR

更新日期：2005-09-16 00:00:00

abstract：:A marked reduction of the proliferative capability after a mitogenic stimulus and a dramatic decrease of the capacity to repair DNA damages were found in lymphocytes from iron overloaded rats. These immunological parameters were not significantly different from controls in peripheral blood lymphocytes from patients wi...

journal_title：Biochemical and biophysical research communications

authors： Pietrangelo A,Cossarizza A,Monti D,Ventura E,Franceschi C

更新日期：1988-07-29 00:00:00

abstract：:Saccharides used in clinical nutrients and the hyperglycemia status may facilitate tumor growth and aggravate cancer patients' outcome. As glucose, fructose and maltodextrin are widely used in clinical practice, various effects on tumor progress among them remain unknown. Six kinds of tumor cell lines were included in...

journal_title：Biochemical and biophysical research communications

authors： Yu C,Lv B,Min S,Ren L,Yu J

更新日期：2020-05-07 00:00:00

abstract：:Sulfation is an important pathway in the metabolism of thyroid hormones. Sulfated iodothyronines are elevated in nonthyroidal illnesses and in the normal human fetal circulation. We assayed and characterized COS-1 cell expressed recombinant human liver dehydroepiandrosterone sulfotransferase (DHEA ST or SULT2A1) and e...

journal_title：Biochemical and biophysical research communications

authors： Li X,Anderson RJ

更新日期：1999-10-05 00:00:00

abstract：:ADAM17 is known to contribute to the immune system through its shedding of tumor necrosis factor alpha (TNFα). However, the role of ADAM17 in B cell biology is not well characterized. To determine whether B cell ADAM17 contributes to T cell-independent humoral immune responses, we crossed CD19 Cre transgenic mice with...

journal_title：Biochemical and biophysical research communications

authors： Lownik JC,Wimberly JL,Takahashi-Ruiz L,Martin RK

更新日期：2020-02-05 00:00:00

abstract：:In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action of this hormone during ischemia. Rat hearts were perfused ex vivo with an ischemia/reperfusion Lan...

journal_title：Biochemical and biophysical research communications

authors： Díaz A,Humeres C,González V,Gómez MT,Montt N,Sanchez G,Chiong M,García L

更新日期：2015-11-13 00:00:00

abstract：:FOXK2, which belongs to the fork head DNA binding protein family, has been shown to play a critical role in tumorigenesis. Here, we detected FOXK2 expression and its clinical significance in colorectal cancer, which has not been fully investigated before. Results from public database and our cohort indicated that FOXK...

journal_title：Biochemical and biophysical research communications

authors： Qian Y,Xia S,Feng Z

更新日期：2017-01-29 00:00:00

abstract：:To investigate molecular mechanisms linking inflammation with neurodegeneration, we treated neuronal cultures with prostaglandins (PGs), which are mediators of inflammation. PGA1, D2, J2, and Delta12-PGJ2, but not PGE2, reduced the viability and raised the levels of ubiquitinated proteins in the neuronal cells. PGJ2 a...

journal_title：Biochemical and biophysical research communications

authors： Li Z,Melandri F,Berdo I,Jansen M,Hunter L,Wright S,Valbrun D,Figueiredo-Pereira ME

更新日期：2004-07-09 00:00:00

abstract：:Using genomic restriction analysis of 14 unrelated patients with salt-losing congenital adrenal hyperplasia, we identified three different CA21HB mutation patterns: no detectable restriction fragment abnormalities (16/28 haplotypes), deletion of the active CA21HB gene (9/28), and apparent conversion of the active CA21...

journal_title：Biochemical and biophysical research communications

authors： Jospe N,Donohoue PA,Van Dop C,McLean RH,Bias WB,Migeon CJ

更新日期：1987-02-13 00:00:00

abstract：:In the presence of Mg-GTP, the rat liver guanylate cyclase, in either intact membranes or trypsin solubilized form, was stimulated by protoporphyrin IX 6 to 10-fold. However, when Mn-GTP was the substrate, protoporphyrin IX activated the membrane-bound guanylate cyclase only 50%, in contrast to the marked activation r...

journal_title：Biochemical and biophysical research communications

authors： Lacombe ML,Eberentz-Lhomme C

更新日期：1983-10-14 00:00:00

abstract：:The exposure of organ cultured pineal glands of Syrian hamsters to forskolin, an adenylate cyclase activator, caused marked increases in serotonin N-acetyltransferase activity and melatonin content in a dose-related manner (1-100 microM) when glands were collected in the second half of the dark period. However, additi...

journal_title：Biochemical and biophysical research communications

authors： Santana C,Guerrero JM,Reiter RJ,Gonzalez-Brito A,Menendez-Pelaez A

更新日期：1988-08-30 00:00:00

abstract：:Hsa-microRNA-187-3p (miR-187-3p) has recently been discovered having anticancer efficacy in different organs. However, the role of miR-187-3p on non-small cell lung cancer (NSCLC) is still ambiguous. In this study, we investigated the role of miR-187-3p on the development of NSCLC. The results indicated that miR-187-3...

journal_title：Biochemical and biophysical research communications

authors： Sun C,Li S,Yang C,Xi Y,Wang L,Zhang F,Li D

更新日期：2016-02-26 00:00:00

abstract：:Alpha-bulnesene is a sesquiterpenoid isolated from the water extract of Pogostemon cablin. It showed a potent and concentration-dependent inhibitory effect on platelet-activating factor (PAF) and arachidonic acid (AA) induced rabbit platelet aggregation. In a radioligand binding assay for the PAF receptor, alpha-bulne...

journal_title：Biochemical and biophysical research communications

authors： Hsu HC,Yang WC,Tsai WJ,Chen CC,Huang HY,Tsai YC

更新日期：2006-07-07 00:00:00

abstract：:Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1alpha subunit of the pyruvate dehydrogenase complex (PDC). Sequence analysis of cloned PDKs led to the proposal that they are mechanistically related to prokaryotic 2-component His-kinases. The reaction mechanism of protein His-kinases involves auto...

journal_title：Biochemical and biophysical research communications

authors： Mooney BP,David NR,Thelen JJ,Miernyk JA,Randall DD

更新日期：2000-01-19 00:00:00

abstract：:Using different maximum-likelihood models of adaptive evolution, signatures of natural selective pressure, operating across the naphthalene family of dioxygenases, were examined. A lineage- and branch-site specific combined analysis revealed that purifying selection pressure dominated the evolutionary history of the e...

journal_title：Biochemical and biophysical research communications

authors： Dutta A,Chakraborty J,Dutta TK

更新日期：2013-10-11 00:00:00

abstract：:Streptococcus pneumoniae is a pathogenic bacterium that can cause severe invasive diseases, such as pneumonia, otitis media and meningitis. The pro-inflammatory cytokine, IL-1β, has been reported to play important role in host defense against S. pneumoniae. The mechanism of IL-1β maturation and secretion in macrophage...

journal_title：Biochemical and biophysical research communications

authors： Zhang T,Du H,Feng S,Wu R,Chen T,Jiang J,Peng Y,Ye C,Fang R

更新日期：2019-06-04 00:00:00

abstract：:Transgenic mouse which produces human alpha-fetoprotein (AFP) ubiquitously was used to study carbohydrate structures of AFP produced by various tissues as well as that in the serum. A series of tissues from the transgenic mouse were cultured in vitro and the AFP produced was analyzed by affinity electrophoreses with 4...

journal_title：Biochemical and biophysical research communications

authors： Koyama Y,Sakai M,Kitagawa T,Taketa K,Nishi S

更新日期：1996-06-25 00:00:00

abstract：:Possible mediators of descending inhibition in the rat proximal colon were studied. Localized distension with a small balloon caused relaxation of the circular muscle on the anal side of the distended region. This relaxation was still observed after the colonic segment had been desensitized to ATP, neurotensin and vas...

journal_title：Biochemical and biophysical research communications

authors： Hata F,Ishii T,Kanada A,Yamano N,Kataoka T,Takeuchi T,Yagasaki O

更新日期：1990-11-15 00:00:00

abstract：:Barnacles are notorious marine fouling organisms. Their successful attachment to a substrate requires that they search for an appropriate habitat during their cyprid stage. A chemical cue called SIPC (Settlement-Inducing Protein Complex) has been shown to play a key role in the induction of cyprid gregarious settlemen...

journal_title：Biochemical and biophysical research communications

authors： Zhang X,Liang C,Song J,Ye Z,Wu W,Hu B

更新日期：2020-05-14 00:00:00

abstract：:In cultures of human foreskin fibroblasts most of the cell surface binding sites for 2-chain urokinase are masked and can be exposed by 10 min. incubation on ice at pH 2.5 (A. Bajpai and J.B. Baker (1985), Biochem. Biophys. Res. Commun.133, 475-482). Here we show that incubation on ice at pH 2.5 also releases from the...

journal_title：Biochemical and biophysical research communications

authors： Bajpai A,Baker JB

更新日期：1985-12-31 00:00:00

abstract：:Thioredoxin-interacting protein (TXNIP) emerges as a central regulator for glucose homeostasis, which goes awry in diabetic subjects. Endothelial dysfunction is considered the earliest detectable stage of cardiovascular disease (CVD), a major complication of diabetes. Here, we hypothesize that TXNIP may promote endoth...

journal_title：Biochemical and biophysical research communications

authors： Li X,Kover KL,Heruth DP,Watkins DJ,Guo Y,Moore WV,He LG,Zang M,Clements MA,Yan Y

更新日期：2017-11-04 00:00:00