Neuropeptides in human cerebrospinal fluid.

Abstract:

:Ten neuropeptides were measured by RIA in human cerebrospinal fluid obtained from 30 normal volunteers. The levels of seven peptides (corticotropin releasing factor, adrenocorticotropin, vasoactive intestinal peptide, somatostatin, beta-endorphin, beta-lipotropin, and the N-terminal fragment of proopiomelanocortin) were highly, positively correlated with one another. This result is consistent with the hypothesis that cerebrospinal fluid levels of these seven peptides are a function of some common regulatory factor, such as shared release into the cerebrospinal fluid.

journal_name

Life Sci

journal_title

Life sciences

authors

Berrettini WH,Nurnberger JI Jr,Gold PW,Chretien M,Chrousos GP,Chan JS,Goldin LR,Gershon ES

doi

10.1016/0024-3205(85)90139-0

subject

Has Abstract

pub_date

1985-09-30 00:00:00

pages

1265-70

issue

13

eissn

0024-3205

issn

1879-0631

pii

0024-3205(85)90139-0

journal_volume

37

pub_type

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