Interaction of myosin subfragment-1 with F- and G-actin in equilibrium.

abstract：:Tumor necrosis factor receptor-associated factor 2 (TRAF2) has been demonstrated that it plays a significant role in cell death receptor signal transduction. The purpose of this study was to investigate the expression of TRAF2 and its possible role in FJOA. We observed an up-regulation of TRAF2 in FJOA by immunohistoc...

journal_title：Biochemical and biophysical research communications

authors： Jiang J,Zhang J,Wu C,Guo X,Chen C,Bao G,Sun Y,Chen J,Xue P,Xu G,Cui Z

更新日期：2018-09-10 00:00:00

abstract：:The relation between platelet-derived growth factor (PDGF)-induced smooth muscle cell migration, measured in Boyden chambers, and cellular arachidonic acid cascade was studied by using rat aortic smooth muscle cells. Partially purified PDGF stimulated cell migration significantly at a concentration of 1.33-133.0 micro...

journal_title：Biochemical and biophysical research communications

authors： Nakao J,Ito H,Chang WC,Koshihara Y,Murota S

更新日期：1983-05-16 00:00:00

abstract：PURPOSE:Recently, the newly identified embryonic stem cell marker, Zinc finger and SCAN domain containing 4 gene (ZSCAN4), which plays a key role in genomic stability by regulating telomere elongation, was shown to co-localize with TRF1 foci. This suggests that the interaction of ZSCAN4 with TRF1 functions in regulatio...

journal_title：Biochemical and biophysical research communications

authors： Lee K,Gollahon LS

更新日期：2015-10-30 00:00:00

abstract：:In our previous report we described the endocytotic incorporation of coffee bean alpha-galactosidase conjugated to human alpha-2-macroglobulin (alpha-2-M) into cultured fibroblasts derived from a patient with Fabry's disease (1). The fate of internalized alpha-galactosidase according to the method described in the abo...

journal_title：Biochemical and biophysical research communications

authors： Osada T,Kuroda Y,Ikai A

更新日期：1987-03-30 00:00:00

abstract：:The aim of current study was to elucidate whether aquaporin-9 (AQP9) expression was involved in the progression of bone loss induced by microgravity. We used the hind-limb suspension (HLS) mice model to simulate microgravity and induce bone loss. It was found that HLS exposure decreased femur bone mineral density (BMD...

journal_title：Biochemical and biophysical research communications

authors： Bu G,Shuang F,Wu Y,Ren D,Hou S

更新日期：2012-03-23 00:00:00

abstract：:The presence of at least two distinct Mg2+- or Mn2+-dependent, Ca2+-independent endonuclease activities was shown in the myeloid leukemia cell line P39. One of them was recovered from nuclear extracts and the other from a cytoplasmic fraction. The molecular size of the former was 30 kDa in both gel filtration and acti...

journal_title：Biochemical and biophysical research communications

authors： Kawabata H,Anzai N,Masutani H,Hirama T,Hishita T,Dodo M,Masuda T,Yoshida Y,Okuma M

更新日期：1997-04-07 00:00:00

abstract：:Alternative splicing is a major mechanism regulating pattern of gene expression through the production of multiple mRNAs from a single gene transcript. Any misregulation can cause various human diseases and also have severe effects on embryogenesis. SRSF1 is one of the critical factors regulating alternative splicing ...

journal_title：Biochemical and biophysical research communications

authors： Lee SH,Lee HK,Kim C,Kim YK,Ismail T,Jeong Y,Park K,Park JW,Kwon OS,Kang BS,Lee DS,Park MJ,Park DS,Lee HS

更新日期：2016-09-02 00:00:00

abstract：:Extracellular superoxide dismutase (EC-SOD) is the major isozyme of SOD in arteries, but is also abundant in lungs. In particular, mouse lungs contain large amounts of EC-SOD compared to lungs in other mammals. This suggests that EC-SOD may have an amplified function in the mouse lung. This study describes the purific...

journal_title：Biochemical and biophysical research communications

authors： Fattman CL,Enghild JJ,Crapo JD,Schaefer LM,Valnickova Z,Oury TD

更新日期：2000-08-28 00:00:00

abstract：:Biotin protein ligase (BPL) is an enzyme mediating biotinylation of a specific lysine residue of the carboxyl carrier protein (BCCP) of biotin-dependent enzymes. We recently found that the substrate specificity of BPL from archaeon Sulfolobus tokodaii is totally different from those of many other organisms, in reflect...

journal_title：Biochemical and biophysical research communications

authors： Sueda S,Li YQ,Kondo H,Kawarabayasi Y

更新日期：2006-05-26 00:00:00

abstract：:Lipopolysaccharide (LPS) stimulates macrophages by activating NF-kappaB, which contributes to the release of tumor necrosis factor (TNF)-alpha and interleukin (IL)-6. 1,5-Anhydro-D-fructose (1,5-AF), a monosaccharide formed from starch and glycogen, exhibits anti-oxidant activity and enhances insulin secretion. This s...

journal_title：Biochemical and biophysical research communications

authors： Meng X,Kawahara K,Nawa Y,Miura N,Shrestha B,Tancharoen S,Sameshima H,Hashiguchi T,Maruyama I

更新日期：2009-03-06 00:00:00

abstract：:Capsaicin has been reported to regulate blood glucose levels and to ameliorate insulin resistance in obese mice. This study demonstrates that capsaicin increases glucose uptake directly by activating AMP-activated protein kinase (AMPK) in C2C12 muscle cells, which manifested as an attenuation of glucose uptake when co...

journal_title：Biochemical and biophysical research communications

authors： Kim SH,Hwang JT,Park HS,Kwon DY,Kim MS

更新日期：2013-09-13 00:00:00

abstract：:The earthworm Lumbricus rubellus has been found to inhabit cadmium-rich soils and accumulate cadmium within its tissues. Two metallothionein (MT) isoforms (1 and 2) have been identified and cloned from L. rubellus. In this study, we address the metalation status, metal coordination, and structure of recombinant MT-2 f...

journal_title：Biochemical and biophysical research communications

authors： Ngu TT,Sturzenbaum SR,Stillman MJ

更新日期：2006-12-08 00:00:00

abstract：:MicroRNAs (miRNAs) are small RNA molecules, which act as post-transcriptional regulators of a gene expression, with important functions within the cell physiology. Whilst many authors have focused on the study of miRNA expression in physiological and pathological processes, various technical variables related to miRNA...

journal_title：Biochemical and biophysical research communications

authors： Mraz M,Malinova K,Mayer J,Pospisilova S

更新日期：2009-12-04 00:00:00

abstract：:SMRT acts as a corepressor for a range of transcription factors. The amino-terminal part of the protein includes domains that mainly mediate transcriptional repression whilst the carboxy-terminal part includes domains that interact with nuclear receptors using up to three motifs called CoRNR boxes. The region of the S...

journal_title：Biochemical and biophysical research communications

authors： Short S,Malartre M,Sharpe C

更新日期：2005-09-02 00:00:00

abstract：:Mab21 gene family members are required for embryonic development and sensory organ formation in both invertebrates and vertebrates. However, their mechanistic role on differentiation is largely unexplored. We report here the isolation of SIN-3 as a MAB-21 interacting molecule. sin-3 is co-expressed with mab-21 in the ...

journal_title：Biochemical and biophysical research communications

authors： Choy SW,Wong YM,Ho SH,Chow KL

更新日期：2007-07-06 00:00:00

abstract：:Enhancer sequences analysed using the informational spectrum method (ISM) show a characteristic frequency at .0488. It has been shown that the characteristic frequency for some DNA binding proteins overlaps the characteristic frequency of their target DNA sequences. We suggest here that two types of proteins, homeopro...

journal_title：Biochemical and biophysical research communications

authors： Cosić I,Nesić D,Pavlović M,Williams R

更新日期：1986-12-15 00:00:00

abstract：:We have studied the convergence of the biosynthetic lysosomal route marked by the newly synthesized lysosomal enzyme arylsulfatase A (ASA) with the endosomal/prelysosomal compartment in ASA overexpressing baby hamster kidney (BHK) cells. A monoclonal antibody against ASA conjugated to transferrin (Tf-alpha ASA) was us...

journal_title：Biochemical and biophysical research communications

authors： Diesner F,Sommerlade HJ,Braulke T

更新日期：1993-11-30 00:00:00

abstract：:Fluorimetry and spectrophotometry have been used to study the binding of dimethyl, dipropyl, dibutyl and diphenylnitrosamine to nicotinic acetylcholine receptor isolated, and purified, from Torpedo fuscomaculata. Scatchard analysis indicates that all four ligands are true agonists of the receptor exhibiting positive c...

journal_title：Biochemical and biophysical research communications

authors： Kapp EA,Daya S,Whiteley CG

更新日期：1990-03-30 00:00:00

abstract：:Endothelin (200 nM) evoked a rapid rise in [Ca2+]i which was then followed by a maintained elevation of [Ca2+]i. The initial transient can be explained by the release of stored Ca2+ whilst the maintained plateau is likely to be an influx of Ca2+ as it was partially inhibited by nifedipine (5 microM) and the remaining ...

journal_title：Biochemical and biophysical research communications

authors： Simpson AW,Ashley CC

更新日期：1989-09-29 00:00:00

abstract：:Some of the effects of several oncogenes, integrins, growth factors, and neuropeptides are mediated by tyrosine phosphorylation of the non-receptor tyrosine kinase p125(FAK) and the cytoskeletal protein paxillin. We have demonstrated that different stimuli cause tyrosine phosphorylation of p125(FAK) and paxillin in ra...

journal_title：Biochemical and biophysical research communications

authors： García-Benito M,San Román JI,López MA,García-Marín LJ,Calvo JJ

更新日期：2000-08-11 00:00:00

abstract：:Coxsackievirus A24 (CVA24) is responsible for acute hemorrhagic conjunctivitis, a highly contagious eye disease for which no prevention or treatment is currently available. We thus assessed the antiviral potential of a small interfering RNA (siRNA) targeting CVA24. HeLa cells with or without four different siRNAs comp...

journal_title：Biochemical and biophysical research communications

authors： Jun EJ,Nam YR,Ahn J,Tchah H,Joo CH,Jee Y,Kim YK,Lee H

更新日期：2008-11-14 00:00:00

abstract：:Pterostilbene, a bioactive component of blueberries and grapes, shows structural similarity to resveratrol, and exhibits antioxidant, anti-inflammatory, anti-cancer, hypoglycemic, and cholesterol lowering effects. Recent evidence indicates that pterostilbene is an agonist of the nuclear receptor, peroxisome proliferat...

journal_title：Biochemical and biophysical research communications

authors： Ren G,Rimando AM,Mathews ST

更新日期：2018-04-06 00:00:00

abstract：:Exocytosis is regulated by exocytotic proteins, which are present in insulin-secreting beta-cells and play regulatory roles in insulin secretion. Non-insulin dependent diabetes mellitus (type 2 diabetes) is a disease characterized by impaired insulin secretion and insulin resistance. Exocytotic protein immunoreactivit...

journal_title：Biochemical and biophysical research communications

authors： Zhang W,Khan A,Ostenson CG,Berggren PO,Efendic S,Meister B

更新日期：2002-03-08 00:00:00

abstract：:The gene encoding a red-shifted green fluorescent protein variant (EGFP) was introduced into a human immunodeficiency virus type 1 (HIV-1) molecular clone by replacing the nef gene. The EGFP-expressing HIV-1 replicated efficiently in established human T cells. The expression of EGFP in the virus-infected cells was con...

journal_title：Biochemical and biophysical research communications

authors： Lee AH,Han JM,Sung YC

更新日期：1997-04-07 00:00:00

abstract：:Most proteins synthesized in cytoplasm target to mitochondria through sequences at their amino termini. However, a previous study suggests that the native carboxyl terminus of ISP6 might be critical of its specific delivery. Here we investigated the sequence directing ISP6 to yeast mitochondrial outer membrane. Unlike...

journal_title：Biochemical and biophysical research communications

authors： Cao W,Douglas MG

更新日期：1996-07-16 00:00:00

abstract：:Using a highly purified preparation of glycine methyltransferase mRNA, double-stranded cDNA was synthesized and inserted into the PstI site of pBR322. The resulting recombinant DNA was used to transform E. coli X 1776 by conventional methods. Among tetracycline-resistant transformants, a number of colonies were found ...

journal_title：Biochemical and biophysical research communications

authors： Ogawa H,Gomi T,Horii T,Ogawa H,Fujioka M

更新日期：1984-10-15 00:00:00

abstract：:Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Circular RNAs (circRNAs) are involved in regulating various biological processes. This study aimed to explore the role and molecular basis of hsa_circ_0006872 in cigarette smoke extract (CSE)-induced cell injury. HPMECs and BEAS-2B cells...

journal_title：Biochemical and biophysical research communications

authors： Xue M,Peng N,Zhu X,Zhang H

更新日期：2021-01-01 00:00:00

abstract：:The aim of this study was to investigate the response to and the physiological consequences of copper-mediated cross-linking of S100A2 and S100A4, two members of the S100 family of EF-hand calcium-binding proteins. As demonstrated by electrophoresis and mass spectrometry techniques S100A2 and S100A4 show formation of ...

journal_title：Biochemical and biophysical research communications

authors： Haase-Kohn C,Wolf S,Lenk J,Pietzsch J

更新日期：2011-09-30 00:00:00

abstract：:Cytoplasmic polyadenylation element binding (CPEB) proteins are RNA-binding proteins involved in translational regulation of the specific target mRNAs and control function of various organs including brain, liver and hematopoietic system. However, the role of CPEB proteins during osteoclast differentiation remains unc...

journal_title：Biochemical and biophysical research communications

authors： Arasaki Y,Li M,Akiya T,Nozawa I,Ezura Y,Hayata T

更新日期：2020-08-06 00:00:00

abstract：:There is increasing evidence to suggest that Ca2+-calmodulin dependent protein kinase (CaMK) regulates the sarcoplasmic reticulum (SR) function and thus plays an important role in modulating the cardiac performance. Because intracellular Ca2+-overload is an important factor underlying cardiac dysfunction in a heart di...

journal_title：Biochemical and biophysical research communications

authors： Netticadan T,Temsah RM,Kawabata K,Dhalla NS

更新日期：2002-05-03 00:00:00