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Development of vacuous chewing movements in rats: role of housing environment.

Abstract：

:The influence of stressful experiences on the development of vacuous chewing movements (VCM) was investigated in non-medicated rats. After an initial baseline period one group of rats was housed in a noisy environment while another group was housed in quiet surroundings. The development of VCM was recorded during a 16 week period. The animals subjected to uncontrollable noise developed significantly more VCM compared with the control animals. The results are consistent with the idea that stress can sentize a behaviour which is usually connected with the nigrostriatal dopaminergic system. This underscores the essential role of the housing environment as a parameter during behavioural studies of the dopaminergic system, as for example studies of VCM in neuroleptic treated rats.

journal_name

Life Sci

journal_title

Life sciences

authors

Glenthøj B,Hemmingsen R

doi

10.1016/0024-3205(91)90146-3

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

2137-40

issue

22

eissn

0024-3205

issn

1879-0631

pii

0024-3205(91)90146-3

journal_volume

48

pub_type

杂志文章

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