Effects of monosodium glutamate on lines of chickens having different juvenile exponential growth rates.

Abstract:

:MSG (4 mg/g BW) or the equivalent molar ratio of NaCl were injected subcutaneously into chicks from four populations of chickens derived from a double selection experiment [(1) low exponential growth rate (EGR) to 14 days of age (14L), (2) high EGR to 14 days of age (14H), (3) low EGR to 42 days of age (42L) and high EGR to 42 days of age (42H)]. MSG significantly influenced growth in chickens, but the absolute effect was genotype and sex dependent. Weights of abdominal fat pads were ranked among lines according to the sequence 42H, 14H, 42L and 14L. MSG significantly increased fat pad size by 51%, independent of genotype or sex. MSG significantly decreased breast weight in females and males by 7%. The higher percent fat pads and lower breast weights associated with MSG are indicative of growth due to fat accretion rather than protein deposition.

journal_name

Life Sci

journal_title

Life sciences

authors

Sizemore FG,Barbato GF

doi

10.1016/0024-3205(91)90061-f

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

1659-65

issue

22

eissn

0024-3205

issn

1879-0631

pii

0024-3205(91)90061-F

journal_volume

49

pub_type

杂志文章
  • Differential inhibitory effects of sophoricoside analogs on bioactivity of several cytokines.

    abstract::Effects of sophoricoside and its analogs on proinflammatory cytokines have been investigated. Sophoricoside, genistein and orobol exhibited inhibitory effects on IL-5, IL-3, GM-CSF and IL-6 bioactivities. Genistin showed inhibitory effects on IL-5 and IL-3 bioactivities, but did not inhibit GM-CSF and IL-6 bioactiviti...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(00)00873-0

    authors: Yun J,Lee CK,Chang IM,Takatsu K,Hirano T,Min KR,Lee MK,Kim Y

    更新日期:2000-10-27 00:00:00

  • Epinephrine sulfation in the forearm: arteriovenous differences in free and conjugated catecholamines.

    abstract::Simultaneously drawn arterial and forearm venous levels of free and sulfate conjugated epinephrine and norepinephrine were measured in 8 subjects in order to study the role of skeletal muscle in catecholamine sulfation. A sensitive radioenzymatic assay was used. The average free epinephrine level was 46% lower in veno...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(82)90758-5

    authors: Joyce DA,Beilin LJ,Vandongen R,Davidson L

    更新日期:1982-11-29 00:00:00

  • Studies on methyl-xanthines in intact and hypophysectomised rats: differences in pharmacokinetics and adrenocortical response.

    abstract::The effects of caffeine (Cf), theophylline (Tph) and theobromine (Tb) on the adrenal cortex were studied. No direct effect (hypophysectomized: hypo(-) rats) was observed with any of the three methyl-xanthines (MX) after chronic oral administration (5 days). An indirect effect (via the hypothalamo-hypophyseal-adrenal a...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(85)90131-6

    authors: Okyayuz GI,Ventura MA,Gardey C,Rey E,Thiroux G

    更新日期:1985-09-30 00:00:00

  • iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibility.

    abstract:AIMS:Major depressive disorder, as a destructive mental health disorder, is a major contributor to disability and death. Numerous studies have illustrated that activation of inflammation and fluctuating immune reactions play a crucial role in the physiopathology of depression. The effectiveness of antidepressants is af...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2020.118501

    authors: Lan T,Bai M,Chen X,Wang Y,Li Y,Tian Y,He Y,Wu Z,Yu H,Chen Z,Chen C,Yu Y,Cheng K,Xie P

    更新日期:2020-12-01 00:00:00

  • Analysis of heart rate variability-related indexes in the interictal period in patients with focal epilepsy.

    abstract:AIMS:Changes in cardiac autonomic nervous function have been evaluated by studying the related indexes of heart rate variability (HRV) in patients with focal epilepsy (FE) in the interictal period. MAIN METHODS:A total of 30 FE patients who were treated in our department from July 2015 to May 2017, were included into ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2018.08.033

    authors: Yu YL,Li NN,Shi MT,Lu HJ

    更新日期:2018-09-15 00:00:00

  • The interaction of RAAS inhibitors with COVID-19: Current progress, perspective and future.

    abstract::Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently defined as the worst pandemic disease. SARS-CoV-2 infects human cells via the binding of its S protein to the receptor angiotensin-converting enzyme (ACE2). The use of ACEIs/ARBs (RAAS inhibitors) ...

    journal_title:Life sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.lfs.2020.118142

    authors: Zhang J,Wang M,Ding W,Wan J

    更新日期:2020-09-15 00:00:00

  • Protein kinase C inhibitor chelerythrine attenuates the morphine-induced excitatory amino acid release and reduction of the antinociceptive effect of morphine in rats injected intrathecally with pertussis toxin.

    abstract::Neuropathic pain syndromes respond poorly to opioid treatment. In our previous studies, we found that intrathecal (i.t.) injection of pertussis toxin (PTX) produces thermal hyperalgesia, which is poorly responsive to morphine and is accompanied by an increase in cerebrospinal fluid (CSF) levels of excitatory amino aci...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2005.08.020

    authors: Wu GJ,Wen ZH,Chang YC,Yang SN,Tao PL,Wong CS

    更新日期:2006-03-13 00:00:00

  • Prostaglandin E(2) and I(2) facilitate noxious heat-induced spike discharge but not iCGRP release from rat cutaneous nociceptors.

    abstract::The bradykinin-induced sensitization of cutaneous nociceptors to heat was previously shown to be abolished by cyclooxygenase blockade suggesting that endogenous prostaglandins exerted a heat-sensitizing action. The present study aimed at investigating the effects of exogenous prostaglandin E(2) (PGE(2)) and I(2) (PGI(...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2007.10.001

    authors: Derow A,Izydorczyk I,Kuhn A,Reeh PW,Petho G

    更新日期:2007-12-14 00:00:00

  • L-dopa is protective against indomethacin-induced small intestinal ulceration in the rat: possible role of an alpha-2-adrenergic mechanism.

    abstract::Dopaminergic agents ameliorate experimentally induced gastroduodenal mucosal injury, but there is no information about their effect on small intestinal mucosa. We studied the effect of L-dopa and related substances on indomethacin-induced intestinal ulceration in the rat. Ulceration was produced by s.c. injection of 3...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(92)90517-s

    authors: Kiro A,Zahavi I,Marcus H,Dinari G

    更新日期:1992-01-01 00:00:00

  • Gangliosides, or sialic acid, antagonize ethanol intoxication.

    abstract::Because ethanol elicits a dose-dependent hydrolysis of brain sialogangliosides, we tested the possibility that injected gangliosides might antagonize intoxicating doses of ethanol. Clear anti-intoxication effects were seen at 24 hr post-injection of mixed mouse-brain gangliosides at 125-130 mg/kg, but not at lower or ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(88)90284-6

    authors: Klemm WR,Boyles R,Mathew J,Cherian L

    更新日期:1988-01-01 00:00:00

  • Neurotensin enhances plasma adrenocorticotropin concentration by stimulating corticotropin-releasing hormone secretion.

    abstract::The systemic administration of neurotensin (NT) dose-dependently increased plasma adrenocorticotropin (ACTH) concentration in rats, and this effect was annulled by (alpha-helical)-CRH9-41, an antagonist of corticotropin-releasing hormone (CRH). The systemic administration of [D-Trp11]-neurotensin (NT-A), a specific NT...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(92)90250-s

    authors: Nussdorfer GG,Malendowicz LK,Meneghelli V,Mazzocchi G

    更新日期:1992-01-01 00:00:00

  • Inhibiting Rab27a in renal tubular epithelial cells attenuates the inflammation of diabetic kidney disease through the miR-26a-5p/CHAC1/NF-kB pathway.

    abstract::The effect of exosomes on receptor cells participating in intercellular communication has been extensively studied, but the effect of exosomes on donor cells remains unclear. It has been reported that exosomes secreted by renal proximal tubular epithelial cells (PTECs) under different stimuli accelerate acute and chro...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2020.118347

    authors: Li S,Jia Y,Xue M,Hu F,Zheng Z,Zhang S,Ren S,Yang Y,Si Z,Wang L,Guan M,Xue Y

    更新日期:2020-11-15 00:00:00

  • Effects of hypersecretion of growth hormone and prolactin on plasma levels of glucagon and insulin in GH3-cell-tumor-bearing rats, and the influence of bromocriptine treatment.

    abstract::Plasma levels of prolactin, growth hormone, glucagon insulin and glucose were measured in non-treated control rats, bromocriptine-treated control rats and GH3-cell-tumor-bearing rats with and without bromocriptine treatment. Bromocriptine treatment increased plasma levels of glucagon, insulin and glucose in control ra...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(86)90042-1

    authors: Knudtzon J,Johansen PW,Haug E,Gautvik K

    更新日期:1986-08-18 00:00:00

  • Effects of dopamine metabolites on locomotor activities and on the binding of dopamine: relevance to the side effects of L-dopa.

    abstract::L-dopa is the major treatment for Parkinson's disease (PD), but its efficacy is limited by the presence of dyskinesia. The dyskinesia develops over a period of exposure to L-dopa and is related to the dosage, therefore, the cause may involve inductive changes that produce toxic levels of metabolites, interfering with ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(00)00543-9

    authors: Charlton CG,Crowell B Jr

    更新日期:2000-04-21 00:00:00

  • Hemin protects against hippocampal damage following orthotopic autologous liver transplantation in adult rats.

    abstract:AIMS:Induction of heme oxygenase-1 (HO-1) has been widely accepted to be neuro-protective. This study aimed to examine whether hemin (a HO-1 inducer) attenuates neuronal damage in the hippocampus induced by orthotopic autologous liver transplantation (OALT) in adult rats. MAIN METHODS:Rats were randomly allocated into...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2015.05.021

    authors: Wang Y,Xia H,Yu X,Lu T,Chi X,Cai J

    更新日期:2015-08-15 00:00:00

  • Effects of a KiSS-1 peptide, a metastasis suppressor gene, on the invasive ability of renal cell carcinoma cells through a modulation of a matrix metalloproteinase 2 expression.

    abstract::Although effects of a metastasis suppressor gene, KiSS-1, have been postulated to be mediated by its receptor, hOT7T175, the mechanism of such effects remains unknown. This study was designed to evaluate the mechanism of how KiSS-1 works and to assess effects of a synthesized truncated KiSS-1 protein on the invasive a...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2008.06.018

    authors: Yoshioka K,Ohno Y,Horiguchi Y,Ozu C,Namiki K,Tachibana M

    更新日期:2008-08-29 00:00:00

  • Species dependent dual modulation of the benzodiazepine/GABA receptor chloride channel by dihydroergosine.

    abstract::Dihydroergosine (50 and 100 mg/kg) enhanced the incidence of bicuculline (3 mg/kg)-induced convulsions in female rats, while 100 mg/kg of dihydroergosine given to female mice made 45% convulsive dose of bicuculline (2.5 mg/kg) to be subconvulsive. The same dose of dihydroergosine enhanced in mice the latency of bicucu...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(90)90608-t

    authors: Pericić D,Tvrdeić A

    更新日期:1990-01-01 00:00:00

  • Neuropeptides in human cerebrospinal fluid.

    abstract::Ten neuropeptides were measured by RIA in human cerebrospinal fluid obtained from 30 normal volunteers. The levels of seven peptides (corticotropin releasing factor, adrenocorticotropin, vasoactive intestinal peptide, somatostatin, beta-endorphin, beta-lipotropin, and the N-terminal fragment of proopiomelanocortin) we...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(85)90139-0

    authors: Berrettini WH,Nurnberger JI Jr,Gold PW,Chretien M,Chrousos GP,Chan JS,Goldin LR,Gershon ES

    更新日期:1985-09-30 00:00:00

  • Activation of CFTR Cl(-) channel by tyrphostins via a protein tyrosine kinase-independent pathway in forskolin-stimulated renal epithelial A6 cells.

    abstract::We studied effects of tyrphostin A23 (an inhibitor of protein tyrosine kinase; PTK) and tyrphostin A63 (an inactive analog of tyrphostin A23) on forskolin-activated cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels and Cl(-) secretion in renal epithelial A6 cells. Tyrphostin A23 and A63 had no ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(02)01824-6

    authors: Niisato N,Nishio K,Marunaka Y

    更新日期:2002-07-26 00:00:00

  • Interaction of tocopherols and phenolic compounds with membrane lipid components: evaluation of their antioxidant activity in a liposomal model system.

    abstract::This paper describes the use of complex liposomes as real membrane models to evaluate the potential benefits of several antioxidants in relation to lipid peroxidation. The xanthine oxidase/Fe(3+)-ADP-EDTA and the Fe(2+)/H2O2 systems have been used to generate hydroxyl radicals and the water soluble azo-compound 2,2'-a...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(03)00120-6

    authors: Gutiérrez ME,García AF,Africa de Madariaga M,Sagrista ML,Casadó FJ,Mora M

    更新日期:2003-04-11 00:00:00

  • Effects of felbamate, kynurenic acid derivatives and NMDA antagonists on in vitro kainate-induced epileptiform activity.

    abstract::The effects of the novel anticonvulsant felbamate, which binds to the 5-7 dichlorokynurenic binding sites, were tested towards the CA1 epileptiform activity induced in rat hippocampal slices by kainic acid. The effects of the kynurenic acid derivatives 7-chlorokynurenic acid and 5-7 dichlorokynurenic acid and of the N...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(96)00251-2

    authors: Domenici MR,Marinelli S,Sagratella S

    更新日期:1996-05-24 00:00:00

  • L-tryptophan attenuation of the dopaminergic and behavioral responses to cocaine.

    abstract::This study assessed the effects of acute intravenous L-tryptophan (neutral amino acid precursor for serotonin) administration on cocaine-induced dopaminergic responses. Male Sprague-Dawley rats were surgically implanted with guide cannulas in the nucleus accumbens 5 days prior to the study and with vascular catheters ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(01)01276-0

    authors: Molina PE,Ahmed N,Gatley J,Volkow ND,Abumrad NN

    更新日期:2001-09-07 00:00:00

  • Chronic treatment of DA-8159, a new phosphodiesterase type V inhibitor, attenuates endothelial dysfunction in stroke-prone spontaneously hypertensive rat.

    abstract::This study examined the effects of chronic treatment of a new phosphodiesterase type 5 inhibitor, DA-8159, on endothelial dysfunction in stroke-prone spontaneously hypertensive rats (SHR-SP). Six-week-old male SHR-SP were divided into 4 groups; vehicle control, DA-8159 1, 3, and 10 mg/kg/day. During a 32-week experime...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2005.06.042

    authors: Choi SM,Kim JE,Kang KK

    更新日期:2006-02-09 00:00:00

  • Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.

    abstract::The aim of this study was to investigate whether the A1/A2 receptor agonist, 5'-N-ethylcarboxamidoadenosine (NECA), and the selective A1 agonist, N6-cyclopentyladenosine (CPA), induced physical dependence by quantifying specific antagonist-precipitated withdrawal syndromes in conscious rats. In addition, the presence ...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(01)01155-9

    authors: Coupar IM,Tran BL

    更新日期:2001-07-06 00:00:00

  • The importance of estrogen for bone protection in experimental hyperthyroidism in human osteoblasts.

    abstract::Triiodothyronine (T3) and estrogen (E2) play important roles in the bone remodeling process and signaling of receptor activator of the nuclear factor-kappa β (RANKL) and osteoprotegerin (OPG) expressed by osteoblasts. However, little is known of the molecular action of these hormones in conditions of hyperthyroidism a...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2019.116556

    authors: Olímpio RMC,Moretto FCF,De Sibio MT,de Oliveira M,Mathias LS,Gonçalves BM,Deprá IC,Tilli HP,Rodrigues BM,Saraiva PP,Maria DA,Nogueira CR

    更新日期:2019-08-15 00:00:00

  • V2-receptor blockade enhances pressor response to vasopressin: gender difference.

    abstract::The present study was performed to determine if the attenuated pressor response to vasopressin in conscious non-estrous female rats is due in part to an enhanced V2-like receptor vasodilator action. In male rats, infusion of vasopressin at a rate of 1 ng.min(-1).kg body weight-1 (wt) resulted in an increase in mean ar...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(96)00351-7

    authors: Wang YX,Crofton JT,Liu H,Sato K,Share L

    更新日期:1996-01-01 00:00:00

  • Unexpected opioid activity in a known class of drug.

    abstract::Tifluadom, although structurally a 1,4 benzodiazepine, has no affinity for the 3H-flunitrazepam binding site, but is a potent displacer of 3H-bremazocine from its opioid binding site. Tifluadom is characterised as an opiate kappa-receptor agonist in vitro and in vivo with potent analgesic activity in animals and no de...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(82)90346-0

    authors: Römer D,Büscher HH,Hill RC,Maurer R,Petcher TJ,Zeugner H,Benson W,Finner E,Milkowski W,Thies PW

    更新日期:1982-09-20 00:00:00

  • Tricyclic antidepressant drugs affect histamine receptors in human leukocytes.

    abstract::Tricyclic antidepressant drugs bind to histamine receptors in rodent and other mammalian tissues. However, a readily accessible, normal human tissue for studies of these drugs has not been available. We showed that freshly isolated human leukocytes can be used for this purpose. Following isolation by dextran sedimenta...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/0024-3205(84)90441-7

    authors: Sadava D,Wilmington K

    更新日期:1984-12-17 00:00:00

  • Effect of acetylsalicylic acid on inflamed adipose tissue. Insulin resistance and hepatic steatosis in a mouse model of diet-induced obesity.

    abstract:AIMS:Obesity represents a global health problem. Excessive caloric intake promotes the release of inflammatory mediators by hypertrophic adipocytes and obesity-induced inflammation is now recognized as a risk factor for the development of several diseases, such as cardiovascular diseases, insulin resistance, type-II di...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/j.lfs.2020.118618

    authors: Sardi C,Martini E,Mello T,Camelliti S,Sfondrini L,Marcucci F,Kallikourdis M,Sommariva M,Rumio C

    更新日期:2021-01-01 00:00:00

  • ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells.

    abstract::Dehydroepiandrosterone (DHEA), a major steroid secreted by the adrenal gland, is known to have antiproliferative effects but the mechanism is unclear. We recently reported that DHEA induces growth inhibition and apoptosis in BV-2 cells and these effects are inversely associated with glucose concentrations in the mediu...

    journal_title:Life sciences

    pub_type: 杂志文章

    doi:10.1016/s0024-3205(01)01542-9

    authors: Yang NC,Jeng KC,Ho WM,Hu ML

    更新日期:2002-03-15 00:00:00