当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Combined usage of monosaccharides with polysaccharides may decelerate tumor growth and malignance versus solely using a certain kind of saccharide.

Combined usage of monosaccharides with polysaccharides may decelerate tumor growth and malignance versus solely using a certain kind of saccharide.

Abstract：

:Saccharides used in clinical nutrients and the hyperglycemia status may facilitate tumor growth and aggravate cancer patients' outcome. As glucose, fructose and maltodextrin are widely used in clinical practice, various effects on tumor progress among them remain unknown. Six kinds of tumor cell lines were included in this study. We evaluated the discrepant effects of sugars on tumor growth by nude mice xenograft model, wound-healing assay and cell counting kit-8 test were for measuring the migration and proliferation capability in vitro, and oral gavage on C57BL/6 N mice was applied to assess the fluctuation of blood glucose level. Results showed that though tumor cells presented discrepant sensitivity to different saccharides, the combined usage of glucose, fructose with maltodextrin has milder effect on tumor progression and moderate effect on blood glucose fluctuation, which may indicate a brighter option on saccharides selection for tumor patients.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Yu C,Lv B,Min S,Ren L,Yu J

doi

10.1016/j.bbrc.2020.01.083

subject

Has Abstract

pub_date

2020-05-07 00:00:00

pages

800-805

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(20)30152-2

journal_volume

525

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Purification of the yellow fluorescent protein from Vibrio fischeri and identity of the flavin chromophore.

    abstract：:A low molecular weight protein (approximately 25,000 D) exhibiting a yellow fluorescence emission peaking at approximately 540 nm was isolated from Vibrio fischeri (strain Y-1) and purified to apparent homogeneity. FMN is the chromophore, but it exhibits marked red shifts in both the absorption (lambda max = 380, 460 ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)90696-6

    authors： Macheroux P,Schmidt KU,Steinerstauch P,Ghisla S,Colepicolo P,Buntic R,Hastings JW

    更新日期：1987-07-15 00:00:00

  • Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice.

    abstract：:The effect of thyroid-stimulating hormone receptor (TSHR) on hepatic lipid accumulation in vivo is not fully understood. Further, while TSHR in the thyroid has been studied extensively, whether and how the absence of TSHR in the liver affects systemic energy metabolism has not yet been reported. To examine these effec...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.01.187

    authors： Zhou L,Wu K,Zhang L,Gao L,Chen S

    更新日期：2018-02-26 00:00:00

  • Cholesterol depletion induces autophagy.

    abstract：:Autophagy is a mechanism to digest cells' own components, and its importance in many physiological and pathological processes is being recognized. But the molecular mechanism that regulates autophagy is not understood in detail. In the present study, we found that cholesterol depletion induces macroautophagy. The cell...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.10.042

    authors： Cheng J,Ohsaki Y,Tauchi-Sato K,Fujita A,Fujimoto T

    更新日期：2006-12-08 00:00:00

  • AGR2 is a target of canonical Wnt/β-catenin signaling and is important for stemness maintenance in colorectal cancer stem cells.

    abstract：:Colorectal cancer is one of the leading causes of cancer-related deaths. Due to relapse after current therapy regimens, cancer stem cells (CSCs) are being studied to target this small tumor-initiating population. Anterior gradient 2 (AGR2), a disulfide isomerase protein, is a well-known pro-oncogenic/metastatic oncoge...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.05.154

    authors： Dahal Lamichane B,Jung SY,Yun J,Kang S,Kim DY,Lamichane S,Kim YJ,Park JH,Jang WB,Ji ST,Dehua L,Ha JS,Kim YH,Kwon SM

    更新日期：2019-08-06 00:00:00

  • Intersubunit crosslinking of the heterotetrameric proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli defines intersubunit contacts between transmembrane helices of the beta subunits.

    abstract：:The proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli is composed of two types of subunits, alpha and beta, organized as an alpha(2)beta(2) tetramer. The protein contains three recognizable domains, of which domain II is the transmembrane region of the molecule containing the pathway for pr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.4142

    authors： Hou C,Bragg PD

    更新日期：2001-01-19 00:00:00

  • Solution structure of intracellular signal-transducing peptide derived from human beta(2)-adrenergic receptor.

    abstract：:The structure of intracellular third loop peptide (betaIII-2: RRSSKFCLKEKKALK) was studied by CD and NMR spectroscopy. According to the CD study, this peptide forms a helix in the TFE solution. The three-dimensional molecular structure in TFE was determined by the 2D (1)H NMR spectroscopy. The structure consists of a ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2002.6606

    authors： Okuda A,Matsumoto O,Akaji M,Taga T,Ohkubo T,Kobayashi Y

    更新日期：2002-03-15 00:00:00

  • Macrophage paraoxonase 1 (PON1) binding sites.

    abstract：:Paraoxonase 1 (PON1), an HDL-associated esterase, is known to possess anti-oxidant and anti-atherogenic properties. PON1 was shown to protect macrophages from oxidative stress, to inhibit macrophage cholesterol biosynthesis, and to stimulate HDL-mediated cholesterol efflux from the cells. The aim of the present study ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.08.106

    authors： Efrat M,Aviram M

    更新日期：2008-11-07 00:00:00

  • Salvianolic acid A protects human SH-SY5Y neuroblastoma cells against H₂O₂-induced injury by increasing stress tolerance ability.

    abstract：:Salvianolic acid A (Sal A) is a polyphenol extracted from the root of the Salvia miltiorrhiza bunge. Hydrogen peroxide (H(2)O(2)) is a major reactive oxygen species (ROS), which has been implicated in stroke and other neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In this study, we ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.04.021

    authors： Zhang HA,Gao M,Zhang L,Zhao Y,Shi LL,Chen BN,Wang YH,Wang SB,Du GH

    更新日期：2012-05-11 00:00:00

  • Relative positioning of the T cell and B cell determinants on an immunogenic peptide: its influence on antibody response.

    abstract：:A tryptic peptide of bovine beta-casein (amino acid residues 184-202) was used as a model antigen to investigate how the relative position of the (helper) T cell and B cell determinants on a protein antigen influences the antibody response. Immunization with the peptide elicited a considerably higher anti-peptide resp...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90402-9

    authors： Hachimura S,Enomoto A,Kaminogawa S

    更新日期：1990-06-15 00:00:00

  • Regulatory CD8+ T cells induced by exposure to all-trans retinoic acid and TGF-beta suppress autoimmune diabetes.

    abstract：:Antigen-specific regulatory CD4(+) T cells have been described but there are few reports on regulatory CD8(+) T cells. We generated islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)-specific regulatory CD8(+) T cells from 8.3-NOD transgenic mice. CD8(+) T cells from 8.3-NOD splenocytes were...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.02.176

    authors： Kishi M,Yasuda H,Abe Y,Sasaki H,Shimizu M,Arai T,Okumachi Y,Moriyama H,Hara K,Yokono K,Nagata M

    更新日期：2010-03-26 00:00:00

  • Network signatures of cellular immortalization in human lymphoblastoid cell lines.

    abstract：:Human lymphoblastoid cell line (LCL) has been used as an in vitro cell model in genetic and pharmacogenomic studies, as well as a good model for studying gene expression regulatory machinery using integrated genomic analyses. In this study, we aimed to identify biological networks of LCL immortalization from transcrip...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.10.081

    authors： Shim SM,Jung SY,Nam HY,Kim HR,Lee MH,Kim JW,Han BG,Jeon JP

    更新日期：2013-11-15 00:00:00

  • Thermodynamics of i-tetraplex formation in the nuclease hypersensitive element of human c-myc promoter.

    abstract：:More than 85% of c-myc transcription is controlled by the nuclease hypersensitive element III(1) upstream of the P1 promoter of this oncogene. The purine-rich sequence in the anti-sense strand forms a G-quadruplex, which has been recently implicated in colorectal cancer, and is proposed as a silencer element [Proc. Na...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.06.074

    authors： Mathur V,Verma A,Maiti S,Chowdhury S

    更新日期：2004-08-06 00:00:00

  • Cloning and characterization of the 5'-flanking region for the mouse phospholipase C-delta1 gene.

    abstract：:To date, little is known about the molecular mechanisms controlling the regulation of phospholipase C-delta1 (PLC-delta1) gene expression. To understand the mechanisms responsible for the regulation of PLC-delta1 gene expression, the 5'-flanking region of the mouse PLC-delta1 gene was isolated from a mouse genomic DNA...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2930

    authors： Kim JK,Lee WK,Nam HW,Lee KH,Han H,Rha HK,Jun TY,Kim KS,Choi CR

    更新日期：2000-06-24 00:00:00

  • Helix stabilization in the C-terminal peptide of chicken riboflavin carrier protein enhances immunogenicity and prolongs contraceptive potential as an epitope-based vaccine in female rats.

    abstract：:Earlier investigations have shown that (a) antibodies against a carrier-coupled 20-residue synthetic peptide (C-20), (200)HACQKKLLKFEALQQEEGEE(219), corresponding to the C-terminal partially helical sequence of chicken riboflavin carrier protein (RCP; 219 AA) curtail pregnancy in mammals and (b) helix stabilization by...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5571

    authors： Subramanian S,Karande AA,Adiga PR

    更新日期：2001-09-14 00:00:00

  • Pontine norepinephrine defects in Mecp2-null mice involve deficient expression of dopamine beta-hydroxylase but not a loss of catecholaminergic neurons.

    abstract：:Rett syndrome is a neurodevelopmental disorder caused by Mecp2 gene mutations. In RTT patients and Mecp2-null (Mecp2(-/Y)) mice, norepinephrine (NE) content drops significantly, which may play a role in breathing arrhythmia, sleep disorders and sudden death. However, the underlying mechanisms for the NE defect are not...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.02.156

    authors： Zhang X,Su J,Rojas A,Jiang C

    更新日期：2010-04-02 00:00:00

  • Conserved CA-rich motifs in gene promoters of Pt x tMYB021-responsive secondary cell wall carbohydrate-active enzymes in Populus.

    abstract：:In order to understand gene regulation during wood formation, we cloned a MYB46-like gene in hybrid aspen, Populus tremula x tremuloides, called Pt x tMYB021. Phylogenetic and paired identity analysis of MYB46-like genes in Populus and Arabidopsis reveals relationships between paralogous pairs of Populus MYB46-like pr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.03.101

    authors： Winzell A,Aspeborg H,Wang Y,Ezcurra I

    更新日期：2010-04-09 00:00:00

  • Leber's hereditary optic neuropathy is associated with the mitochondrial ND6 T14484C mutation in three Chinese families.

    abstract：:We report here the clinical, genetic, and molecular characterization of three Chinese families with maternally transmitted Leber's hereditary optic neuropathy (LHON). Clinical and genetic evaluations revealed the variable severity and age-of-onset in visual impairment in these families. In the affected matrilineal rel...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.06.075

    authors： Sun YH,Wei QP,Zhou X,Qian Y,Zhou J,Lu F,Qu J,Guan MX

    更新日期：2006-08-18 00:00:00

  • The effect of myotonic dystrophy transcript levels and location on muscle differentiation.

    abstract：:In myotonic dystrophy type I (DM1), nuclear retention of mutant DMPK transcripts compromises muscle cell differentiation. Although several reports have identified molecular defects in myogenesis, it remains still unclear how exactly the retention of the mutant transcripts induces this defect. We have recently created ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.10.031

    authors： Mastroyiannopoulos NP,Chrysanthou E,Kyriakides TC,Uney JB,Mahadevan MS,Phylactou LA

    更新日期：2008-12-12 00:00:00

  • Interaction of myosin subfragment-1 with F- and G-actin in equilibrium.

    abstract：:The structural changes of the F-actin-myosin head (S1) complex during the cross-bridge cycle are essential in muscle contraction. Although a large body of evidence has accumulated showing that the actin: S1 stoichiometry in the decorated F-actin-S1 filament is 1:1 at saturation by S1, a recent report by Andreev and Bo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80285-2

    authors： Carlier MF,Didry D

    更新日期：1992-03-31 00:00:00

  • Cardiomyocyte lipotoxicity is mediated by Il-6 and causes down-regulation of PPARs.

    abstract：:Here we sought to evaluate the effect of palmitate on cytokine and PPAR activity/expression. We investigated the effect of BSA conjugated palmitate and oleate on PPAR activity, PPAR-α and δ expression, as well as the expression of cytokines and key factors responsible for β-oxidation by qRT-PCR and western blotting in...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.02.062

    authors： Haffar T,Bérubé-Simard FA,Bousette N

    更新日期：2015-03-27 00:00:00

  • Identification of tick periviscerokinin, the first neurohormone of Ixodidae: single cell analysis by means of MALDI-TOF/TOF mass spectrometry.

    abstract：:The first peptidergic neurohormone from the ticks Ixodes ricinus and Boophilus microplus has been identified by using a combination of immunocytochemistry and mass spectrometric analysis of single cells. The novel peptide (Ixori-PVK, PALIPFPRV-NH2) shows a high sequence homology with members of the insect periviscerok...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.10.165

    authors： Neupert S,Predel R,Russell WK,Davies R,Pietrantonio PV,Nachman RJ

    更新日期：2005-12-30 00:00:00

  • Activin pathway enhances colorectal cancer stem cell self-renew and tumor progression.

    abstract：:Activin belongs to transforming growth factor (TGF)-β super family of growth and differentiation factors and activin pathway participated in broad range of cell process. Studies elaborated activin pathway maintain pluripotency in human stem cells and suggest that the function of activin/nodal signaling in self-renew w...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.09.146

    authors： Liu R,Wang JH,Xu C,Sun B,Kang SO

    更新日期：2016-10-28 00:00:00

  • Stimulation by oleic acid of incorporation of L-[4,5-3H]leucine into very low density lipoprotein apoprotein by the isolated perfused rat liver.

    abstract：:Livers from normal fed or fasted (24h) rats were perfused in vitro to determine whether fatty acid affects the biosynthesis of very low density lipoprotein (VLDL) apoprotein. Oleate stimulated VLDL triacylglycerol output and increased incorporation of L-[4,5-3H]leucine into VLDL apoprotein in both the fed and fasted g...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)90983-0

    authors： Salam WH,Wilcox HG,Heimberg M

    更新日期：1985-10-15 00:00:00

  • A comparative kinetic analysis of the reactivity of plant, horse, and human respiratory cytochrome c towards cytochrome c oxidase.

    abstract：:Two synthetic genes coding for human and Arabidopsis cytochrome c, respectively, have been designed and constructed, and the recombinant proteins have been over-expressed in Escherichia coli cells. Thus a comparative analysis of the two heme proteins, including horse cytochrome c as a reference, has been performed. In...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.06.022

    authors： Rodríguez-Roldán V,García-Heredia JM,Navarro JA,Hervás M,De la Cerda B,Molina-Heredia FP,De la Rosa MA

    更新日期：2006-08-04 00:00:00

  • Regulation of Bcl-2 protein expression during oxidative stress in neuronal and in endothelial cells.

    abstract：:The relationship between oxidative stress and Bcl-2 expression was investigated in two different experimental models of oxidative stress. Acute oxidative stress was assessed by measuring, with fluorescence microscopy and cytofluorimetry, the increase in fluorescence of the oxidation-sensitive probe dihydrorhodamine 12...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.0928

    authors： Longoni B,Boschi E,Demontis GC,Marchiafava PL,Mosca F

    更新日期：1999-07-05 00:00:00

  • Structure, chromosomal location, and expression profile of EXTR1 and EXTR2, new members of the multiple exostoses gene family.

    abstract：:Hereditary multiple exostoses (EXT) is an autosomal dominant disorder that is characterized by the appearance of multiple outgrowths of the long bones (exostoses) at their epiphyses. Genetical heterogeneities have segregated at least on chromosome 8, 11, and 19 and been designated EXT1, EXT2, and EXT3, respectively. R...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.8062

    authors： Saito T,Seki N,Yamauchi M,Tsuji S,Hayashi A,Kozuma S,Hori T

    更新日期：1998-02-04 00:00:00

  • Long-term phorbol ester treatment dissociates phospholipase D activation from phosphoinositide hydrolysis and prostacyclin synthesis in endothelial cells stimulated with bradykinin.

    abstract：:Bovine pulmonary artery endothelial cells (BPAEC) were prelabeled with [3H]choline or [3H]myristic acid to selectively label endogenous phosphatidylcholine. BPAEC were stimulated with ATP and bradykinin (BK), and phospholipase D (PLD) activation was detected as a 4-fold increase in [3H]choline in cells prelabeled with...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)91072-3

    authors： Martin TW,Feldman DR,Goldstein KE,Wagner JR

    更新日期：1989-11-30 00:00:00

  • Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from Plasmodium falciparum.

    abstract：:The important role of pyruvate kinase during malarial infection has prompted the cloning of a cDNA encoding Plasmodium falciparum pyruvate kinase (pfPyrK), using mRNA from intraerythrocytic-stage malaria parasites. The full-length cDNA encodes a protein with a computed molecular weight of 55.6 kDa and an isoelectric p...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.11.018

    authors： Chan M,Sim TS

    更新日期：2005-01-07 00:00:00

  • Activation of AMP-activated protein kinase by compound 991 protects osteoblasts from dexamethasone.

    abstract：:Dexamethasone (Dex) induces direct cytotoxicity to cultured osteoblasts. The benzimidazole derivative compound 991 ("C991") is a novel and highly-efficient AMP-activated protein kinase (AMPK) activator. Here, in both MC3T3-E1 osteoblastic cells and primary murine osteoblasts, treatment with C991 activated AMPK signali...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.11.132

    authors： Xu YY,Chen FL,Ji F,Fei HD,Xie Y,Wang SG

    更新日期：2018-01-01 00:00:00

  • Proteasome-dependent degradation of cytosolic chaperonin CCT.

    abstract：:The chaperonin containing t-complex polypeptide 1 (CCT) is a heterooligomeric molecular chaperone that assists in the folding of actin, tubulin, and other cytosolic proteins. We show here that degradation of CCT in mammalian cells is inhibited by a proteasome-specific inhibitor, lactacystin. When CCT synthesis was inh...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.4011

    authors： Yokota S,Kayano T,Ohta T,Kurimoto M,Yanagi H,Yura T,Kubota H

    更新日期：2000-12-20 00:00:00