Abstract：
:A novel bioactive lipid, cyclic phosphatidic acid (cPA), was identified in lipids bound to human serum albumin. A cPA fraction was extracted and purified from human serum albumin by use of a combination of preparative TLC and HPLC. Electrospray ionization mass spectrometry of the purified fraction showed molecular ions corresponding to cPA, which was composed of some different fatty acid species. The most abundant component was identified as palmitoyl-cPA by tandem mass spectrometry using collision-induced dissociation. These data have established that cPA is a naturally occurring lipid bound to human serum albumin.
journal_name
Life Scijournal_title
Life sciencesauthors
Kobayashi T,Tanaka-Ishii R,Taguchi R,Ikezawa H,Murakami-Murofushi Kdoi
10.1016/s0024-3205(99)00483-xsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
2185-91issue
21eissn
0024-3205issn
1879-0631pii
S002432059900483Xjournal_volume
65pub_type
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